Tokuhisa Hirouchi

Summary

Affiliation: Institute for Environmental Sciences
Country: Japan

Publications

  1. doi request reprint Upregulation of c-myc gene accompanied by PU.1 deficiency in radiation-induced acute myeloid leukemia in mice
    Tokuhisa Hirouchi
    Department of Radiobiology, Institute for Environmental Sciences, Hacchazawa, Takahoko, Rokkasho, Aomori, Japan
    Exp Hematol 36:871-85. 2008
  2. ncbi request reprint Cell surface marker phenotypes and gene expression profiles of murine radiation-induced acute myeloid leukemia stem cells are similar to those of common myeloid progenitors
    Tokuhisa Hirouchi
    Department of Radiobiology, Institute for Environmental Sciences, Japan
    Radiat Res 176:311-22. 2011
  3. pmc Microarray-based global mapping of integration sites for the retrotransposon, intracisternal A-particle, in the mouse genome
    Takashi Takabatake
    Department of Radiobiology, Institute for Environmental Sciences, 2 121, Hacchazawa, Takahoko, Rokkasho, Aomori 039 3213, Japan
    Nucleic Acids Res 36:e59. 2008
  4. doi request reprint Analysis of changes in DNA copy number in radiation-induced thymic lymphomas of susceptible C57BL/6, resistant C3H and hybrid F1 Mice
    Takashi Takabatake
    Department of Radiobiology, Institute for Environmental Sciences, Hacchazawa 2 121, Takahoko, Rokkasho, Aomori 039 3213, Japan
    Radiat Res 169:426-36. 2008
  5. ncbi request reprint Array-CGH analyses of murine malignant lymphomas: genomic clues to understanding the effects of chronic exposure to low-dose-rate gamma rays on lymphomagenesis
    Takashi Takabatake
    Department of Radiobiology, Institute for Environmental Sciences, 2 121, Hacchazawa, Takahoko, Rokkasho, Aomori 039 3213, Japan
    Radiat Res 166:61-72. 2006
  6. ncbi request reprint Spontaneously occurring mutations in the cyclobutane pyrimidine dimer photolyase gene cause different sensitivities to ultraviolet-B in rice
    Jun Hidema
    Department of Environmental Life Sciences, Graduate School of Life Sciences, Tohoku University, Sendai 980 8577, Japan
    Plant J 43:57-67. 2005
  7. pmc qUVR-10, a major quantitative trait locus for ultraviolet-B resistance in rice, encodes cyclobutane pyrimidine dimer photolyase
    Tadamasa Ueda
    National Institute of Agrobiological Sciences, Kannondai 2 1 2, Tsukuba, Ibaraki 305 8602, Japan
    Genetics 171:1941-50. 2005

Collaborators

Detail Information

Publications7

  1. doi request reprint Upregulation of c-myc gene accompanied by PU.1 deficiency in radiation-induced acute myeloid leukemia in mice
    Tokuhisa Hirouchi
    Department of Radiobiology, Institute for Environmental Sciences, Hacchazawa, Takahoko, Rokkasho, Aomori, Japan
    Exp Hematol 36:871-85. 2008
    ..To identify novel cooperative genes with PU.1, relevant to radiation-induced leukemogenesis, we analyzed the copy number alterations of tumor-related gene loci by array CGH, and their expressions in primary and transplanted AMLs...
  2. ncbi request reprint Cell surface marker phenotypes and gene expression profiles of murine radiation-induced acute myeloid leukemia stem cells are similar to those of common myeloid progenitors
    Tokuhisa Hirouchi
    Department of Radiobiology, Institute for Environmental Sciences, Japan
    Radiat Res 176:311-22. 2011
    ..Our results suggest that murine radiation-induced AML stem cells arise from radiosensitive cells at a common myeloid progenitor stage...
  3. pmc Microarray-based global mapping of integration sites for the retrotransposon, intracisternal A-particle, in the mouse genome
    Takashi Takabatake
    Department of Radiobiology, Institute for Environmental Sciences, 2 121, Hacchazawa, Takahoko, Rokkasho, Aomori 039 3213, Japan
    Nucleic Acids Res 36:e59. 2008
    ..These results demonstrate the first successful genome-wide mapping of a retrotransposon type in a mammalian genome...
  4. doi request reprint Analysis of changes in DNA copy number in radiation-induced thymic lymphomas of susceptible C57BL/6, resistant C3H and hybrid F1 Mice
    Takashi Takabatake
    Department of Radiobiology, Institute for Environmental Sciences, Hacchazawa 2 121, Takahoko, Rokkasho, Aomori 039 3213, Japan
    Radiat Res 169:426-36. 2008
    ..These findings provide important clues to both the mechanisms for accumulation of aberrations during radiation-induced lymphomagenesis and the different susceptibilities of C57BL/6 and C3H mice...
  5. ncbi request reprint Array-CGH analyses of murine malignant lymphomas: genomic clues to understanding the effects of chronic exposure to low-dose-rate gamma rays on lymphomagenesis
    Takashi Takabatake
    Department of Radiobiology, Institute for Environmental Sciences, 2 121, Hacchazawa, Takahoko, Rokkasho, Aomori 039 3213, Japan
    Radiat Res 166:61-72. 2006
    ....
  6. ncbi request reprint Spontaneously occurring mutations in the cyclobutane pyrimidine dimer photolyase gene cause different sensitivities to ultraviolet-B in rice
    Jun Hidema
    Department of Environmental Life Sciences, Graduate School of Life Sciences, Tohoku University, Sendai 980 8577, Japan
    Plant J 43:57-67. 2005
    ....
  7. pmc qUVR-10, a major quantitative trait locus for ultraviolet-B resistance in rice, encodes cyclobutane pyrimidine dimer photolyase
    Tadamasa Ueda
    National Institute of Agrobiological Sciences, Kannondai 2 1 2, Tsukuba, Ibaraki 305 8602, Japan
    Genetics 171:1941-50. 2005
    ..Furthermore, we were able to develop a UV-hyperresistant plant by overexpression of the photolyase gene...