Kazuhisa Bessho

Summary

Affiliation: Kyoto University
Country: Japan

Publications

  1. ncbi request reprint Bone induction by Escherichia coli -derived recombinant human bone morphogenetic protein-2 compared with Chinese hamster ovary cell-derived recombinant human bone morphogenetic protein-2
    K Bessho
    Assistant Professor, Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Br J Oral Maxillofac Surg 38:645-649. 2000
  2. ncbi request reprint Osteoinduction by recombinant human bone morphogenetic protein-2 at intramuscular, intermuscular, subcutaneous and intrafatty sites
    Y Okubo
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Japan
    Int J Oral Maxillofac Surg 29:62-6. 2000
  3. pmc Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations
    Honoka Kiso
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Shogoin Kawahara cho, Sakyo ku, Kyoto, Japan
    PLoS ONE 9:e96938. 2014
  4. doi request reprint Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse
    Akiko Murashima-Suginami
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Shogoin Kawahara cho, Sakyo ku, Kyoto 606 8507, Japan
    Biochem Biophys Res Commun 369:1012-6. 2008
  5. ncbi request reprint Osteoinduction by bone morphogenetic protein-2 via adenoviral vector under transient immunosuppression
    Y Okubo
    Graduate School of Medicine, Kyoto University, 54 Kawahara cho, Shogoin, Sakyo ku, Kyoto, 606 8507, Japan
    Biochem Biophys Res Commun 267:382-7. 2000
  6. ncbi request reprint Effect of FK506 on osteoinduction by recombinant human bone morphogenetic protein-2
    Shinji Kaihara
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, 54 Kawahara cho, Shogoin, Sakyo ku, Japan
    Life Sci 72:247-56. 2002
  7. pmc Simultaneous gene transfer of bone morphogenetic protein (BMP) -2 and BMP-7 by in vivo electroporation induces rapid bone formation and BMP-4 expression
    Mariko Kawai
    Department of Oral Morphology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700 8525, Japan
    BMC Musculoskelet Disord 7:62. 2006
  8. ncbi request reprint Osteoinduction by bone morphogenetic protein 2-expressing adenoviral vector: application of biomaterial to mask the host immune response
    Junya Sonobe
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606 8507, Japan
    Hum Gene Ther 15:659-68. 2004
  9. ncbi request reprint The time course study of osteoinduction by bone morphogenetic protein-2 via adenoviral vector
    Y Okubo
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Japan
    Life Sci 70:325-36. 2001
  10. ncbi request reprint Effect of hyperbaric oxygenation on bone induced by recombinant human bone morphogenetic protein-2
    Y Okubo
    Graduate Student, Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto
    Br J Oral Maxillofac Surg 39:91-5. 2001

Collaborators

Detail Information

Publications53

  1. ncbi request reprint Bone induction by Escherichia coli -derived recombinant human bone morphogenetic protein-2 compared with Chinese hamster ovary cell-derived recombinant human bone morphogenetic protein-2
    K Bessho
    Assistant Professor, Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Br J Oral Maxillofac Surg 38:645-649. 2000
    ..Quantitative analysis indicated that the activity of ErhBMP-2 was similar to that of CrhBMP-2, so ErhBMP-2 may be useful for inducing bone formation...
  2. ncbi request reprint Osteoinduction by recombinant human bone morphogenetic protein-2 at intramuscular, intermuscular, subcutaneous and intrafatty sites
    Y Okubo
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Japan
    Int J Oral Maxillofac Surg 29:62-6. 2000
    ..Five microg of rhBMP-2, a relatively low dose, induced adequate new bone formation in all sites. The variations of osteoinductive activity of rhBMP-2 in various sites may be due to differences in the blood supply...
  3. pmc Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations
    Honoka Kiso
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Shogoin Kawahara cho, Sakyo ku, Kyoto, Japan
    PLoS ONE 9:e96938. 2014
    ..These results further suggest that the phenotypes of USAG-1 and BMP-7 mutant mice reported provide opportunities for regenerative medicine and dentistry. ..
  4. doi request reprint Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse
    Akiko Murashima-Suginami
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Shogoin Kawahara cho, Sakyo ku, Kyoto 606 8507, Japan
    Biochem Biophys Res Commun 369:1012-6. 2008
    ..Based upon these results, we conclude that enhanced BMP signaling results in supernumerary teeth and BMP signaling was modulated by Wnt signaling in the USAG-1 deficient mouse model...
  5. ncbi request reprint Osteoinduction by bone morphogenetic protein-2 via adenoviral vector under transient immunosuppression
    Y Okubo
    Graduate School of Medicine, Kyoto University, 54 Kawahara cho, Shogoin, Sakyo ku, Kyoto, 606 8507, Japan
    Biochem Biophys Res Commun 267:382-7. 2000
    ..The activity of osteoinduction in Group I was higher than that in Group II. These results suggest that gene therapy with AxCAOBMP-2 under transient immunosuppression may be useful for bone reconstruction...
  6. ncbi request reprint Effect of FK506 on osteoinduction by recombinant human bone morphogenetic protein-2
    Shinji Kaihara
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, 54 Kawahara cho, Shogoin, Sakyo ku, Japan
    Life Sci 72:247-56. 2002
    ..In order to use FK506 effectively for promoting bone growth, we must further examine the appropriate dose, method, and period of administration...
  7. pmc Simultaneous gene transfer of bone morphogenetic protein (BMP) -2 and BMP-7 by in vivo electroporation induces rapid bone formation and BMP-4 expression
    Mariko Kawai
    Department of Oral Morphology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700 8525, Japan
    BMC Musculoskelet Disord 7:62. 2006
    ..To promote enhanced osteoinduction using this method, we simultaneously transferred cDNAs for BMP-2 and BMP-7, as inserts in the non-viral vector pCAGGS...
  8. ncbi request reprint Osteoinduction by bone morphogenetic protein 2-expressing adenoviral vector: application of biomaterial to mask the host immune response
    Junya Sonobe
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606 8507, Japan
    Hum Gene Ther 15:659-68. 2004
    ..Immunohistochemical analysis on days 3 and 7 revealed decreased immunogenicity in the BMP group compared with the injection group. These findings suggested that collagen was an effective masking material for our vector...
  9. ncbi request reprint The time course study of osteoinduction by bone morphogenetic protein-2 via adenoviral vector
    Y Okubo
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Japan
    Life Sci 70:325-36. 2001
    ..These results suggest that gene therapy with AxCAOBMP-2 under transient immunosuppression may be useful for bone reconstruction...
  10. ncbi request reprint Effect of hyperbaric oxygenation on bone induced by recombinant human bone morphogenetic protein-2
    Y Okubo
    Graduate Student, Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto
    Br J Oral Maxillofac Surg 39:91-5. 2001
    ..These results suggest that HBO accelerated the activity and rate of osteoinduction by rhBM P-2...
  11. doi request reprint Experimental study of osteoinduction using a new material as a carrier for bone morphogenetic protein-2
    Noriaki Koyama
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, 54 Kawahara cho, Shogoin, Sakyo ku, Kyoto, Japan
    Br J Oral Maxillofac Surg 49:314-8. 2011
    ..Our results suggest that artificial collagen is useful as a carrier for rhBMP-2 designed to promote the formation of new bone...
  12. ncbi request reprint The effect of fibroblast growth factor-2 on the osteoinductive activity of recombinant human bone morphogenetic protein-2 in rat muscle
    Kazuma Fujimura
    Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Ishikawa pref 920 0293, Japan
    Arch Oral Biol 47:577-84. 2002
    ..These results show that combined treatment with FGF-2 and BMP-2 has a biphasic effect on osteoinductive activity, i.e. it increases with low doses of FGF-2 and decreases with high doses of FGF-2...
  13. ncbi request reprint In vitro and in vivo studies of a bone morphogenetic protein-2 expressing adenoviral vector
    Y Okubo
    Graduate School of Medicine, Kyoto University, Japan
    J Bone Joint Surg Am 83:S99-104. 2001
    ....
  14. pmc Risk factors and indices of osteomyelitis of the jaw in osteoporosis patients: results from a hospital-based cohort study in Japan
    Toru Yamazaki
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    PLoS ONE 8:e79376. 2013
    ..Here, we clarified risk factors of OMJ and evaluate the predictive accuracy of risk indices in osteoporosis patients...
  15. doi request reprint Pluripotency of mesenchymal cells derived from synovial fluid in patients with temporomandibular joint disorder
    Noriaki Koyama
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606 8507, Japan
    Life Sci 89:741-7. 2011
    ..The present study aimed at characterizing the phenotype and differentiation potential of adherent synovial fluid-derived cells from temporomandibular joint (TMJ) disorder patients...
  16. ncbi request reprint Ectopic bone formation by human bone morphogenetic protein-2 gene transfer to skeletal muscle using transcutaneous electroporation
    Mariko Kawai
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, 54 Kawahara cho, Shogoin, Sakyo ku, Kyoto 606 8507, Japan
    Hum Gene Ther 14:1547-56. 2003
    ..Thus, transcutaneous electroporation with pCAGGS-BMP-2 induced ectopic bone formation in the skeletal muscle of rats. This supports the possibility of applying human BMP-2 gene transfer using transcutaneous electroporation clinically...
  17. ncbi request reprint Over expression of bone morphogenetic protein-3b (BMP-3b) using an adenoviral vector promote the osteoblastic differentiation in C2C12 cells and augment the bone formation induced by bone morphogenetic protein-2 (BMP-2) in rats
    Shinji Kaihara
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, 54 Kawahara cho, Shogoin, Sakyo, Kyoto 606 8507, Japan
    Life Sci 72:1683-93. 2003
    ..When AxCAOBMP-2, AxCAKBMP-3b, and AxCAwt were injected into the calf muscles of nude rats (F 344/N Jcl-rnu), the osteoinduction seen with AxCAOBMP-2 and AxCAKBMP-3b was greater than that seen with AxCAOBMP-2 and AxCAwt...
  18. ncbi request reprint Preclinical study of recombinant human bone morphogenetic protein-2: application of hyperbaric oxygenation during bone formation under unfavourable condition
    Y Okubo
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Shogoin, Japan
    Int J Oral Maxillofac Surg 32:313-7. 2003
    ..Hyperbaric oxygenation therapy may increase the clinical application of rhBMP-2 to unfavourable condition...
  19. ncbi request reprint Effect of elcatonin on osteoinduction by recombinant human bone morphogenetic protein-2
    Y Okubo
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, 54 Kawahara cho, Shogoin, Sakyo ku, Kyoto, 606 8507, Japan
    Biochem Biophys Res Commun 269:317-21. 2000
    ..These results suggested that elcatonin is effective in enhancing osteoinduction by rhBMP-2 within the dose range of this study, and that elcatonin has an anabolic effect on osteoblasts in addition to an antiresorptive effect...
  20. pmc Effects of Usag-1 and Bmp7 deficiencies on murine tooth morphogenesis
    Kazuyuki Saito
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Shogoin kawahara cho 54, Sakyo ku, Kyoto, 606 8397, Japan
    BMC Dev Biol 16:14. 2016
    ..In this study, we established double genetically modified mice to examine the in vivo inter-relationships between Bmp7 and Usag-1...
  21. ncbi request reprint Simple and effective osteoinductive gene therapy by local injection of a bone morphogenetic protein-2-expressing recombinant adenoviral vector and FK506 mixture in rats
    S Kaihara
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Shogoin, Sakyo ku, Kyoto, Japan
    Gene Ther 11:439-47. 2004
    ..These results indicate that coinjection of FK506 significantly promotes osteoinduction. In addition, local injection of FK506 may also make it possible to prevent a decrease of gene expression with other adenoviral vector...
  22. ncbi request reprint Regeneration of articular cartilage defects in the temporomandibular joint of rabbits by fibroblast growth factor-2: a pilot study
    H Takafuji
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, 54 Syogoin, Kawahara cho, Sakyo ku, Kyoto shi 606 8507, Japan
    Int J Oral Maxillofac Surg 36:934-7. 2007
    ..The present results suggest that an optimum concentration of FGF-2 could restore defects of TMJ articular cartilage clinically...
  23. doi request reprint Id2 controls chondrogenesis acting downstream of BMP signaling during maxillary morphogenesis
    Tomoko Sakata-Goto
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Japan
    Bone 50:69-78. 2012
    ..As a consequence, abnormal endochondral ossification was observed in cranial base synchondroses during the postnatal growth period, resulting in the clinical phenotype of maxillofacial dysmorphogenesis...
  24. pmc Increased risk of temporomandibular joint closed lock: a case-control study of ANKH polymorphisms
    Boyen Huang
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    PLoS ONE 6:e25503. 2011
    ....
  25. doi request reprint Evaluation of pluripotency in human dental pulp cells
    Noriaki Koyama
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Shogoin, Sakyo ku, Kyoto, Japan
    J Oral Maxillofac Surg 67:501-6. 2009
    ..Postnatal stem cells have been isolated from a variety of tissues. Previously, it was generally accepted that the differentiation potential of postnatal stem cells was lineage restricted...
  26. pmc Antagonistic Functions of USAG-1 and RUNX2 during Tooth Development
    Yumiko Togo
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara cho, Sakyo ku, 606 8507, Kyoto, Japan
    PLoS ONE 11:e0161067. 2016
    ..We hypothesize that RUNX2 inhibits the bone morphogenetic protein (BMP) and/or Wnt signaling pathways regulated by USAG-1, whereas RUNX2 expression is induced by BMP signaling independently of USAG-1. ..
  27. doi request reprint The Local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth
    Kazumasa Nakao
    Department of Oral and Maxillofacial Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara cho, Shogo in, Sakyo ku, Kyoto 606 8507, Japan
    Sci Rep 5:10554. 2015
    ..The local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth and might further affect mortality via unknown mechanisms. ..
  28. doi request reprint Osteoinduction by repeat plasmid injection of human bone morphogenetic protein-2
    Kenji Osawa
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Sakyo ku, Kyoto, Japan
    J Gene Med 12:937-44. 2010
    ..On the other hand, plasmid-based gene transfer is a safe method and can be harnessed for practical applications...
  29. pmc Prospective signs of cleidocranial dysplasia in Cebpb deficiency
    Boyen Huang
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Shogoin kawahara cho 54, Sakyo ku, Kyoto 606 8507, Japan
    J Biomed Sci 21:44. 2014
    ..Masseter and temporal muscles were collected and weighed. Expression of Cebpb was examined with a reverse transcriptase polymerase chain reaction (RT-PCR) technique...
  30. doi request reprint Evaluation of tongue sensory disturbance by somatosensory evoked magnetic fields following tongue stimulation
    Hitoshi Maezawa
    Human Brain Research Center, Graduate School of Medicine, Kyoto University, Sakyo ku, Kyoto 606 8507, Japan
    Neurosci Res 71:244-50. 2011
    ..The test sensitivity and specificity of the procedure were 92.3% and 100%, respectively. Tongue SEFs are reproducible and objective method to evaluate sensory disturbance of the tongue...
  31. doi request reprint Osteoinduction by microbubble-enhanced transcutaneous sonoporation of human bone morphogenetic protein-2
    Kenji Osawa
    Department of Oral and Maxillofacial Surgery, Kyoto University, Japan
    J Gene Med 11:633-41. 2009
    ..Viral vector-mediated gene transfer is efficient, but safety concerns prevent its clinical application for common diseases. Sonoporation is a simple and inexpensive method that only requires a plasmid and a sonoporation device...
  32. ncbi request reprint Regeneration of defects in the articular cartilage in rabbit temporomandibular joints by bone morphogenetic protein-2
    T Suzuki
    Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Ishikawa, Japan
    Br J Oral Maxillofac Surg 40:201-6. 2002
    ..However, this study supports the contention that BMP-2 may be useful in the regeneration of cartilage in TMJ disease...
  33. pmc The increase in prescriptions of bisphosphonates and the incidence proportion of osteonecrosis of the jaw after risk communication activities in Japan: a hospital-based cohort study
    Eriko Sumi
    Department of Clinical Innovative Medicine, Institute for Advancement of Clinical and Translational Science, Kyoto University, Kyoto, Japan
    Pharmacoepidemiol Drug Saf 23:398-405. 2014
    ....
  34. pmc Mastication and risk for diabetes in a Japanese population: a cross-sectional study
    Toru Yamazaki
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    PLoS ONE 8:e64113. 2013
    ..Our objective was to examine the association between mastication, namely masticatory performance or rate of eating, and diabetes in a population-based cohort...
  35. doi request reprint Human induced pluripotent stem cells differentiated into chondrogenic lineage via generation of mesenchymal progenitor cells
    Noriaki Koyama
    Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Stem Cells Dev 22:102-13. 2013
    ..Our study demonstrates that hiPSCs can be efficiently differentiated into the chondrogenic lineage in vitro via generation of mesenchymal progenitor cells, using a simplified, multistep culture method...
  36. ncbi request reprint A bioactive bone cement containing Bis-GMA resin and A-W glass-ceramic as an augmentation graft material on mandibular bone
    Kazuma Fujimura
    Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Ishikawa, Japan
    Clin Oral Implants Res 14:659-67. 2003
    ..The results suggest that the BABC has good handling properties, a high bonding strength and good biocompatibility, and that it has potential for clinical application as a substitute material for autogenous bone transplantation...
  37. ncbi request reprint Expression of bone morphogenetic protein in the course of osteoinduction by recombinant human bone morphogenetic protein-2
    Yasunori Okubo
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Shogoin, Japan
    Clin Oral Implants Res 13:80-5. 2002
    ..These results indicate that the woven bone was replaced with mature lamellar bone from day 14 to day 21. The present findings suggest that rhBMP-2 plays an important role in osteoinduction, especially at the early stage...
  38. doi request reprint Magnesium calcium phosphate as a novel component enhances mechanical/physical properties of gelatin scaffold and osteogenic differentiation of bone marrow mesenchymal stem cells
    Ahmed Hussain
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Tissue Eng Part A 18:768-74. 2012
    ....
  39. doi request reprint Magnesium calcium phosphate/β-tricalcium phosphate incorporation into gelatin scaffold: an in vitro comparative study
    Ahmed Hussain
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Japan
    J Tissue Eng Regen Med 8:919-24. 2014
    ..These findings indicate that MSCs seeded in scaffolds incorporating MCP showed significantly superior biological results in terms of proliferation and osteogenic differentiation in comparison with other scaffold types...
  40. ncbi request reprint Recent Clinical Evidence in Bisphosphonate-related Osteomyelitis of the Jaw: Focus on Risk, Prevention and Treatment
    Toru Yamazaki
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara cho, Sakyo ku, Kyoto 606 8507, Japan
    Rev Recent Clin Trials 9:37-52. 2014
    ..In particular, we reconsider the definition of BRONJ from the standpoint of clinical evidence. Finally, we propose a new strategy for the treatment of BROMJ. ..
  41. pmc Periodontitis and Porphyromonas gingivalis in preclinical stage of arthritis patients
    Motomu Hashimoto
    Department of the Control for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    PLoS ONE 10:e0122121. 2015
    ..To determine whether the presence of periodontitis (PD) and Porphyromonas gingivalis (Pg) in the subgingival biofilm associates with the development of rheumatoid arthritis (RA) in treatment naïve preclinical stage of arthritis patients...
  42. pmc Accelerators of osteogenesis by recombinant human bone morphogenetic protein-2
    Yasunori Okubo
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, 54 Kawahara cho, Shogoin, Sakyo ku, Kyoto, 606 8507, Japan
    Drug Target Insights 2:55-60. 2007
    ..These results suggest that bFGF, FK506, elcatonin, and HBO accelerated the activity and rate of osteoinduction by rhBMP2. These results may be useful when BMP is applied clinically in near future...
  43. ncbi request reprint Rudiment incisors survive and erupt as supernumerary teeth as a result of USAG-1 abrogation
    Akiko Murashima-Suginami
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606 8507, Japan
    Biochem Biophys Res Commun 359:549-55. 2007
    ..USAG-1 abrogation rescued apoptotic elimination of odontogenic mesenchymal cells. Based upon these results, we conclude that USAG-1 controls the number of teeth in the maxillary incisor region by regulating apoptosis...
  44. doi request reprint Impact of different surgery modalities to correct class III jaw deformities on the pharyngeal airway space
    Tarek Elsayed Ftohy Abdelrahman
    Department of Oral and Maxillofacial Surgery and Oral and Maxillofacial Surgery, Kyoto University, Kyoto, Japan
    J Craniofac Surg 22:1598-601. 2011
    ....
  45. ncbi request reprint Effectiveness of kampo medicine (sai-boku-to) in treatment of patients with glossodynia
    K Bessho
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Japan
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 86:682-6. 1998
    ..The purpose of this study was to evaluate the usefulness of a Kampo medicine (Sai-boku-to) for treatment of patients with glossodynia...
  46. ncbi request reprint Visualization of IP(3) dynamics reveals a novel AMPA receptor-triggered IP(3) production pathway mediated by voltage-dependent Ca(2+) influx in Purkinje cells
    Y Okubo
    Department of Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Neuron 32:113-22. 2001
    ..These results revealed a novel IP(3) signaling pathway in Purkinje cells that can be elicited by synaptic inputs from climbing fibers...
  47. ncbi request reprint Dental trauma related to general anesthesia: should the anesthesiologist perform a preanesthetic dental evaluation?
    Saeed Riad Idrees
    Department of Oral and Maxillofacial Surgery Graduate School of Medicine, Kyoto University, 54 Kawahara cho, Shogoin, Sakyo ku, Kyoto 606 8507, Japan, Tel 81 75 751 3401, Fax 81 75 761 9732 e mail
    Oral Health Dent Manag 13:271-4. 2014
    ..Preoperative notes should record any damages or missing teeth. In addition, anesthesiologists must take adequate intraprocedure precautions to prevent/minimize iatrogenic dental injury...
  48. doi request reprint Somatosensory evoked magnetic fields following electric tongue stimulation using pin electrodes
    Hitoshi Maezawa
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Sakyo ku, Kyoto 606 8507, Japan
    Neurosci Res 62:131-9. 2008
    ..92 and 10.99+/-8.98 fT/cm, respectively, and the mean laterality index, expressed by [(left-right)/(left+right)] was 0.025+/-0.104. This parameter can be useful for evaluating patients with unilateral sensory abnormality of the tongue...
  49. ncbi request reprint Langerhans' cell histiocytosis confined to the jaw
    Shinichiro Nakamura
    Kyoto Oral health care center, Rakuwaki Otowa Hospital, Kyoto, Japan
    J Oral Maxillofac Surg 63:989-95. 2005
  50. ncbi request reprint Runx3 expression during mouse tongue and palate development
    Hiromitsu Yamamoto
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Anat Rec A Discov Mol Cell Evol Biol 288:695-9. 2006
    ..5 to 16.5. The functional relationship between Runx3 and TGF-beta/BMPs signaling in tongue and palate development is discussed...
  51. doi request reprint Social nicotine dependence in Australian dental undergraduate students
    Boyen Huang
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Int Dent J 61:152-6. 2011
    ..A special interest was to identify the role of factors such as age, gender, year of dental education and cohabitants' smoking status for social nicotine dependence...
  52. doi request reprint Posttraumatic temporomandibular joint ankylosis in adults: is it mandatory to perform interposition arthroplasty?
    Tarek Ftohy Abdelrahman
    Department of Oral and Maxillofacial Surgery, Kyoto University, Kyoto 606 8507, Japan
    J Craniofac Surg 21:1301-4. 2010
    ..The outcome of the patient's treatment was satisfactory. Wide gap arthroplasty if followed by vigorous physiotherapy may be sufficient in treating TMJ ankylosis and prevent recurrence in adults...
  53. doi request reprint Risk of osteomyelitis of the jaw induced by oral bisphosphonates in patients taking medications for osteoporosis: a hospital-based cohort study in Japan
    Toru Yamazaki
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, 54, Shogoin Kawahara cho, Kyoto 606 8507, Japan
    Bone 51:882-7. 2012
    ..However, oral BPs may increase the risk of OMJ compared with patients treated with other osteoporosis medications and the risk of side effects should be kept in mind...