Shuji Iritani

Summary

Affiliation: Nagoya University
Country: Japan

Publications

  1. pmc What happens in the brain of schizophrenia patients?: an investigation from the viewpoint of neuropathology
    Shuji Iritani
    Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 75:11-28. 2013
  2. doi request reprint Impact of dementia on cancer discovery and pain
    Shuji Iritani
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, Aichi, Japan
    Psychogeriatrics 11:6-13. 2011
  3. doi request reprint An atypical autopsy case of Lewy body disease with clinically diagnosed major depression: a clinical, radiological and pathological study
    Shuji Iritani
    Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Neuropathology 28:652-9. 2008
  4. doi request reprint Immunohistochemical study of vesicle monoamine transporter 2 in the hippocampal region of genetic animal model of schizophrenia
    Shuji Iritani
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa Ku, Nagoya, Aichi 466 8550, Japan
    Synapse 64:948-53. 2010
  5. doi request reprint Immunohistochemical study of vesicle monoamine transporter 2 in the hippocampal formation of PCP-treated mice
    Shuji Iritani
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa Ku, Nagoya, Aichi 466 8550, Japan
    Neurosci Res 68:125-30. 2010
  6. doi request reprint Clinicopathological study of diffuse neurofibrillary tangles with calcification. With special reference to TDP-43 proteinopathy and alpha-synucleinopathy
    Chikako Habuchi
    Department of Psychiatry, Nagoya University Graduate School of Medicine, Tsurumai cho, Showa Ku, Nagoya, Aichi ken 466 8550, Japan
    J Neurol Sci 301:77-85. 2011
  7. ncbi request reprint [Autopsy case of Lewy body dementia associated with abundant argyrophilic grains]
    Kenichi Oshima
    Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, 2 1 1 Kamikitazawa, Setagaya Ku, Tokyo 156 0057, Japan
    No To Shinkei 57:695-700. 2005
  8. doi request reprint Effects of aging on the morphologies of Heschl's gyrus and the superior temporal gyrus in schizophrenia: a postmortem study
    Youta Torii
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa Ku, Nagoya, Aichi 466 8550, Japan
    Schizophr Res 134:137-42. 2012
  9. doi request reprint An autopsy case of cortical superficial siderosis with persistent abnormal behavior
    Youta Torii
    Center for Postgraduate Clinical Training and Career Development, Nagoya University Hospital, Nagoya, Japan
    Neuropathology 36:544-550. 2016
  10. doi request reprint Immunohistochemical evaluation of the GABAergic neuronal system in the prefrontal cortex of a DISC1 knockout mouse model of schizophrenia
    Kentaro Umeda
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa Ku, Nagoya, Aichi, 466 8550, Japan
    Synapse 70:508-518. 2016

Detail Information

Publications31

  1. pmc What happens in the brain of schizophrenia patients?: an investigation from the viewpoint of neuropathology
    Shuji Iritani
    Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 75:11-28. 2013
    ..In that sense, neuropathological studies of this disease from new viewpoints have become essential...
  2. doi request reprint Impact of dementia on cancer discovery and pain
    Shuji Iritani
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, Aichi, Japan
    Psychogeriatrics 11:6-13. 2011
    ..The aim of the present study was to retrospectively evaluate how dementia modified the cancer discovery process, frequency of cancer pain reports and analgesic-narcotic use at a large psychiatric hospital...
  3. doi request reprint An atypical autopsy case of Lewy body disease with clinically diagnosed major depression: a clinical, radiological and pathological study
    Shuji Iritani
    Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Neuropathology 28:652-9. 2008
    ..Furthermore, it must be noted that some patients diagnosed with LLMD clinically may develop pathology of DLB without the typical or usual clinical symptoms...
  4. doi request reprint Immunohistochemical study of vesicle monoamine transporter 2 in the hippocampal region of genetic animal model of schizophrenia
    Shuji Iritani
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa Ku, Nagoya, Aichi 466 8550, Japan
    Synapse 64:948-53. 2010
    ..In conclusion, these findings might be related the pathophysiology of this disease includes a monoaminergic transmission abnormality, based on the investigation in a genetically-modified mouse as schizophrenic model...
  5. doi request reprint Immunohistochemical study of vesicle monoamine transporter 2 in the hippocampal formation of PCP-treated mice
    Shuji Iritani
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa Ku, Nagoya, Aichi 466 8550, Japan
    Neurosci Res 68:125-30. 2010
    ..Since insufficient or excess release of neurotransmitter might alter neurochemical function and neurotransmission, VMAT2 might be an important target for biological research in psychiatric disease including schizophrenia...
  6. doi request reprint Clinicopathological study of diffuse neurofibrillary tangles with calcification. With special reference to TDP-43 proteinopathy and alpha-synucleinopathy
    Chikako Habuchi
    Department of Psychiatry, Nagoya University Graduate School of Medicine, Tsurumai cho, Showa Ku, Nagoya, Aichi ken 466 8550, Japan
    J Neurol Sci 301:77-85. 2011
    ..These abnormal accumulations of TDP-43 might be involved in the pathological process of DNTC, having a close relationship to the FTLD-like psychiatric symptoms during the clinical course...
  7. ncbi request reprint [Autopsy case of Lewy body dementia associated with abundant argyrophilic grains]
    Kenichi Oshima
    Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, 2 1 1 Kamikitazawa, Setagaya Ku, Tokyo 156 0057, Japan
    No To Shinkei 57:695-700. 2005
    ..This report may contribute to the elucidation of the clinicopathological hallmarks of argyrophilic grain dementia and dementia with Lewy bodies...
  8. doi request reprint Effects of aging on the morphologies of Heschl's gyrus and the superior temporal gyrus in schizophrenia: a postmortem study
    Youta Torii
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa Ku, Nagoya, Aichi 466 8550, Japan
    Schizophr Res 134:137-42. 2012
    ..These findings indicate that the impact of aging has a greater effect on the WM in the STG in schizophrenic subjects than in normal individuals, although the pathological basis is still unclear...
  9. doi request reprint An autopsy case of cortical superficial siderosis with persistent abnormal behavior
    Youta Torii
    Center for Postgraduate Clinical Training and Career Development, Nagoya University Hospital, Nagoya, Japan
    Neuropathology 36:544-550. 2016
    ..Further clinicopathological studies are needed to clarify the clinical manifestations of patients with cSS...
  10. doi request reprint Immunohistochemical evaluation of the GABAergic neuronal system in the prefrontal cortex of a DISC1 knockout mouse model of schizophrenia
    Kentaro Umeda
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa Ku, Nagoya, Aichi, 466 8550, Japan
    Synapse 70:508-518. 2016
    ..These findings suggest that disrupted GABAergic neuronal network formation due to a DISC1 deficit might be involved in the pathophysiology of schizophrenia...
  11. doi request reprint Hypochondriasis as an early manifestation of dementia with Lewy bodies: an autopsied case report
    Hiroshige Fujishiro
    Department of Sleep Medicine, Graduate School of Medicine, Nagoya University, Nagoya, Japan
    Psychogeriatrics 16:139-44. 2016
    ..This autopsied case suggests that some DLB patients exhibit hypochondriasis in the early stage of the disease, even if they lack the core clinical features of DLB. ..
  12. doi request reprint Neuropeptide Y neuronal network dysfunction in the frontal lobe of a genetic mouse model of schizophrenia
    Shunsuke Morosawa
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa Ku, Nagoya, Aichi 466 8550, Japan Electronic address
    Neuropeptides . 2017
    ..DISC1 dysfunction may be involved in the pathogenesis of schizophrenia through the impairment of the NPY neuronal network...
  13. doi request reprint Presenile dementia diagnosed as posterior cortical atrophy
    Ayami Tsunoda
    Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    Psychogeriatrics 11:171-6. 2011
    ..The neuropathological background of PCA remains unclear. Therefore, the concept of PCA should be validated by the accumulation of information from more cases...
  14. ncbi request reprint [An autopsy case of senile dementia with pathological features of Parkinson's disease]
    Kenichi Oshima
    Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, 2 1 1 Kamikitazawa, Setagaya Ku, Tokyo 156 0057, Japan
    No To Shinkei 56:603-6. 2004
    ..That is, it is compatible with Parkinson's disease. We postulate that the clinical features of Parkinson's disease are more widespread than previously considered...
  15. doi request reprint Catecholaminergic neuronal network dysfunction in the frontal lobe of a genetic mouse model of schizophrenia
    Shuji Iritani
    1Department of Psychiatry, Graduate School of Medicine, Nagoya University, Showa Ku, Nagoya, Aichi, Japan
    Acta Neuropsychiatr 28:117-23. 2016
    ..The precise aetiology of schizophrenia remains unclear. The neurodevelopmental hypothesis of schizophrenia has been proposed based on the accumulation of genomic or neuroimaging studies...
  16. ncbi request reprint [An autopsy case of "progressive supranuclear palsy" without psychiatric or neurological signs]
    Kenichi Oshima
    Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, Department of Psychogeriatrics, Tokyo Institute of Psychiatry, Japan
    No To Shinkei 56:157-61. 2004
    ..Staining by Gallyas-Braak methods disclosed tuft-shaped astrocytes in the caudate nucleus, putamen, and thalamus. To our knowledge, this is the first report of "PSP" without psychiatric or neurological signs...
  17. doi request reprint Impairment of the tyrosine hydroxylase neuronal network in the orbitofrontal cortex of a genetically modified mouse model of schizophrenia
    Hirotaka Sekiguchi
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa Ku, Nagoya, Aichi 466 8550, Japan
    Brain Res 1392:47-53. 2011
    ..There is thought to be a dysfunction of a neurotransmitter such as dopamine and noradrenalin in the prefrontal cortex of these knockout mice...
  18. ncbi request reprint Immunohistochemical study of the serotonergic neuronal system in an animal model of the mood disorder
    Shuji Iritani
    Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466 8550, Japan
    Exp Neurol 201:60-5. 2006
    ..These alterations may underlie the changes of serotonergic system observed in the brains of patients with the depressive disorder...
  19. doi request reprint Rapid eye movement sleep without atonia may help diagnose Lewy body disease in middle-aged and older patients with somatic symptom disorder
    Takayuki Munechika
    Department of Psychiatry, Nagoya University School of Medicine, Nagoya, Japan
    Psychogeriatrics . 2016
    ..Given the close association between rapid eye movement (REM) sleep behaviour disorder and LBD, REM sleep without atonia on polysomnography may help to diagnose LBD in middle-aged and older patients with somatic symptom disorder...
  20. doi request reprint Autopsy-confirmed hippocampal-sparing Alzheimer's disease with delusional jealousy as initial manifestation
    Hiroshige Fujishiro
    Department of Sleep Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Psychogeriatrics 15:198-203. 2015
    ..Although the neural basis of delusional jealousy remains unclear, this hippocampal-sparing AD case may be classified as an atypical presentation of AD. ..
  21. ncbi request reprint [An autopsy case of argyrophilic grain dementia with abundant neurofibrillary tangles]
    Kenichi Oshima
    Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, Department of Psychogeriatrics, Tokyo Institute of Psychiatry, Tokyo, Japan
    No To Shinkei 55:133-8. 2003
    ..Sarkosyl-insoluble tau extracted from the temporal lobe consisted predominantly of four-repeat tau isoforms. To our knowledge, this is the first report of argyrophilic grain dementia complicated with tangle only dementia...
  22. doi request reprint REM sleep without atonia in middle-aged and older psychiatric patients and Lewy body disease: a case series
    Hiroshige Fujishiro
    Department of Sleep Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Int J Geriatr Psychiatry . 2016
    ..The purpose of this study is to investigate the clinical features of psychiatric patients exhibiting RWA and its relevance to Lewy body disease...
  23. ncbi request reprint The distribution of serotonin transporter immunoreactivity in hippocampal formation in monkeys and rats
    Toshimi Owashi
    Department of Psychiatry, Showa University School of Medicine, 1 5 8, Hatanodai, Shinagawa, Tokyo 142 8666, Japan
    Brain Res 1010:166-8. 2004
    ..However, in monkeys, punctuate 5-HTT-immunoreactive deposits and fewer fibers were observed. The species difference in 5-HTT immunohistochemical staining pattern may be caused by differences in localization of 5-HTT between species...
  24. ncbi request reprint Immunohistochemical study of brain-derived neurotrophic factor and its receptor, TrkB, in the hippocampal formation of schizophrenic brains
    Shuji Iritani
    Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, 2 1 1 Kamikitazawa, Setagaya, Tokyo 156 0057, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 27:801-7. 2003
    ....
  25. ncbi request reprint Delirium prior to dementia as a clinical phenotype of Lewy body disease: an autopsied case report
    Hiroshige Fujishiro
    Department of Sleep Medicine, Nagoya University School of Medicine, 65 Tsurumai, Showa Ku, Nagoya, Aichi, 466 8550, Japan
    Int Psychogeriatr . 2016
    ..She developed no core clinical features of DLB and died of pneumonia at the age of 90 years. This autopsied case suggests that delirium may be one of the clinical phenotypes of LBD prior to the onset of dementia...
  26. doi request reprint Effectiveness of low-dose milnacipran for a patient suffering from pain disorder with delusional disorder (somatic type) in the orofacial region
    Katsuyuki Ukai
    Kamiiida Daiichi General Hospital, 2 70 Kamiiida kitamachi, Kita ku, Nagoya, Japan
    Psychogeriatrics 13:99-102. 2013
    ..However, when sertraline was changed to milnacipran, all symptoms disappeared in a short period. We suggest that a small dose of milnacipran can be effective for controlling oral cenesthopathy as well as glossodynia. ..
  27. ncbi request reprint [Neuropathology of scizophrenia--from a new perspective]
    Shuji Iritani
    Department of Psychiatry, Nagoya University, Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Brain Nerve 59:605-16. 2007
    ..It is important to consider together these findings with morphometric studies in neuropathological observation, neuroimaging studies and genome studies to pursue the etiology of schizophrenia from various perspectives...
  28. ncbi request reprint Vascular complications in dementia with Lewy bodies: a postmortem study
    Daisuke Isojima
    Department of Psychiatry, School of Medicine, Yokohama City University, Japan
    Neuropathology 26:293-7. 2006
    ..Such vascular complications might affect the clinical manifestations, in particular, the initial symptom, of DLB...
  29. doi request reprint A case of dementia with Lewy bodies that temporarily showed symptoms similar to Creutzfeldt-Jakob disease
    Katsuyuki Ukai
    Kamiiida Daiichi General Hospital, Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Psychogeriatrics 10:201-5. 2010
    ..The present study describes a clinically atypical case with probable DLB and reviews similar cases in the literature, and we propose a rapidly progressive clinical subtype of DLB...
  30. doi request reprint The effects of acute treatment with ramelteon, triazolam, and placebo on driving performance, cognitive function, and equilibrium function in healthy volunteers
    Akemi Miyata
    Department of Psychiatry, Nagoya University, Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya, Aichi, 466 8550, Japan
    Psychopharmacology (Berl) 232:2127-37. 2015
    ..Hypnotics are widely used to treat insomnia but adverse effects of different hypnotics, especially benzodiazepine receptor agonists, are getting more attention lately. The effects of novel hypnotics have not been fully examined...
  31. ncbi request reprint Neuropathology of schizophrenia: a mini review
    Shuji Iritani
    Department of Psychiatry, Nagoya University, Graduate School of Medicine, Nagoya, Japan
    Neuropathology 27:604-8. 2007
    ..It is important to consider together these findings with morphometric studies in neuropathological observation, neuroimaging studies and genome studies to pursue the etiology of schizophrenia from various perspectives...