Toshihiro Nakashima

Summary

Affiliation: Kyoto Institute of Technology
Country: Japan

Publications

  1. ncbi request reprint Hypothalamic 11,12-epoxyeicosatrienoic acid attenuates fever induced by central interleukin-1beta in the rat
    T Nakashima
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Neurosci Lett 310:141-4. 2001
  2. ncbi request reprint Brain oxytocin augments stress-induced long-lasting plasma adrenocorticotropic hormone elevation in rats
    Toshihiro Nakashima
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto, Japan
    Neurosci Lett 321:161-4. 2002
  3. ncbi request reprint Attenuation of stress-induced elevations in plasma ACTH level and body temperature in rats by green odor
    Toshihiro Nakashima
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Physiol Behav 80:481-8. 2004
  4. doi request reprint IgLON cell adhesion molecule Kilon is a crucial modulator for synapse number in hippocampal neurons
    Takashi Hashimoto
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Brain Res 1224:1-11. 2008
  5. ncbi request reprint Matrix-degrading enzymes tissue plasminogen activator and matrix metalloprotease-3 in the hypothalamo-neurohypophysial system
    Seiji Miyata
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Kyoto, Japan
    Brain Res 1058:1-9. 2005
  6. doi request reprint Localization of plasminogen in mouse hippocampus, cerebral cortex, and hypothalamus
    Yuki Taniguchi
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto, 606 8585, Japan
    Cell Tissue Res 343:303-17. 2011
  7. doi request reprint Order of exposure to pleasant and unpleasant odors affects autonomic nervous system response
    Yuko Horii
    Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Behav Brain Res 243:109-17. 2013
  8. doi request reprint Expression of chondroitin sulfate proteoglycans in barrel field of mouse and rat somatosensory cortex
    Michiru Nakamura
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Brain Res 1252:117-29. 2009
  9. ncbi request reprint Synaptic adhesion molecule OBCAM; synaptogenesis and dynamic internalization
    Mayumi Yamada
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Brain Res 1165:5-14. 2007
  10. ncbi request reprint Perineuronal nets protect against amyloid beta-protein neurotoxicity in cultured cortical neurons
    Seiji Miyata
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Brain Res 1150:200-6. 2007

Collaborators

  • Seiji Miyata
  • Yuko Horii
  • Katsuya Nagai
  • Shohei Maekawa
  • Takashi Hashimoto
  • Atsuhiko Oohira
  • Akira Murakami
  • Naoko Inoue
  • Nobuo Nagai
  • Shoko Morita
  • Shohei Fukushima
  • Yousuke Nakano
  • Eriko Furube
  • Yuki Taniguchi
  • Michiru Nakamura
  • Tomoki Yoshihara
  • Mayumi Yamada
  • Yasuyuki Eda
  • Akio Wanaka
  • Masanobu Itoh
  • Osamu Matsuo
  • Kiyotaka Okada
  • Yoshikazu Nikaido
  • Keiko Nakano
  • Shinichiro Tsuyama
  • Shuhei Hashiguchi
  • Yuji Ito
  • Sayaka Kuba
  • Akifumi Kyuno
  • Kazuhisa Sugimura
  • Sho Takiguchi
  • Takeshi Iwatsubo
  • Koichi Tanaka
  • Maiko Higuchi
  • Noriko Hayashi
  • Toshio Murakami
  • Kouichi Shiosaki
  • Hiroshi Yonemura
  • Mitsuo Honda
  • Kazuhiko Kimachi
  • Sachio Tokiyoshi
  • Naoki Yamamoto
  • Hirofumi Higuchi
  • Mari Takizawa
  • Satoshi Koyanagi
  • Kiyoshi Osatomi
  • Keiichi Makizumi
  • Hiroaki Maeda
  • Shuzo Matsushita

Detail Information

Publications16

  1. ncbi request reprint Hypothalamic 11,12-epoxyeicosatrienoic acid attenuates fever induced by central interleukin-1beta in the rat
    T Nakashima
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Neurosci Lett 310:141-4. 2001
    ..Intra-PO/AH injection of 11,12-EET did not alter normal body temperature. The results suggest that 11,12-EET acts in the hypothalamus as an endogenous antipyretic...
  2. ncbi request reprint Brain oxytocin augments stress-induced long-lasting plasma adrenocorticotropic hormone elevation in rats
    Toshihiro Nakashima
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto, Japan
    Neurosci Lett 321:161-4. 2002
    ..05) compared with controls. The results suggest that endogenous brain OXT enhances the long-lasting but not immediate HPA axis response to stress...
  3. ncbi request reprint Attenuation of stress-induced elevations in plasma ACTH level and body temperature in rats by green odor
    Toshihiro Nakashima
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Physiol Behav 80:481-8. 2004
    ..These data suggest that green odor extracted from green leaves has a relieving effect on plasma ACTH and T(b) levels induced by an immobilization stress for not only immediate but also long-lasting periods...
  4. doi request reprint IgLON cell adhesion molecule Kilon is a crucial modulator for synapse number in hippocampal neurons
    Takashi Hashimoto
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Brain Res 1224:1-11. 2008
    ..These results demonstrate the alteration of modulatory function of Kilon for the number of dendritic synapses concomitant with changes in its localization and detergent solubility during neuronal culture development...
  5. ncbi request reprint Matrix-degrading enzymes tissue plasminogen activator and matrix metalloprotease-3 in the hypothalamo-neurohypophysial system
    Seiji Miyata
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Kyoto, Japan
    Brain Res 1058:1-9. 2005
    ....
  6. doi request reprint Localization of plasminogen in mouse hippocampus, cerebral cortex, and hypothalamus
    Yuki Taniguchi
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto, 606 8585, Japan
    Cell Tissue Res 343:303-17. 2011
    ..Thus, plasminogen is highly expressed in specific populations of hippocampal, cortical, and hypothalamic neurons, and plasminogen-containing vesicles are mainly observed at neuronal somata...
  7. doi request reprint Order of exposure to pleasant and unpleasant odors affects autonomic nervous system response
    Yuko Horii
    Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Behav Brain Res 243:109-17. 2013
    ..Our study should provide new insights into our understanding of the physiological response in the autonomic nervous system related to odor memory and discrimination and point to areas that require further research...
  8. doi request reprint Expression of chondroitin sulfate proteoglycans in barrel field of mouse and rat somatosensory cortex
    Michiru Nakamura
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Brain Res 1252:117-29. 2009
    ..These data indicate species-dependent heterogeneity of CSPG expression and activity-dependent formation of PNNs in the PMBSF, but CS GAGs have no crucial function in constructing the barrel structures during early postnatal development...
  9. ncbi request reprint Synaptic adhesion molecule OBCAM; synaptogenesis and dynamic internalization
    Mayumi Yamada
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Brain Res 1165:5-14. 2007
    ..These results indicate that OBCAM is a synaptic cell adhesion molecule concerning synaptogenesis and its surface localization is dynamically regulated in response to neuronal activity...
  10. ncbi request reprint Perineuronal nets protect against amyloid beta-protein neurotoxicity in cultured cortical neurons
    Seiji Miyata
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Brain Res 1150:200-6. 2007
    ..The treatment of glutamate killed not only PNs-free cortical neurons but also PNs-associated neurons. These results suggest that CS glycosaminoglycans on PNs are responsible for protecting neurons from Abeta1-42 neurotoxicity...
  11. doi request reprint Astrocytic TLR4 expression and LPS-induced nuclear translocation of STAT3 in the sensory circumventricular organs of adult mouse brain
    Yousuke Nakano
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    J Neuroimmunol 278:144-58. 2015
    ..A microglia inhibitor minocycline largely suppressed lipopolysaccharide-induced astrocytic nuclear translocation of STAT3 in the OVLT and AP, but its effect was less in the SFO. ..
  12. doi request reprint Robust increase of microglia proliferation in the fornix of hippocampal axonal pathway after a single LPS stimulation
    Shohei Fukushima
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    J Neuroimmunol 285:31-40. 2015
    ..In conclusion, the present study indicates that the hippocampal neuronal system has a higher proliferative microglial capability against LPS-induced inflammatory administration compared with other brain regions. ..
  13. doi request reprint Exposure to TMT odor affects adrenal sympathetic nerve activity and behavioral consequences in rats
    Yuko Horii
    Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Behav Brain Res 214:317-22. 2010
    ..Exposure to TMT odor likely regulates the controlling autonomic function and output to a motor system simultaneously, evoking behavioral stress responses...
  14. ncbi request reprint Chondroitin sulfate proteoglycan phosphacan/RPTPbeta in the hypothalamic magnocellular nuclei
    Seiji Miyata
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Brain Res 949:112-21. 2002
    ..The present results indicate the high expression of the CSPG, phosphacan/RPTPbeta at the extracellular space in the hypothalamic AVP- and OXT-secreting magnocellular neurons...
  15. pmc Sequential immunization with V3 peptides from primary human immunodeficiency virus type 1 produces cross-neutralizing antibodies against primary isolates with a matching narrow-neutralization sequence motif
    Yasuyuki Eda
    AIDS Research Center, National Institute of Infectious Diseases, Shinjuku ku, Tokyo 162 8640, Japan
    J Virol 80:5552-62. 2006
    ..Indeed, they help lay the groundwork for the development of HIV-1 vaccine strategies that use sequential immunization with biologically relevant peptides to overcome difficulties associated with otherwise poorly immunogenic epitopes...
  16. doi request reprint Immunoreactivity of phage library-derived human single-chain antibodies to amyloid beta conformers in vitro
    Tomoki Yoshihara
    Department of Bioengineering, Faculty of Engineering, Kagoshima University, Korimoto 1 21 40, Kagoshima, Kagoshima, Japan
    J Biochem 143:475-86. 2008
    ..Although it is believed that N-terminus-recognizing antibodies tend to show the capability to inhibit A beta 1-42 fibrillation, B6 is the first human inhibitory antibody recognizing the C-terminus of A beta 1-42...