Fuminori Tokunaga

Summary

Affiliation: Gunma University
Country: Japan

Publications

  1. pmc Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation
    Fuminori Tokunaga
    Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Gunma, Japan
    EMBO J 31:3856-70. 2012
  2. ncbi Linear ubiquitination: a novel NF-κB regulatory mechanism for inflammatory and immune responses by the LUBAC ubiquitin ligase complex
    Fuminori Tokunaga
    Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan
    Endocr J 59:641-52. 2012
  3. doi Linear ubiquitination-mediated NF-κB regulation and its related disorders
    Fuminori Tokunaga
    Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Gunma 371 8912, Japan
    J Biochem 154:313-23. 2013
  4. doi LUBAC, a novel ubiquitin ligase for linear ubiquitination, is crucial for inflammation and immune responses
    Fuminori Tokunaga
    Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Gunma 371 8512, Japan
    Microbes Infect 14:563-72. 2012
  5. pmc Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis
    Seshiru Nakazawa
    Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, 3 39 15 Showa Machi, Maebashi, Gunma 371 8512, Japan
    Nat Commun 7:12547. 2016
  6. doi An autosomal recessive mutation of DSG4 causes monilethrix through the ER stress response
    Madoka Kato
    Department of Dermatology, Gunma University Graduate School of Medicine, Gunma, Japan
    J Invest Dermatol 135:1253-60. 2015

Collaborators

  • Kazuhiro Iwai
  • Izuho Hatada
  • Osamu Nureki
  • Seshiru Nakazawa
  • Kiyoko Kamei
  • Madoka Kato
  • Hirotaka Takahashi
  • Ryohei Ishii
  • Hideshi Kawakami
  • Hidefumi Ito
  • Takashi Ayaki
  • Tatsuya Sawasaki
  • Daisuke Oikawa
  • Hiroyuki Takeda
  • Ryuichiro Ishitani
  • Izumi Takeyoshi
  • Akira Shimizu
  • Akemi Ishida-Yamamoto
  • Yutaka Shimomura
  • Osamu Ishikawa
  • Yoko Yokoyama
  • Kyoichi Kaira

Detail Information

Publications6

  1. pmc Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation
    Fuminori Tokunaga
    Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Gunma, Japan
    EMBO J 31:3856-70. 2012
    ..These findings provide new insight into the regulation of immune and inflammatory responses...
  2. ncbi Linear ubiquitination: a novel NF-κB regulatory mechanism for inflammatory and immune responses by the LUBAC ubiquitin ligase complex
    Fuminori Tokunaga
    Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan
    Endocr J 59:641-52. 2012
    ..This review summarizes these new findings on LUBAC- and linear ubiquitination-mediated NF-κB regulation and their implications in disorders...
  3. doi Linear ubiquitination-mediated NF-κB regulation and its related disorders
    Fuminori Tokunaga
    Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Gunma 371 8912, Japan
    J Biochem 154:313-23. 2013
    ..This review summarizes the molecular basis and the pathophysiological implications of the linear ubiquitination-mediated NF-κB activation pathway regulation by LUBAC. ..
  4. doi LUBAC, a novel ubiquitin ligase for linear ubiquitination, is crucial for inflammation and immune responses
    Fuminori Tokunaga
    Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Gunma 371 8512, Japan
    Microbes Infect 14:563-72. 2012
    ..Recent findings on the regulation of NF-κB by LUBAC and the diseases associated with this process are the focus of this review...
  5. pmc Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis
    Seshiru Nakazawa
    Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, 3 39 15 Showa Machi, Maebashi, Gunma 371 8512, Japan
    Nat Commun 7:12547. 2016
    ..Taken together, OPTN regulates both NF-κB activation and apoptosis via linear ubiquitin binding, and the loss of this ability may lead to ALS...
  6. doi An autosomal recessive mutation of DSG4 causes monilethrix through the ER stress response
    Madoka Kato
    Department of Dermatology, Gunma University Graduate School of Medicine, Gunma, Japan
    J Invest Dermatol 135:1253-60. 2015
    ....