Hiroki Shimizu

Summary

Affiliation: Kawasaki Medical School
Country: Japan

Publications

  1. doi request reprint Critical role of interleukin-5 in the development of a mite antigen-induced chronic bronchial asthma model
    Hiroki Shimizu
    Department of Respiratory Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701 0192, Japan
    Inflamm Res 62:911-7. 2013
  2. doi request reprint Stability of sealed-bag samples for off-line measurement of fractional exhaled nitric oxide
    Hiroki Shimizu
    Department of Respiratory Medicine, Kawasaki Medical School, Japan
    Ann Allergy Asthma Immunol 106:378-80. 2011
  3. doi request reprint Preventive effect of galectin-9 on double-stranded RNA-induced airway hyperresponsiveness in an exacerbation model of mite antigen-induced asthma in mice
    Shigeki Katoh
    1Department of Respiratory Medicine, Kawasaki Medical School, Okayama, Japan
    Exp Lung Res 39:453-62. 2013
  4. doi request reprint Step-down of budesonide/formoterol in early stages of asthma treatment leads to insufficient anti-inflammatory effect
    Yasushi Obase
    Department of Respiratory Medicine, Kawasaki Medical School, Matsushima, Kurashiki, Japan
    J Asthma 50:718-21. 2013
  5. pmc Comparison of T-cell interferon-gamma release assays for Mycobacterium tuberculosis-specific antigens in patients with active and latent tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Japan
    Lung 188:283-7. 2010
  6. ncbi request reprint [Usefulness of fractional exhaled nitric oxide measurement for cough treatment]
    Hiroki Shimizu
    Department of Respiratory Medicine, Kawasaki Medical School
    Nihon Kokyuki Gakkai Zasshi 49:156-60. 2011
  7. ncbi request reprint Clinical evaluation of the T-SPOT.TB test for patients with indeterminate results on the QuantiFERON TB-2G test
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Intern Med 48:137-42. 2009
  8. doi request reprint Clinical evaluation of QuantiFERON TB-2G test in patients with healed pulmonary tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    J Infect Chemother 15:288-92. 2009
  9. doi request reprint Increased Galectin-9 Concentration and Number of CD4+Foxp3high+Cells in Bronchoalveolar Lavage Fluid of Patients with Cryptogenic Organizing Pneumonia
    Shigeki Katoh
    Department of Respiratory Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701 0192, Japan
    Lung 193:683-9. 2015
  10. ncbi request reprint Increased levels of plasma galectin-9 in patients with influenza virus infection
    Shigeki Katoh
    Department of Respiratory Medicine, Kawasaki Medical School
    Tohoku J Exp Med 232:263-7. 2014

Detail Information

Publications20

  1. doi request reprint Critical role of interleukin-5 in the development of a mite antigen-induced chronic bronchial asthma model
    Hiroki Shimizu
    Department of Respiratory Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701 0192, Japan
    Inflamm Res 62:911-7. 2013
    ..Interleukin (IL)-5 plays an important role in the pathogenesis of asthma. The involvement of IL-5 receptor-mediated cellular signals in the pathogenesis of a mite antigen-induced chronic asthma model was investigated...
  2. doi request reprint Stability of sealed-bag samples for off-line measurement of fractional exhaled nitric oxide
    Hiroki Shimizu
    Department of Respiratory Medicine, Kawasaki Medical School, Japan
    Ann Allergy Asthma Immunol 106:378-80. 2011
    ..It can be measured with on- and off-line methods. In the latter, sample storage is possible; this is useful in Japan, because the number of facilities in which this instrument has been installed is limited...
  3. doi request reprint Preventive effect of galectin-9 on double-stranded RNA-induced airway hyperresponsiveness in an exacerbation model of mite antigen-induced asthma in mice
    Shigeki Katoh
    1Department of Respiratory Medicine, Kawasaki Medical School, Okayama, Japan
    Exp Lung Res 39:453-62. 2013
    ..We also examined the preventive effects of recombinant galectin-9 (Gal-9) on acute asthma exacerbation in this model...
  4. doi request reprint Step-down of budesonide/formoterol in early stages of asthma treatment leads to insufficient anti-inflammatory effect
    Yasushi Obase
    Department of Respiratory Medicine, Kawasaki Medical School, Matsushima, Kurashiki, Japan
    J Asthma 50:718-21. 2013
    ..In this study, we obtained fractional exhaled nitric oxide (FeNO) measurements to clarify whether the anti-inflammatory effect of budesonide/formoterol is shortened by step-down...
  5. pmc Comparison of T-cell interferon-gamma release assays for Mycobacterium tuberculosis-specific antigens in patients with active and latent tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Japan
    Lung 188:283-7. 2010
    ..However, there was an overlap in the IFN-gamma levels between active TB disease and LTBI groups. Therefore, it would be difficult to use the QFT-2G test to completely discriminate active TB disease from LTBI...
  6. ncbi request reprint [Usefulness of fractional exhaled nitric oxide measurement for cough treatment]
    Hiroki Shimizu
    Department of Respiratory Medicine, Kawasaki Medical School
    Nihon Kokyuki Gakkai Zasshi 49:156-60. 2011
    ..046). In patients with cough variant asthma or bronchial asthma, the numbers were 2.15 +/- 1.60 and 1.40 +/- 0.67 before and after FeNO measurement, respectively (p = 0.003). FeNO measurement may be useful for cough treatment...
  7. ncbi request reprint Clinical evaluation of the T-SPOT.TB test for patients with indeterminate results on the QuantiFERON TB-2G test
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Intern Med 48:137-42. 2009
    ..To evaluate the clinical utility of the T-SPOT.TB test for patients with indeterminate results on the QFT-2G test...
  8. doi request reprint Clinical evaluation of QuantiFERON TB-2G test in patients with healed pulmonary tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    J Infect Chemother 15:288-92. 2009
    ....
  9. doi request reprint Increased Galectin-9 Concentration and Number of CD4+Foxp3high+Cells in Bronchoalveolar Lavage Fluid of Patients with Cryptogenic Organizing Pneumonia
    Shigeki Katoh
    Department of Respiratory Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701 0192, Japan
    Lung 193:683-9. 2015
    ..We examined the role of Gal-9 in the pathogenesis of one of the major idiopathic interstitial pneumonias, cryptogenic organizing pneumonia (COP) as compared with idiopathic pulmonary fibrosis (IPF)...
  10. ncbi request reprint Increased levels of plasma galectin-9 in patients with influenza virus infection
    Shigeki Katoh
    Department of Respiratory Medicine, Kawasaki Medical School
    Tohoku J Exp Med 232:263-7. 2014
    ..These findings support our proposal that Gal-9 production is induced by influenza virus infection in humans. In conclusion, plasma Gal-9 could be a new biomarker for patients with influenza infection. ..
  11. doi request reprint Possible regulatory role of galectin-9 on Ascaris suum-induced eosinophilic lung inflammation in mice
    Shigeki Katoh
    Department of Respiratory Medicine, Kawasaki Medical School, Okayama, Japan
    Int Arch Allergy Immunol 158:58-65. 2012
    ..We evaluated the role of Gal-9 in Ascaris suum-induced eosinophilic lung inflammation in mice...
  12. pmc Nutritional deficits in elderly smokers with respiratory symptoms that do not fulfill the criteria for COPD
    Yasushi Obase
    Department of Respiratory Medicine, Kawasaki Medical School, Kawasaki University of Medical Welfare, Kurashiki, Okayama, Japan
    Int J Chron Obstruct Pulmon Dis 6:679-83. 2011
    ....
  13. ncbi request reprint Mycoplasma pneumoniae pneumonia in the elderly
    Naoyuki Miyashita
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Med Sci Monit 14:CR387-91. 2008
    ..Mycoplasma pneumoniae is one of the most common causes of community-acquired pneumonia (CAP). This infection occurs predominantly in school-aged children and younger adults, but may also occur in the elderly...
  14. doi request reprint CD44 is critical for airway accumulation of antigen-specific Th2, but not Th1, cells induced by antigen challenge in mice
    Shigeki Katoh
    Department of Respiratory Medicine, Kawasaki Medical School, Okayama, Japan
    Eur J Immunol 41:3198-207. 2011
    ..Our findings indicate that CD44 expressed on CD4(+) T cells plays a critical role in the accumulation of antigen-specific Th2 cells, but not Th1 cells, in the airway and in the development of AHR induced by antigen challenge...
  15. ncbi request reprint False negative results of QuantiFERON TB-2G test in patients with active tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Matsushima, Kurashiki, Japan
    Jpn J Infect Dis 62:300-2. 2009
    ....
  16. doi request reprint Rapid diagnosis of tuberculous pleuritis by a T-cell interferon-gamma release assay
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Scand J Infect Dis 41:232-6. 2009
    ..to analyze MTB-specific T-cells in pleural effusion mononuclear cells by ELISpot is feasible in routine clinical practice and may be useful for a rapid and accurate diagnosis of tuberculous pleuritis...
  17. doi request reprint An asymptomatic case of pulmonary cryptococcosis with endobronchial polypoid lesions and bilateral infiltrative shadow
    Hiroki Shimizu
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701 0192, Japan
    J Infect Chemother 14:315-8. 2008
    ..Histopathological examination of transbronchial biopsy specimens demonstrated cryptococcal organisms. After fluconazole therapy for 4 months, the infiltrate had decreased in size and the bronchial polypoid lesions had disappeared...
  18. doi request reprint High serum arginase I levels in asthma: its correlation with high-sensitivity C-reactive protein
    Keiki Ogino
    Department of Public Health, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
    J Asthma 48:1-7. 2011
    ..Much attention has been directed to the induction of arginase I in the lung of asthmatic mice. However, there is no agreement on the changes of serum arginase activity in asthmatic patients among previous studies...
  19. ncbi request reprint Clinical usefulness of fluoro-2-deoxy-D-glucose PET in a case with multiple bone metastases of carcinoid tumor after ten years
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Intern Med 48:1919-23. 2009
    ....
  20. ncbi request reprint Assessment of the usefulness of sputum Gram stain and culture for diagnosis of community-acquired pneumonia requiring hospitalization
    Naoyuki Miyashita
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Med Sci Monit 14:CR171-6. 2008
    ..The usefulness of sputum Gram stain and culture in guiding microbiological diagnosis of community-acquired pneumonia (CAP) is controversial. We evaluated the role of sputum examination at a university teaching hospital...