H Mizutani

Summary

Affiliation: Mie University
Country: Japan

Publications

  1. ncbi request reprint Endogenous neutralizing anti-IL-1 alpha autoantibodies in inflammatory skin diseases: possible natural inhibitor for over expressed epidermal IL-1
    H Mizutani
    Department of Dermatology, Mie University School of Medicine, Japan
    J Dermatol Sci 20:63-71. 1998
  2. pmc Intranasally administered antigen 85B gene vaccine in non-replicating human Parainfluenza type 2 virus vector ameliorates mouse atopic dermatitis
    Hiroshi Kitagawa
    Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
    PLoS ONE 8:e66614. 2013
  3. doi request reprint Single step modified ink staining for Tzanck test: quick detection of herpetic giant cells in Tzanck smear
    Hitoshi Mizutani
    Departments of Dermatology Immunology, Graduate School of Medicine, Mie University, Tsu, Mie, Japan
    J Dermatol 39:138-40. 2012
  4. doi request reprint Heat-killed bacillus Calmette-Guérin and Mycobacterium kansasii antigen 85B combined vaccination ameliorates dermatitis in a mouse model of atopic dermatitis by inducing regulatory T cells
    M Kakeda
    Department of Dermatology Immunology, Mie University, Tsu, Mie, Japan
    Br J Dermatol 166:953-63. 2012
  5. doi request reprint IL-4/IL-13 antagonist DNA vaccination successfully suppresses Th2 type chronic dermatitis
    T Morioka
    Department of Dermatology, Mie University, Tsu, Japan
    Br J Dermatol 160:1172-9. 2009
  6. doi request reprint 1,24-Dihydroxyvitamin D₃ (tacalcitol) prevents skin T-cell infiltration
    K I Yamanaka
    Department of Dermatology Immunology, Mie University, Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Br J Dermatol 162:1206-15. 2010
  7. ncbi request reprint Cytokeratin expression in subungual squamous cell carcinoma
    I Kurokawa
    Department of Dermatology, Mie University Graduate School of Medicine, Mie, Japan
    J Int Med Res 34:441-3. 2006
  8. ncbi request reprint Topical suplatast tosilate (IPD) ameliorates Th2 cytokine-mediated dermatitis in caspase-1 transgenic mice by downregulating interleukin-4 and interleukin-5
    T Murakami
    Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie 514 8507, Japan
    Br J Dermatol 155:27-32. 2006
  9. ncbi request reprint Simultaneous development of two cases of eosinophilia-myalgia syndrome with the same lot of L-tryptophan in Japan
    T Mizutani
    Department of Dermatology, Mie University, School of Medicine, Japan
    J Am Acad Dermatol 25:512-7. 1991
  10. ncbi request reprint Keratinizing squamous epithelium associated with Syringocystadenoma papilliferum differentiates towards infrainfundibulum: case report with immunohistochemical study of cytokeratins
    I Kurokawa
    Department of Dermatology, Mie University Graduate School of Medicine, Edobashi, Tsu, Mie, Japan
    J Int Med Res 33:590-3. 2005

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Endogenous neutralizing anti-IL-1 alpha autoantibodies in inflammatory skin diseases: possible natural inhibitor for over expressed epidermal IL-1
    H Mizutani
    Department of Dermatology, Mie University School of Medicine, Japan
    J Dermatol Sci 20:63-71. 1998
    ..Taken together present data, the keratinocyte derived IL-1alpha could be a source of autoantigen that provokes production of endogenous anti-IL-1alpha autoantibody, which may regulate IL-1alpha mediated cutaneous inflammation...
  2. pmc Intranasally administered antigen 85B gene vaccine in non-replicating human Parainfluenza type 2 virus vector ameliorates mouse atopic dermatitis
    Hiroshi Kitagawa
    Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
    PLoS ONE 8:e66614. 2013
    ..The respiratory tract epithelium captured rhPIV2 effectively without remarkable cytotoxic effects. These results suggested that rhPIV2/Ag85B might be a potent therapeutic tool to control allergic disorders. ..
  3. doi request reprint Single step modified ink staining for Tzanck test: quick detection of herpetic giant cells in Tzanck smear
    Hitoshi Mizutani
    Departments of Dermatology Immunology, Graduate School of Medicine, Mie University, Tsu, Mie, Japan
    J Dermatol 39:138-40. 2012
    ..One step staining of Tzanck smear using this diluted ink solution is an inexpensive and a convenient bedside diagnostic tool for the dermatologist...
  4. doi request reprint Heat-killed bacillus Calmette-Guérin and Mycobacterium kansasii antigen 85B combined vaccination ameliorates dermatitis in a mouse model of atopic dermatitis by inducing regulatory T cells
    M Kakeda
    Department of Dermatology Immunology, Mie University, Tsu, Mie, Japan
    Br J Dermatol 166:953-63. 2012
    ..Bacillus Calmette-Guérin (BCG) has been used for preventing tuberculosis, and is regarded as a strong Th1 cytokine inducer. Antigen (Ag) 85B is a secretory protein present in Mycobacterium species that induces Th1 cytokine production...
  5. doi request reprint IL-4/IL-13 antagonist DNA vaccination successfully suppresses Th2 type chronic dermatitis
    T Morioka
    Department of Dermatology, Mie University, Tsu, Japan
    Br J Dermatol 160:1172-9. 2009
    ..We have recently developed a highly efficient mouse dominant negative interleukin (IL)-4/IL-13 antagonist (IL-4DM), which blocks both IL-4 and IL-13 signal transductions...
  6. doi request reprint 1,24-Dihydroxyvitamin D₃ (tacalcitol) prevents skin T-cell infiltration
    K I Yamanaka
    Department of Dermatology Immunology, Mie University, Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Br J Dermatol 162:1206-15. 2010
    ..We recently reported that 1,25-dihydroxyvitamin D₃ inhibits skin infiltration of CD4+ T cells by suppressing CLA expression on T cells...
  7. ncbi request reprint Cytokeratin expression in subungual squamous cell carcinoma
    I Kurokawa
    Department of Dermatology, Mie University Graduate School of Medicine, Mie, Japan
    J Int Med Res 34:441-3. 2006
    ..The tumour nests contained cytokeratin 14, 16 and 17, which were also expressed in the nail bed. Therefore, cytokeratin expression in subungual squamous cell carcinoma may reflect its indolent clinical prognosis...
  8. ncbi request reprint Topical suplatast tosilate (IPD) ameliorates Th2 cytokine-mediated dermatitis in caspase-1 transgenic mice by downregulating interleukin-4 and interleukin-5
    T Murakami
    Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie 514 8507, Japan
    Br J Dermatol 155:27-32. 2006
    ..AD is associated with Th2 cytokines including interleukin (IL)-4, IL-5, IL-13 and IL-10. Systemic administration of suplatast tosilate (IPD) is currently used to treat Th2 cytokine-mediated AD...
  9. ncbi request reprint Simultaneous development of two cases of eosinophilia-myalgia syndrome with the same lot of L-tryptophan in Japan
    T Mizutani
    Department of Dermatology, Mie University, School of Medicine, Japan
    J Am Acad Dermatol 25:512-7. 1991
    ..These findings implicate the existence of another factor in the development of eosinophilia-myalgia syndrome in addition to the suspect L-tryptophan...
  10. ncbi request reprint Keratinizing squamous epithelium associated with Syringocystadenoma papilliferum differentiates towards infrainfundibulum: case report with immunohistochemical study of cytokeratins
    I Kurokawa
    Department of Dermatology, Mie University Graduate School of Medicine, Edobashi, Tsu, Mie, Japan
    J Int Med Res 33:590-3. 2005
    ..Within the keratinizing squamous epithelium, CK1, 10, 14 and 17 were present, whereas the other CKs were absent. Based on CK expression, keratinizing squamous epithelium in SCAP seems to differentiate towards the infrainfundibulum...
  11. ncbi request reprint Trichoadenoma: cytokeratin expression suggesting differentiation towards the follicular infundibulum and follicular bulge regions
    I Kurokawa
    Br J Dermatol 153:1084-6. 2005