Akira Funada

Summary

Affiliation: Nagasaki University
Country: Japan

Publications

  1. doi request reprint Prognostic significance of late gadolinium enhancement quantification in cardiac magnetic resonance imaging of hypertrophic cardiomyopathy with systolic dysfunction
    Akira Funada
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 5 7 1 Fujishiro dai, Suita, Osaka, 565 8565, Japan
    Heart Vessels 31:758-70. 2016
  2. doi request reprint Late aneurysm formation of Valsalva sinus after aortic valve replacement due to Takayasu's arteritis
    Akira Funada
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 5 7 1 Fujishiro dai, Suita, 565 8565, Japan
    Heart Vessels 30:558-62. 2015
  3. ncbi request reprint Three cases of iatrogenic coronary ostial stenosis after aortic valve replacement
    Akira Funada
    Fukui Cardiovascular Center, Shinbo, Fukui, Japan
    Circ J 70:1312-7. 2006
  4. doi request reprint Assessment of QT intervals and prevalence of short QT syndrome in Japan
    Akira Funada
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    Clin Cardiol 31:270-4. 2008
  5. doi request reprint Long QT syndrome and associated gene mutation carriers in Japanese children: results from ECG screening examinations
    Kenshi Hayashi
    Kanazawa University Graduate School of Medical Science, Ishikawa, Japan
    Clin Sci (Lond) 117:415-24. 2009
  6. doi request reprint A KCR1 variant implicated in susceptibility to the long QT syndrome
    Kenshi Hayashi
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan
    J Mol Cell Cardiol 50:50-7. 2011
  7. doi request reprint Extent of heart rate reduction during hospitalization using beta-blockers, not the achieved heart rate itself at discharge, predicts the clinical outcome in patients with acute heart failure syndromes
    Hiroyuki Takahama
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita 565 8565, Osaka, Japan
    J Cardiol 61:58-64. 2013
  8. ncbi request reprint Differences in diagnostic value of four electrocardiographic voltage criteria for hypertrophic cardiomyopathy in a genotyped population
    Tetsuo Konno
    Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
    Am J Cardiol 96:1308-12. 2005
  9. doi request reprint Prognostic Impact of Functional Mitral Regurgitation in Patients Admitted With Acute Decompensated Heart Failure
    Yuko Wada
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
    Circ J 80:139-47. 2016
  10. ncbi request reprint A successful case of percutaneous transluminal septal myocardial ablation for mitral regurgitation that emerged following mitral valve repair surgery
    Tomohiro Hayashi
    Cardiovascular Division of Medicine, National Cerebral and Cardiovascular Center, Japan
    Intern Med 52:2765-9. 2013

Collaborators

Detail Information

Publications28

  1. doi request reprint Prognostic significance of late gadolinium enhancement quantification in cardiac magnetic resonance imaging of hypertrophic cardiomyopathy with systolic dysfunction
    Akira Funada
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 5 7 1 Fujishiro dai, Suita, Osaka, 565 8565, Japan
    Heart Vessels 31:758-70. 2016
    ..20 and 178.09, respectively).The extent of LGE was a good independent predictor of adverse cardiac events and reflected mortality and morbidity more precisely than LVEF in HCM with systolic dysfunction. ..
  2. doi request reprint Late aneurysm formation of Valsalva sinus after aortic valve replacement due to Takayasu's arteritis
    Akira Funada
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 5 7 1 Fujishiro dai, Suita, 565 8565, Japan
    Heart Vessels 30:558-62. 2015
    ..Close and lifelong follow-up for patients with TA regarding development of aneurysm after surgical treatment is indispensable when fragility of the aortic root had been confirmed. ..
  3. ncbi request reprint Three cases of iatrogenic coronary ostial stenosis after aortic valve replacement
    Akira Funada
    Fukui Cardiovascular Center, Shinbo, Fukui, Japan
    Circ J 70:1312-7. 2006
    ..Iatrogenic coronary ostial stenosis (ICOS) is a rare but potentially life-threatening complication of aortic valve replacement (AVR). This complication is usually diagnosed by angiography and treated with aortocoronary bypass surgery...
  4. doi request reprint Assessment of QT intervals and prevalence of short QT syndrome in Japan
    Akira Funada
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    Clin Cardiol 31:270-4. 2008
    ..Recently, a short QT interval has also been shown to be associated with an increased risk of tachyarrhythmia and sudden death. However, the prevalence of short QT syndrome is not well-known...
  5. doi request reprint Long QT syndrome and associated gene mutation carriers in Japanese children: results from ECG screening examinations
    Kenshi Hayashi
    Kanazawa University Graduate School of Medical Science, Ishikawa, Japan
    Clin Sci (Lond) 117:415-24. 2009
    ..038% (one in 2653). Furthermore, large-scale genetic studies will be needed to clarify the real prevalence of LQTS by gene-carrier status, as it may have been underestimated in the present study...
  6. doi request reprint A KCR1 variant implicated in susceptibility to the long QT syndrome
    Kenshi Hayashi
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan
    J Mol Cell Cardiol 50:50-7. 2011
    ..Our findings suggest that KCR1 genetic variations that diminish the ability of KCR1 to protect KCNH2 from inhibition by commonly used therapeutic agents constitute a risk factor for the aLQTS...
  7. doi request reprint Extent of heart rate reduction during hospitalization using beta-blockers, not the achieved heart rate itself at discharge, predicts the clinical outcome in patients with acute heart failure syndromes
    Hiroyuki Takahama
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita 565 8565, Osaka, Japan
    J Cardiol 61:58-64. 2013
    ..The present study investigated the influence of HRR during hospitalization on the prognosis of AHFS patients...
  8. ncbi request reprint Differences in diagnostic value of four electrocardiographic voltage criteria for hypertrophic cardiomyopathy in a genotyped population
    Tetsuo Konno
    Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
    Am J Cardiol 96:1308-12. 2005
    ..Therefore, understanding the diagnostic value of classic ECG voltage criteria may be important in detecting carriers, including those without left ventricular hypertrophy...
  9. doi request reprint Prognostic Impact of Functional Mitral Regurgitation in Patients Admitted With Acute Decompensated Heart Failure
    Yuko Wada
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
    Circ J 80:139-47. 2016
    ..It is unclear whether FMR on admission or discharge determines the outcome. This study aimed to elucidate the prognostic significance of FMR on admission or discharge in patients admitted with acute decompensated HF...
  10. ncbi request reprint A successful case of percutaneous transluminal septal myocardial ablation for mitral regurgitation that emerged following mitral valve repair surgery
    Tomohiro Hayashi
    Cardiovascular Division of Medicine, National Cerebral and Cardiovascular Center, Japan
    Intern Med 52:2765-9. 2013
    ..After the procedure, the MR resolved, with a reduced LVOT pressure gradient. The patient's symptoms improved. PTSMA was effective for the treatment of MR that emerged after mitral valve repair. ..
  11. doi request reprint The predictability of renin-angiotensin-aldosterone system factors for clinical outcome in patients with acute decompensated heart failure
    Yasuki Nakada
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, 565 8565, Japan
    Heart Vessels 31:925-31. 2016
    ..The measurements of RAAS factors help to stratify ADHF patients at risk for further CV events. ..
  12. doi request reprint Increased extent of myocardial fibrosis in genotyped hypertrophic cardiomyopathy with ventricular tachyarrhythmias
    Takashi Fujita
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
    J Cardiol 66:63-8. 2015
    ....
  13. doi request reprint Pathophysiological impact of serum fibroblast growth factor 23 in patients with nonischemic cardiac disease and early chronic kidney disease
    Miki Imazu
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan
    Am J Physiol Heart Circ Physiol 307:H1504-11. 2014
    ..001). These findings suggest that the progression of HF per se contributes to the elevation of sFGF23 levels even in the early stages of CKD, which leads to further myocardial dysfunction, potentially creating a vicious cycle. ..
  14. ncbi request reprint Images in cardiovascular medicine. Adult patient with isolated noncompaction of ventricular myocardium
    Tomoya Kaneda
    Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa 920 8640, Japan
    Circulation 112:e96-7. 2005
  15. doi request reprint Intracardiac echocardiography to diagnose pannus formation after aortic valve replacement
    Yoshiya Yamamoto
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 5 7 1 Fujishiro dai, Suita, Osaka, 565 8565, Japan
    J Echocardiogr 14:39-41. 2016
    ..Transesophageal echocardiogram also revealed this structure. ICE can visualize structural abnormalities around a prosthetic valve after cardiac surgery even in patients in whom conventional imaging modalities failed...
  16. doi request reprint Compound heterozygosity deteriorates phenotypes of hypertrophic cardiomyopathy with founder MYBPC3 mutation: evidence from patients and zebrafish models
    Akihiko Hodatsu
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan and
    Am J Physiol Heart Circ Physiol 307:H1594-604. 2014
    ..These results demonstrate that MYBPC3 Val762Asp may be associated with unfavorable HCM phenotypes in some cases when combined with another MYBPC3 mutation. ..
  17. ncbi request reprint Heterogeneity of clinical manifestation of hypertrophic cardiomyopathy caused by deletion of lysine 183 in cardiac troponin I gene
    Akira Funada
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Ishikawa, Japan
    Int Heart J 51:214-7. 2010
    ..The findings suggest that additional genetic or environmental factors influence the phenotypic expressions and clinical courses of HCM caused by genetic mutation of sarcomeric proteins...
  18. ncbi request reprint Impact of renin-angiotensin system polymorphisms on development of systolic dysfunction in hypertrophic cardiomyopathy. Evidence from a study of genotyped patients
    Akira Funada
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
    Circ J 74:2674-80. 2010
    ..The effect of RAS polymorphisms on LV function in genotyped hypertrophic cardiomyopathy (HCM) was examined in the present study...
  19. ncbi request reprint Gene mutations in adult Japanese patients with dilated cardiomyopathy
    Masami Shimizu
    Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Japan
    Circ J 69:150-3. 2005
    ..Some patients with dilated cardiomyopathy (DCM) have mutations of the genes that encode sarcomeric or cytoskeletal proteins of cardiomyocytes, but the prevalence of these mutations in Japan remains unclear...
  20. doi request reprint Age-specific differences in prognostic significance of rhythm conversion from initial non-shockable to shockable rhythm and subsequent shock delivery in out-of-hospital cardiac arrest
    Akira Funada
    Department of Emergency and Critical Care Medicine, Kanazawa University Hospital, Japan Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
    Resuscitation 108:61-67. 2016
    ....
  21. doi request reprint Extensive late gadolinium enhancement on cardiovascular magnetic resonance predicts adverse outcomes and lack of improvement in LV function after steroid therapy in cardiac sarcoidosis
    Takayuki Ise
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan
    Heart 100:1165-72. 2014
    ....
  22. doi request reprint Prehospital predictors of neurological outcomes in out-of-hospital cardiac arrest patients aged 95 years and older: A nationwide population-based observational study
    Akira Funada
    Department of Emergency and Critical Care Medicine, Kanazawa University Hospital, Kanazawa, Japan Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
    J Cardiol 69:340-344. 2017
    ..We aimed to determine the prehospital predictors of one-month survival with favorable neurological outcomes (Cerebral Performance Category scale, category 1 or 2; CPC 1-2) in this population...
  23. ncbi request reprint Differentiation between patients with takotsubo cardiomyopathy and those with anterior acute myocardial infarction
    Masaru Inoue
    Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
    Circ J 69:89-94. 2005
    ....
  24. pmc Subsequent Shockable Rhythm During Out-of-Hospital Cardiac Arrest in Children With Initial Non-Shockable Rhythms: A Nationwide Population-Based Observational Study
    Yoshikazu Goto
    Department of Emergency and Critical Care Medicine, Kanazawa University Hospital, Kanazawa, Japan
    J Am Heart Assoc 5:. 2016
    ..We hypothesized that subsequent treated shockable rhythm in children with out-of-hospital cardiac arrest would improve survival with favorable neurological outcomes (Cerebral Performance Category scale 1-2)...
  25. pmc Relationship Between the Duration of Cardiopulmonary Resuscitation and Favorable Neurological Outcomes After Out-of-Hospital Cardiac Arrest: A Prospective, Nationwide, Population-Based Cohort Study
    Yoshikazu Goto
    Department of Emergency and Critical Care Medicine, Kanazawa University Hospital, Kanazawa, Japan
    J Am Heart Assoc 5:e002819. 2016
    ..The appropriate CPR duration before termination of resuscitation remains unclear and may differ based on initial rhythm. We aimed to determine the relationship between CPR duration and post-OHCA outcomes...
  26. ncbi request reprint The incidence of stent-edge spasm after stent implantation in patients with or without vasospastic angina pectoris
    Bunji Kaku
    Department of Internal Medicine, Ishikawa Prefectural Central Hospital, Kanazawa, Japan
    Int Heart J 46:23-33. 2005
    ..7%). Moderate stent-edge spasm was provoked in 5 patients with VSA (19.2%) and 5 patients without VSA (21.7%). The results suggest new onset stent-edge spasm in patients either with or without VSA should not be neglected...
  27. ncbi request reprint Serum blood urea nitrogen and plasma brain natriuretic Peptide and low diastolic blood pressure predict cardiovascular morbidity and mortality following discharge in acute decompensated heart failure patients
    Chun Yen Chen
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 5 7 1 Fujishirodai, Suita 565 8565, Japan
    Circ J 76:2372-9. 2012
    ..The purpose of the present study was therefore to investigate predictors of CV death and re-hospitalization for acute decompensated HF (ADHF)...
  28. ncbi request reprint A case of the toxicity of pilsicainide hydrochloride with comparison of the serial serum pilsicainide levels and electrocardiographic findings
    Yuhki Horita
    Department of Cardiology, Ishikawa Prefectural Central Hospital, Ishikawa 920 8530, Japan
    Jpn Heart J 45:1049-56. 2004
    ..Estimation of the serum level may be possible from the electrocardiographic findings if the pilsicainide toxicity occurs...