Kenzo Sonoda

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. ncbi request reprint Clinical significance of RCAS1 as a biomarker of uterine cancer
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Gynecol Oncol 103:924-31. 2006
  2. ncbi request reprint The clinical significance of tumor-associated antigen RCAS1 expression in the normal, hyperplastic, and malignant uterine endometrium
    K Sonoda
    Department of Obstetrics and Gynecology, Medical Institute of Bioregulation, Fukuoka, 812 8582, Japan
    Gynecol Oncol 79:424-9. 2000
  3. ncbi request reprint Association between RCAS1 expression and microenvironmental immune cell death in uterine cervical cancer
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Gynecol Oncol 97:772-9. 2005
  4. ncbi request reprint Invasive potency related to RCAS1 expression in uterine cervical cancer
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Gynecol Oncol 99:189-98. 2005
  5. ncbi request reprint Clinical significance of RCAS1 as a biomarker of ovarian cancer
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Oncol Rep 17:623-8. 2007
  6. ncbi request reprint Biologic significance of receptor-binding cancer antigen expressed on SiSo cells (RCAS1) as a pivotal regulator of tumor growth through angiogenesis in human uterine cancer
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Cancer 110:1979-90. 2007
  7. ncbi request reprint Clinical significance of heparin-binding epidermal growth factor-like growth factor and a disintegrin and metalloprotease 17 expression in human ovarian cancer
    Yoshihiro Tanaka
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Clin Cancer Res 11:4783-92. 2005
  8. doi request reprint The level of RCAS1 expression is inversely correlated with the number of vimentin-positive stromal cells in epithelial ovarian cancer
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Int J Gynecol Cancer 19:838-43. 2009
  9. ncbi request reprint Validation of HB-EGF and amphiregulin as targets for human cancer therapy
    Fusanori Yotsumoto
    Department of Obstetrics and Gynecology, School of Medicine, Fukuoka University, Fukuoka, Japan
    Biochem Biophys Res Commun 365:555-61. 2008
  10. doi request reprint Synergistic anti-tumor effect of paclitaxel with CRM197, an inhibitor of HB-EGF, in ovarian cancer
    Hiroshi Yagi
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Int J Cancer 124:1429-39. 2009

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Clinical significance of RCAS1 as a biomarker of uterine cancer
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Gynecol Oncol 103:924-31. 2006
    ..Although RCAS1 can induce apoptosis in normal peripheral lymphocytes, its biologic function in cancer patients is unclear. Here, we evaluated serum RCAS1 concentrations to clarify its biologic activity in uterine cancer...
  2. ncbi request reprint The clinical significance of tumor-associated antigen RCAS1 expression in the normal, hyperplastic, and malignant uterine endometrium
    K Sonoda
    Department of Obstetrics and Gynecology, Medical Institute of Bioregulation, Fukuoka, 812 8582, Japan
    Gynecol Oncol 79:424-9. 2000
    ..In this study, we examined whether the expression of RCAS1 is associated with the progression of the uterine endometrial neoplasms...
  3. ncbi request reprint Association between RCAS1 expression and microenvironmental immune cell death in uterine cervical cancer
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Gynecol Oncol 97:772-9. 2005
    ..Our aim was to evaluate the association between expression of these factors and microenvironmental lymphocyte apoptosis in this disease...
  4. ncbi request reprint Invasive potency related to RCAS1 expression in uterine cervical cancer
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Gynecol Oncol 99:189-98. 2005
    ..To investigate the relationship between RCAS1 and one such characteristic, tumor invasiveness, we examined RCAS1 expression in cervical neoplasms ranging from the precancerous state to invasive cancer...
  5. ncbi request reprint Clinical significance of RCAS1 as a biomarker of ovarian cancer
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Oncol Rep 17:623-8. 2007
    ..0074). RCAS1 may be a biomarker of ovarian cancer by virtue of its ability to predict results of treatment and inhibit immune cell growth...
  6. ncbi request reprint Biologic significance of receptor-binding cancer antigen expressed on SiSo cells (RCAS1) as a pivotal regulator of tumor growth through angiogenesis in human uterine cancer
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Cancer 110:1979-90. 2007
    ..To clarify whether RCAS1 exacerbates tumor progression, the authors investigated the association between RCAS1 expression and tumor growth potential...
  7. ncbi request reprint Clinical significance of heparin-binding epidermal growth factor-like growth factor and a disintegrin and metalloprotease 17 expression in human ovarian cancer
    Yoshihiro Tanaka
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Clin Cancer Res 11:4783-92. 2005
    ..We aimed to investigate the clinical significance of EGFR ligands and ADAM family in the lysophosphatidic acid-induced pathogenesis of ovarian cancer...
  8. doi request reprint The level of RCAS1 expression is inversely correlated with the number of vimentin-positive stromal cells in epithelial ovarian cancer
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Int J Gynecol Cancer 19:838-43. 2009
    ..RCAS1 may contribute to connective tissue remodeling by altering the number of vimentin-positive cells in epithelial ovarian cancer...
  9. ncbi request reprint Validation of HB-EGF and amphiregulin as targets for human cancer therapy
    Fusanori Yotsumoto
    Department of Obstetrics and Gynecology, School of Medicine, Fukuoka University, Fukuoka, Japan
    Biochem Biophys Res Commun 365:555-61. 2008
    ..In lung cancer cells, any EGFR ligand was not recognized as a validated target for cancer therapy. These results suggest that HB-EGF and amphiregulin are promising targets for cancer therapy...
  10. doi request reprint Synergistic anti-tumor effect of paclitaxel with CRM197, an inhibitor of HB-EGF, in ovarian cancer
    Hiroshi Yagi
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Int J Cancer 124:1429-39. 2009
    ..Accordingly, inhibitory agents against HB-EGF, such as CRM197, represent possible chemotherapeutic and chemosensitizing agents for ovarian cancer...
  11. doi request reprint Receptor-binding cancer antigen expressed on SiSo cells induces apoptosis via ectodomain shedding
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Exp Cell Res 316:1795-803. 2010
    ..K562 apoptosis could be induced only by co-culturing with SiSo or soluble RCAS1. RCAS1 is thus secreted by ectodomain shedding, which may represent a pivotal step in RCAS1-induced apoptosis initiation...
  12. ncbi request reprint The biological role of the unique molecule RCAS1: a bioactive marker that induces connective tissue remodeling and lymphocyte apoptosis
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Front Biosci 13:1106-16. 2008
    ..Further exploration of the biological function of RCAS1 should help in the development of new therapeutic strategies against human malignancies...
  13. doi request reprint Sentinel node detection with (99m)Tc phytate alone is satisfactory for cervical cancer patients undergoing radical hysterectomy and pelvic lymphadenectomy
    Shinji Ogawa
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Int J Clin Oncol 15:52-8. 2010
    ..We assessed feasibility and accuracy of SLN detection using (99m)Tc phytate in patients with cervical cancer...
  14. doi request reprint Efficacy of aprepitant for the prevention of chemotherapy-induced nausea and vomiting with a moderately emetogenic chemotherapy regimen: a multicenter, placebo-controlled, double-blind, randomized study in patients with gynecologic cancer receiving paclit
    Hideaki Yahata
    Department of Obstetrics and Gynecology, Kyushu University Hospital, Fukuoka, Japan
    Int J Clin Oncol 21:491-7. 2016
    ..While aprepitant has a prophylactic effect against vomiting caused by high-dose cisplatin, the benefits of aprepitant have not been clearly demonstrated in patients receiving paclitaxel and carboplatin (TC) combination chemotherapy...
  15. pmc Regulation of the Mechanism of TWIST1 Transcription by BHLHE40 and BHLHE41 in Cancer Cells
    Kazuo Asanoma
    Department of Obstetrics and Gynecology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
    Mol Cell Biol 35:4096-109. 2015
    ..We propose that BHLHE40/41 are promising markers to predict the aggressiveness of each HEC case and that molecular targeting strategies involving BHLHE40/41 and SP1 may effectively regulate HEC progression. ..
  16. ncbi request reprint Identification of the Critical Site of Calponin 1 for Suppression of Ovarian Cancer Properties
    Takako Yamane
    Department of Obstetrics and Gynecology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
    Anticancer Res 35:5993-9. 2015
    ..Although several studies have demonstrated the tumor suppressive function of CNN1 (calponin 1), no studies have performed a site-specific analysis of CNN1 on tumor cell activities...
  17. ncbi request reprint Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy
    Shingo Miyamoto
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Cancer Res 64:5720-7. 2004
    ....
  18. ncbi request reprint Expression of RCAS1 in female genital organs
    Yoshiaki Kawano
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Maidashi, Fukuoka, Japan
    Int J Gynecol Pathol 24:330-4. 2005
    ..No significant correlation was found between RCAS1 expression and MIB-1 index/apoptotic index. RCAS1 may affect these metaplastic processes and tumor progression...
  19. doi request reprint Diagnostic value of squamous cell change associated with endometrial carcinoma: A cytopathologic approach
    Yukie Toomine
    Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Diagn Cytopathol 44:187-94. 2016
    ....
  20. pmc FBXW7 is involved in the acquisition of the malignant phenotype in epithelial ovarian tumors
    Shoko Kitade
    Department of Obstetrics and Gynecology, School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Cancer Sci 107:1399-1405. 2016
    ..Thus, FBXW7 expression was downregulated in ovarian cancers, and was associated with p53 mutations and the DNA methylation status of the 5'-upstream regions of FBXW7...
  21. ncbi request reprint Oncologic and obstetric outcomes and complications during pregnancy after fertility-sparing abdominal trachelectomy for cervical cancer: a retrospective review
    Kaoru Okugawa
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Int J Clin Oncol . 2016
    ..The purpose of this study is to evaluate oncologic and obstetric outcomes and complications after abdominal trachelectomy...
  22. ncbi request reprint Postoperative adjuvant chemotherapy with cisplatin, cyclophosphamide, and anthracycline (doxorubicin, epirubicin, pirarubicin) for endometrial cancer
    Hideaki Yahata
    Department of Obstetrics and Gynecology, Kyushu University Hospital, 3 1 1 Maidashi, Higashi ku, 812 8582, Fukuoka, Japan
    Int J Clin Oncol 9:317-21. 2004
    ..The aim of this study was to retrospectively assess the efficacy and toxicity of combination chemotherapy using cisplatin, cyclophosphamide, and anthracy-clines in patients with stage III/IV adenocarcinoma of the endometrium...
  23. ncbi request reprint Retrospective Analysis of Concurrent Chemoradiation with Triweekly Cisplatin plus 5-Fluorouracil Versus Weekly Cisplatin in Cervical Cancer
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Anticancer Res 35:3447-54. 2015
    ..Concurrent chemoradiation (CCRT) is the standard treatment for locally advanced cervical cancer. The purpose of the study was to compare the outcomes of triweekly cisplatin plus 5-fluorouracil and weekly cisplatin regimens...
  24. doi request reprint Low-dose mithramycin exerts its anticancer effect via the p53 signaling pathway and synergizes with nutlin-3 in gynecologic cancers
    Tatsuhiro Ohgami
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Cancer Sci 101:1387-95. 2010
    ..These observations provide a better understanding of the mechanisms of mithramycin activity, and suggest a potential role for combining mithramycin and nutlin-3 as a chemotherapeutic treatment for gynecologic cancers...
  25. pmc SNP55, a new functional polymorphism of MDM2-P2 promoter, contributes to allele-specific expression of MDM2 in endometrial cancers
    Kanako Okamoto
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    BMC Med Genet 16:67. 2015
    ..Although many studies have been performed to demonstrate the mechanism of allele-specific expression (ASE) on SNP309, they have only utilized in vitro techniques. It is unknown whether ASE of MDM2 is ascribed solely to SNP309, in vivo...
  26. ncbi request reprint HOP/NECC1, a novel regulator of mouse trophoblast differentiation
    Kazuo Asanoma
    Division of Molecular and Cell Therapeutics, Kyushu University, Japan
    J Biol Chem 282:24065-74. 2007
    ....
  27. ncbi request reprint Expression of lysophosphatidic acid receptors and vascular endothelial growth factor mediating lysophosphatidic acid in the development of human ovarian cancer
    Takuji Fujita
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Maidashi, Higashi ku, 812 8582, Fukuoka, Japan
    Cancer Lett 192:161-9. 2003
    ..617, P<0.0001; gamma=0.431, P<0.001) in patients with cancer. These results suggested that LPA(2) and LPA(3) may be involved in VEGF expression mediated by LPA signals in human ovarian oncogenesis...
  28. doi request reprint Ovarian high-grade serous carcinoma with a noninvasive growth pattern simulating a serous borderline tumor
    Hiroko Imamura
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hum Pathol 46:1455-63. 2015
    ..In conclusion, our results showed that a cytologically HG-noninv growth pattern simulating an SBT is a morphological spectrum of HGSC, but not a true SBT. ..
  29. pmc A disintegrin and metalloproteinase 9 is involved in ectodomain shedding of receptor-binding cancer antigen expressed on SiSo cells
    Kenzo Sonoda
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Biomed Res Int 2014:482396. 2014
    ....
  30. pmc Apoptotic function of tumor-associated antigen RCAS1 in oral squamous cell carcinoma
    Hideaki Tanaka
    Division of Maxillofacial Diagnostic and Surgical Sciences, Section of Oral and Maxillofacial Oncology, Faculty of Dental Science, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    J Transl Med 12:112. 2014
    ..The aim of this study was to investigate expression patterns of RCAS1 and the effect on apoptosis in oral squamous cell carcinoma (OSCC) cell lines...