- Matrix metalloproteinase and alphavbeta3 integrin-dependent vascular smooth muscle cell invasion through a type I collagen latticeS Kanda
Department of Geriatrics, Nagoya University Graduate School of Medicine, Nagoya
Arterioscler Thromb Vasc Biol 20:998-1005. 2000..A proteolytic process is required for SMC invasion, and the degradation of matrix proteins alters the relationship between matrix protein molecules and SMC surface integrins...
- Induction of apoptotic cell death in vascular endothelial cells cultured in three-dimensional collagen latticeM Kuzuya
Department of Geriatrics, Nagoya University School of Medicine, 65 Tsuruma cho, Showa Ku, Nagoya, 466 8550, Japan
Exp Cell Res 248:498-508. 1999..MMP derived from BAECs seems to play a key role in the release of cryptic ligands for alphavbeta3 integrin from intact collagen...
- Rho-Rho kinase is involved in smooth muscle cell migration through myosin light chain phosphorylation-dependent and independent pathwaysS Ai
Department of Geriatrics, Nagoya Graduate School of Medicine, 65 Tsuruma-cho, Showa-ku, 466-8550, Nagoya, Japan
Atherosclerosis 155:321-7. 2001..Whereas PDGF-mediated SMC migration is independent of increased MLC phosphorylation and other target molecules downstream of Rho-Rho kinase seem to be involved...
- VEGF protects against oxidized LDL toxicity to endothelial cells by an intracellular glutathione-dependent mechanism through the KDR receptorM Kuzuya
Department of Geriatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan
Arterioscler Thromb Vasc Biol 21:765-70. 2001..An anti-KDR antibody completely blocked these beneficial activities of VEGF. These results suggest that VEGF prevents Ox-LDL-induced endothelial cell damage via an intracellular GSH-dependent mechanism through the KDR/Flk-1 receptor...
- Glycation cross-links inhibit matrix metalloproteinase-2 activation in vascular smooth muscle cells cultured on collagen latticeM Kuzuya
Department of Geriatrics, Nagoya University Graduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya, Japan
Diabetologia 44:433-6. 2001....
- Risk Factors for the Discontinuation of Home Medical Care among Low-functioning Older PatientsH Umegaki
Hiroyuki Umegaki, Nagoya University Graduate School of Medicine, Department of Community Healthcare and Geriatrics, 65 Tsuruma cho, Showa Ku, Nagoya, Aichi, 466 8550, Japan, Phone 81 52 744 2364 Fax 81 52 744 2371 Email address
J Nutr Health Aging 20:453-7. 2016..In the present study, therefore, we investigated the factors associated with discontinuation of home medical care as a potentially preventable care transition event in older patients...