Kinki University

Summary

Organization: Kinki University
Country: Japan

Top Publications

  1. ncbi Touch preparation of primary uterine pleomorphic rhabdomyosarcoma: report of a case with clinical cytopathologic features
    Yoh Watanabe
    Department of Obstetrics and Gynecology, Kinki University Faculty of Medicine, 377 2 Ohno Higashi, Osakasayama, Osaka 589 8511, Japan
    Acta Cytol 54:1027-30. 2010
  2. ncbi Biomechanical response of collagen fascicles to restressing after stress deprivation during culture
    Ei Yamamoto
    Biomechanics Laboratory, Department of Mechanical Engineering and Biomimetics, School of Biology Oriented Science and Technology, Kinki University, Kinokawa, Wakayama 649 6493, Japan
    J Biomech 40:2063-70. 2007
  3. ncbi Effects of some beta-adrenoceptor antagonists on orthostatic hypotension in repeatedly cold- (SART-) stressed rats
    Yoshinori Funakami
    Department of Pharmacology, Faculty of Pharmacy, Kinki University, Higashi Osaka, Japan
    Biol Pharm Bull 30:303-8. 2007
  4. ncbi Survey on cellular phone usage on students in Thailand
    Naohito Kawasaki
    School of Pharmacy, Kinki University, Kowake, Higashi Osaka, Osaka, Japan
    J Physiol Anthropol 25:377-82. 2006
  5. ncbi A new ultrasonographic technique for diagnosing deep venous insufficiency--imaging and functional evaluation of venous valves by ultrasonography with improved resolution
    Atsushi Kotani
    Department of Clinical Laboratory, Kinki University Hospital, 377 2, Ohnohigashi, Osakasayama, Osaka, 589 8511 Japan
    Int J Cardiovasc Imaging 23:493-500. 2007
  6. ncbi Suppression of MeIQ-induced SOS response by allylbenzenes from Asiasarum heterotropoides in the Salmonella typhimurium OY1001/1A2 umu test
    Mitsuo Miyazawa
    Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Higashiosaka shi, Osaka 577 8502, Japan
    Nat Prod Res 20:671-5. 2006
  7. ncbi Allergic contact dermatitis mimicking atopic dermatitis due to enoxolone in a topical medicament
    Naoki Oiso
    Department of Dermatology, Kinki University School of Medicine, 377 2 Ohno Higashi, Osaka Sayama, Osaka 589 8511, Japan
    Contact Dermatitis 54:351. 2006
  8. ncbi Recovery of free oligosaccharides from derivatives labeled by reductive amination
    Shigeo Suzuki
    Faculty of Pharmaceutical Sciences, Kinki University, Higashi Osaka, Osaka 577 8502, Japan
    Anal Biochem 354:94-103. 2006
  9. ncbi Granulocyte functions and changes in ability with age in newborns; Report no. 1: flow cytometric analysis of granulocyte functions in whole blood
    Naohiko Moriguchi
    Department of Pediatrics, Sakai Hospital, Kinki University School of Medicine, Osaka, Japan
    Pediatr Int 48:17-21. 2006
  10. ncbi Inhibition of Helicobacter pylori motility by (+)-Syringaresinol from unripe Japanese apricot
    Mitsuo Miyazawa
    Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University
    Biol Pharm Bull 29:172-3. 2006

Scientific Experts

Detail Information

Publications62

  1. ncbi Touch preparation of primary uterine pleomorphic rhabdomyosarcoma: report of a case with clinical cytopathologic features
    Yoh Watanabe
    Department of Obstetrics and Gynecology, Kinki University Faculty of Medicine, 377 2 Ohno Higashi, Osakasayama, Osaka 589 8511, Japan
    Acta Cytol 54:1027-30. 2010
    ..Primary pure uterine rhabdomyosarcoma (RMS) is an extremely rare tumor, and no cytopathologic characteristics of this tumor have been reported before...
  2. ncbi Biomechanical response of collagen fascicles to restressing after stress deprivation during culture
    Ei Yamamoto
    Biomechanics Laboratory, Department of Mechanical Engineering and Biomimetics, School of Biology Oriented Science and Technology, Kinki University, Kinokawa, Wakayama 649 6493, Japan
    J Biomech 40:2063-70. 2007
    ..These are similar to previous results observed in tendons and ligaments inside the body...
  3. ncbi Effects of some beta-adrenoceptor antagonists on orthostatic hypotension in repeatedly cold- (SART-) stressed rats
    Yoshinori Funakami
    Department of Pharmacology, Faculty of Pharmacy, Kinki University, Higashi Osaka, Japan
    Biol Pharm Bull 30:303-8. 2007
    ..The circulatory regulation in SART-stressed rats seems to be poorly functioning in nervous reflex in postural changes...
  4. ncbi Survey on cellular phone usage on students in Thailand
    Naohito Kawasaki
    School of Pharmacy, Kinki University, Kowake, Higashi Osaka, Osaka, Japan
    J Physiol Anthropol 25:377-82. 2006
    ..The Japanese students were surveyed in an earlier study by Toda et al.). Also, the CPDQ total score was high, which indicated a strong tendency toward dependence...
  5. ncbi A new ultrasonographic technique for diagnosing deep venous insufficiency--imaging and functional evaluation of venous valves by ultrasonography with improved resolution
    Atsushi Kotani
    Department of Clinical Laboratory, Kinki University Hospital, 377 2, Ohnohigashi, Osakasayama, Osaka, 589 8511 Japan
    Int J Cardiovasc Imaging 23:493-500. 2007
    ..In addition, we were able to demonstrate the time-course change of valve opening and closing, and quantitate the valve incompetence using M-mode ultrasonography...
  6. ncbi Suppression of MeIQ-induced SOS response by allylbenzenes from Asiasarum heterotropoides in the Salmonella typhimurium OY1001/1A2 umu test
    Mitsuo Miyazawa
    Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Higashiosaka shi, Osaka 577 8502, Japan
    Nat Prod Res 20:671-5. 2006
    ..4 mM, respectively. The ID50 values (50% inhibition dose) of these compounds were 0.125, 0.098 and 0.059 mM, respectively. On the other hand, compounds 1-3 showed weak suppressive effects of the SOS-inducing activity on activated MeIQ...
  7. ncbi Allergic contact dermatitis mimicking atopic dermatitis due to enoxolone in a topical medicament
    Naoki Oiso
    Department of Dermatology, Kinki University School of Medicine, 377 2 Ohno Higashi, Osaka Sayama, Osaka 589 8511, Japan
    Contact Dermatitis 54:351. 2006
  8. ncbi Recovery of free oligosaccharides from derivatives labeled by reductive amination
    Shigeo Suzuki
    Faculty of Pharmaceutical Sciences, Kinki University, Higashi Osaka, Osaka 577 8502, Japan
    Anal Biochem 354:94-103. 2006
    ....
  9. ncbi Granulocyte functions and changes in ability with age in newborns; Report no. 1: flow cytometric analysis of granulocyte functions in whole blood
    Naohiko Moriguchi
    Department of Pediatrics, Sakai Hospital, Kinki University School of Medicine, Osaka, Japan
    Pediatr Int 48:17-21. 2006
    ..The purpose of the present study was to estimate the characteristics of granulocyte function during the neonatal period...
  10. ncbi Inhibition of Helicobacter pylori motility by (+)-Syringaresinol from unripe Japanese apricot
    Mitsuo Miyazawa
    Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University
    Biol Pharm Bull 29:172-3. 2006
    ..Syringaresinol (1) inhibited >90% of the H. pylori motility at a concentration of 500 microg/ml and the IC50 value was 50 microg/ml...
  11. ncbi Development of residual strains in human vertebral trabecular bone after prolonged static and cyclic loading at low load levels
    Ei Yamamoto
    Orthopaedic Biomechanics Laboratory, Department of Mechanical Engineering, University of California, Berkeley, 94720 1740, USA
    J Biomech 39:1812-8. 2006
    ....
  12. ncbi [Three-dimensional atlas of subthalamic nucleus and its adjacent structures]
    Naoki Nakano
    Department of Neurosurgery, Kinki University School of Medicine, 377 2 Ohno Higashi, Osaka Sayama, Osaka 589 8511, Japan
    No Shinkei Geka 33:683-92. 2005
    ..Three-dimensional atlas also helped us make a decision for placement of the deep brain electrode and appropriate electrophysiological recording...
  13. ncbi Mizoribine in combination therapy with tacrolimus for living donor renal transplantation: analysis of a nationwide study in Japan
    T Akiyama
    Department of Urology, Sakai Hospital, Kinki University, Sakai City, Osaka, Japan
    Transplant Proc 37:843-5. 2005
  14. ncbi Applicability of the stages of change model for analyzing fruit and vegetable intake in relation to urinary potassium excretion: baseline results from the High-Risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study
    Junko Tamaki
    Department of Public Health, Kinki University School of Medicine, Osakasayama, Japan
    Hypertens Res 27:843-50. 2004
    ..08). This study supports the potential value of the Stages of Change model for increasing fruit and vegetable intake in the design of dietary intervention programs...
  15. ncbi Expression and DNA methylation patterns of Tslc1 and Dal-1 genes in hepatocellular carcinomas induced by N-nitrosodiethylamine in rats
    Toshifumi Tsujiuchi
    Laboratory of Cancer Biology and Bioinformatics, Department of Life Science, Faculty of Science and Engineering, Kinki University, Osaka 577 8502, Japan
    Cancer Sci 98:943-8. 2007
    ..Western blot analysis also revealed reduced expression of Tslc1 protein in the three HCC. These results suggest that alterations to the TSLC cascade might have a role in hepatocarcinogenesis using DEN in rats...
  16. ncbi Kinetic analysis of demetalation of bacteriochlorophyll c and e homologs purified from green sulfur photosynthetic bacteria
    Yoshitaka Saga
    Department of Chemistry, Faculty of Science and Engineering, Kinki University, Higashi Osaka, Osaka 577 8502, Japan
    FEBS Lett 581:1847-50. 2007
    ..Additional methyl groups at the 8(2)-position of both BChl c and e molecules had little effect on the demetalation kinetics...
  17. ncbi Effect of cholesterol, cholic acid and cholestyramine administration on the intestinal mRNA expressions related to cholesterol and bile acid metabolism in the rat
    Toshinori Kamisako
    Department of Hygiene, Kinki University School of Medicine, Osakasayama, Japan
    J Gastroenterol Hepatol 22:1832-7. 2007
    ....
  18. ncbi Efficacy of rituximab monotherapy for an elderly hemodialysis patient with primary cardiac lymphoma
    Yasuyoshi Morita
    Department of Hematology, Kinki University School of Medicine, Osaka Sayama
    Intern Med 49:2163-6. 2010
    ..The follow-up chest CT showed tumor disappearance with pericardial fluid after two courses of therapy. Rituximab monotherapy was effective for an elderly hemodialysis patient with PCL...
  19. doi Comparison of demetalation properties between zinc chlorin and zinc porphyrin derivatives: effect of macrocyclic structures
    Yoshitaka Saga
    Department of Chemistry, Faculty of Science and Engineering, Kinki University, Higashi Osaka, Osaka 577 8502, Japan
    Bioorg Med Chem 18:5697-700. 2010
    ..This indicates that the porphyrin macrocycle provides tolerance to removal of the central metal from cyclic tetrapyrrole ligands compared with the chlorin macrocycle...
  20. doi Enzymatic synthesis of caffeic acid phenethyl ester analogues in ionic liquid
    Atsushi Kurata
    Graduate School of Applied Biological Chemistry, Kinki University, 3327 204 Nakamachi, Nara City, Nara 631 8505, Japan
    J Biotechnol 148:133-8. 2010
    ..Additionally, we showed that both 2-cyclohexylethyl caffeate and 3-cyclohexylpropyl caffeate exhibit strong antiproliferative activities, which are comparable to that of 5-fluorouracil by MTT assay...
  21. ncbi [Search for TNF-alpha sensitivity degradation principles from medicinal foods-hepatoprotective amide constituents from Thai natural medicine Piper chaba]
    Toshio Morikawa
    Pharmaceutical Research and Technology Institute Kinki University
    Yakugaku Zasshi 130:785-91. 2010
    ..Moreover, a principal constituent, piperine, exhibited strong in vivo hepatoprotective effect at a dose of 5 mg/kg, p.o. and its mode of action was suggested to depend on the reduced sensitivity of hepatocytes to TNF-alpha...
  22. pmc The route of priming influences the ability of respiratory virus-specific memory CD8+ T cells to be activated by residual antigen
    Shiki Takamura
    Trudeau Institute, Saranac Lake, NY 12983, USA
    J Exp Med 207:1153-60. 2010
    ..Thus, two independent factors, initial CD8+ T cell priming in the MLN and prolonged presentation of residual antigen in the MLN, are required to maintain large numbers of antigen-specific memory CD8+ T cells in the lung airways...
  23. doi Premature terminal exhaustion of Friend virus-specific effector CD8+ T cells by rapid induction of multiple inhibitory receptors
    Shiki Takamura
    Department of Immunology, Kinki University School of Medicine, 377 2 Ohno Higashi, Osaka Sayama, Osaka 589 8511, Japan
    J Immunol 184:4696-707. 2010
    ..These results highlight FV's unique ability to evade virus-specific CD8(+) T cell responses and the importance of an early prophylactic approach for preventing terminal exhaustion of CD8(+) T cells...
  24. doi Long-term prognosis of acute pancreatitis in Japan
    Yoshifumi Takeyama
    Department of Surgery, Kinki University School of Medicine, Ohno Higashi, Osaka Sayama, Japan
    Clin Gastroenterol Hepatol 7:S15-7. 2009
    ..Mortality as a result of malignant disease was not excessive in the patients with history of acute pancreatitis...
  25. ncbi Emergency cesarean section as a result of acute eosinophilic pneumonia during pregnancy
    Yasushi Kotani
    Department of Obstetrics and Gynecology, Kinki University School of Medicine, Osaka, Japan
    Tohoku J Exp Med 219:251-5. 2009
    ..Both the mother and the baby were discharged on the 10(th) post-operative day and the patient has been leading a normal life with no recurrence for > 3 years since delivery...
  26. doi Neural stem cells and new neurons in the cerebral cortex of stroke-prone spontaneously hypertensive rats after stroke
    Tatsuki Itoh
    Department of Pathology, Kinki University School of Medicine, 377 2 Ohno Higashi, Osakasayama, Osaka, 589 8511, Japan
    J Mol Neurosci 41:55-65. 2010
    ..Immature cells and new neurons from the ipsilateral SVZ might migrate into the penumbra after cerebral stroke, and this is the first report of their observation after a spontaneous cerebral stroke...
  27. doi Expression of metallothionein mRNAs on mouse cerebellum microglia cells by thimerosal and its metabolites
    Takeshi Minami
    Department of Life Sciences, School of Science and Engineering, Kinki University, 3 4 1 Kowakae, Higashi Osaka, Osaka 577 8502, Japan
    Toxicology 261:25-32. 2009
    ..The reduction of MT-1 mRNA level by thiosalicylate may affect the proliferation of C8-B4 cells...
  28. ncbi Phase I study of combination chemotherapy with irinotecan hydrochloride and nedaplatin for cervical squamous cell carcinoma: Japanese gynecologic oncology group study
    Kaichiro Yamamoto
    Department of Obstetrics and Gynecology, Sakai Hospital, Kinki University School of Medicine, Osaka 590 0132, Japan
    Oncol Rep 21:1005-9. 2009
    ..The maximum tolerated dose was not reached, even at the highest dose level (level 4; NDP: 80 mg/m2). No further dose escalation was carried out, and level 4 (CPT-11: 60 mg/m2, NDP: 80 mg/m2) was determined as the RD...
  29. ncbi Observation of interactions of human serum components with transferrin by affinity capillary electrophoresis
    Atsushi Taga
    School of Pharmacy, Kinki University, 3 4 1 Kowakae, Higashi Osaka 577 8502, Japan
    J Pharm Biomed Anal 46:395-8. 2008
    ..TF is well known as a ferric ion transfer protein, and hence formation of this protein might be changed by ferric ion. The presence of iron(II) played no essential role in this interaction, though its influence was not negligible...
  30. ncbi Roles of human CYP2A6 and rat CYP2B1 in the oxidation of (+)-fenchol by liver microsomes
    M Miyazawa
    Faculty of Science and Engineering, Department of Applied Chemistry, Kinki University, Osaka, Japan
    Xenobiotica 37:943-53. 2007
    ....
  31. ncbi The carbonic anhydrase domain protein nacrein is expressed in the epithelial cells of the mantle and acts as a negative regulator in calcification in the mollusc Pinctada fucata
    Hiroshi Miyamoto
    Faculty of Biology Oriented Science and Technology, Department of Molecular Genetics, Kinki University, Uchita, Wakayama, Japan
    Zoolog Sci 22:311-5. 2005
    ..Together these studies suggest that nacrein functions as a negative regulator in calcification in the extrapallial space between the shell and the mantle by inhibiting the precipitation of CaCO3...
  32. ncbi Chlorogenate hydrolase-catalyzed synthesis of hydroxycinnamic acid ester derivatives by transesterification, substitution of bromine, and condensation reactions
    N Kishimoto
    Graduate School of Applied Life Chemistry, Kinki University, Nara City, Nara 631 8505, Japan
    Appl Microbiol Biotechnol 68:198-202. 2005
    ..The enzyme may bind to the caffeoyl moiety of 5-CQA or CA to form an enzyme-substrate complex. It then catalyzes four different reactions corresponding to the reaction conditions...
  33. ncbi Study of metallothionein using capillary zone electrophoresis
    Takeshi Minami
    Laboratory of Environmental Biology, Department of Life Science, School of Science and Engineering, Kinki University, 3 4 1 Kowakae, Higashiosaka, Osaka 577 8502, Japan
    J Chromatogr B Analyt Technol Biomed Life Sci 781:303-11. 2002
    ..CZE-ICP-isotope dilution (ID)-MS is also reported to be able to quantify MT isoforms. CZE combined with other techniques is very effective for separation and quantitative and qualitative analyses of MT isoforms in biological materials...
  34. ncbi Quantification of pilsicainide in serum by capillary electrophoresis
    Toshihiro Kitahashi
    Department of Laboratory Medicine, Kinki University School of Medicine, 377 2 Ohno Higashi, Osakasayama, Japan
    J Pharm Biomed Anal 29:625-9. 2002
    ..74-5.12% and the recovery rate was 61-63%. Disopyramide, another anti-arrhythmic drug, was close to pilsicainide in terms of migration time. This method was applied to determination of pilsicainide in serum samples...
  35. ncbi Biotransformation of (R)- and (S)-terpinen-4-ol by the larvae of common cutworm (Spodoptera litura)
    M Miyazawa
    Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Kowakae, Higashiosaka shi, Osaka 577 8502, Japan
    J Agric Food Chem 49:4312-4. 2001
    ..Similarly, (S)-terpinen-4-ol was transformed mainly to (S)-p-menth-1-en-4,7-diol. The C-7 position (allylic methyl group) of (R)- and (S)-terpinen-4-ol was preferentially oxidized...
  36. ncbi Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes
    M Miyazawa
    Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Kowakae, Higashiosaka, Osaka 577 8502, Japan
    Drug Metab Dispos 29:200-5. 2001
    ..These results suggest that 1,8-cineole, a monoterpenoid present in nature, is one of the effective substrates for CYP3A enzymes in rat and human liver microsomes...
  37. ncbi Dose and dose-rate effects of X rays and fission neutrons on lymphocyte apoptosis in p53(+/+) and p53(-/-) mice
    K Fujikawa
    Atomic Energy Research Institute, Kinki University, Higashiosaka, Japan
    J Radiat Res 41:113-27. 2000
    ..4 Gy/min) and chronic (3 mGy/min) gamma-irradiations. Namely, radiation-induced apoptosis in lymphocytes is a dose-rate independent event...
  38. ncbi Shedding of sulfated lipids into gastric fluid and inhibition of pancreatic DNase I by cholesterol sulfate in concert with bile acids
    M Iwamori
    Department of Biochemistry, Faculty of Science and Technology, Kinki University, Higashiosaka, Osaka, Japan
    Biochim Biophys Acta 1487:268-74. 2000
    ..18 of the optimum ratio for sodium taurocholate, and the molar ratio of CS to DNase I for complete inhibition was 342:1. Thus, CS was shown to play a role as an epithelial inhibitor of DNase I in concert with bile acids...
  39. ncbi Oculocardiac reflex induced by zygomatic fracture; a case report
    M Kosaka
    Department of Plastic and Reconstructive Surgery, Kinki University, School of Medicine, Japan
    J Craniomaxillofac Surg 28:106-9. 2000
    ..After repair of the fracture, his arrhythmia completely disappeared. The pacemaker was removed on the first postoperative day. The pathogenesis of this rare case will be discussed...
  40. ncbi Long-term results of fractionated strontium-90 radiation therapy for pterygia
    Y Nishimura
    Department of Radiology, Kinki University School of Medicine, Osaka Sayama, Japan
    Int J Radiat Oncol Biol Phys 46:137-41. 2000
    ..The long-term safety and effectiveness of fractionated strontium-90 radiation therapy (RT) for pterygium were reviewed retrospectively...
  41. ncbi Antimutagenic activity of polymethoxyflavonoids from Citrus aurantium
    M Miyazawa
    Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Kowakae, Higashiosaka shi, Osaka 577 8502, Japan
    J Agric Food Chem 47:5239-44. 1999
    ..These compounds showed of all mutagen-induced SOS response in the umu test. In addition, compounds 1-3 exhibited antimutagenic activity in the S. typhimurium TA100 Ames test...
  42. ncbi Antimutagenic activity of isoflavones from soybean seeds (Glycine max merrill)
    M Miyazawa
    Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Osaka, Japan
    J Agric Food Chem 47:1346-9. 1999
    ..In addition to the antimutagenic activities of daidzein and genistein against Trp-P-1, frylfuramide and activated Trp-P-1 were assayed by an Ames test using S. typhimurium TA100...
  43. ncbi Sequence analysis of Stx2-converting phage VT2-Sa shows a great divergence in early regulation and replication regions
    H Miyamoto
    Faculty of Biology Oriented Science and Technology, Department of Molecular Genetics, Kinki University, Uchita, Wakayama, Japan
    DNA Res 6:235-40. 1999
    ....
  44. ncbi Involvement of endothelium-derived factors in controlling the active tone of smooth muscle in aorta from hypertensive rats
    F Sekiguchi
    Faculty of Pharmaceutical Sciences, Kinki University, Higashi Osaka, Japan
    J Smooth Muscle Res 34:221-32. 1998
    ..The involvement of endothelium-derived hyperpolarizing factor (EDHF) in the depressing effect of endothelium is thought to be small...
  45. ncbi Inhibition of liver metastases from neuraminidase-treated colon 26 cells by an anti-Thomsen-Friedenreich-specific monoclonal antibody
    H Shigeoka
    First Department of Surgery, Kinki University School of Medicine, Osaka, Japan
    Tumour Biol 20:139-46. 1999
    ..This could be prevented by an antibody to TF (A78-G/A7), but not by a control antibody. The results may open up a new strategy for the prophylaxis of metastatic spread to the liver...
  46. ncbi Decolorization of indigo carmine by charcoal from extracted residue of coffee beans
    Takeo Nakamura
    School of Pharmaceutical Sciences, Kinki University, Kowakae, Higashi Osaka, Osaka, Japan
    J Environ Sci Health A Tox Hazard Subst Environ Eng 38:555-62. 2003
    ....
  47. ncbi A new fungal lectin recognizing alpha(1-6)-linked fucose in the N-glycan
    Yasuo Oda
    Faculty of Pharmaceutical Sciences, Kinki University, Kowakae 3 4 1, Higashi Osaka, Japan 577 8502
    J Biol Chem 278:32439-47. 2003
    ..Together, these results show that RSL recognizes the core structure of N-glycans with alpha(1-6)-linked l-fucose residues. This specificity could make RSL a valuable tool for glycobiological studies...
  48. ncbi [Pain information pathways from the periphery to the cerebral cortex]
    Ryotaro Kuroda
    Faculty of Pharmaceutical Sciences, Kinki University, 3 4 1 Kowakae, Higashi Osaka 577 8502, Japan
    Yakugaku Zasshi 123:533-46. 2003
    ..Based on the these findings, PAR-1 and PAR-2 are attracting interest as target molecules for new drug development...
  49. ncbi Establishment and characterization of a rat lung adenocarcinoma cell line with low malignant potential
    Toshifumi Tsujiuchi
    Laboratory of Cancer Biology and Bioinformatics, Department of Life Science, Faculty of Science and Technology, Kinki University, 3 4 1 Kowakae, Higashiosaka, Osaka 577 8502, Japan
    Cancer Lett 217:97-103. 2005
    ..It should be useful for further investigation of in vivo growth mechanisms, especially tumor progression, of lung adenocarcinomas, since it has low malignant potential...
  50. ncbi Polymorphism of the mast cell chymase gene (CMA1) promoter region: lack of association with asthma but association with serum total immunoglobulin E levels in adult atopic dermatitis
    T Iwanaga
    Division of Human Genetics, School of Medicine, University of Southampton, Southampton General Hospital, Southhampton, UK
    Clin Exp Allergy 34:1037-42. 2004
    ..We have examined association of a CMA1 variant in relation to asthma in a large UK Caucasian family cohort...
  51. ncbi Superoxide dismutase reduces the impairment of endothelium-dependent relaxation in the spontaneously hypertensive rat aorta
    Fumiko Sekiguchi
    School of Pharmaceutical Sciences, Kinki University, Higashi Osaka, Japan
    J Smooth Muscle Res 40:65-74. 2004
    ..The L-NOARG-induced inhibition of EDR in WKY may be produced, in part, by the reduction of effective NO due to its destruction by superoxide...
  52. ncbi The cytokine regulation of SPARC production by rabbit corneal epithelial cells and fibroblasts in vitro
    Kosuke Abe
    Department of Ophthalmology, Kinki University School of Medicine, Osaka Sayama City, Osaka, 589 8511, Japan
    Cornea 23:172-9. 2004
    ..To understand the metabolism of SPARC in the cornea, we investigated the effects of cytokines and growth factors on SPARC synthesis by rabbit corneal epithelial cells and fibroblasts...
  53. ncbi Herpes simplex virus genome quantification in two patients who developed herpetic epithelial keratitis during treatment with antiglaucoma medications
    Tatsunori Deai
    Department of Ophthalmology, Kinki University School of Medicine, Osaka Sayama City, Japan
    Cornea 23:125-8. 2004
    ..We quantitated herpes simplex virus (HSV) DNA in tear film obtained from 2 patients who developed herpetic epithelial keratitis (HEK) during treatment with latanoprost and a beta-blocker...
  54. ncbi Adjuvant oral 5-fluorouracil for cervical cancer: Japanese Gynecologic Oncology Group report
    Kaichiro Yamamoto
    Department of Obstetrics and Gynecology, Sakai Hospital, Kinki University School of Medicine, Osaka 590 0132, Japan
    Int J Oncol 24:1175-9. 2004
    ..Oral 5-FU after radical hysterectomy with radiotherapy appears useful for patients with low-stage cervical cancer who have some risk factors but not for those with pelvic lymph node metastases...
  55. ncbi Spontaneous closure of ventricular septal defects followed up from <3 months of age
    Toshiharu Miyake
    Division of Pediatric Cardiology, Department of Pediatrics, Kinki University School of Medicine, Osakasayama, Japan
    Pediatr Int 46:135-40. 2004
    ..This study evaluates the incidence and timing of spontaneous closure (SC) of ventricular septal defect (VSD) using Doppler color flow mapping...
  56. ncbi Tyrosinase inhibitor from black rice bran
    Mitsuo Miyazawa
    Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Kowakae, Higashiosaka shi, Osaka 577 8502, Japan
    J Agric Food Chem 51:6953-6. 2003
    ....
  57. ncbi Novel synthesis of 2'-O modified oligonucleotides by solid phase fragment condensation
    Kotomi Sasaki
    Department of Biological and Environmental Chemistry, Kyushu School of Engineering, Kinki University, Iizuka, Fukuoka, Japan
    Nucleosides Nucleotides Nucleic Acids 22:1447-9. 2003
  58. ncbi Stereospecific hydroxylation of (+)-cedrol by using human skin microbial flora Staphylococcus epidermidis
    Mitsuo Miyazawa
    Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, 3 4 1, Kowakae, Higashiosaka shi, Osaka 577 8502, Japan
    Nat Prod Res 17:313-7. 2003
    ..Microbial transformation of (+)-cedrol was investigated by using Staphylococcus epidermidis and found that stereospecific hydroxylation of (+)-cedrol occurred at the C-3 position to form (+)-(3S)-3-hydroxycedrol...
  59. ncbi Pyruvate and acetate metabolism in termite mitochondria
    Shuji Itakura
    Department of Agricultural Chemistry, Faculty of Agriculture, Kinki University, 3327 204, Naka machi, Nara 31 8505, Japan
    J Insect Physiol 49:917-26. 2003
    ..walkeri suggest that pyruvate is rapidly metabolised, whereas the low mitochondrial PDHc activity of C. formosanus suggests that in this species more pyruvate is produced than can be oxidised in the termite tissues...
  60. ncbi Concurrent chemoradiotherapy with protracted infusion of 5-FU and cisplatin for postoperative recurrent or residual esophageal cancer
    Yasumasa Nishimura
    Department of Radiology, Kinki University School of Medicine, Osaka Sayama, Osaka, Japan
    Jpn J Clin Oncol 33:341-5. 2003
    ..We carried out the present study to investigate the feasibility and effectiveness of concurrent chemoradiotherapy (CT-RT) for postoperative recurrent esophageal cancer, which are, at present, unclear...
  61. ncbi Eosinophilic colitis in a patient with acute myeloid leukemia after allogeneic bone marrow transplantation
    Takashi Ashida
    Division of Hematology, Nephrology and Rheumatology, Department of Internal Medicine, Kinki University School of Medicine, Osakasayama, Osaka, Japan
    Int J Hematol 78:76-8. 2003
    ..To our knowledge, eosinophilic colitis has rarely been reported in association with allogeneic bone marrow transplantation...
  62. ncbi State of imidazole side chain of hen lysozyme modified with histamine and Japanese quail lysozyme. A study by immobilized metal ion affinity chromatography
    T Fukamizo
    Laboratory of Biophysical Chemistry, Faculty of Agriculture, Kinki University, Nara, Japan
    Biosci Biotechnol Biochem 62:2239-41. 1998
    ....