Hidemasa Furue

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. pmc Actions of brain-derived neurotrophic factor on spinal nociceptive transmission during inflammation in the rat
    Satoru Matayoshi
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
    J Physiol 569:685-95. 2005
  2. pmc Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons
    Stefan K Georgiev
    Division of Anaesthesiology, Niigata University Graduate School of Medical and Dental Sciences, 1 757 Asahimachi, Chuo Ku, Niigata 951 8510, Japan
    Mol Pain 6:25. 2010
  3. ncbi request reprint Sensory processing and functional reorganization of sensory transmission under pathological conditions in the spinal dorsal horn
    Hidemasa Furue
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Neurosci Res 48:361-8. 2004
  4. doi request reprint Actions of propofol on substantia gelatinosa neurones in rat spinal cord revealed by in vitro and in vivo patch-clamp recordings
    Tomonori Takazawa
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Eur J Neurosci 29:518-28. 2009
  5. pmc Cell-type-specific excitatory and inhibitory circuits involving primary afferents in the substantia gelatinosa of the rat spinal dorsal horn in vitro
    Toshiharu Yasaka
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Physiol 581:603-18. 2007
  6. pmc TRPA1-expressing primary afferents synapse with a morphologically identified subclass of substantia gelatinosa neurons in the adult rat spinal cord
    Daisuke Uta
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Eur J Neurosci 31:1960-73. 2010
  7. pmc Direct excitation of deep dorsal horn neurones in the rat spinal cord by the activation of postsynaptic P2X receptors
    Hiroaki Shiokawa
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Japan
    J Physiol 573:753-63. 2006
  8. ncbi request reprint Reduced pain behaviors and extracellular signal-related protein kinase activation in primary sensory neurons by peripheral tissue injury in mice lacking platelet-activating factor receptor
    Makoto Tsuda
    Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Maidashi, Higashi ku, Fukuoka, Japan
    J Neurochem 102:1658-68. 2007
  9. ncbi request reprint Tonic inhibitory role of alpha4beta2 subtype of nicotinic acetylcholine receptors on nociceptive transmission in the spinal cord in mice
    Md Harunor Rashid
    Department of Integrative Physiology, Kyushu University Graduate School of Medical Sciences, Fukuoka 812 8582, Japan
    Pain 125:125-35. 2006
  10. ncbi request reprint Slow oscillation of membrane currents mediated by glutamatergic inputs of rat somatosensory cortical neurons: in vivo patch-clamp analysis
    Atsushi Doi
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Eur J Neurosci 26:2565-75. 2007

Collaborators

Detail Information

Publications38

  1. pmc Actions of brain-derived neurotrophic factor on spinal nociceptive transmission during inflammation in the rat
    Satoru Matayoshi
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
    J Physiol 569:685-95. 2005
    ..BDNF may thereafter induce monosynaptic Abeta afferents to the SG, thereby developing hyperalgesia and/or allodynia during inflammation...
  2. pmc Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons
    Stefan K Georgiev
    Division of Anaesthesiology, Niigata University Graduate School of Medical and Dental Sciences, 1 757 Asahimachi, Chuo Ku, Niigata 951 8510, Japan
    Mol Pain 6:25. 2010
    ..We further evaluated the effects of xenon on innocuous and noxious stimuli using in vivo patch-clamp method...
  3. ncbi request reprint Sensory processing and functional reorganization of sensory transmission under pathological conditions in the spinal dorsal horn
    Hidemasa Furue
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Neurosci Res 48:361-8. 2004
    ..We review here recent results demonstrating plastic changes in SG under pathological conditions...
  4. doi request reprint Actions of propofol on substantia gelatinosa neurones in rat spinal cord revealed by in vitro and in vivo patch-clamp recordings
    Tomonori Takazawa
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Eur J Neurosci 29:518-28. 2009
    ..We conclude that systemic bolus injection of propofol reversibly depressed nociceptive transmission, at least in part, by enhancing postsynaptic GABA(A) receptor-mediated responses in the SG...
  5. pmc Cell-type-specific excitatory and inhibitory circuits involving primary afferents in the substantia gelatinosa of the rat spinal dorsal horn in vitro
    Toshiharu Yasaka
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Physiol 581:603-18. 2007
    ..These results make it possible to identify primary afferent circuits associated with particular types of SG neurone...
  6. pmc TRPA1-expressing primary afferents synapse with a morphologically identified subclass of substantia gelatinosa neurons in the adult rat spinal cord
    Daisuke Uta
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Eur J Neurosci 31:1960-73. 2010
    ..The presence of TRPA1 channels on the central terminals raises the possibility of bidirectional modulatory action in morphologically identified subclasses of SG neurons...
  7. pmc Direct excitation of deep dorsal horn neurones in the rat spinal cord by the activation of postsynaptic P2X receptors
    Hiroaki Shiokawa
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Japan
    J Physiol 573:753-63. 2006
    ..In addition, the data relating to the developmental increase in the functional P2X receptors suggest that purinergic signalling may thus be more common in somatosensory transmission with maturation...
  8. ncbi request reprint Reduced pain behaviors and extracellular signal-related protein kinase activation in primary sensory neurons by peripheral tissue injury in mice lacking platelet-activating factor receptor
    Makoto Tsuda
    Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Maidashi, Higashi ku, Fukuoka, Japan
    J Neurochem 102:1658-68. 2007
    ..Furthermore, U0126, a specific inhibitor of the ERK pathway suppressed the persistent pain by formalin. Thus, PAFR may play an important role in both persistent pain and the sensitization of primary sensory neurons after tissue injury...
  9. ncbi request reprint Tonic inhibitory role of alpha4beta2 subtype of nicotinic acetylcholine receptors on nociceptive transmission in the spinal cord in mice
    Md Harunor Rashid
    Department of Integrative Physiology, Kyushu University Graduate School of Medical Sciences, Fukuoka 812 8582, Japan
    Pain 125:125-35. 2006
    ....
  10. ncbi request reprint Slow oscillation of membrane currents mediated by glutamatergic inputs of rat somatosensory cortical neurons: in vivo patch-clamp analysis
    Atsushi Doi
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Eur J Neurosci 26:2565-75. 2007
    ..In addition, GABAergic system in the thalamus can affect the frequency, but is not essentially implicated in the genesis of the slow oscillation...
  11. ncbi request reprint Direct GABAergic and glycinergic inhibition of the substantia gelatinosa from the rostral ventromedial medulla revealed by in vivo patch-clamp analysis in rats
    Go Kato
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Neurosci 26:1787-94. 2006
    ..These findings suggest that the RVM-mediated antinociceptive effects on noxious inputs to the SG may be exerted preferentially by the direct GABAergic and glycinergic pathways to the SG...
  12. pmc Electrophysiological mapping of the nociceptive inputs to the substantia gelatinosa in rat horizontal spinal cord slices
    Go Kato
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Physiol 560:303-15. 2004
    ..In addition, the widespread distribution of the inhibitory inputs may thus play a role as a lateral inhibitory network and thereby prevent the expansion of the excitatory inputs of noxious stimuli...
  13. ncbi request reprint In vivo and in vitro patch-clamp recording analysis of the process of sensory transmission in the spinal cord and sensory cortex
    Megumu Yoshimura
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Physiol Anthropol Appl Human Sci 24:93-7. 2005
    ..These observations suggest that the synaptic responses in cortical neurons are processed in a more complex manner; and this may be due to the reciprocal synaptic connection between thalamus and cortex...
  14. pmc Bone cancer induces a unique central sensitization through synaptic changes in a wide area of the spinal cord
    Yoshikazu Yanagisawa
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Mol Pain 6:38. 2010
    ..In this study, we examined excitatory synaptic responses evoked in substantia gelatinosa (SG, lamina II) neurons in spinal cord slices of adult mice bearing bone cancer, using whole-cell voltage-clamp recording techniques...
  15. ncbi request reprint [Mechanism of antinociceptive action of calcitonin--involvement of descending serotonergic system]
    Megumu Yoshimura
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University
    Nihon Rinsho 63:211-3. 2005
  16. ncbi request reprint Mechanisms for the anti-nociceptive actions of the descending noradrenergic and serotonergic systems in the spinal cord
    Megumu Yoshimura
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Pharmacol Sci 101:107-17. 2006
    ....
  17. pmc Actions of noradrenaline on substantia gelatinosa neurones in the rat spinal cord revealed by in vivo patch recording
    Motoki Sonohata
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Physiol 555:515-26. 2004
    ....
  18. pmc Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo
    Junichi Hachisuka
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    J Neurophysiol 104:271-9. 2010
    ..These observations suggest that the long-lasting-firing C neurons in rat DRG sensitive to 5-HT are responsible for conveying pruritic information to the spinal cord...
  19. ncbi request reprint Application of in vivo patch-clamp technique to pharmacological analysis of synaptic transmission in the CNS
    Megumu Yoshimura
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Nihon Yakurigaku Zasshi 124:111-8. 2004
    ..Thus, combinatorial studies with dissociated or cultured neurons or with slice preparations are clearly required for further understanding of pharmacological properties of neurons in the CNS...
  20. pmc Selective activation of primary afferent fibers evaluated by sine-wave electrical stimulation
    Kohei Koga
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Mol Pain 1:13. 2005
    ..Thus, the transcutaneous sine-wave stimulation can be applied to evaluate functional changes of sensory transmission by comparing thresholds with the three stimulus frequencies...
  21. pmc Presynaptic modulation by neuromedin U of sensory synaptic transmission in rat spinal dorsal horn neurones
    Maiko Moriyama
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashiku, Fukuoka 812 8582, Japan
    J Physiol 559:707-13. 2004
    ..This may account for the spinal mechanisms of the NMU-induced hyperalgesia reported previously...
  22. ncbi request reprint [Spinal anti-nociceptive effect of calcitonin in an osteoporotic model rat--functional recovery of descending serotonergic inhibition]
    Hidemasa Furue
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University
    Clin Calcium 15:163-7. 2005
    ..Inhibitory effect of serotonin on mechanical noxious inputs to dorsal horn neurons was reduced in OVX rats. This mechanical hyperalgesia observation in OVX rats was attenuated by calcitonin treatment...
  23. ncbi request reprint [Methods for in vivo patch-clamp recordings and their applications: synaptic responses in somatosensory cortex]
    Megumu Yoshimura
    Nihon Yakurigaku Zasshi 128:381-7. 2006
  24. ncbi request reprint Alterations in primary afferent input to substantia gelatinosa of adult rat spinal cord after neonatal capsaicin treatment
    Kun Yang
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Neurosci Res 74:928-33. 2003
    ..Our electrophysiological data suggest that NCT diminishes primary afferent C-fiber inputs while enhancing Abeta-fiber direct innervation in the SG in adulthood...
  25. ncbi request reprint Somatostatin directly inhibits substantia gelatinosa neurons in adult rat spinal dorsal horn in vitro
    Nan Jiang
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Neurosci Res 47:97-107. 2003
    ....
  26. ncbi request reprint Pre- and postsynaptic inhibition mediated by GABA(B) receptors in rat ventrolateral periaqueductal gray neurons
    Kun Yang
    Department of Integrative Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Biochem Biophys Res Commun 302:233-7. 2003
    ..The overall effects might influence an output of ventrolateral PAG neurons that build up the descending pain control system to the spinal dorsal horn...
  27. ncbi request reprint Anandamide inhibits excitatory transmission to rat substantia gelatinosa neurones in a manner different from that of capsaicin
    Ceng Luo
    Department of Physiology, Saga Medical School, 5 1 1 Nabeshima, Saga 849 8501, Japan
    Neurosci Lett 321:17-20. 2002
    ..It is concluded that unlike capsaicin, anandamide inhibits more effectively Adelta-fibre than C-fibre-mediated excitatory transmission in the SG, possibly through the activation of the cannabinoid receptor...
  28. ncbi request reprint GABA-mediated inhibition of glutamate release during ischemia in substantia gelatinosa of the adult rat
    Noriaki Matsumoto
    Department of Physiology, Saga Medical School, Japan
    J Neurophysiol 89:257-64. 2003
    ..This action might protect SG neurons from an excessive excitation mediated by L-glutamate during ischemia...
  29. doi request reprint N-ethylmaleimide-sensitive fusion protein (NSF) is involved in central sensitization in the spinal cord through GluR2 subunit composition switch after inflammation
    Tayo Katano
    Department of Medical Chemistry, Kansai Medical University, Moriguchi 570 8506, Japan
    Eur J Neurosci 27:3161-70. 2008
    ..These results suggest that peripheral inflammation gives rise to central sensitization in the spinal cord through subunit composition switch of AMPA receptors in the late phase...
  30. ncbi request reprint [Function of spinal GABA receptor and its modulation]
    Megumu Yoshimura
    Columbia University, USA
    Masui 56:S141-51. 2007
  31. ncbi request reprint Alpha 2 adrenoceptor-mediated presynaptic inhibition of primary afferent glutamatergic transmission in rat substantia gelatinosa neurons
    Yasuhiko Kawasaki
    Department of Physiology, Saga Medical School, Japan
    Anesthesiology 98:682-9. 2003
    ..Although intrathecal administration of norepinephrine is known to produce analgesia, cellular mechanisms for this action have not yet been fully understood...
  32. ncbi request reprint [Functional analysis of pain pathway in posterior horn cells using spinal cord slice and in-vivo patch clamp method]
    Megumu Yoshimura
    Masui 51:S79-88. 2002
  33. ncbi request reprint Cadherin-8 is required for the first relay synapses to receive functional inputs from primary sensory afferents for cold sensation
    Sachihiro C Suzuki
    RIKEN Center for Developmental Biology, Chuo Ku, Kobe 650 0047, Japan
    J Neurosci 27:3466-76. 2007
    ..The cad8-/- mice also showed a reduced sensitivity to cold temperature. These results demonstrate that cad8 is essential for establishing the physiological coupling between cold-sensitive sensory neurons and their target DH neurons...
  34. ncbi request reprint Changes in properties of substantia gelatinosa neurons after surgical incision in the rat: in vivo patch-clamp analysis
    Mikito Kawamata
    Department of Anesthesiology, Sapporo Medical University School of Medicine, Sapporo, Japan
    Anesthesiology 104:432-40. 2006
    ..In this study, changes in properties of substantia gelatinosa neurons and their sensitivity to systemic administration of lidocaine after surgical incision were investigated using the in vivo patch-clamp technique...
  35. pmc Direct inhibition of substantia gelatinosa neurones in the rat spinal cord by activation of dopamine D2-like receptors
    Akihiro Tamae
    Department of Physiology, Faculty of Medicine, Saga University, Saga 849 8501, Japan
    J Physiol 568:243-53. 2005
    ..This may be a possible mechanism for antinociception by the descending dopaminergic pathway...
  36. ncbi request reprint Activation of central terminal vanilloid receptor-1 receptors and alpha beta-methylene-ATP-sensitive P2X receptors reveals a converged synaptic activity onto the deep dorsal horn neurons of the spinal cord
    Terumasa Nakatsuka
    McKnight Brain Institute of the University of Florida and Division of Neuroscience, Department of Oral Surgery, College of Dentistry, University of Florida, Gainesville, Florida 32610, USA
    J Neurosci 22:1228-37. 2002
    ..These convergent pathways may provide a mechanism of sensory integration for two chemically defined sensory inputs and may have implications in different sensory states...
  37. ncbi request reprint [Recent insights into mechanisms for analgesic effect by calcitonin]
    Akitoshi Ito
    Research Center, Asahi Kasei Pharma Co Ltd
    Nihon Rinsho 65:386-90. 2007
  38. ncbi request reprint [Method of in-vivo patch clamp recording from anterior horn neurons in rats and mice]
    Hidemasa Furue
    Nihon Seirigaku Zasshi 65:315-21. 2003