Masao Omura

Summary

Affiliation: Graduate School
Country: Japan

Publications

  1. ncbi request reprint [Screening tests and diagnostic examinations of hypertensives for primary aldosteronism]
    Masao Omura
    Department of Internal Medicine, Social Insurance Central General Hospital, Shinjyuku ku, Tokyo
    Rinsho Byori 54:1157-63. 2006
  2. ncbi request reprint Prospective study on the prevalence of secondary hypertension among hypertensive patients visiting a general outpatient clinic in Japan
    Masao Omura
    Department of Medicine, Yokohama Rosai Hospital, Yokohama, Japan
    Hypertens Res 27:193-202. 2004
  3. ncbi request reprint Characterization of steroidogenic enzyme expression in aldosterone-producing adenoma: a comparison with various human adrenal tumors
    Ikki Sakuma
    Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama 222 0036, Japan
    Endocr J 60:329-36. 2013
  4. doi request reprint Vascular aldosterone production at the pre-diabetic stage of young Otsuka Long-Evans Tokushima Fatty (OLETF) rats, compared with Long-Evans Tokushima Otsuka (LETO) rats
    Yoko Matsuzawa
    Endocrinology and Diabetes Center, Yokohama Rosai Hospital, 3211 Kozukue cho, Kohoku Ku, Yokohama 222 0036, Japan
    Molecules 18:15636-47. 2013
  5. doi request reprint Clinical and Steroidogenic Characteristics of Aldosterone-Producing Adenomas With ATPase or CACNA1D Gene Mutations
    Takumi Kitamoto
    Endocrinology and Diabetes Center T K, S S, Y M, J S, M O, T N, Yokohama Rosai Hospital, Yokohama 222 0036, Japan and Department of Pathology Y Y, Y N, H S, Tohoku University School of Medicine, Sendai 980 8575, Japan
    J Clin Endocrinol Metab 101:494-503. 2016
  6. pmc Effect of atorvastatin on aldosterone production induced by glucose, LDL or angiotensin II in human renal mesangial cells
    Tetsuo Nishikawa
    Department of Medicine, Yokohama Rosai Hospital, Yokohama City, Kanagawa, Japan
    Arzneimittelforschung 60:445-51. 2010
  7. ncbi request reprint Prevalence of primary aldosteronism: should we screen for primary aldosteronism before treating hypertensive patients with medication?
    Tetsuo Nishikawa
    Division of Endocrinology and Metabolism, Department of Medicine, Yokohama Rosai Hospital, Yokohama City, Kanagawa 222 0036, Japan
    Endocr J 54:487-95. 2007
  8. doi request reprint The possibility of resistant hypertension during the treatment of hypertensive patients
    Tetsuo Nishikawa
    Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama, Japan
    Hypertens Res 36:924-9. 2013
  9. ncbi request reprint Pulmonary arterial sampling was useful for localizing ectopic ACTH production in a patient with bronchial carcinoid causing Cushing syndrome
    Ikki Sakuma
    Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama, Japan
    Hormones (Athens) 12:449-53. 2013
  10. ncbi request reprint [Prevalence and evaluation of secondary hypertension]
    Jun Saito
    Division of Endocrinology and Metabolism, Department of Medicine, Yokohama Rosai Hospital
    Nippon Rinsho . 2007

Collaborators

  • Tetsuo Nishikawa
  • Yasuhiro Nakamura
  • Fumitoshi Satoh
  • Sadayoshi Ito
  • Yutaka Oki
  • Hiroshi Itoh
  • Akiyo Tanabe
  • Kuniaki Mukai
  • Jun Saito
  • Yoko Matsuzawa
  • Sachiko Suematsu
  • Ikki Sakuma
  • Hironobu Sasano
  • Yuya Koike
  • Yuya Tsurutani
  • Seishi Matsui
  • Kohzoh Makita
  • Nobukazu Moriya
  • Takumi Kitamoto
  • Yuto Yamazaki
  • Ai Tamura
  • Yuichi Takashi
  • Shoichiro Nagasaka
  • Akiko Ishida
  • Chiho Sugisawa
  • Kosuke Inoue
  • Alfonso W D Obara
  • Koshiro Nishimoto
  • Maki Nagata
  • Minae Koga
  • Atsushi Inoue
  • Tsugio Seki
  • Takeo Kosaka
  • Yasuaki Kabe
  • Celso E Gomez-Sanchez
  • Mototsugu Oya
  • Seiji Matsui
  • Takashi Maekawa
  • Takamitsu Maehara
  • Naoki Hasegawa
  • Hiroko Ito
  • Tomoshige Kino
  • Koichiro Yoshimura
  • Yuki Yajima
  • Yuzuru Ito

Detail Information

Publications34

  1. ncbi request reprint [Screening tests and diagnostic examinations of hypertensives for primary aldosteronism]
    Masao Omura
    Department of Internal Medicine, Social Insurance Central General Hospital, Shinjyuku ku, Tokyo
    Rinsho Byori 54:1157-63. 2006
    ..85. Patients with unilateral secretion of aldosterone2 1400 ng/dl should undergo unilateral adrenalectomy and patients with bilateral secretion of aldosterone2 1400 ng/dl should be treated with antihypertensive agents...
  2. ncbi request reprint Prospective study on the prevalence of secondary hypertension among hypertensive patients visiting a general outpatient clinic in Japan
    Masao Omura
    Department of Medicine, Yokohama Rosai Hospital, Yokohama, Japan
    Hypertens Res 27:193-202. 2004
    ..Hypertensive patients should be screened for SH and the underlying disease treated appropriately to avoid long-term use of antihypertensive drugs and risks of atherosclerotic complications...
  3. ncbi request reprint Characterization of steroidogenic enzyme expression in aldosterone-producing adenoma: a comparison with various human adrenal tumors
    Ikki Sakuma
    Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama 222 0036, Japan
    Endocr J 60:329-36. 2013
    ..The CYP17/HSD3B2 ratio for mRNA in APA was significantly lower than those in the other groups. Low ratio of CYP17/HSD3B2 with high expression of CYP11B2 seems to explain steroidogenic characteristics of APA...
  4. doi request reprint Vascular aldosterone production at the pre-diabetic stage of young Otsuka Long-Evans Tokushima Fatty (OLETF) rats, compared with Long-Evans Tokushima Otsuka (LETO) rats
    Yoko Matsuzawa
    Endocrinology and Diabetes Center, Yokohama Rosai Hospital, 3211 Kozukue cho, Kohoku Ku, Yokohama 222 0036, Japan
    Molecules 18:15636-47. 2013
    ....
  5. doi request reprint Clinical and Steroidogenic Characteristics of Aldosterone-Producing Adenomas With ATPase or CACNA1D Gene Mutations
    Takumi Kitamoto
    Endocrinology and Diabetes Center T K, S S, Y M, J S, M O, T N, Yokohama Rosai Hospital, Yokohama 222 0036, Japan and Department of Pathology Y Y, Y N, H S, Tohoku University School of Medicine, Sendai 980 8575, Japan
    J Clin Endocrinol Metab 101:494-503. 2016
    ..This comparative study clarified the clinical characteristics and in vitro steroidogenic activities of aldosterone-producing adenomas (APAs) harboring ATPase or CACNA1D gene mutations...
  6. pmc Effect of atorvastatin on aldosterone production induced by glucose, LDL or angiotensin II in human renal mesangial cells
    Tetsuo Nishikawa
    Department of Medicine, Yokohama Rosai Hospital, Yokohama City, Kanagawa, Japan
    Arzneimittelforschung 60:445-51. 2010
    ....
  7. ncbi request reprint Prevalence of primary aldosteronism: should we screen for primary aldosteronism before treating hypertensive patients with medication?
    Tetsuo Nishikawa
    Division of Endocrinology and Metabolism, Department of Medicine, Yokohama Rosai Hospital, Yokohama City, Kanagawa 222 0036, Japan
    Endocr J 54:487-95. 2007
    ..Finally, we describe highlight key evidence for optimal methods for screening and definitely diagnosing PA among hypertensive patients in order to avoid misjudgment before or after treating hypertensive patients...
  8. doi request reprint The possibility of resistant hypertension during the treatment of hypertensive patients
    Tetsuo Nishikawa
    Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama, Japan
    Hypertens Res 36:924-9. 2013
    ....
  9. ncbi request reprint Pulmonary arterial sampling was useful for localizing ectopic ACTH production in a patient with bronchial carcinoid causing Cushing syndrome
    Ikki Sakuma
    Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama, Japan
    Hormones (Athens) 12:449-53. 2013
    ..We report a 44-year old man with ectopic adrenocorticotropic hormone (ACTH) syndrome caused by bronchial carcinoid that developed Cushing syndrome...
  10. ncbi request reprint [Prevalence and evaluation of secondary hypertension]
    Jun Saito
    Division of Endocrinology and Metabolism, Department of Medicine, Yokohama Rosai Hospital
    Nippon Rinsho . 2007
  11. doi request reprint Adrenal hormones before and after venography during adrenal venous sampling: a self-controlled study
    Yuya Koike
    Department of Interventional Radiology, Yokohama Rosai Hospital, 3211, Kozukue cho, Kouhoku ku, Yokohama, Kanagawa, 222 0036, Japan
    Jpn J Radiol . 2017
    ..The purpose of the present study was to investigate the effect of single shot venography on adrenal hormone production during AVS...
  12. doi request reprint Guanosine triphosphate can directly regulate cortisol production by activating Ca(2+)-messenger systems in bovine adrenal fasciculata cells
    Tetsuo Nishikawa
    Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama, Japan
    Endocr J 63:77-85. 2016
    ..In conclusion, it can be postulated that GTP-induced steroid secretion in bovine adrenal fasciculata cells is under paracrine or autocrine control. ..
  13. ncbi request reprint [Comparative studies on prevalence of primary aldosteronism and on diagnostic procedures]
    Tetsuo Nishikawa
    Division of Endocrinology and Metabolism, Department of Medicine, Yokohama Rosai Hospital
    Nihon Rinsho 63:342-7. 2005
  14. ncbi request reprint Calibration and evaluation of routine methods by serum certified reference material for aldosterone measurement in blood
    Tetsuo Nishikawa
    Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama, Japan
    Endocr J . 2016
    ..In conclusion, we succeeded to prepare the certified reference material of aldosterone for RM. Then, we can accurately calculate corrected values by using our equation for four RMs of determination of aldosterone...
  15. doi request reprint Undercarboxylated osteocalcin can predict insulin secretion ability in type 2 diabetes
    Yuichi Takashi
    Endocrinology and Diabetes Center, Yokohama Rosai Hospital, 3211 Kozukue cho, Kohoku Ku, Yokohama City, Kanagawa, 222 0036, Japan
    J Diabetes Investig . 2016
    ..025, p=0.047). ucOC reflects the reserve capacity of β-cell function, such as the bolus insulin secretion ability in patients with type 2 diabetes. This article is protected by copyright. All rights reserved...
  16. ncbi request reprint Guidelines for the diagnosis and treatment of primary aldosteronism--the Japan Endocrine Society 2009
    Tetsuo Nishikawa
    Department of Medicine, Yokohama Rosai Hospital, 3211 Kozukue cho, Kohokuku, Yokohama City, Japan
    Endocr J 58:711-21. 2011
    ..In contrast, patients with bilateral adrenal hyperplasia, or those unsuitable for surgery, are optimally treated medically with mineralocorticoid receptor antagonists...
  17. ncbi request reprint Unique cases of unilateral hyperaldosteronemia due to multiple adrenocortical micronodules, which can only be detected by selective adrenal venous sampling
    Masao Omura
    Department of Medicine, Yokohama Rosai Hospital, Yokohama, Kanagawa, Japan
    Metabolism 51:350-5. 2002
    ..Thus, primary aldosteronism due to UMN should be carefully examined for differential diagnosis of each form of hyperaldosteronemia...
  18. ncbi request reprint Mini review: surgical indications for adrenal incidentaloma
    Tetsuo Nishikawa
    Division of Endocrinology and Metabolism, Department of Medicine, Yokohama Rosai Hospital, 3211 Kozukue cho, Kohoku Ku, Yokohama City 222 0036, Japan
    Biomed Pharmacother 56:145s-148s. 2002
    ..Patients with adrenal incidentaloma should be carefully followed, especially regarding size and hormonal conditions...
  19. ncbi request reprint [Medical treatment for Cushing's syndrome]
    Tetsuo Nishikawa
    Department of Medicine, Yokohama Rosai Hospital
    Nihon Rinsho 66:186-91. 2008
    ..We rarely use trilostane which is an inhibitor against 3beta-hydroxysteroid dehydrogenase (3beta-HSD). Replacement therapy with hydrocortisone should be considered if adrenal failure will occur during treatment with those drugs...
  20. doi request reprint Somatic KCNJ5 mutation occurring early in adrenal development may cause a novel form of juvenile primary aldosteronism
    Ai Tamura
    Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama, 222 0036, Japan
    Mol Cell Endocrinol . 2016
    ....
  21. doi request reprint Aldosterone excess may inhibit insulin secretion: A comparative study on glucose metabolism pre- and post-adrenalectomy in patients with primary aldosteronism
    Yuya Tsurutani
    Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama 222 0036, Japan
    Endocr J . 2017
    ..However, because of a parallel increase in insulin resistance, plasma glucose levels remained unchanged...
  22. pmc The alkalizer citrate reduces serum uric Acid levels and improves renal function in hyperuricemic patients treated with the xanthine oxidase inhibitor allopurinol
    Jun Saito
    Division of Endocrinology and Metabolism, Department of Medicine, Yokohama Rosai Hospital, Yokohama, Japan
    Endocr Res 35:145-54. 2010
    ..0 mg/dL, or those diagnosed as having hyperuricemia in the past...
  23. ncbi request reprint Role of calcium messenger systems in ACTH-induced cortisol production in bovine adrenal fasciculo-reticularis cells
    Masao Omura
    Department of Medicine, Yokohama Rosai Hospital, Yokohama City, Kanagawa 222 0036, Japan
    Endocr J 54:585-92. 2007
    ..A phospholipase A2-dependent process may partly play a crucial role in the regulation of cortisol biosynthesis, when stimulated by low and high concentrations of ACTH...
  24. ncbi request reprint Is primary aldosteronism rare or common among hypertensive patients?
    Tetsuo Nishikawa
    Hypertens Res 30:103-4. 2007
  25. ncbi request reprint [Hypertension secondary to primary aldosteronism]
    Masao Omura
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Social Insurance Central General Hospital
    Nihon Rinsho 62:521-5. 2004
  26. doi request reprint Adrenal venous sampling is absolutely requisite for definitively diagnosing primary aldosteronism as well as for detecting laterality of the adrenal lesion
    Tetsuo Nishikawa
    Hypertens Res 30:1009-10. 2007
  27. ncbi request reprint [Occurrence and diagnosis of primary aldosteronism and its therapy]
    Tetsuo Nishikawa
    Nihon Naika Gakkai Zasshi 92:208-12. 2003
  28. ncbi request reprint Is it rare to have two adrenal diseases combined?
    Masao Omura
    Intern Med 41:911. 2002
  29. ncbi request reprint [Diagnostic efficacy of adrenal vein sampling]
    Masao Omura
    Nihon Naika Gakkai Zasshi 95:695-701. 2006
  30. ncbi request reprint [Primary pigmented nodular adrenocortical disease (PPNAD)]
    Masao Omura
    Division of Endocrinology and Metabolism, Department of Medicine, Social Insurance Central General Hospital
    Nihon Rinsho . 2006
  31. ncbi request reprint [Glucocorticoid remediable aldosteronism]
    Masao Omura
    Division of Endocrinology and Metabolism, Department of Medicine, Social Insurance Central General Hospital
    Nihon Rinsho . 2006
  32. ncbi request reprint [Primary aldosteronism due to unilateral adrenal hyperplasia]
    Masao Omura
    Division of Endocrinology and Metabolism, Department of Medicine, Social Insurance Central General Hospital
    Nihon Rinsho . 2006
  33. ncbi request reprint Clinical characteristics of aldosterone-producing microadenoma, macroadenoma, and idiopathic hyperaldosteronism in 93 patients with primary aldosteronism
    Masao Omura
    Department of Internal Medicine, Social Insurance Central General Hospital, Tokyo, Japan
    Hypertens Res 29:883-9. 2006
    ....
  34. ncbi request reprint [Diagnostic criteria for primary aldosteronism]
    Tetsuo Nishikawa
    Nihon Naika Gakkai Zasshi 96:2539-45. 2007