Akio Yamasaki

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. pmc Asymptomatic adenocarcinoma arising from a gastric duplication cyst: A case report
    Akio Yamasaki
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan Department of Surgery, Japanese Red Cross Fukuoka Hospital, Fukuoka 815 8555, Japan Electronic address
    Int J Surg Case Rep 25:16-20. 2016
  2. doi request reprint Nuclear factor kappaB-activated monocytes contribute to pancreatic cancer progression through the production of Shh
    Akio Yamasaki
    Department of Cancer Therapy and Research, Kyushu University, Maidashi, Higashi ku, Fukuoka, Japan
    Cancer Immunol Immunother 59:675-86. 2010
  3. ncbi request reprint Surface-bound TGF-beta1 on effusion-derived exosomes participates in maintenance of number and suppressive function of regulatory T-cells in malignant effusions
    Junji Wada
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Anticancer Res 30:3747-57. 2010
  4. ncbi request reprint The Hedgehog pathway is a possible therapeutic target for patients with estrogen receptor-negative breast cancer
    Chizu Kameda
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Anticancer Res 29:871-9. 2009
  5. ncbi request reprint The contribution of vascular endothelial growth factor to the induction of regulatory T-cells in malignant effusions
    Junji Wada
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Anticancer Res 29:881-8. 2009
  6. doi request reprint Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway
    Mio Ikebe
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Surg Oncol 100:725-31. 2009
  7. ncbi request reprint A protein-bound polysaccharide, PSK, enhances tumor suppression induced by docetaxel in a gastric cancer xenograft model
    Akio Yamasaki
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Anticancer Res 29:843-50. 2009
  8. doi request reprint VEGFR2 is selectively expressed by FOXP3high CD4+ Treg
    Hiroyuki Suzuki
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Eur J Immunol 40:197-203. 2010
  9. doi request reprint Dual blockade of phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways overcomes paclitaxel-resistance in colorectal cancer
    Rui Xu
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Japan
    Cancer Lett 306:151-60. 2011
  10. doi request reprint Intratumoral CD8(+) T/FOXP3 (+) cell ratio is a predictive marker for survival in patients with colorectal cancer
    Hiroyuki Suzuki
    Department of Cancer Therapy and Research, Kyushu University, Maidashi, Higashi ku, Fukuoka, Japan
    Cancer Immunol Immunother 59:653-61. 2010

Collaborators

Detail Information

Publications16

  1. pmc Asymptomatic adenocarcinoma arising from a gastric duplication cyst: A case report
    Akio Yamasaki
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan Department of Surgery, Japanese Red Cross Fukuoka Hospital, Fukuoka 815 8555, Japan Electronic address
    Int J Surg Case Rep 25:16-20. 2016
    ..Malignancy arising from a gastric duplication cyst is extremely rare. We herein report a very rare case of malignant transformation of a gastric duplication cyst...
  2. doi request reprint Nuclear factor kappaB-activated monocytes contribute to pancreatic cancer progression through the production of Shh
    Akio Yamasaki
    Department of Cancer Therapy and Research, Kyushu University, Maidashi, Higashi ku, Fukuoka, Japan
    Cancer Immunol Immunother 59:675-86. 2010
    ....
  3. ncbi request reprint Surface-bound TGF-beta1 on effusion-derived exosomes participates in maintenance of number and suppressive function of regulatory T-cells in malignant effusions
    Junji Wada
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Anticancer Res 30:3747-57. 2010
    ..This study analysed the contribution of malignant-effusion derived exosomes (Eff-Ex) to the number and function of regulatory T-cells (Treg) in malignant effusions...
  4. ncbi request reprint The Hedgehog pathway is a possible therapeutic target for patients with estrogen receptor-negative breast cancer
    Chizu Kameda
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Anticancer Res 29:871-9. 2009
    ....
  5. ncbi request reprint The contribution of vascular endothelial growth factor to the induction of regulatory T-cells in malignant effusions
    Junji Wada
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Anticancer Res 29:881-8. 2009
    ..Taken together, the data presented here indicate a contribution of VEGF to induction and/or maintenance of Tregs in patients with cancer...
  6. doi request reprint Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway
    Mio Ikebe
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Surg Oncol 100:725-31. 2009
    ..We have shown that lipopolysaccharide (LPS) promotes NF-kappaB activation in colon cancer cells and pancreatic cancer cells. However, it is unclear why inflammatory stimuli can induce NF-kappaB activation in cancer cells...
  7. ncbi request reprint A protein-bound polysaccharide, PSK, enhances tumor suppression induced by docetaxel in a gastric cancer xenograft model
    Akio Yamasaki
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Anticancer Res 29:843-50. 2009
    ..Based on these observations, in the present study the possibility that PSK could enhance TXT-mediated tumor suppression was examined in vivo and in vitro...
  8. doi request reprint VEGFR2 is selectively expressed by FOXP3high CD4+ Treg
    Hiroyuki Suzuki
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Eur J Immunol 40:197-203. 2010
    ..Such VEGFR2+ Treg exist in several tissues including PBMC and malignant effusion-derived lymphocytes. In conclusion, VEGFR2 may be a novel target for controlling Treg with highly suppressive function...
  9. doi request reprint Dual blockade of phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways overcomes paclitaxel-resistance in colorectal cancer
    Rui Xu
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Japan
    Cancer Lett 306:151-60. 2011
    ..In conclusion, PI3K is involved in low susceptibility of colorectal cancer to paclitaxel and dual PI3K/MAPK targeting agents may evolve a new paclitaxel-based chemotherapy for colorectal cancer...
  10. doi request reprint Intratumoral CD8(+) T/FOXP3 (+) cell ratio is a predictive marker for survival in patients with colorectal cancer
    Hiroyuki Suzuki
    Department of Cancer Therapy and Research, Kyushu University, Maidashi, Higashi ku, Fukuoka, Japan
    Cancer Immunol Immunother 59:653-61. 2010
    ..Importantly, itCD8(+) T/itFOXP3(+) cell ratio may be an independent prognostic factor. And, tumor-producing TGF-beta may contribute to the increased number of itFOXP3(+) cells...
  11. doi request reprint Hedgehog signaling regulates PDL-1 expression in cancer cells to induce anti-tumor activity by activated lymphocytes
    Hideya Onishi
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Electronic address
    Cell Immunol 310:199-204. 2016
    ..These results suggest that Hh signaling is one of regulatory pathways of PDL-1 expression under hypoxia and that inhibiting Hh signaling may induce lymphocyte anti-tumor activity...
  12. ncbi request reprint Induction of cytotoxic T lymphocytes by CEA peptide-pulsed γδ T-cells isolated from patients with advanced cancer
    Akio Yamasaki
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Anticancer Res 31:2419-24. 2011
    ..These results suggest that γδ T-cells from cancer patients may be ideal candidates for adoptive immunotherapy...
  13. ncbi request reprint Protein-bound Polysaccharide-K Inhibits Hedgehog Signaling Through Down-regulation of MAML3 and RBPJ Transcription Under Hypoxia, Suppressing the Malignant Phenotype in Pancreatic Cancer
    Akio Yamasaki
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Anticancer Res 36:3945-52. 2016
    ..Our results may lead to development of new treatments for refractory pancreatic cancer using PSK as a Hedgehog inhibitor. ..
  14. ncbi request reprint Sugar-carrying Polystyrenes Facilitate Harvesting of APCs from MLRs: Possible Application of Sugar-carrying Polystyrenes to Immunotherapy
    Akira Imaizumi
    Shukoukai Inc, Tokyo, Japan Department of Cancer Therapy and Research Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Anticancer Res 36:673-6. 2016
    ..The generated APCs also have a higher antigen-presenting ability compared to those generated in conventional flasks. Our results may contribute to the development of effective cancer immunotherapies. ..
  15. ncbi request reprint Regulatory T-cells are possible effect prediction markers of immunotherapy for cancer patients
    Junji Wada
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Anticancer Res 28:2401-8. 2008
    ..0034). These data suggest that the % Tregs among the PBMCs might be used as an effect prediction factor of immunotherapy for patients with advanced cancer...
  16. doi request reprint Hypoxia but not normoxia promotes Smoothened transcription through upregulation of RBPJ and Mastermind-like 3 in pancreatic cancer
    Hideya Onishi
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Electronic address
    Cancer Lett 371:143-50. 2016
    ..Our results suggest that hypoxia promotes SMO transcription through upregulation of MAML3 and RBPJ to induce proliferation, invasiveness and tumorigenesis in pancreatic cancer. ..