Naohito Uchida

Summary

Affiliation: Kagawa Medical University
Country: Japan

Publications

  1. ncbi request reprint Conversion of endoscopic nasobiliary drainage to internal drainage by means of endoscopic scissor forceps
    N Uchida
    Third Dept of Internal Medicine, Kagawa Medical University, Kagawa, Japan
    Endoscopy 34:180. 2002
  2. ncbi request reprint How many cytological examinations should be performed for the diagnosis of malignant biliary stricture via an endoscopic nasobiliary drainage tube?
    Naohito Uchida
    Department of Gastroenterology and Neurology, Kagawa University School of Medicine, Kagawa, Japan
    J Gastroenterol Hepatol 23:1501-4. 2008
  3. ncbi request reprint A case of gallbladder carcinoma diagnosed preoperatively by the detection of human telomerase reverse transcriptase mRNA in endoscopically obtained gallbladder bile
    N Uchida
    Third Department of Internal Medicine, Kagawa Medical University, Kagawa, Japan
    Endoscopy 35:185-8. 2003
  4. ncbi request reprint Conversion from external nasobiliary drainage to internal drainage using endoscopically available scissor forceps
    Naohito Uchida
    Third Department of Internal Medicine, Kagawa Medical University, 1750 1, Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Hepatogastroenterology 50:1891-3. 2003
  5. ncbi request reprint Vitamins K2, K3 and K5 exert in vivo antitumor effects on hepatocellular carcinoma by regulating the expression of G1 phase-related cell cycle molecules
    Shigeki Kuriyama
    Third Department of Internal Medicine, Kagawa University School of Medicine, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 27:505-11. 2005
  6. ncbi request reprint Relationship between the proliferative capability of hepatocytes and the intrahepatic expression of hepatocyte growth factor and c-Met in the course of cirrhosis development in rats
    Hideyuki Inoue
    Third Department of Internal Medicine, Kagawa University School of Medicine, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Mol Med 17:857-64. 2006
  7. ncbi request reprint In vitro and in vivo antitumor effects of vitamin K5 on hepatocellular carcinoma
    Misuzu Hitomi
    Third Department of Internal Medicine, Kagawa University School of Medicine, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 26:1337-44. 2005
  8. ncbi request reprint Enhanced expression of adaptor molecule p46 Shc in nuclei of hepatocellular carcinoma cells: study of LEC rats
    Shuhei Yoshida
    Third Department of Internal Medicine, Kagawa University School of Medicine, 1750 1 Ikenobe, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 25:1089-96. 2004
  9. ncbi request reprint Proliferative capability of hepatocytes and expression of G1-related cell cycle molecules in the development of liver cirrhosis in rats
    Fumi Funakoshi
    Third Department of Internal Medicine, Kagawa University School of Medicine, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Mol Med 13:779-87. 2004
  10. ncbi request reprint Combination of assay of human telomerase reverse transcriptase mRNA and cytology using bile obtained by endoscopic transpapillary catheterization into the gallbladder for diagnosis of gallbladder carcinoma
    Naohito Uchida
    Third Department of Internal Medicine, Kagawa Medical University, Kagawa, Japan
    Am J Gastroenterol 98:2415-9. 2003

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Conversion of endoscopic nasobiliary drainage to internal drainage by means of endoscopic scissor forceps
    N Uchida
    Third Dept of Internal Medicine, Kagawa Medical University, Kagawa, Japan
    Endoscopy 34:180. 2002
  2. ncbi request reprint How many cytological examinations should be performed for the diagnosis of malignant biliary stricture via an endoscopic nasobiliary drainage tube?
    Naohito Uchida
    Department of Gastroenterology and Neurology, Kagawa University School of Medicine, Kagawa, Japan
    J Gastroenterol Hepatol 23:1501-4. 2008
    ..The aim of this study is to determine the optimal number of repeated cytological sampling of bile obtained via an endoscopic nasobiliary drainage (ENBD) tube for the diagnosis of malignant biliary stricture...
  3. ncbi request reprint A case of gallbladder carcinoma diagnosed preoperatively by the detection of human telomerase reverse transcriptase mRNA in endoscopically obtained gallbladder bile
    N Uchida
    Third Department of Internal Medicine, Kagawa Medical University, Kagawa, Japan
    Endoscopy 35:185-8. 2003
    ..The molecular biological analysis of gallbladder bile collected using the ETCG technique was shown to be effective for diagnosing the nature of the polypoid lesion in the gallbladder...
  4. ncbi request reprint Conversion from external nasobiliary drainage to internal drainage using endoscopically available scissor forceps
    Naohito Uchida
    Third Department of Internal Medicine, Kagawa Medical University, 1750 1, Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Hepatogastroenterology 50:1891-3. 2003
    ..Although further studies using a larger number of patients are needed, our procedure is thought to be beneficial to patients undergoing endoscopic nasobiliary drainage...
  5. ncbi request reprint Vitamins K2, K3 and K5 exert in vivo antitumor effects on hepatocellular carcinoma by regulating the expression of G1 phase-related cell cycle molecules
    Shigeki Kuriyama
    Third Department of Internal Medicine, Kagawa University School of Medicine, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 27:505-11. 2005
    ..These results also indicate that vitamins K2, K3 and K5 may be useful agents for the treatment of patients with HCC...
  6. ncbi request reprint Relationship between the proliferative capability of hepatocytes and the intrahepatic expression of hepatocyte growth factor and c-Met in the course of cirrhosis development in rats
    Hideyuki Inoue
    Third Department of Internal Medicine, Kagawa University School of Medicine, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Mol Med 17:857-64. 2006
    ....
  7. ncbi request reprint In vitro and in vivo antitumor effects of vitamin K5 on hepatocellular carcinoma
    Misuzu Hitomi
    Third Department of Internal Medicine, Kagawa University School of Medicine, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 26:1337-44. 2005
    ..The results demonstrated here indicate that vitamin K5 may be a useful agent for the treatment of patients with HCC...
  8. ncbi request reprint Enhanced expression of adaptor molecule p46 Shc in nuclei of hepatocellular carcinoma cells: study of LEC rats
    Shuhei Yoshida
    Third Department of Internal Medicine, Kagawa University School of Medicine, 1750 1 Ikenobe, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 25:1089-96. 2004
    ....
  9. ncbi request reprint Proliferative capability of hepatocytes and expression of G1-related cell cycle molecules in the development of liver cirrhosis in rats
    Fumi Funakoshi
    Third Department of Internal Medicine, Kagawa University School of Medicine, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Mol Med 13:779-87. 2004
    ....
  10. ncbi request reprint Combination of assay of human telomerase reverse transcriptase mRNA and cytology using bile obtained by endoscopic transpapillary catheterization into the gallbladder for diagnosis of gallbladder carcinoma
    Naohito Uchida
    Third Department of Internal Medicine, Kagawa Medical University, Kagawa, Japan
    Am J Gastroenterol 98:2415-9. 2003
    ..We evaluated the usefulness of a molecular biological approach to the diagnosis of gallbladder carcinoma, in which gallbladder bile obtained by the ETCG technique is used...
  11. ncbi request reprint Estimation of the stent placement above the intact sphincter of Oddi against malignant bile duct obstruction
    Naohito Uchida
    Third Department of Internal Medicine, Kagawa University School of Medicine, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa, 761 0793, Japan
    J Gastroenterol 40:291-6. 2005
    ..Stent blockage occurs as a result of bacterial adherence to the inner wall of the stent. We evaluated the stent placement above the intact sphincter of Oddi to retain the function of the sphincter of Oddi as a bacteriological barrier...
  12. ncbi request reprint Annexin A2 expression and phosphorylation are up-regulated in hepatocellular carcinoma
    Hamdy Saad Mohammad
    Department of Gastroenterology and Neurology, Kagawa Medical University School of Medicine, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 33:1157-63. 2008
    ..These data suggest that overexpression and tyrosine phosphorylation of ANXA2 play important roles in the malignant transformation process leading to HCC and are related to the histological grade of HCC...
  13. ncbi request reprint Repetitive and safe transgene expression in rat liver is achievable by adenoviral infusion into the common bile duct
    Shigeki Kuriyama
    Third Department of Internal Medicine, Kagawa University School of Medicine, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Mol Med 16:503-8. 2005
    ....
  14. ncbi request reprint Safe and efficient transgene expression in rat hepatocytes induced by adenoviral administration into the biliary tract
    Shigeki Kuriyama
    Third Department of Internal Medicine, Kagawa University School of Medicine, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Oncol Rep 13:825-30. 2005
    ....
  15. ncbi request reprint Expression of G1 phase-related cell cycle molecules in naturally developing hepatocellular carcinoma of Long-Evans Cinnamon rats
    Yuko Kita
    Third Department of Internal Medicine, Kagawa University School of Medicine, Kagawa 761 0793, Japan
    Int J Oncol 24:1205-11. 2004
    ..These results indicate that cyclin D1 may be involved in the regeneration of hepatocytes rather than hepatocarcinogenesis, while Cdk4 but not Cdk6 may play an important role in the development of HCC...
  16. ncbi request reprint Reduced expression of cell cycle regulator p18(INK4C) in human hepatocellular carcinoma
    Asahiro Morishita
    Third Department of Internal Medicine, Kagawa Medical University, Kagawa, Japan
    Hepatology 40:677-86. 2004
    ..In conclusion, the loss of p18INK4C expression may play a role in the differentiation and development of HCC through the up-regulation of Cdk4 activity...
  17. ncbi request reprint Use of protein array to investigate receptor tyrosine kinases activated in gastric cancer
    Jian Gong
    Department of Gastroenterology and Neurology, Kagawa Medical University School of Medicine, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 36:101-6. 2010
    ..These data suggest that ErbB2 is activated in gastric cancer, and the ErbB2-targeting drug trastuzumab may be related to the reduction of Ang 1, FGFalpha, FGFbeta, TGFalpha and IL-8...
  18. ncbi request reprint Utility of pancreatic duct brushing for diagnosis of pancreatic carcinoma
    Naohito Uchida
    Department of Gastroenterology and Neurology, Kagawa University School of Medicine, 1750 1 Ikenobe, Miki cho, Kita gun 761 0793, Japan
    J Gastroenterol 42:657-62. 2007
    ..The aim of this study was to evaluate the usefulness of pancreatic duct brushing for diagnosis of pancreatic carcinoma...
  19. ncbi request reprint Sequential assessment of the intrahepatic expression of epidermal growth factor and transforming growth factor-beta1 in hepatofibrogenesis of a rat cirrhosis model
    Shigeki Kuriyama
    Department of Gastroenterology and Neurology, Kagawa University School of Medicine, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Mol Med 19:317-24. 2007
    ....
  20. ncbi request reprint Pre-cutting using a noseless papillotome with independent lumens for contrast material and guidewire
    Naohito Uchida
    Third Department of Internal Medicine, Kagawa University School of Medicine, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    J Gastroenterol Hepatol 20:947-50. 2005
    ..The technical success of therapeutic endoscopic retrograde cholangiopancreatography (ERCP) depends on selective cannulation into the bile duct. We have developed a new type of precut papillotome for selective cannulation...
  21. ncbi request reprint Identification of p46 Shc expressed in the nuclei of hepatocytes with high proliferating activity: Study of regenerating rat liver
    Jin Yuji
    Third Department of Internal Medicine, Kagawa University School of Medicine, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Mol Med 13:721-8. 2004
    ..Therefore, it is suggested that p46 Shc expressed in hepatocellular nuclei may be a useful marker for detecting hepatocytes with high proliferative activity...
  22. ncbi request reprint Comparison study of the expressions of myristoylated alanine-rich C kinase substrate in hepatocellular carcinoma, liver cirrhosis, chronic hepatitis, and normal liver
    Tsutomu Masaki
    Third Department of Internal Medicine, Kagawa Medical University, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 26:661-71. 2005
    ....
  23. ncbi request reprint Enhanced expression of p46 Shc in the nucleus and p52 Shc in the cytoplasm of human gastric cancer
    Satoko Yukimasa
    Third Department of Internal Medicine, Kagawa University School of Medicine, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 26:905-11. 2005
    ..Furthermore, unlike p52 Shc, p46 Shc was shown to be expressed solely in the nucleus, suggesting that p46 Shc expressed in the nucleus may play an important role in gastric carcinogenesis...
  24. ncbi request reprint Usefulness of single and repetitive percutaneous transhepatic gallbladder aspiration for the treatment of acute cholecystitis
    Kunihiko Tsutsui
    Department of Gastroenterology and Neurology, Kagawa University School of Medicine, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    J Gastroenterol 42:583-8. 2007
    ..The aim of this study was to evaluate the safety and usefulness of single and repetitive percutaneous transhepatic gallbladder aspiration (PTGBA) for the treatment of acute cholecystitis...
  25. ncbi request reprint Percutaneous ethanol and lipiodol injection therapy for hepatocellular carcinoma
    Kazutaka Kurokohchi
    Third Department of Internal Medicine, Kagawa University School of Medicine, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 24:381-7. 2004
    ....
  26. ncbi request reprint Antitumor effects of vitamins K1, K2 and K3 on hepatocellular carcinoma in vitro and in vivo
    Misuzu Hitomi
    Third Department of Internal Medicine, Kagawa University School of Medicine, Kagawa 761 0793, Japan
    Int J Oncol 26:713-20. 2005
    ..The results indicate that vitamins K2 and K3 may be useful agents for the treatment of patients with HCC...
  27. ncbi request reprint Vitamins K2, K3 and K5 exert antitumor effects on established colorectal cancer in mice by inducing apoptotic death of tumor cells
    Mutsumi Ogawa
    Department of Gastroenterology and Neurology, Kagawa University School of Medicine, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 31:323-31. 2007
    ....
  28. ncbi request reprint Identification of c-Yes expression in the nuclei of hepatocellular carcinoma cells: involvement in the early stages of hepatocarcinogenesis
    Takako Nonomura
    Department of Gastroenterology and Neurology, Kagawa University School of Medicine, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 30:105-11. 2007
    ..In conclusion, nuclear c-Yes expression was found in cancer cells at the early stages of hepatocarcinogenesis, suggesting that nucleus-located c-Yes may be a useful marker to detect early-stage HCC...
  29. ncbi request reprint Concomitant colitis associated with primary sclerosing cholangitis
    Naohito Uchida
    Third Department of Internal Medicine, Kagawa Medical University, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    J Gastroenterol 38:482-7. 2003
    ..The main lesions were found in the right-sided colon, with nonspecific inflammatory changes. These results suggest that colonoscopic surveillance of patients with PSC should be performed even if they do not have any colitis symptoms...
  30. ncbi request reprint Further resolution of alpha-fetoprotein glycoforms by two-dimensional isoelectric focusing and lectin affinity electrophoresis
    Eriko Ichikawa
    Third Department of Internal Medicine, Kagawa University School of Medicine, Kagawa, Japan
    Electrophoresis 27:3480-7. 2006
    ..Monosialo-AFP (AFP+II) was recovered in all the glycoforms of AFP-P2, -P3, -P4, and -P5; thus, AFP-P4 is more specific to HCC than monosialylated AFP+II...
  31. ncbi request reprint Abnormal bile flow in patients with achalasia
    Hideki Kobara
    Third Department of Internal Medicine, Kagawa Medical University, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    J Gastroenterol 38:327-31. 2003
    ..We performed cholescintigraphy, using (99m)Tc-pyridoxyl-5-methyl-tryptophan, in patients with esophageal achalasia to assess any possible dysfunction of the sphincter of Oddi associated with achalasia...
  32. ncbi request reprint Adenovirus-mediated gene transfer into rat livers: comparative study of retrograde intrabiliary and antegrade intraportal administration
    Shigeki Kuriyama
    Third Department of Internal Medicine, Kagawa University School of Medicine, Kagawa 761 0793, Japan
    Oncol Rep 13:69-74. 2005
    ....
  33. ncbi request reprint Adenocarcinoma arising from aberrant pancreas in the stomach
    Michiko Matsuki
    Department of Internal Medicine, Takamatsuhigashi National Hospital, Kagawa, Japan
    J Gastroenterol 40:652-6. 2005
    ..It should be noted that one of the causes of gastric outlet obstruction may be aberrant pancreas or its malignant transformation...
  34. ncbi request reprint Cyclins and cyclin-dependent kinases: comparative study of hepatocellular carcinoma versus cirrhosis
    Tsutomu Masaki
    Third Department of Internal Medicine, Kagawa Medical University, Kagawa, Japan
    Hepatology 37:534-43. 2003
    ..Cyclin D1, Cdk4, and cyclin E activation may be closely related to the histopathologic grade and progression of HCC...
  35. doi request reprint Paraneoplastic necrotizing myelopathy in a patient with advanced esophageal cancer: An autopsied case report
    Yoshiteru Urai
    Department of Gastroenterology and Neurology, School of Medicine, Kagawa University, Japan
    J Neurol Sci 280:113-7. 2009
    ..Taken together, these results suggest that there is an underlying autoimmune mechanism in paraneoplastic necrotizing myelopathy...
  36. ncbi request reprint Enlargement of thermal ablation zone by the combination of ethanol injection and radiofrequency ablation in excised bovine liver
    Seishiro Watanabe
    Third Department of Internal Medicine, Kagawa University School of Medicine, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Oncol 24:279-84. 2004
    ..For a given amount of energy and current administered, ethanol injection caused a better ablation effect, in terms of the size and shape of the ablated zone, than RFA with Radionics and RITA equipment...
  37. ncbi request reprint Effect of an aldose reductase inhibitor on esophageal dysfunction in diabetic patients
    Fumihiko Kinekawa
    Third Department of Internal Medicine, Kagawa University School of Medicine, Kita gun, Kagawa, Japan
    Hepatogastroenterology 52:471-4. 2005
    ..The aim of the present study is to examine the effect of an ARI on the esophageal dysfunction in diabetic patients by monitoring pH and motility of the esophagus...
  38. ncbi request reprint Aldehyde dehydrogenase-2 genotypes and HLA haplotypes in Japanese patients with esophageal cancer
    Seishiro Watanabe
    Third Department of Internal Medicine, Kagawa Medical University, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Oncol Rep 9:1063-8. 2002
    ..Therefore, the examination of genotypes of ALDH2 loci and HLA haplotypes may allow the early detection of esophageal cancer in the Japanese population...