Eiji Shibata

Summary

Affiliation: Nagoya University
Country: Japan

Publications

  1. ncbi request reprint Changes in n-hexane toxicokinetics in short-term single exposure due to co-exposure to methyl ethyl ketone in volunteers
    Eiji Shibata
    Department of Medical Technology, Nagoya University School of Health Sciences, 1 1 20 Daiko Minami, Higashi ku, Nagoya, 461 8673 Japan
    Int Arch Occup Environ Health 75:399-405. 2002
  2. doi request reprint Urinary concentrations of organophosphorus insecticide metabolites in Japanese workers
    Jun Ueyama
    Department of Medical Technology, Nagoya University School of Health Sciences, Nagoya 461 8673, Japan
    Chemosphere 87:1403-9. 2012
  3. doi request reprint Comparison of urinary concentrations of 3-phenoxybenzoic acid among general residents in rural and suburban areas and employees of pest control firms
    Akiko Kimata
    Program in Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Higashi ku, Nagoya, Japan
    Int Arch Occup Environ Health 82:1173-8. 2009
  4. doi request reprint Revised method for routine determination of urinary dialkyl phosphates using gas chromatography-mass spectrometry
    Jun Ueyama
    Program in Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan
    J Chromatogr B Analyt Technol Biomed Life Sci 878:1257-63. 2010
  5. ncbi request reprint Trichloroethylene causes generalized hypersensitivity skin disorders complicated by hepatitis
    Michihiro Kamijima
    Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Japan
    J Occup Health 50:328-38. 2008
  6. ncbi request reprint Biochemical changes in the central nervous system of rats exposed to 1-bromopropane for seven days
    Hailan Wang
    Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Toxicol Sci 67:114-20. 2002
  7. pmc Neurologic abnormalities in workers of a 1-bromopropane factory
    Gaku Ichihara
    Field of Social Life Science, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Environ Health Perspect 112:1319-25. 2004
  8. ncbi request reprint A survey of semen indices in insecticide sprayers
    Michihiro Kamijima
    Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    J Occup Health 46:109-18. 2004
  9. ncbi request reprint A sensitive colorimetric assay for polyamines in erythrocytes using oat seedling polyamine oxidase
    Kenji Takagi
    Department of Medical Technology, Nagoya University School of Health Sciences, 1 1 20 Daikominami, Nagoya 461 8673, Higashi, Japan
    Clin Chim Acta 340:219-27. 2004
  10. ncbi request reprint A survey on exposure level, health status, and biomarkers in workers exposed to 1-bromopropane
    Gaku Ichihara
    Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Am J Ind Med 45:63-75. 2004

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Changes in n-hexane toxicokinetics in short-term single exposure due to co-exposure to methyl ethyl ketone in volunteers
    Eiji Shibata
    Department of Medical Technology, Nagoya University School of Health Sciences, 1 1 20 Daiko Minami, Higashi ku, Nagoya, 461 8673 Japan
    Int Arch Occup Environ Health 75:399-405. 2002
    ..The aim of the present study was to describe the influence of co-exposure to MEK on n-hexane toxicokinetics in humans...
  2. doi request reprint Urinary concentrations of organophosphorus insecticide metabolites in Japanese workers
    Jun Ueyama
    Department of Medical Technology, Nagoya University School of Health Sciences, Nagoya 461 8673, Japan
    Chemosphere 87:1403-9. 2012
    ..These DAP concentrations were approximately the same or at lower levels compared with those reported in the previous literature. This is one of the first studies to demonstrate urinary DAP concentrations in Japanese adults...
  3. doi request reprint Comparison of urinary concentrations of 3-phenoxybenzoic acid among general residents in rural and suburban areas and employees of pest control firms
    Akiko Kimata
    Program in Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Higashi ku, Nagoya, Japan
    Int Arch Occup Environ Health 82:1173-8. 2009
    ....
  4. doi request reprint Revised method for routine determination of urinary dialkyl phosphates using gas chromatography-mass spectrometry
    Jun Ueyama
    Program in Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan
    J Chromatogr B Analyt Technol Biomed Life Sci 878:1257-63. 2010
    ..Compared to our previous method, the revised method underscores the importance of adding pre-derivatization anhydration for higher sensitivity and precision...
  5. ncbi request reprint Trichloroethylene causes generalized hypersensitivity skin disorders complicated by hepatitis
    Michihiro Kamijima
    Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Japan
    J Occup Health 50:328-38. 2008
    ..Since the lowest TCA concentration in the end-of-shift urine of the patients was estimated to be 72-80 mg/l, it is recommended to control TCE exposure to keep the urinary TCA concentration below 50 mg/l to reduce the disease risk...
  6. ncbi request reprint Biochemical changes in the central nervous system of rats exposed to 1-bromopropane for seven days
    Hailan Wang
    Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Toxicol Sci 67:114-20. 2002
    ..Glutathione depletion or modification to functional proteins containing a sulfhydryl base as a critical site might be the underlying mechanism of 1-bromopropane neurotoxicity...
  7. pmc Neurologic abnormalities in workers of a 1-bromopropane factory
    Gaku Ichihara
    Field of Social Life Science, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Environ Health Perspect 112:1319-25. 2004
    ..Time-weighted average exposure levels in the workers were 0.34-49.19 ppm. Exposure to 1-BP could adversely affect peripheral nerves or/and the central nervous system...
  8. ncbi request reprint A survey of semen indices in insecticide sprayers
    Michihiro Kamijima
    Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    J Occup Health 46:109-18. 2004
    ..Despite possible inherent differences between the groups, the above season-dependent differences suggested that the observed lower semen quality in the sprayers was associated with pesticide spraying work...
  9. ncbi request reprint A sensitive colorimetric assay for polyamines in erythrocytes using oat seedling polyamine oxidase
    Kenji Takagi
    Department of Medical Technology, Nagoya University School of Health Sciences, 1 1 20 Daikominami, Nagoya 461 8673, Higashi, Japan
    Clin Chim Acta 340:219-27. 2004
    ..The method is based on the unique substrate specificity of OSPO, which is active toward Spd and Spm, but not toward diamines such as Put and cadaverine and monoamines such as histamine...
  10. ncbi request reprint A survey on exposure level, health status, and biomarkers in workers exposed to 1-bromopropane
    Gaku Ichihara
    Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Am J Ind Med 45:63-75. 2004
    ..The aim of this study was to evaluate the health effects of exposure mainly to 1-bromopropane, which is an alternative to ozone-depleting solvents, and to establish biomarkers for assessing 1-bromopropane exposure...
  11. doi request reprint Beta-glucuronidase activity is a sensitive biomarker to assess low-level organophosphorus insecticide exposure
    Jun Ueyama
    Department of Medical Technology, Nagoya University School of Health Sciences, Higashi ku, Nagoya, Japan
    Toxicol Lett 193:115-9. 2010
    ..038 for difference, P=0.026 for trend). It was concluded that plasma BG activity is more sensitive biomarker as well as urinary OP metabolites than BChE for low-level exposure in humans...
  12. ncbi request reprint Involvement of caspase 3 mediated apoptosis in hematopoietic cytotoxicity of metabolites of ethylene glycol monomethyl ether
    Akira Takagi
    Department of Medical Technology, Nagoya University School of Health Sciences, Daiko minami 1 1 20, Higashi ku, Nagoya 461 8673, Japan
    Ind Health 40:371-4. 2002
    ..Caspase-3 enzyme activity, the effector of the apoptotic process, was greatly enhanced with MALD treatment. The inhibitor of caspase-3 repressed cell death induced with MALD as well as MAA...
  13. ncbi request reprint [Stevens-Johnson syndrome accompanied by acute hepatitis in workers exposed to trichloroethylene or tetrachloroethylene]
    Naomi Hisanaga
    National Institute of Industrial Health, 6 21 1, Nagao, Tama ku, Kawasaki 214 8585, Japan
    Sangyo Eiseigaku Zasshi 44:33-49. 2002
    ..Thirdly, the mechanism of the health disorder and the reason why there seems to be a large inter-individual difference in sensitivity to the causative agent should be clarified...
  14. ncbi request reprint Biological monitoring of pyrethroid exposure of pest control workers in Japan
    Dong Wang
    Department of Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Japan
    J Occup Health 49:509-14. 2007
    ..Further research should be accumulated to establish an occupational reference value in Japan...
  15. ncbi request reprint Overtime, job stressors, sleep/rest, and fatigue of Japanese workers in a company
    Takeshi Sasaki
    National Institute of Occupational Safety and Health, Kawasaki, Japan
    Ind Health 45:237-46. 2007
    ..318 and -0.340 in the 1st and 2nd surveys) and with monthly days off (r(s)=-0.250 and -0.151) among all of the subjects. It may be possible to assess overwork by the accumulated fatigue parameter...
  16. ncbi request reprint Simultaneous determination of urinary dialkylphosphate metabolites of organophosphorus pesticides using gas chromatography-mass spectrometry
    Jun Ueyama
    Department of Clinical Laboratory, Nagoya University Hospital, Nagoya 466 8560, Japan
    J Chromatogr B Analyt Technol Biomed Life Sci 832:58-66. 2006
    ..The present method, which does not require special equipment except for GC-MS, is quick, safe, and sensitive enough to be adopted in routine biological monitoring of non-occupational as well as occupational exposure to OPs...
  17. ncbi request reprint Asbestos exposures during reprocessing of automobile brakes and clutches
    Kiyoshi Sakai
    Nagoya City Public Health Research Institute, Nagoya, Japan
    Int J Occup Environ Health 12:95-105. 2006
    ..484 fibers/cm3 and 0.382 fibers/cm3, respectively. Machine grinding and leveling of new brake-lining surfaces represent potential sources of heavy asbestos exposures, unless enclosures and local ventilation are efficient...
  18. ncbi request reprint A comprehensive evaluation of the testicular toxicity of dichlorvos in Wistar rats
    Ai Okamura
    Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Toxicology 213:129-37. 2005
    ..This conclusion was also supported by an estimate of the decrease in human sperm motility based on the urinary DMP concentrations observed in actual occupational settings...
  19. ncbi request reprint Uptake and disposition of inhaled methanol vapor in humans
    Lena Ernstgård
    Work Environment Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Toxicol Sci 88:30-8. 2005
    ..Thus, apart from blood and urine, saliva also seems suitable for biomonitoring of methanol exposure...
  20. ncbi request reprint 8-Hydroxydeoxyguanosine levels in human leukocyte and urine according to exposure to organophosphorus pesticides and paraoxonase 1 genotype
    Chul Ho Lee
    Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, 65 Tsurumaicho, Showa Ku, Nagoya, Aichi 466 8550, Japan
    Int Arch Occup Environ Health 80:217-27. 2007
    ....
  21. ncbi request reprint Soluble fms-like tyrosine kinase 1 is increased in preeclampsia but not in normotensive pregnancies with small-for-gestational-age neonates: relationship to circulating placental growth factor
    Eiji Shibata
    Magee Womens Research Institute, University of Pittsburgh, 204 Craft Avenue, Pittsburgh, Pennsylvania 15213, USA
    J Clin Endocrinol Metab 90:4895-903. 2005
    ..However, the latter condition occurs without maternal vascular disease...
  22. ncbi request reprint Platelet factor 4 fragment induces histamine release from rat peritoneal mast cells
    Ryujiro Suzuki
    Laboratory Medicine, Nagoya University School of Medicine, Nagoya, Japan
    Peptides 23:1713-7. 2002
    ..Histamine release induced by PF-4 (58-70) occurred rapidly (<30s) and was inhibited by extracellular Ca(2+). These results suggest that PF-4 might play a crucial role at the site of inflammation and/or immune response...
  23. pmc Increased myeloperoxidase in the placenta and circulation of women with preeclampsia
    Robin E Gandley
    Magee Womens Research Institute, 204 Craft Ave, Pittsburgh, PA 15213, USA
    Hypertension 52:387-93. 2008
    ..We speculate that MPO may contribute to the oxidative damage reported in the endothelium and placenta of women with preeclampsia...
  24. ncbi request reprint A comparison of indoor air pollutants in Japan and Sweden: formaldehyde, nitrogen dioxide, and chlorinated volatile organic compounds
    Kiyoshi Sakai
    Nagoya City Public Health Research Institute, 1 11 Hagiyama cho, Mizuho ku, Nagoya 467 8615, Japan
    Environ Res 94:75-85. 2004
    ..More indoor pollution sources could be identified in Nagoya than in Uppsala, including construction and interior materials emitting VOC, use of unvented combustion space heaters, and moth repellents containing p-dichlorobenzene...
  25. ncbi request reprint [Indoor air pollution due to 2-ethyl-1-hexanol airborne concentrations, emission sources and subjective symptoms in classroom users]
    Michihiro Kamijima
    Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine
    Nihon Koshu Eisei Zasshi 52:1021-31. 2005
    ..This study aimed at clarifying changes in its concentration over time, emission sources, and students' symptoms in classrooms of a university building where indoor air was found to be markedly polluted with 2E1H...
  26. ncbi request reprint Indoor air pollution by 2-ethyl-1-hexanol in non-domestic buildings in Nagoya, Japan
    Kiyoshi Sakai
    Department of Environmental Health, Nagoya City Public Health Research Institute, 1 11 Hagiyama cho, Mizuho ku, Nagoya 467 8615, Japan
    J Environ Monit 8:1122-8. 2006
    ..Mechanical ventilation was effective in the temporary reduction of indoor 2-ethyl-1-hexanol level. These results suggest that the predominant source of 2-ethyl-1-hexanol was indoor areas...