Hiroshi Yukawa

Summary

Affiliation: Nagoya University
Country: Japan

Publications

  1. doi request reprint Embryonic body formation using the tapered soft stencil for cluster culture device
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Graduate School of Medicine, Nagoya University, Higashi ku, Nagoya 461 0047, Japan
    Biomaterials 32:3729-38. 2011
  2. doi request reprint Monitoring transplanted adipose tissue-derived stem cells combined with heparin in the liver by fluorescence imaging using quantum dots
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Graduate School of Medicine, Nagoya University, Nagoya 461 0047, Japan
    Biomaterials 33:2177-86. 2012
  3. ncbi request reprint Direct cytotoxicity of Lentinula edodes mycelia extract on human hepatocellular carcinoma cell line
    Hiroshi Yukawa
    Department of New Product and Business Development, Central R and D Laboratory, Kobayashi Pharmaceutical Co, Ltd, Japan
    Biol Pharm Bull 35:1014-21. 2012
  4. ncbi request reprint Cell transplantation of adipose tissue-derived stem cells in combination with heparin attenuated acute liver failure in mice
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 461 0047, Japan
    Cell Transplant 18:611-8. 2009
  5. ncbi request reprint Comparison of sendai virus-mediated gene transfer efficiency to adhesive and floating adipose tissue-derived stem cells
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 461 0047, Japan
    Cell Transplant 18:601-9. 2009
  6. ncbi request reprint Quantum dots for labeling adipose tissue-derived stem cells
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 461 0047, Japan
    Cell Transplant 18:591-9. 2009
  7. ncbi request reprint Recombinant sendai virus-mediated gene transfer to adipose tissue-derived stem cells (ASCs)
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 461 0047, Japan
    Cell Transplant 17:43-50. 2008
  8. doi request reprint Quantum dots labeling using octa-arginine peptides for imaging of adipose tissue-derived stem cells
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya University, Higashi ku, Nagoya, Japan
    Biomaterials 31:4094-103. 2010
  9. ncbi request reprint Recombinant sendai virus-mediated gene transfer to mouse pancreatic stem cells
    Koichi Oishi
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Cell Transplant 18:573-80. 2009
  10. doi request reprint Efficient transfection of sendai virus vector to mouse pancreatic stem cells in the floating state
    Koichi Oishi
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Cell Transplant 19:893-900. 2010

Collaborators

Detail Information

Publications24

  1. doi request reprint Embryonic body formation using the tapered soft stencil for cluster culture device
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Graduate School of Medicine, Nagoya University, Higashi ku, Nagoya 461 0047, Japan
    Biomaterials 32:3729-38. 2011
    ..In conclusion, it appears that the TASCL device can be utilized for EB formation to generate cells for regenerative medicine applications...
  2. doi request reprint Monitoring transplanted adipose tissue-derived stem cells combined with heparin in the liver by fluorescence imaging using quantum dots
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Graduate School of Medicine, Nagoya University, Nagoya 461 0047, Japan
    Biomaterials 33:2177-86. 2012
    ..We suggest that fluorescence imaging by means of QDs labeling using R8 can be useful for tracing the transplanted cells...
  3. ncbi request reprint Direct cytotoxicity of Lentinula edodes mycelia extract on human hepatocellular carcinoma cell line
    Hiroshi Yukawa
    Department of New Product and Business Development, Central R and D Laboratory, Kobayashi Pharmaceutical Co, Ltd, Japan
    Biol Pharm Bull 35:1014-21. 2012
    ..In conclusion, LEP can directly induce apoptosis of HepG2 cells, and thus may have potential chemotherapeutic applications for the treatment of HCC...
  4. ncbi request reprint Cell transplantation of adipose tissue-derived stem cells in combination with heparin attenuated acute liver failure in mice
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 461 0047, Japan
    Cell Transplant 18:611-8. 2009
    ..In addition, all mice survived for at least the duration of the study period. In conclusion, the transplantation of ASCs in combination with heparin was thus found to effectively treat acute liver failure...
  5. ncbi request reprint Comparison of sendai virus-mediated gene transfer efficiency to adhesive and floating adipose tissue-derived stem cells
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 461 0047, Japan
    Cell Transplant 18:601-9. 2009
    ..These data suggest that SeV transfection to ASCs in the floating state could therefore be useful for gene transfer technology...
  6. ncbi request reprint Quantum dots for labeling adipose tissue-derived stem cells
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 461 0047, Japan
    Cell Transplant 18:591-9. 2009
    ..These data suggest that QDs could be utilized for the labeling of ASCs...
  7. ncbi request reprint Recombinant sendai virus-mediated gene transfer to adipose tissue-derived stem cells (ASCs)
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 461 0047, Japan
    Cell Transplant 17:43-50. 2008
    ..In conclusion, this is the first report describing the successful use of SeV-mediated gene transfer in ASCs, and the results indicate that SeV may thus provide advantages with respect to safety issues in gene therapy...
  8. doi request reprint Quantum dots labeling using octa-arginine peptides for imaging of adipose tissue-derived stem cells
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya University, Higashi ku, Nagoya, Japan
    Biomaterials 31:4094-103. 2010
    ..The labeled ASCs could be imaged with good contrast using the Maestro in vivo imaging system. These data suggested that QD labeling using R8 could be utilized for the imaging of ASCs...
  9. ncbi request reprint Recombinant sendai virus-mediated gene transfer to mouse pancreatic stem cells
    Koichi Oishi
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Cell Transplant 18:573-80. 2009
    ..In addition, pancreatic stem cells transfected with SeV maintained their differentiation ability. These data suggest that SeV could provide advantages with respect to safety issues in gene-modified regenerative medicine...
  10. doi request reprint Efficient transfection of sendai virus vector to mouse pancreatic stem cells in the floating state
    Koichi Oishi
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Cell Transplant 19:893-900. 2010
    ..These data suggest that SeV transfection to pancreatic stem cells in the floating state may be useful in gene transfer technology...
  11. doi request reprint Cryopreservation of human adipose tissue-derived stem/progenitor cells using the silk protein sericin
    Yoshitaka Miyamoto
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Higashi ku, Nagoya, Japan
    Cell Transplant 21:617-22. 2012
    ..This serum-free cryopreservation medium should be widely used in regenerative medicine, cell transplantation, and biological research...
  12. doi request reprint Estimation of the distribution of intravenously injected adipose tissue-derived stem cells labeled with quantum dots in mice organs through the determination of their metallic components by ICPMS
    Yuka Takasaki
    Division of Nano materials Science, EcoTopia Science Institute, Nagoya University, Furo cho, Chikusa ku, Nagoya, Japan
    Anal Chem 83:8252-8. 2011
    ..As a result of the calculation, 36.8%, 19.1%, 0.59%, 0.49%, and 0.25% of the total ASCs injected were estimated to be distributed in the liver, lung, heart, spleen, and kidney, respectively...
  13. ncbi request reprint Cryopreservation of mouse adipose tissue-derived stem/progenitor cells
    Koichi Oishi
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Cell Transplant 17:35-41. 2008
    ..These data suggests that Cell Banker 2 is the most effective cryopreservation solution for ASCs and that cryopreserved as well as noncryopreserved ASCs could be applied for regenerative medicine...
  14. pmc Novel Positive-Charged Nanoparticles for Efficient Magnetic Resonance Imaging of Islet Transplantation
    Koichi Oishi
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Cell Med 3:43-49. 2012
    ..These data suggest that novel positive-charged nanoparticles could be useful MRI contrast agents to monitor islet mass after transplantation...
  15. ncbi request reprint Differential ability of somatic stem cells
    Koichi Oishi
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Cell Transplant 18:581-9. 2009
    ..These data suggest that it is not easy for somatic stem cells to transdifferentiate into other germ cell types, at least, under these conditions...
  16. pmc Differentiation of Mouse Pancreatic Stem Cells Into Insulin-Producing Cells by Recombinant Sendai Virus-Mediated Gene Transfer Technology
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Higashi ku, Nagoya, Japan FIRST Research Center for Innovative Nanobiodevices, Nagoya University, Furo cho, Chikusa ku, Nagoya, Japan
    Cell Med 3:51-61. 2012
    ..These data suggest that the transduction of transcription factors using SeV vectors facilitates mPSC differentiation into insulin-producing cells and showed the possibility of regenerating β-cells by using transduced PSCs...
  17. pmc Novel positively charged nanoparticle labeling for in vivo imaging of adipose tissue-derived stem cells
    Hiroshi Yukawa
    Research Center for Innovative Nanobiodevices, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8603, Japan
    PLoS ONE 9:e110142. 2014
    ..The labeled ASCs could be imaged with good contrast using a 1T MR imaging system. These data suggest that TMADM-03 can therefore be utilized as a contrast agent for the MR imaging of stem cells. ..
  18. doi request reprint Transduction of cell-penetrating peptides into induced pluripotent stem cells
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Cell Transplant 19:901-9. 2010
    ..In conclusion, CPPs can be utilized for their differentiation or functional application in iPS cells...
  19. pmc Cryopreservation of Induced Pluripotent Stem Cells
    Yoshitaka Miyamoto
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Higashi ku, Nagoya, Japan Department of Oral Disease Research, National Center for Geriatrics and Gerontology, Aichi, Japan Clinical Research Center, National Center for Child Health and Development, Tokyo, Japan
    Cell Med 3:89-95. 2012
    ..The formation of teratomas was also examined. In conclusion, Cell Banker 3 allows for freezing of iPS cells in suspension...
  20. pmc Labeling and in vivo visualization of transplanted adipose tissue-derived stem cells with safe cadmium-free aqueous ZnS coating of ZnS-AgInS2 nanoparticles
    Yusuke Ogihara
    Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8603, Japan
    Sci Rep 7:40047. 2017
    ..In addition, high-speed multiphoton confocal laser microscopy revealed the presence of aggregates of transplanted ASCs at many sites in the lungs, whereas individual ASCs were found to have accumulated in the liver...
  21. doi request reprint Cell labeling with a novel contrast agent of magnetic resonance imaging
    Koichi Oishi
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Cell Transplant 19:887-92. 2010
    ..Therefore, TMADM-02 may have led to a false-positive test result. In future studies, we should verify not only the efficiency of labeling cells but also the stability of the contrast agent of MRI for clinical applications...
  22. doi request reprint Multifunctional quantum dots-based cancer diagnostics and stem cell therapeutics for regenerative medicine
    Daisuke Onoshima
    Institute of Innovation for Future Society, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8603, Japan ImPACT Research Center for Advanced Nanobiodevices, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8603, Japan Electronic address
    Adv Drug Deliv Rev 95:2-14. 2015
    ..This review highlights the promising applications of multi-functionalized QDs as advanced nanosensors for diagnosing cancer and as innovative fluorescence probes for in vitro or in vivo stem cell imaging in regenerative medicine. ..
  23. doi request reprint Microfluidic transfer of liquid interface for parallel stretching and stamping of terminal-unmodified single DNA molecules in zigzag-shaped microgrooves
    Hirotoshi Yasaki
    Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8603, Japan
    Lab Chip 15:135-40. 2015
    ..The stretched DNA molecules could be stamped to a silanized surface. The device will therefore serve as a template preparation for high-resolution DNA imaging studies. ..
  24. doi request reprint Crystal phase-controlled synthesis of rod-shaped AgInTe2 nanocrystals for in vivo imaging in the near-infrared wavelength region
    Tatsuya Kameyama
    Graduate School of Engineering, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8603, Japan
    Nanoscale 8:5435-40. 2016
    ....