National Institute of Genetics

Summary

Organization: National Institute of Genetics
Country: Japan

Top Publications

  1. doi DDK phosphorylates checkpoint clamp component Rad9 and promotes its release from damaged chromatin
    Kanji Furuya
    Microbial Genetics Laboratory, Genetic Strains Research Center, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411 8540, Japan
    Mol Cell 40:606-18. 2010
  2. ncbi Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system
    Hiroki Kokubo
    Division of Mammalian Development, National Institute of Genetics, Mishima, Shizuoka, Japan
    Dev Biol 278:301-9. 2005
  3. ncbi [International public gene expression database (CIBEX) and data submission]
    Yoshio Tateno
    Tanpakushitsu Kakusan Koso 49:2678-83. 2004
  4. ncbi Biological ontologies in rice databases. An introduction to the activities in Gramene and Oryzabase
    Yukiko Yamazaki
    Center for Genetic Resource Information, National Institute of Genetics, Mishima, Shizuoka, 411 8540 Japan
    Plant Cell Physiol 46:63-8. 2005
  5. ncbi Glyceraldehyde-3-phosphate dehydrogenase and actin associate with RNA polymerase II and interact with its Rpb7 subunit
    Hiroshi Mitsuzawa
    Department of Molecular Genetics, National Institute of Genetics, Mishima, Shizuoka 411 8540, Japan
    FEBS Lett 579:48-52. 2005
  6. ncbi Evolution of hominoids and the search for a genetic basis for creating humanness
    N Saitou
    Division of Population Genetics, National Institute of Genetics, Mishima, Japan
    Cytogenet Genome Res 108:16-21. 2005
  7. ncbi Predicting absolute contact numbers of native protein structure from amino acid sequence
    Akira R Kinjo
    Center for Information Biology and DNA Data Bank of Japan, National Institute of Genetics, Mishima, Japan
    Proteins 58:158-65. 2005
  8. ncbi [The transposon-mediated gene trap method in Zebrafish]
    Tomoya Kotani
    Tanpakushitsu Kakusan Koso 49:2111-6. 2004
  9. ncbi Three-dimensional window analysis for detecting positive selection at structural regions of proteins
    Yoshiyuki Suzuki
    Center for Information Biology and DNA Data Bank of Japan, National Institute of Genetics, Mishima shi, Shizuoka ken, Japan
    Mol Biol Evol 21:2352-9. 2004
  10. ncbi Excision of the Tol2 transposable element of the medaka fish Oryzias latipes in Xenopus laevis and Xenopus tropicalis
    Koichi Kawakami
    Division of Molecular and Developmental Biology, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411 8540, Japan
    Gene 338:93-8. 2004

Research Grants

  1. Genetic methods using the Tol2 transposable element
    Koichi Kawakami; Fiscal Year: 2006

Detail Information

Publications62

  1. doi DDK phosphorylates checkpoint clamp component Rad9 and promotes its release from damaged chromatin
    Kanji Furuya
    Microbial Genetics Laboratory, Genetic Strains Research Center, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411 8540, Japan
    Mol Cell 40:606-18. 2010
    ..We propose that Rad9 phosphorylation by DDK releases Rad9 from DNA damage sites to facilitate DNA repair...
  2. ncbi Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system
    Hiroki Kokubo
    Division of Mammalian Development, National Institute of Genetics, Mishima, Shizuoka, Japan
    Dev Biol 278:301-9. 2005
    ..Taken together, our results demonstrate a requirement for hesr1 and hesr2 in mediating Notch signaling in the developing cardiac and vascular systems...
  3. ncbi [International public gene expression database (CIBEX) and data submission]
    Yoshio Tateno
    Tanpakushitsu Kakusan Koso 49:2678-83. 2004
  4. ncbi Biological ontologies in rice databases. An introduction to the activities in Gramene and Oryzabase
    Yukiko Yamazaki
    Center for Genetic Resource Information, National Institute of Genetics, Mishima, Shizuoka, 411 8540 Japan
    Plant Cell Physiol 46:63-8. 2005
    ..In this mini-review, we introduce activities in Gramene and Oryzabase, which provide biological ontologies for Oryza sativa (rice)...
  5. ncbi Glyceraldehyde-3-phosphate dehydrogenase and actin associate with RNA polymerase II and interact with its Rpb7 subunit
    Hiroshi Mitsuzawa
    Department of Molecular Genetics, National Institute of Genetics, Mishima, Shizuoka 411 8540, Japan
    FEBS Lett 579:48-52. 2005
    ..In addition, GAPDH was affinity-purified from S. pombe extract by using an Rpb4/Rpb7-coupled column. We also identified actin as a pol II-associated protein and revealed the interaction between actin and Rpb7...
  6. ncbi Evolution of hominoids and the search for a genetic basis for creating humanness
    N Saitou
    Division of Population Genetics, National Institute of Genetics, Mishima, Japan
    Cytogenet Genome Res 108:16-21. 2005
    ..It is argued that approximately 10,000 genetic changes are responsible for creating human specific phenotypes. A genome-wide comparison is necessary to decipher those changes...
  7. ncbi Predicting absolute contact numbers of native protein structure from amino acid sequence
    Akira R Kinjo
    Center for Information Biology and DNA Data Bank of Japan, National Institute of Genetics, Mishima, Japan
    Proteins 58:158-65. 2005
    ..The difference between accessible surface area and contact number from a prediction viewpoint and the application of contact number prediction to three-dimensional structure prediction are discussed...
  8. ncbi [The transposon-mediated gene trap method in Zebrafish]
    Tomoya Kotani
    Tanpakushitsu Kakusan Koso 49:2111-6. 2004
  9. ncbi Three-dimensional window analysis for detecting positive selection at structural regions of proteins
    Yoshiyuki Suzuki
    Center for Information Biology and DNA Data Bank of Japan, National Institute of Genetics, Mishima shi, Shizuoka ken, Japan
    Mol Biol Evol 21:2352-9. 2004
    ..This method, however, may fail to detect selection when it operates only on a particular site, in which case single-site analysis may be preferred, although a large number of sequences is required...
  10. ncbi Excision of the Tol2 transposable element of the medaka fish Oryzias latipes in Xenopus laevis and Xenopus tropicalis
    Koichi Kawakami
    Division of Molecular and Developmental Biology, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411 8540, Japan
    Gene 338:93-8. 2004
    ..Our present study suggests that the Tol2 transposon system should be used as a novel genetic tool to develop transgenesis and mutagenesis methods in Xenopus...
  11. ncbi A transposon-mediated gene trap approach identifies developmentally regulated genes in zebrafish
    Koichi Kawakami
    Division of Molecular and Developmental Biology, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411 8540, Japan
    Dev Cell 7:133-44. 2004
    ..We propose our gene trap approach should facilitate studies of vertebrate development and organogenesis...
  12. ncbi Three digestive movements in Hydra regulated by the diffuse nerve net in the body column
    Hiroshi Shimizu
    Dept of Developmental Genetics, National Institute of Genetics, Yata 1, 111, 411 8540 Mishima, Japan
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 190:623-30. 2004
    ..Overall, these observations suggest that the digestive process in Hydra is dynamic and that the diffuse nerve net regulates the digestive movements as a primitive form of enteric nervous system...
  13. ncbi The phylogenetic relationship of tetrapod, coelacanth, and lungfish revealed by the sequences of forty-four nuclear genes
    Naoko Takezaki
    Max Planck Institut fur Biologie, Abteilung Immungenetik, Corrensstrasse Tübingen, Germany
    Mol Biol Evol 21:1512-24. 2004
    ..Apparently, the coelacanth, lungfish, and tetrapod lineages diverged within such a short time interval that at this level of analysis, their relationships appear to be an irresolvable trichotomy...
  14. ncbi Assembly of kinetochores in vertebrate cells
    Tatsuo Fukagawa
    PRESTO, the Japan Science and Technology Agency JST, National Institute of Genetics and The Graduate University for Advanced Studies, Mishima, Shizuoka 411 8540, Japan
    Exp Cell Res 296:21-7. 2004
    ..In this review, I will focus on recent advances in our understanding of centromere DNAs as sites for kinetochore assembly and the mechanism underlying kinetochore assembly in vertebrate cells...
  15. ncbi Identification of differentially expressed genes in psoriasis using expression profiling approaches
    K Itoh
    Laboratory for Gene Expression Analysis, Center for Information Biology, National Institute of Genetics, Mishima, Shizuoka, Japan
    Exp Dermatol 14:667-74. 2005
    ..These seven genes, which were reported to be related to apoptosis or antiproliferation, might have causal roles in pathophysiology in psoriasis...
  16. ncbi Transposon tools and methods in zebrafish
    Koichi Kawakami
    Division of Molecular and Developmental Biology, National Institute of Genetics, Mishima, Shizuoka, Japan
    Dev Dyn 234:244-54. 2005
    ..These methods should increase the usefulness of zebrafish as a model vertebrate and facilitate the study of developmental biology, genetics, and genomics...
  17. ncbi The C. elegans RUNX transcription factor RNT-1/MAB-2 is required for asymmetrical cell division of the T blast cell
    Hiroshi Kagoshima
    Genome Biology Laboratory, National Institute of Genetics, Yata 1111, Mishima, Shizuoka 411 8540, Japan
    Dev Biol 287:262-73. 2005
    ..All our data suggest that RNT-1/MAB-2 functions with POP-1 to control the asymmetry of the T cell division...
  18. doi Dermal morphogenesis controls lateral line patterning during postembryonic development of teleost fish
    Hironori Wada
    Center for Transdisciplinary Research, Niigata University, Igarashi 2, Nishi ku, Niigata 950 2181, Japan
    Dev Biol 340:583-94. 2010
    ..These results strongly suggest a control of postembryonic neuromast patterns by underlying dermal structures. This dermal control may explain some aspects of the evolution of lateral line patterns...
  19. pmc Transposon-mediated BAC transgenesis in zebrafish and mice
    Maximiliano L Suster
    Division of Molecular and Developmental Biology, National Institute of Genetics, Mishima, Shizuoka 411 8540, Japan
    BMC Genomics 10:477. 2009
    ..Although conventional methods for BAC transgenesis have been very fruitful, complementary methods for generating single copy BAC integrations would be desirable for many applications...
  20. pmc Web API for biology with a workflow navigation system
    Yeondae Kwon
    Laboratory for Research and Development of Biological Databases, Center for Information Biology and DNA Data Bank of Japan, National Institute of Genetics, Yata 1111, Mishima, Shizuoka 411 8540, Japan
    Nucleic Acids Res 37:W11-6. 2009
    ..WABI and the workflow navigation system are freely accessible at http://www.xml.nig.ac.jp/index.html and http://cyclamen.ddbj.nig.ac.jp/, respectively...
  21. doi Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes
    Toshiaki Watanabe
    Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Research Organization of Information and Systems, Mishima 411 8540, Japan
    Nature 453:539-43. 2008
    ..Our results reveal a role for endogenous siRNAs in mammalian oocytes and show that organisms lacking RdRP activity can produce functional endogenous siRNAs from naturally occurring dsRNAs...
  22. pmc Evolution and control of imprinted FWA genes in the genus Arabidopsis
    Ryo Fujimoto
    Department of Integrated Genetics, National Institute of Genetics, Mishima, Shizuoka, Japan
    PLoS Genet 4:e1000048. 2008
    ..The possible significance of epigenetic variation in reproductive strategies during evolution is also discussed...
  23. doi Highly inclined thin illumination enables clear single-molecule imaging in cells
    Makio Tokunaga
    Biological Macromolecules Laboratory, National Institute of Genetics, Yata 1111, Mishima, Shizuoka 411 8540, Japan
    Nat Methods 5:159-61. 2008
    ..A high ratio yielded clear single-molecule images and three-dimensional images using cultured mammalian cells, enabling one to visualize and quantify molecular dynamics, interactions and kinetics in cells for molecular systems biology...
  24. ncbi The C. elegans CBFbeta homologue BRO-1 interacts with the Runx factor, RNT-1, to promote stem cell proliferation and self-renewal
    Hiroshi Kagoshima
    Genome Biology Laboratory, National Institute of Genetics, Mishima 411 8560, Japan
    Development 134:3905-15. 2007
    ..These studies provide new insights into the function and regulation of this important cancer-associated DNA-binding complex in stem cells and support the view that Runx/CBFbeta factors have oncogenic potential...
  25. ncbi Reproductive barrier and genomic imprinting in the endosperm of flowering plants
    Tetsu Kinoshita
    Integrated Genetics, National Institute of Genetics, Mishima, Japan
    Genes Genet Syst 82:177-86. 2007
    ..These predicted molecular mechanisms might be related to earlier models such as the "endosperm balance number" (EBN) and "polar nuclei activation" (PNA) hypotheses...
  26. pmc Natural variation of ebony gene controlling thoracic pigmentation in Drosophila melanogaster
    Aya Takahashi
    Division of Population Genetics, National Institute of Genetics, Mishima 411 8540, Japan
    Genetics 177:1233-7. 2007
    ..It was found to be the difference in expression level of ebony, which codes for an enzyme in the melanin-synthesis pathway and has pleiotropic effects on vision and behavior...
  27. ncbi [How do neurons establish and maintain their dendritic fields?]
    Kazuo Emoto
    Tanpakushitsu Kakusan Koso 52:842-52. 2007
  28. ncbi The aboral pore of hydra: evidence that the digestive tract of hydra is a tube not a sac
    Hiroshi Shimizu
    Department of Developmental Genetics, National Institute of Genetics, 1111 Yata, Mishima 411 8540, Japan
    Dev Genes Evol 217:563-8. 2007
    ..From these observations, we conclude that the digestive tract and the body plan of hydra is not a blind sac as formerly believed but is a tube with a tapered end...
  29. ncbi RUNX regulates stem cell proliferation and differentiation: insights from studies of C. elegans
    Hiroshi Kagoshima
    Genome Biology Laboratory, National Institute of Genetics, Mishima, Shizuoka, Japan
    J Cell Biochem 100:1119-30. 2007
    ..In this review, we will outline these new findings and discuss their general implications in the mechanism of coordination between proliferation and differentiation of stem cells...
  30. ncbi Tsix defective in splicing is competent to establish Xist silencing
    Takashi Sado
    Division of Human Genetics, National Institute of Genetics, Research Organization of Information and Systems, 1111 Yata, Mishima, 411 8540, Japan
    Development 133:4925-31. 2006
    ..Moreover, the repressive chromatin configuration was properly established at the Xist locus. These unexpected results indicate that the splicing products are dispensable for Tsix-mediated Xist silencing...
  31. ncbi De novo DNA methylation is dispensable for the initiation and propagation of X chromosome inactivation
    Takashi Sado
    Division of Human Genetics, National Institute of Genetics, 1111 Yata, Mishima 411 8540, Japan
    Development 131:975-82. 2004
    ..We also demonstrate that delayed upregulation of Xist does not induce X-inactivation, consistent with a crucial developmental window for the chromosomal silencing...
  32. ncbi The roles of ubiquitin and lipids in protein sorting along the endocytic pathway
    Kyohei Umebayashi
    Department of Cell Genetics, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411 8540, Japan
    Cell Struct Funct 28:443-53. 2003
    ..Ubiquitin and cholesterol hold the key to control the endocytic sorting, and they are likely acting cooperatively...
  33. ncbi Local changes in GC/AT substitution biases and in crossover frequencies on Drosophila chromosomes
    T Takano-Shimizu
    Department of Population Genetics, National Institute of Genetics, Mishima, Shizuoka ken, Japan
    Mol Biol Evol 18:606-19. 2001
    ..melanogaster after the melanogaster-yakuba divergence but before the melanogaster-simulans divergence...
  34. pmc DNA data bank of Japan (DDBJ) in collaboration with mass sequencing teams
    Y Tateno
    Center for Information Biology, National Institute of Genetics, Yata, Mishima 411 8540, Japan
    Nucleic Acids Res 28:24-6. 2000
    ..To cope with this situation, we have developed tools not only for processing such massive amounts of data but also for efficiently retrieving data on demand...
  35. ncbi Extensive nucleotide variability within a 370 kb sequence from the central region of the major histocompatibility complex
    S Gaudieri
    Centre for Information Biology, National Institute of Genetics, Mishima, Shizuoka, Japan
    Gene 238:157-61. 1999
    ..distinct troughs and peaks in the level of nucleotide variability. We will discuss these observations in relation to a possible role of nucleotide variability in the organisation of the MHC...
  36. ncbi Reproductive and genetic evidence for a reticulate evolutionary history of mass-spawning corals
    M Hatta
    National Institute of Genetics, Mishima, Japan
    Mol Biol Evol 16:1607-13. 1999
    ..These reproductive and genetic characteristics are consistent with a species complex formed under the separation/fusion processes predicted for a reticulate evolutionary history...
  37. ncbi Interplay of Notch and FGF signaling restricts cell fate and MAPK activation in the Drosophila trachea
    T Ikeya
    Genetic Strains Research Center and The Graduate University for Advanced Studies, National Institute of Genetics, Mishima 411 8540, Japan
    Development 126:4455-63. 1999
    ..Notch-mediated lateral inhibition in sending and receiving cells is thus essential to restrict the inductive influence of Branchless on the tracheal tubulogenesis...
  38. pmc Feasibility in the inverse protein folding protocol
    M Ota
    National Institute of Genetics, Mishima, Shizuoka, Japan
    Protein Sci 8:1001-9. 1999
    ..Namely, the inverse-folding search works significantly better with the score given by the 3D-1D alignment per se, rather than that obtained by the re-mounting. The implications of these results are discussed...
  39. ncbi Modulation of the nucleoid, the transcription apparatus, and the translation machinery in bacteria for stationary phase survival
    A Ishihama
    National Institute of Genetics, Department of Molecular Genetics, Mishima, Shizuoka 411 8540, Japan
    Genes Cells 4:135-43. 1999
    ..A small stationary-phase protein, RMF (Ribosome Modulation Factor), is involved in the dimerization of 70S ribosome monomers...
  40. ncbi Kinase-independent activity of Cdc2/cyclin A prevents the S phase in the Drosophila cell cycle
    S Hayashi
    National Institute of Genetics and The Graduate School for Advanced Studies, 1111 Yata, Mishima, Shizuoka ken 411 8540, Japan
    Genes Cells 4:111-22. 1999
    ..Whether this is the sole mechanism of S phase inhibition by Cdc2 in higher metazoans is not known because the pleiotropic functions of this essential cell cycle regulator make genetic analysis difficult...
  41. ncbi Subunits of yeast RNA polymerases: structure and function
    A Ishihama
    Department of Molecular Genetics, National Institute of Genetics, Mishima, Shizuoka 411, Japan
    Curr Opin Microbiol 1:190-6. 1998
    ..These protein-protein interactions ultimately lead to control of the activity and specificity of the RNA polymerases...
  42. ncbi An essential function of Grr1 for the degradation of Cln2 is to act as a binding core that links Cln2 to Skp1
    T Kishi
    Laboratory of Mutagenesis, Department of Molecular Genetics, National Institute of Genetics, Mishima, Shizuoka ken 411 8540, Japan
    J Cell Sci 111:3655-61. 1998
    ..Furthermore, Skp1 associated in vivo with phosphorylated Cln2 in a Grr1-dependent manner. These data suggest that Grr1 is required for degradation of Cln2 through linking phosphorylated Cln2 to Skp1 in a SCFGrr1 complex...
  43. ncbi The meaning of near-neutrality at coding and non-coding regions
    T Ohta
    Department of Population Genetics, National Institute of Genetics, Mishima, Shizuoka ken, Japan
    Gene 205:261-7. 1997
    ..Weak selection at non-coding regions may come from chromosome organization, and may be regional in character, which differs from that at coding regions. The problem of genetic load is thought to disappear in these circumstances...
  44. ncbi Evolutionary motif and its biological and structural significance
    Y Tateno
    Center for Information Biology, National Institute of Genetics, Mishima, Japan
    J Mol Evol 44:S38-43. 1997
    ..We then discussed their biological and structural significance. We believe that we are now in a position to analyze DNA and protein not only in vivo and in vitro but also in silico...
  45. pmc Characterization of spirochetes isolated from ticks (Ixodes tanuki, Ixodes turdus, and Ixodes columnae) and comparison of the sequences with those of Borrelia burgdorferi sensu lato strains
    M Fukunaga
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Japan
    Appl Environ Microbiol 62:2338-44. 1996
    ..The results of 16S rRNA gene sequence comparison suggest that the strain Am501 from I. columnae is related to group Hk501, although its level of DNA relatedness is less than 70%...
  46. ncbi Desmutagenic and bio-antimutagenic activity of docosahexaenoic acid and eicosapentaenoic acid in cultured Chinese hamster V79 cells
    Y Kuroda
    National Institute of Genetics, Mishima, 411 8540, Shizuoka, Japan
    Mutat Res 497:123-30. 2001
    ....
  47. ncbi The human low affinity Fcgamma receptors IIa, IIb, and III bind IgG with fast kinetics and distinct thermodynamic properties
    K Maenaka
    Structural Biology Center, National Institute of Genetics, Mishima, Shizuoka 411 8540, Japan
    J Biol Chem 276:44898-904. 2001
    ..Although the structural bases for these differences remain to be determined, they suggest that the molecular events coupled to the binding differ among the low affinity FcgammaRs...
  48. ncbi Knowledge-based potential defined for a rotamer library to design protein sequences
    M Ota
    National Institute of Genetics, Mishima, Shizuoka 411 8540 The Institute of Physical and Chemical Research RIKEN, Wako, Saitama 351 0198, Japan
    Protein Eng 14:557-64. 2001
    ..This significant improvement is discussed in terms of the reference state for normalization and the crucial role of short-range repulsion to prohibit residue bumps...
  49. ncbi Maintaining youth in Drosophila neural progenitors
    Takako Isshiki
    Genetic Strains Research Center, National Institute of Genetics, Mishima, Shizuoka, Japan
    Cell Cycle 3:296-9. 2004
    ....
  50. ncbi Physical modeling of the cellular arrangement in C. elegans early embryo: effect of rounding and stiffening of the cells
    Atsushi Kajita
    Genome Biology Laboratory, National Institute of Genetics, 1111 Yata, Mishima 411 8540, Japan
    Genome Inform 13:224-32. 2002
    ..Since cells could be soft during the period between cell divisions, implementation of the new model resulted in cell shapes similar to real embryos. The nature of the model and its relationship to real embryos are discussed...
  51. ncbi Peduncle of Hydra and the heart of higher organisms share a common ancestral origin
    Hiroshi Shimizu
    Department of Developmental Genetics, National Institute of Genetics, Mishima, Japan
    Genesis 36:182-6. 2003
    ....
  52. ncbi Evolution by gene duplication revisited: differentiation of regulatory elements versus proteins
    Tomoko Ohta
    National Institute of Genetics, Mishima 411 8540, Japan
    Genetica 118:209-16. 2003
    ..It is pointed out that constraints coming from regulatory networks are most important for survival of duplicate genes, and that both drift and selection are at work in the process of acquisition of new gene expression and function...
  53. pmc AHMII: Agent to Help Microbial Information Integration
    Hideaki Sugawara
    Center for Information Biology and DDBJ, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411 8540, Japan
    Nucleic Acids Res 31:3727-8. 2003
    ..The search agent is named Agent to Help Microbial Information Integration (AHMII) and the URL address is http://www.wdcm.org/AHMII/ahmii.html...
  54. pmc Two ubiquitin-conjugating enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, have distinct functions for ubiquitination of mitotic cyclin
    Hiroaki Seino
    Division of Mutagenesis, National Institute of Genetics, Mishima, Shizuoka 411 8540, Japan
    Mol Cell Biol 23:3497-505. 2003
    ....
  55. ncbi Detection of Borrelia duttonii, a tick-borne relapsing fever agent in central Tanzania, within ticks by flagellin gene-based nested polymerase chain reaction
    M Fukunaga
    Laboratory of Molecular Microbiology, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Hiroshima, Japan
    Vector Borne Zoonotic Dis 1:331-8. 2001
    ..The PCR method described in this report appears to be a reliable tool for the detection of borreliae and epidemiological study of tick-borne relapsing fever...
  56. ncbi Epi-alleles in plants: inheritance of epigenetic information over generations
    Tetsuji Kakutani
    National Institute of Genetics, Mishima, Shizuoka, 411 8540 Japan
    Plant Cell Physiol 43:1106-11. 2002
    ..Machinery controlling the establishment of the epigenetic state and role of the epigenetic controls in plant development are also discussed...
  57. ncbi [Deposition with DNA Date Bank of Japan (DDBJ); its data format and tools for submitions]
    Miyazaki Satoru
    Tanpakushitsu Kakusan Koso 47:733-6. 2002
  58. ncbi Context-dependent utilization of Notch activity in Drosophila glial determination
    Yoshihiko Umesono
    Division of Developmental Genetics, National Institute of Genetics, Department of Genetics, Graduate University for Advanced Studies, Mishima, 411 8540, Japan
    Development 129:2391-9. 2002
    ..We present evidence that POU-domain protein Nubbin/PDM-1 is one of the factors that provide such context...
  59. pmc Identification of histone H4-like TAF in Schizosaccharomyces pombe as a protein that interacts with WD repeat-containing TAF
    Hiroshi Mitsuzawa
    Department of Molecular Genetics, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411 8540, Japan
    Nucleic Acids Res 30:1952-8. 2002
    ..These results indicate that the C-terminal region of spTAF72, which largely consists of WD repeats, interacts with spTAF50 in the TFIID and SAGA-like complexes, suggesting a role for the WD repeat domain in the interaction between TAFs...
  60. pmc Genome Information Broker (GIB): data retrieval and comparative analysis system for completed microbial genomes and more
    Masaki Fumoto
    Center for Information Biology and DNA Data Bank of Japan, National Institute of Genetics, Yata, Mishima 411 8540, Japan
    Nucleic Acids Res 30:66-8. 2002
    ..In order to handle such huge data, we have enhanced the GIB architecture by using XML, CORBA and distributed RDBs. We introduce the new GIB here. GIB is freely accessible at http://gib.genes.nig.ac.jp/...
  61. ncbi The making of the somite: molecular events in vertebrate segmentation
    Y Saga
    Division of Mammalian Development, National Institute of Genetics, Yata 1111, Mishima 411 8540, Japan
    Nat Rev Genet 2:835-45. 2001
    ....
  62. pmc mtDNA polymorphism in East Asian Populations, with special reference to the peopling of Japan
    S Horai
    Department of Human Genetics, National Institute of Genetics, Shizuoka, Japan
    Am J Hum Genet 59:579-90. 1996
    ..It is suggested that approximately 65% of the gene pool in mainland Japanese was derived from the continental gene flow after the Yayoi Age...

Research Grants4

  1. Genetic methods using the Tol2 transposable element
    Koichi Kawakami; Fiscal Year: 2006
    ..abstract_text> ..