H Kanazawa

Summary

Affiliation: Kyoritsu College of Pharmacy
Country: Japan

Publications

  1. ncbi Temperature-responsive chromatographic separation of amino acid phenylthiohydantions using aqueous media as the mobile phase
    H Kanazawa
    Kyoritsu College of Pharmacy, Minato, Tokyo, Japan
    Anal Chem 72:5961-6. 2000
  2. ncbi Stereospecific analysis of omeprazole in human plasma as a probe for CYP2C19 phenotype
    Hideko Kanazawa
    Department of Physical Chemistry, Kyoritsu College of Pharmacy, Shibakoen 1 5 30, Minato ku, Tokyo 105 8512, Japan
    J Pharm Biomed Anal 30:1817-24. 2003
  3. ncbi Stereospecific analysis of loxoprofen in plasma by chiral column liquid chromatography with a circular dichroism-based detector
    Hideko Kanazawa
    Kyoritsu College of Pharmacy, Shibakoen 1 5 30, Minato ku, Tokyo 105 8512, Japan
    J Chromatogr A 948:303-8. 2002
  4. ncbi Determination of midazolam and its metabolite as a probe for cytochrome P450 3A4 phenotype by liquid chromatography-mass spectrometry
    Hideko Kanazawa
    Department of Physical Chemistry, Kyoritsu College of Pharmacy, 1 5 30 Shibakoen, Minato ku, Tokyo 105 8512, Japan
    J Chromatogr A 1031:213-8. 2004
  5. ncbi Temperature-responsive polymers for liquid-phase separations
    Hideko Kanazawa
    Department of Physical Pharmaceutical Chemistry, Kyoritsu College of Pharmacy, Minatoku, Tokyo, Japan
    Anal Bioanal Chem 378:46-8. 2004
  6. ncbi Thermally responsive chromatographic materials using functional polymers
    Hideko Kanazawa
    Department of Physical Pharmaceutical Chemistry, Kyoritsu University of Pharmacy, Tokyo, Japan
    J Sep Sci 30:1646-56. 2007
  7. ncbi Determination of omeprazole and its metabolites in human plasma by liquid chromatography-mass spectrometry
    Hideko Kanazawa
    Kyoritsu College of Pharmacy, Tokyo, Japan
    J Chromatogr A 949:1-9. 2002
  8. doi Aqueous chromatographic system for separation of biomolecules using thermoresponsive polymer modified stationary phase
    Hideko Kanazawa
    Department of Physical Pharmaceutical Chemistry, Kyoritsu University of Pharmacy, 1 5 30 Shibakoen, Minato ku, Tokyo 105 8512, Japan
    J Chromatogr A 1191:157-61. 2008
  9. ncbi Temperature-responsive stationary phase utilizing a polymer of proline derivative for hydrophobic interaction chromatography using an aqueous mobile phase
    Hideko Kanazawa
    Department of Physical Pharmaceutical Chemistry, Kyoritsu University of Pharmacy, 1 5 30 Shibakoen, Tokyo 105 8512, Japan
    J Chromatogr A 1106:152-8. 2006
  10. ncbi Stereospecific analysis of lorazepam in plasma by chiral column chromatography with a circular dichroism-based detector
    H Kanazawa
    Kyoritsu College of Pharmacy, Tokyo, Japan
    J Chromatogr A 871:181-8. 2000

Collaborators

Detail Information

Publications41

  1. ncbi Temperature-responsive chromatographic separation of amino acid phenylthiohydantions using aqueous media as the mobile phase
    H Kanazawa
    Kyoritsu College of Pharmacy, Minato, Tokyo, Japan
    Anal Chem 72:5961-6. 2000
    ..The method is useful for various separations in life science so that proteins can maintain their biological activity and enzymes, their enzymatic activity...
  2. ncbi Stereospecific analysis of omeprazole in human plasma as a probe for CYP2C19 phenotype
    Hideko Kanazawa
    Department of Physical Chemistry, Kyoritsu College of Pharmacy, Shibakoen 1 5 30, Minato ku, Tokyo 105 8512, Japan
    J Pharm Biomed Anal 30:1817-24. 2003
    ..5 h after drug intake. The present study is useful because of the part polymorphism plays in the therapeutic effectiveness of proton pump inhibitors during the treatment of acid-related diseases...
  3. ncbi Stereospecific analysis of loxoprofen in plasma by chiral column liquid chromatography with a circular dichroism-based detector
    Hideko Kanazawa
    Kyoritsu College of Pharmacy, Shibakoen 1 5 30, Minato ku, Tokyo 105 8512, Japan
    J Chromatogr A 948:303-8. 2002
    ....
  4. ncbi Determination of midazolam and its metabolite as a probe for cytochrome P450 3A4 phenotype by liquid chromatography-mass spectrometry
    Hideko Kanazawa
    Department of Physical Chemistry, Kyoritsu College of Pharmacy, 1 5 30 Shibakoen, Minato ku, Tokyo 105 8512, Japan
    J Chromatogr A 1031:213-8. 2004
    ..We also investigated the effect of propofol on the metabolism of midazolam using recombinant CYP3A4. Propofol competitively inhibited the metabolism of midazolam to 1'-hydroxymidazolam by CYP3A4...
  5. ncbi Temperature-responsive polymers for liquid-phase separations
    Hideko Kanazawa
    Department of Physical Pharmaceutical Chemistry, Kyoritsu College of Pharmacy, Minatoku, Tokyo, Japan
    Anal Bioanal Chem 378:46-8. 2004
  6. ncbi Thermally responsive chromatographic materials using functional polymers
    Hideko Kanazawa
    Department of Physical Pharmaceutical Chemistry, Kyoritsu University of Pharmacy, Tokyo, Japan
    J Sep Sci 30:1646-56. 2007
    ..Applications of thermally responsive columns for separations in the HPLC mode are demonstrated...
  7. ncbi Determination of omeprazole and its metabolites in human plasma by liquid chromatography-mass spectrometry
    Hideko Kanazawa
    Kyoritsu College of Pharmacy, Tokyo, Japan
    J Chromatogr A 949:1-9. 2002
    ..In the mass spectrum, the molecular ions of omeprazole, hydroxyomeprazole and omeprazole sulfone were clearly observed as base peaks. This method is sufficiently sensitive and accurate for pharmacokinetic studies of omeprazol...
  8. doi Aqueous chromatographic system for separation of biomolecules using thermoresponsive polymer modified stationary phase
    Hideko Kanazawa
    Department of Physical Pharmaceutical Chemistry, Kyoritsu University of Pharmacy, 1 5 30 Shibakoen, Minato ku, Tokyo 105 8512, Japan
    J Chromatogr A 1191:157-61. 2008
    ..The electrostatic and hydrophobic interactions could be modulated simultaneously with the temperature in an aqueous mobile phase, thus the separation system would have potential applications in the separation of biomolecules...
  9. ncbi Temperature-responsive stationary phase utilizing a polymer of proline derivative for hydrophobic interaction chromatography using an aqueous mobile phase
    Hideko Kanazawa
    Department of Physical Pharmaceutical Chemistry, Kyoritsu University of Pharmacy, 1 5 30 Shibakoen, Tokyo 105 8512, Japan
    J Chromatogr A 1106:152-8. 2006
    ..In contrast to a PNIPAAm-modified surface, a poly(acryloyl-L-proline methyl ester)-modified surface showed a greater affinity for hydrophobic amino acids...
  10. ncbi Stereospecific analysis of lorazepam in plasma by chiral column chromatography with a circular dichroism-based detector
    H Kanazawa
    Kyoritsu College of Pharmacy, Tokyo, Japan
    J Chromatogr A 871:181-8. 2000
    ..Chiroptical detection is useful for the pharmacokinetic study of chiral drugs...
  11. ncbi Determination of alpha-tocopherol and alpha-tocopherylquinone in rat tissues and plasma by high-performance liquid chromatography with electrochemical detection
    H Kanazawa
    Kyoritsu College of Pharmacy, Tokyo, Japan
    Chem Pharm Bull (Tokyo) 48:1462-6. 2000
    ..The technique is particularly useful in the quantitation of the oxidation of alpha-tocopherol in biological samples...
  12. ncbi Aqueous chromatography system using temperature-responsive polymer-modified stationary phases
    Eri Ayano
    Department of Physical Pharmaceutical Chemistry, Kyoritsu University of Pharmacy, Tokyo, Japan
    J Sep Sci 29:738-49. 2006
    ..This analytical system reduces organic waste because no organic solvent is used to separate the solutes and can therefore be classified as environmentally friendly. Future medical and pharmaceutical applications are expected...
  13. ncbi Determination of sedatives and anesthetics in plasma by liquid chromatography-mass spectrometry with a desalting system
    H Kanazawa
    Kyoritsu College of Pharmacy, Tokyo, Japan
    J Chromatogr A 797:227-36. 1998
    ..The chiral separation of lorazepam was achieved on a chiral column with UV, optical rotatory detection and MS. This method is sufficiently sensitive and accurate for the pharmacokinetic studies of these drugs in biological samples...
  14. ncbi Separation of nucleotides with an aqueous mobile phase using pH- and temperature-responsive polymer modified packing materials
    Eri Ayano
    Department of Physical Pharmaceutical Chemistry, Kyoritsu University of Pharmacy, Minato, Tokyo, Japan
    Anal Sci 22:539-43. 2006
    ..A pH- and temperature-responsive chromatography would be greatly useful for biopolymer and nucleotide separation and purification...
  15. ncbi Aqueous chromatography system using pH- and temperature-responsive stationary phase with ion-exchange groups
    Eri Ayano
    Department of Physical Pharmaceutical Chemistry, Kyoritsu University of Pharmacy, Minato ku, Tokyo, Japan
    J Chromatogr A 1119:58-65. 2006
    ..PH- and temperature-responsive chromatography is expected to be useful for the separation of pharmaceuticals and biomolecules...
  16. doi Thermo-responsive polymer brush-grafted porous polystyrene beads for all-aqueous chromatography
    Aya Mizutani
    Graduate School of Pharmaceutical Sciences, Keio University, 1 5 14 Shibakoen, Minato, Tokyo 105 0011, Japan
    J Chromatogr A 1217:522-9. 2010
    ..These results indicated that PIPAAm brush-grafted porous polystyrene beads prepared by surface-initiated ATRP was effective stationary phase of thermo-responsive chromatography for aqueous phase peptide separations...
  17. doi Aqueous chromatographic system for the quantification of propofol in biological fluids using a temperature-responsive polymer modified stationary phase
    Tadashi Nishio
    Faculty of Pharmacy, Keio University, 1 5 30, Shibakoen, Minato ku, Tokyo 105 8512, Japan
    J Chromatogr A 1216:7427-32. 2009
    ..In addition, by using water instead of fossil fuel, it is the ideal analytical method according to green chemistry...
  18. ncbi Interfacial property modulation of thermoresponsive polymer brush surfaces and their interaction with biomolecules
    Kenichi Nagase
    Institute of Advanced Biomedical Engineering and Science, Tokyo Women s Medical University, Kawadacho, Shinjuku, Tokyo, Japan
    Langmuir 23:9409-15. 2007
    ....
  19. ncbi Temperature-responsive chromatography using poly(N-isopropylacrylamide) hydrogel-modified silica
    Hideko Kanazawa
    Kyoritsu College of Pharmacy, Minato, Tokyo, Japan
    Anal Sci 18:45-8. 2002
    ..A temperature-responsive elution behavior was observed on the separation of steroids and PTH-amino acids. The method is expected to be applicable to separation in the pharmaceutical and biomedical fields...
  20. ncbi Temperature- and pH-responsive aminopropyl-silica ion-exchange columns grafted with copolymers of N-isopropylacrylamide
    Chikako Sakamoto
    Department of Physical Chemistry, Kyoritsu College of Pharmacy, 1 5 30 Shibakoen, Minato ku, Tokyo 105 8512, Japan
    J Chromatogr A 1030:247-53. 2004
    ..Environmentally-responsive chromatography is expected to be applicable to the separation of pharmaceuticals and biomolecules, such as peptides, proteins and nucleic acids...
  21. doi Total internal biliary diversion during liver transplantation for type 1 progressive familial intrahepatic cholestasis: a novel approach
    V P Mali
    Organ Transplantation Center, National Center for Child Health and Development, Tokyo, Japan
    Pediatr Transplant 20:981-986. 2016
    ..TIBD during LT may be a clinically effective stoma-free biliary diversion and may prevent recurrent graft steatosis following LT for PFIC type 1...
  22. doi Rewarming preservation by organ perfusion system for donation after cardiac death liver grafts in pigs
    N Matsuno
    National Center for Child Health and Development, Tokyo, Japan Tokyo Metropolitan University, Mechanical Engineering, Tokyo, Japan Electronic address
    Transplant Proc 46:1095-8. 2014
    ..However, this requires the development of novel preservation methods to recover the organ from changes due to warm ischemia time (WIT)...
  23. ncbi Determination of peptides by high-performance liquid chromatography with laser-induced fluorescence detection
    H Kanazawa
    Kyoritsu College of Pharmacy, Tokyo, Japan
    J Chromatogr A 763:23-9. 1997
    ..The method was sensitive enough to permit the quantitative determination of opioid peptides and bradykinin in tissue and plasma samples...
  24. doi Effective separation of peptides using highly dense thermo-responsive polymer brush-grafted porous polystyrene beads
    Aya Mizutani
    Graduate School of Pharmaceutical Sciences, Keio University, 1 5 14 Shibakoen, Minato, Tokyo 105 0011, Japan
    J Chromatogr B Analyt Technol Biomed Life Sci 878:2191-8. 2010
    ..These results indicated that the prepared beads with grafted PIPAAm nearby the outer surface became an effective chromatographic stationary phase for retaining basic peptides using wide pH range of mobile phase...
  25. ncbi Determination of theophylline and its metabolites in biological samples by liquid chromatography-mass spectrometry
    H Kanazawa
    Kyoritsu College of Pharmacy, Minato, Tokyo, Japan
    J Chromatogr A 870:87-96. 2000
    ..In the mass spectrum, the molecular ions of these drugs and metabolites were clearly observed as base peaks. This method is sufficiently sensitive and accurate for the pharmacokinetic studies of these drugs...
  26. ncbi Products of the reaction between alpha- or gamma-tocopherol and nitrogen oxides analyzed by high-performance liquid chromatography with UV-visible and atmospheric pressure chemical ionization mass spectrometric detection
    Yoshiko Nagata
    Department of Physical Chemistry, Kyoritsu University of Pharmacy, 1 5 30 Shibakoen, Minato ku, Tokyo 105 8512, Japan
    J Chromatogr A 1036:177-82. 2004
    ....
  27. ncbi Study of temperature-responsibility on the surfaces of a thermo-responsive polymer modified stationary phase
    Eri Ayano
    Department of Physical Pharmaceutical Chemistry, Kyoritsu University of Pharmacy, Minato ku, Tokyo, Japan
    J Chromatogr A 1119:51-7. 2006
    ..This system should be highly useful to control the function and property of the stationary phase for HPLC only by changing the temperature with an aqueous solvent...
  28. doi Preparation of thermo-responsive polymer brushes on hydrophilic polymeric beads by surface-initiated atom transfer radical polymerization for a highly resolutive separation of peptides
    Aya Mizutani
    Graduate School of Pharmaceutical Sciences, Keio University, 1 5 14 Shibakoen, Minato, Tokyo 105 0011, Japan
    J Chromatogr A 1217:5978-85. 2010
    ..0 m(2)/g by nitrogen gas adsorption method. Copolymer brush of P(IPAAm-co-tBAAm) grafted PHMA beads improved the stationary phase of thermo-responsive chromatography for the all-aqueous separation of peptides and proteins...
  29. ncbi Analysis of melatonin using a pH- and temperature-responsive aqueous chromatography system
    Eri Ayano
    Department of Physical Pharmaceutical Chemistry, Kyoritsu University of Pharmacy, Tokyo, Japan
    J Chromatogr A 1156:213-9. 2007
    ..A pH- and temperature-responsive chromatography is expected to be useful for the separation of pharmaceuticals and biomolecules...
  30. doi Impact of rewarming preservation by continuous machine perfusion: improved post-transplant recovery in pigs
    T Shigeta
    National Center for Child Health and Development, Transplantation Center, Division for Advanced Medical Sciences, Tokyo, Japan
    Transplant Proc 45:1684-9. 2013
    ..However, implementation of such a strategy requires the development of novel preservation methods to achieve recovery from changes owing to warm ischemia...
  31. ncbi Chiral separation and quantitation of pentazocine enantiomers in pharmaceuticals by capillary zone electrophoresis using maltodextrins
    T Watanabe
    Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences, Hoshi University, Tokyo, Japan
    J Pharm Biomed Anal 21:75-81. 1999
    ..The detection limit of pentazocine enantiomers was 29 pg, and the recoveries of(-)- and (+)-pentazocine were 98.9 (R.S.D., 3.4%) and 101.4% (R.S.D., 4.3%) with 10 microg/ml(-1), respectively...
  32. ncbi Dual temperature- and pH-responsive fluorescence molecular probe for cellular imaging utilizing a PNIPAAm-fluorescein copolymer
    Hiroki Kobayashi
    Faculty of Pharmacy, Keio University, Minato, Tokyo, Japan
    Anal Sci 25:1043-7. 2009
    ..Additionally, the cellular uptake in RAW264.7 cells of poly(NIPAAm-co-FL) conjugated with lipid was studied using a confocal laser scanning microscope...
  33. doi Polymeric nanoparticles encapsulating betamethasone phosphate with different release profiles and stealthiness
    Tsutomu Ishihara
    Institute of Drug Delivery Systems, Research Center for Medical Sciences, The Jikei University School of Medicine, 3 25 8 Nishi shimbashi, Minato ku, Tokyo 105 8461, Japan
    Int J Pharm 375:148-54. 2009
    ..This is the first study to systematically design and characterize biodegradable PLA/PLGA and PEG-PLA/PLGA-blended nanoparticles encapsulating BP with different release profiles and stealthiness...
  34. doi Efficient entrapment of poorly water-soluble pharmaceuticals in hybrid nanoparticles
    Tsutomu Ishihara
    DDS Institute, The Jikei University School of Medicine, 3 25 8 Nishi shinbashi, Minato, Tokyo 105 8461, Japan
    J Pharm Sci 98:2357-63. 2009
    ..These results suggested that such hybrid nanoparticles may be used to expand the availability of poorly water-soluble drugs for various therapeutic applications...
  35. doi Preparation of thermoresponsive polymer brush surfaces and their interaction with cells
    Aya Mizutani
    Department of Pharmacy, Kyoritsu University of Pharmacy, 1 5 14 Shibakoen, Minato, Tokyo 105 0011, Japan
    Biomaterials 29:2073-81. 2008
    ..Thermoresponsive surfaces prepared by surface-initiated ATRP techniques allow surface selection in preparing cell sheets from attachment-dependent cells having relatively strong adhesive property for tissue engineering applications...
  36. doi Influence of graft interface polarity on hydration/dehydration of grafted thermoresponsive polymer brushes and steroid separation using all-aqueous chromatography
    Kenichi Nagase
    Institute of Advanced Biomedical Engineering and Science, Tokyo Women s Medical University, 8 1 Kawadacho, Shinjuku, Tokyo 162 8666, Japan
    Langmuir 24:10981-7. 2008
    ....
  37. doi Preparation of thermoresponsive cationic copolymer brush surfaces and application of the surface to separation of biomolecules
    Kenichi Nagase
    Institute of Advanced Biomedical Engineering and Science, Tokyo Women s Medical University, 8 1 Kawadacho, Shinjuku, Tokyo 162 8666, Japan
    Biomacromolecules 9:1340-7. 2008
    ..These results indicate that cationic copolymer brush surfaces prepared by ATRP can rapidly alter their electrostatic properties by changing aqueous temperature...
  38. ncbi Effects of graft densities and chain lengths on separation of bioactive compounds by nanolayered thermoresponsive polymer brush surfaces
    Kenichi Nagase
    Institute of Advanced Biomedical Engineering and Science, Tokyo Women s Medical University, 8 1 Kawadacho, Shinjuku, Tokyo 162 8666, Japan
    Langmuir 24:511-7. 2008
    ....
  39. ncbi Electron-transfer mechanism in radical-scavenging reactions by a vitamin E model in a protic medium
    Ikuo Nakanishi
    Redox Regulation Research Group, Research Center for Radiation Safety, National Institute of Radiological Sciences, Inage Ku, Chiba 263 8555, Japan
    Org Biomol Chem 3:626-9. 2005
    ..63 V vs. SCE), due to strong solvation as compared to that in MeCN (0.97 V vs. SCE), may result in change of the radical-scavenging mechanisms between protic and aprotic media...
  40. ncbi A developed determination of midazolam and 1'-hydroxymidazolam in plasma by liquid chromatography-mass spectrometry: application of human pharmacokinetic study for measurement of CYP3A activity
    Mikiko Shimizu
    Department of Clinical Pharmacology, Hirosaki University School of Medicine, Hirosaki 036 8562, Japan
    J Chromatogr B Analyt Technol Biomed Life Sci 847:275-81. 2007
    ....
  41. ncbi Analysis of herbicides in water using temperature-responsive chromatography and an aqueous mobile phase
    Eri Ayano
    National Institute of Health Sciences, 1 18 1 Kamiyoga, Setagaya Ku, Tokyo 158 8501, Japan
    J Chromatogr A 1069:281-5. 2005
    ..The limits of quantitation (LOQ) of the eight herbicides were between 1 and 4 microg l(-1)...