Minoru Fukuda

Summary

Country: Japan

Publications

  1. pmc Phase II study of irinotecan combined with carboplatin in previously untreated small-cell lung cancer
    A Kinoshita
    National Nagasaki Medical Center, Nagasaki, Japan
    Br J Cancer 94:1267-71. 2006
  2. pmc Efficacy and safety of amrubicin hydrochloride for treatment of relapsed small cell lung cancer
    Daiki Ogawara
    Department of Medicine, Sasebo Central Hospital
    Cancer Manag Res 2:191-5. 2010
  3. doi request reprint Phase II study of irinotecan and cisplatin with concurrent split-course radiotherapy in limited-disease small cell lung cancer
    Minoru Fukuda
    Department of Chemotherapy, Japanese Red Cross Nagasaki Genbaku Hospital, 3 15 Mori machi, Nagasaki, Japan
    Cancer Chemother Pharmacol 70:645-51. 2012
  4. ncbi request reprint Phase II study of irinotecan combined with carboplatin in previously untreated non-small-cell lung cancer
    Minoru Fukuda
    Division of Respiratory Disease, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701 0192, Okayama, Japan
    Cancer Chemother Pharmacol 54:573-7. 2004
  5. ncbi request reprint A phase I trial of carboplatin and etoposide for elderly (>or=75 year-old) patients with small-cell lung cancer
    Minoru Fukuda
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, and National Ureshino Hospital, Saga, Japan
    Cancer Chemother Pharmacol 58:601-6. 2006
  6. ncbi request reprint Irinotecan and cisplatin with concurrent split-course radiotherapy in locally advanced nonsmall-cell lung cancer: a multiinstitutional phase 2 study
    Minoru Fukuda
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Cancer 110:606-13. 2007
  7. ncbi request reprint Paclitaxel and cisplatin with concurrent radiotherapy followed by surgery in locally advanced thymic carcinoma
    Minoru Fukuda
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Okayama, Japan
    Anticancer Res 27:1601-4. 2007
  8. doi request reprint A phase I study of amrubicin and carboplatin for previously untreated patients with extensive-disease small cell lung cancer
    Minoru Fukuda
    Department of Medicine, Nagasaki Municipal Hospital, Nagasaki, Japan
    J Thorac Oncol 4:741-5. 2009
  9. ncbi request reprint Both bronchial and vascular stenting followed by chemoradiotherapy for locally advanced non-small cell lung cancer
    Minoru Fukuda
    Division of Respiratory Diseases, Department of Medicine and Kawasaki Medical School, Okayama, Japan
    Anticancer Res 26:565-7. 2006
  10. ncbi request reprint High-risk populations for nasal carriage of methicillin-resistant Staphylococcus aureus
    Minoru Fukuda
    Hirado Municipal Hospital, Hirado, Japan
    J Infect Chemother 10:189-91. 2004

Collaborators

Detail Information

Publications63

  1. pmc Phase II study of irinotecan combined with carboplatin in previously untreated small-cell lung cancer
    A Kinoshita
    National Nagasaki Medical Center, Nagasaki, Japan
    Br J Cancer 94:1267-71. 2006
    ..In conclusion, the combination of irinotecan and carboplatin is an active and well-tolerated regimen in cases of SCLC...
  2. pmc Efficacy and safety of amrubicin hydrochloride for treatment of relapsed small cell lung cancer
    Daiki Ogawara
    Department of Medicine, Sasebo Central Hospital
    Cancer Manag Res 2:191-5. 2010
    ..Therefore, it is necessary to conduct more clinical studies in non-Japanese patients to confirm the efficacy of amrubicin...
  3. doi request reprint Phase II study of irinotecan and cisplatin with concurrent split-course radiotherapy in limited-disease small cell lung cancer
    Minoru Fukuda
    Department of Chemotherapy, Japanese Red Cross Nagasaki Genbaku Hospital, 3 15 Mori machi, Nagasaki, Japan
    Cancer Chemother Pharmacol 70:645-51. 2012
    ..To determine the efficacy and toxicity of irinotecan and cisplatin with concurrent split-course thoracic radiotherapy in limited-disease (LD) SCLC, we conducted a phase II study...
  4. ncbi request reprint Phase II study of irinotecan combined with carboplatin in previously untreated non-small-cell lung cancer
    Minoru Fukuda
    Division of Respiratory Disease, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701 0192, Okayama, Japan
    Cancer Chemother Pharmacol 54:573-7. 2004
    ..Irinotecan, a topoisomerase I inhibitor, is an effective agent for non-small-cell lung cancer (NSCLC). To determine the efficacy and toxicity of irinotecan and carboplatin, we conducted a phase II study in 61 patients with advanced NSCLC...
  5. ncbi request reprint A phase I trial of carboplatin and etoposide for elderly (>or=75 year-old) patients with small-cell lung cancer
    Minoru Fukuda
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, and National Ureshino Hospital, Saga, Japan
    Cancer Chemother Pharmacol 58:601-6. 2006
    ..Then, we conducted a phase I study of carboplatin and etoposide in elderly patients, 75 years or older, with SCLC. This study aimed to determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT)...
  6. ncbi request reprint Irinotecan and cisplatin with concurrent split-course radiotherapy in locally advanced nonsmall-cell lung cancer: a multiinstitutional phase 2 study
    Minoru Fukuda
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Cancer 110:606-13. 2007
    ..The purpose was to determine the efficacy and toxicity of irinotecan and cisplatin with concurrent split-course thoracic radiotherapy (TRT) in locally advanced nonsmall-cell lung cancer...
  7. ncbi request reprint Paclitaxel and cisplatin with concurrent radiotherapy followed by surgery in locally advanced thymic carcinoma
    Minoru Fukuda
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Okayama, Japan
    Anticancer Res 27:1601-4. 2007
    ..She is currently alive and ambulatory and has remained disease-free for two years. This multimodal treatment may be a good treatment option for locally advanced thymic carcinoma...
  8. doi request reprint A phase I study of amrubicin and carboplatin for previously untreated patients with extensive-disease small cell lung cancer
    Minoru Fukuda
    Department of Medicine, Nagasaki Municipal Hospital, Nagasaki, Japan
    J Thorac Oncol 4:741-5. 2009
    ..The appropriate dose of amrubicin and carboplatin combination chemotherapy for previously untreated patients with extensive-disease (ED) SCLC has not been established...
  9. ncbi request reprint Both bronchial and vascular stenting followed by chemoradiotherapy for locally advanced non-small cell lung cancer
    Minoru Fukuda
    Division of Respiratory Diseases, Department of Medicine and Kawasaki Medical School, Okayama, Japan
    Anticancer Res 26:565-7. 2006
    ..Both endobronchial and endovascular stenting prior to antitumor therapy may be beneficial in the treatment of locally advanced cases of lung cancer...
  10. ncbi request reprint High-risk populations for nasal carriage of methicillin-resistant Staphylococcus aureus
    Minoru Fukuda
    Hirado Municipal Hospital, Hirado, Japan
    J Infect Chemother 10:189-91. 2004
    ..08, P = 0.043). The results were that advanced living in a age (>or=80, >or=90), living in a nursing home or coming from another hospital are high risk factors of nasal carriage of MRSA on hospital admission...
  11. doi request reprint Randomized phase II trial of irinotecan with paclitaxel or gemcitabine for non-small cell lung cancer: association of UGT1A1*6 and UGT1A1*27 with severe neutropenia
    Yoichi Nakamura
    Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan
    J Thorac Oncol 6:121-7. 2011
    ..A randomized phase II trial was conducted to evaluate the efficacy of irinotecan plus paclitaxel or gemcitabine for previously untreated stage IIIB or stage IV NSCLC...
  12. doi request reprint Phase I and II trials of vinorelbine with carboplatin for patients 75 years of age or older with previously untreated non-small-cell lung cancer
    Hiroshi Takatani
    Department of Respiratory Medicine, Nagasaki Municipal Medical Center, Nagasaki, Japan
    Clin Lung Cancer 13:347-51. 2012
    ..We conducted phase I and phase II trials of a combination of vinorelbine and carboplatin for patients ≥75 years of age and with advanced NSCLC...
  13. ncbi request reprint Phase I study of vinorelbine and irinotecan in previously untreated patients with advanced non-small cell lung cancer
    Nanae Tomonaga
    Department of Internal Medicine, Sasebo General Hospital, Nagasaki, Japan
    Cancer Chemother Pharmacol 62:43-9. 2008
    ..A phase I study using a combination of vinorelbine and irinotecan as first-line treatment for advanced NSCLC was done to determine the maximum tolerated dose (MTD) and the dose-limiting toxicity (DLT)...
  14. doi request reprint Pharmacokinetics of gefitinib predicts antitumor activity for advanced non-small cell lung cancer
    Yoichi Nakamura
    Second Department of Internal Medicine, Nagasaki University School of Medicine, 1 7 1 Sakamoto, Nagasaki, Japan
    J Thorac Oncol 5:1404-9. 2010
    ..We assessed the relationship between the plasma concentration of gefitinib and its efficacy in Japanese patients with advanced non-small cell lung cancer (NSCLC)...
  15. ncbi request reprint Phase I study of irinotecan and gemcitabine in previously untreated patients with advanced non-small cell lung cancer
    Hiroshi Takatani
    Department of Internal Medicine, Nagasaki Municipal Hospital, Nagasaki, Japan
    Jpn J Clin Oncol 37:353-7. 2007
    ..We conducted a phase I study of the combined use of irinotecan and gemcitabine in previously untreated patients with advanced non-small cell lung cancer to determine dose-limiting toxicities and maximum tolerated dose...
  16. ncbi request reprint Evaluation of serological tests detecting Chlamydophila pneumoniae-specific immunoglobulin M antibody
    Naoyuki Miyashita
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Okayama
    Intern Med 45:1127-31. 2006
    ..pneumoniae) detecting Chlamydophila pneumoniae-specific immunoglobulin M (IgM) antibody, we compared the assay with culturing, immunoblotting and the microimmunofluorescence (MIF) test...
  17. ncbi request reprint Pulmonary Mycobacterium intracellulare disease with a solitary pulmonary nodule detected at the onset of pneumothorax
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    J Infect Chemother 12:203-6. 2006
    ..We have reported a peculiar case of pulmonary M. intracellulare disease, detected at the onset of left secondary pneumothorax caused by pulmonary emphysema, which required differentiation from pulmonary adenocarcinoma...
  18. ncbi request reprint BCRP/ABCG2 levels account for the resistance to topoisomerase I inhibitors and reversal effects by gefitinib in non-small cell lung cancer
    Seiji Nagashima
    Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan
    Cancer Chemother Pharmacol 58:594-600. 2006
    ..The present study was designed to examine whether BCRP levels in NSCLC cells are correlated with the resistance to topoisomerase I inhibitors and the reversal effect by gefitinib...
  19. ncbi request reprint Clinical reevaluation of the QuantiFERON TB-2G test as a diagnostic method for differentiating active tuberculosis from nontuberculous mycobacteriosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, 701 0192, Japan
    Clin Infect Dis 43:1540-6. 2006
    ....
  20. ncbi request reprint [Clinical usefulness of the (1-->3)-beta-D-glucan measurement kit using the improved alkaline pretreatment method--comparison with conventional method]
    Koichiro Yoshida
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School
    Kansenshogaku Zasshi 80:701-5. 2006
    ..Then, the specificity of new MK assay was improved by using improved alkaline pretreatment reagent, without decreasing the sensitivity. Thus, the present findings indicate that the new MK assay is clinically quite useful...
  21. ncbi request reprint Usefulness of the QuantiFERON TB-2G test for the differential diagnosis of pulmonary tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Intern Med 47:237-43. 2008
    ..We prospectively evaluated the usefulness of the QuantiFERON TB-2G (QFT-2G) compared to that of tuberculin skin test (TST) as a supportive method of diagnosing pulmonary tuberculosis (TB) without invasive examinations...
  22. ncbi request reprint Transitional change in the clinical features of pulmonary tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Respiration 75:304-9. 2008
    ..An aging population, increased use of immunosuppressive therapy and an increase in patients with risk factors for tuberculosis have induced changes in the clinical features of pulmonary tuberculosis in Japan...
  23. ncbi request reprint Evaluation of the diagnostic usefulness of real-time PCR for detection of Chlamydophila pneumoniae in acute respiratory infections
    Naoyuki Miyashita
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701 0192, Japan
    J Infect Chemother 13:183-7. 2007
    ..pneumoniae acute infections and persistent ones or nasopharyngeal carriage. In addition, the detection of C. pneumoniae DNA in PBMCs does not seem to be a suitable method for the diagnosis of acute respiratory C. pneumoniae infections...
  24. ncbi request reprint [Non-specific reactions in four methods measuring (1-->3)-beta-D-glucan levels in plasma]
    Koichiro Yoshida
    Division of Repiratory Disease, Department of Medicine, Kawasaki Medical School
    Kansenshogaku Zasshi 79:329-40. 2005
    ..Finally, to measure plasma beta-glucan levels accurately, non-specific reactions should be excluded as possible by further improvement of measurement methods...
  25. ncbi request reprint Synchronus presentation of early-stage small cell carcinoma and adenocarcinoma in the same lung lobe
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Matsushima, Kurashiki
    Intern Med 45:287-91. 2006
    ....
  26. ncbi request reprint Outbreak of Chlamydophila pneumoniae infection in long-term care facilities and an affiliated hospital
    Naoyuki Miyashita
    Division of Respiratory Disease, Department of Internal Medicine and Department of Pediatrics, Kawasaki Medical School, Kurashiki City, Japan
    J Med Microbiol 54:1243-7. 2005
    ..Physicians and other health care providers in long-term care facilities should consider C. pneumoniae in the differential diagnosis of an outbreak of respiratory infection...
  27. doi request reprint Drug fever after cancer chemotherapy is most commonly observed on posttreatment days 3 and 4
    Daiki Ogawara
    Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan
    Support Care Cancer 24:615-9. 2016
    ..This study was undertaken to analyze the characteristics of fever after cancer chemotherapy in order to reduce unnecessary medical care...
  28. ncbi request reprint [Epidemic status of influenza virus between 2004-2005 and 2005-2006 at Kawasaki Medical School Hospital]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School
    Kansenshogaku Zasshi 81:435-40. 2007
    ..In spite of influenza vaccination inoculation in 20% of patients with influenza in 2004-2005 and 2005-2006, influenza spread. The prognosis of these patients, however, was comparatively good...
  29. ncbi request reprint Self-limiting pneumonia due to Chlamydia pneumoniae
    Naoyuki Miyashita
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Intern Med 44:870-4. 2005
    ..pneumoniae pneumonia is rarely encountered, although self-limiting upper respiratory tract infections due to C. pneumoniae are common. Thus, most self-limiting C. pneumoniae pneumonia may be missed when symptoms are minimal...
  30. ncbi request reprint Usefulness of QuantiFERON TB-2G, a diagnostic method for latent tuberculosis infection, in a contact investigation of health care workers
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki
    Intern Med 46:1543-9. 2007
    ..To evaluate the usefulness of QuantiFERON TB-2G (QFT-2G) for detecting latent tuberculosis infection (LTBI) in a contact investigation of health care workers...
  31. ncbi request reprint [Current status of patients discharging Mycobacterium tuberculosis after admission to Kawasaki Medical School Hospital]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki shi, Okayama 701 0192, Japan
    Kekkaku 80:57-62. 2005
    ..To investigate the current status of patients with tuberculosis in Kawasaki Medical School Hospital which has closed tuberculosis isolation ward and review the nosocomial tuberculosis infection control...
  32. ncbi request reprint Chronic necrotizing pulmonary aspergillosis as a complication of pulmonary Mycobacterium avium complex disease
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Respirology 11:809-13. 2006
    ..To investigate the characteristic clinical features of chronic necrotizing pulmonary aspergillosis (CNPA) as a complication of pulmonary Mycobacterium avium complex (MAC) disease...
  33. ncbi request reprint Community-acquired pneumonia in Japan: a prospective ambulatory and hospitalized patient study
    Naoyuki Miyashita
    Division of Respiratory Disease, Department of Internal Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki City, Okayama 701 0192, Japan
    J Med Microbiol 54:395-400. 2005
    ..pneumoniae and Haemophilus influenzae was higher among the hospitalized patients. Recognition of these results will allow prompt and appropriate antimicrobial therapy to be provided using Japanese CAP guidelines...
  34. ncbi request reprint Inflammatory pseudotumor of the lung: clinicopathological analysis in seven adult patients
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    Int J Clin Oncol 11:461-6. 2006
    ..As the origin and pathology of inflammatory pseudotumor is not clearly understood, there has recently been some confusion regarding the diagnosis of inflammatory pseudotumor...
  35. doi request reprint Pulmonary mucormycosis (Cunninghamella bertholletiae) with cavitation diagnosed using ultra-thin fibre-optic bronchoscopy
    Shin ichi Yagi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Respirology 13:312-4. 2008
    ..bertholletiae) complicating an immunocompromised state was diagnosed. Ultra-thin bronchoscopy is useful to diagnose complex pulmonary infections and more research is needed to verify its clinical indications and utility...
  36. doi request reprint Pharmacokinetic parameters of gefitinib predict efficacy and toxicity in patients with advanced non-small cell lung cancer harboring EGFR mutations
    Kosuke Mizoguchi
    Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan
    Cancer Chemother Pharmacol 78:377-82. 2016
    ..The relationship between plasma concentration and antitumor activity of gefitinib was assessed in patients with advanced non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations...
  37. doi request reprint Phase I/II study of amrubicin and nedaplatin in patients with untreated, advanced, non-small cell lung cancer
    Daiki Ogawara
    Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan
    Chemotherapy 60:180-4. 2014
    ..9, 11.4 and 11.4% of cycles, respectively. Febrile neutropenia occurred in 5 cycles (3.9%) and all cases were manageable. The recommended dose of this combination is well tolerated and effective in patients with advanced NSCLC...
  38. doi request reprint A phase II study of amrubicin and carboplatin for previously untreated patients with extensive-disease small cell lung cancer
    Takaya Ikeda
    Department of Medicine, Sasebo General Hospital, Nagasaki, Japan
    Cancer Chemother Pharmacol 74:497-502. 2014
    ..Amrubicin is active in the treatment of extensive-disease small cell lung cancer (ED-SCLC), and carboplatin is an analogue of cisplatin with less non-hematological toxicity...
  39. doi request reprint Prolongation of overall survival in advanced lung adenocarcinoma patients with the XAGE1 (GAGED2a) antibody
    Yoshihiro Ohue
    Department of Respiratory Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Clin Cancer Res 20:5052-63. 2014
    ..The cancer/testis antigen XAGE1 (GAGED2a) is expressed in approximately 40% of advanced lung adenocarcinomas. We investigated the clinical relevance of the XAGE1 (GAGED2a) immune responses in patients with advanced lung adenocarcinoma...
  40. doi request reprint Spontaneous antibody, and CD4 and CD8 T-cell responses against XAGE-1b (GAGED2a) in non-small cell lung cancer patients
    Yoshihiro Ohue
    Department of Respiratory Medicine, Kawasaki Medical School, Kurashiki, Japan
    Int J Cancer 131:E649-58. 2012
    ..The CD8 T-cell clone showed cytotoxicity against a tumor expressing XAGE-1b (GAGED2a) and the appropriate HLA class I allele. These findings establish XAGE-1b (GAGED2a) as a promising target for a lung cancer vaccine...
  41. ncbi request reprint Four cases of pulmonary Mycobacterium avium intracellulare complex presenting as a solitary pulmonary nodule and a review of other cases in Japan
    Yoshihiro Kobashi
    Department of Medicine, Division of Respiratory Diseases, Kawasaki Medical School, Kawasaki, Japan
    Respirology 11:317-21. 2006
    ..To evaluate clinical findings of patients with a solitary pulmonary nodule in Japan caused by pulmonary Mycobacterium avium complex (MAC) disease...
  42. ncbi request reprint An indeterminate QuantiFERON TB-2G response for miliary tuberculosis, due to severe pancytopenia
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701 0192, Japan
    J Infect Chemother 13:414-7. 2007
    ..This patient was treated with antituberculous drugs 3 days after admission, but he died of multiple organ failure 6 days after admission...
  43. doi request reprint The definition of healthcare-associated pneumonia (HCAP) is insufficient for the medical environment in Japan: a comparison of HCAP and nursing and healthcare-associated pneumonia (NHCAP)
    Norihito Kaku
    Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan
    J Infect Chemother 19:70-6. 2013
    ..Therefore, there is a need to change the definition of HCAP according to the medical environment in Japan...
  44. doi request reprint Detection of Legionella pneumophila serogroup 1 in blood cultures from a patient treated with tumor necrosis factor-alpha inhibitor
    Norihito Kaku
    Department of Internal Medicine, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan
    J Infect Chemother 19:166-70. 2013
    ..In consideration of the increased frequency of TNF-α inhibitors, we may need to recognize anew that L. pneumophila might be a pathogen of severe community-acquired pneumonia...
  45. ncbi request reprint Coexistence of metastatic lung cancer and pulmonary tuberculosis diagnosed in the same cavity
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701 0192, Japan
    Int J Clin Oncol 10:366-70. 2005
    ..We report a rare case of the coexistence of metastatic lung cancer originating from tongue cancer and active pulmonary tuberculosis diagnosed in the same large cavitary lesion...
  46. pmc Phase I study of irinotecan for previously treated lung cancer patients with the UGT1A1*28 or *6 polymorphism: Results of the Lung Oncology Group in Kyushu (LOGIK1004A)
    Minoru Fukuda
    Clinical Oncology Center, Nagasaki University Hospital, Nagasaki, Japan
    Thorac Cancer . 2016
    ..This study was conducted to determine the maximum tolerated dose (MTD) of irinotecan chemotherapy according to the UGT1A1 genotype in previously treated lung cancer patients with the UGT1A1 *28 or UGT1A1 *6 polymorphism...
  47. pmc Primary Mediastinal Large B-cell Lymphoma Exhibiting Endobronchial Involvement
    Midori Shimada
    Department of Respiratory Medicine, Japanese Red Cross Nagasaki Genbaku Hospital, Japan
    Intern Med 55:3147-3150. 2016
    ..Fiberoptic bronchoscopy showed a white-tinged irregularly shaped endobronchial tumor accompanied by capillary vessel dilation in the left upper lobar bronchus. Taken together, these findings resulted in a diagnosis of PMLBCL...
  48. doi request reprint Localized ground glass opacities with multiple pulmonary small cysts in adult T-cell leukemia or lymphoma: an "alloy wheel" appearance
    Aya Sakashita
    Department of Radiology, Nagasaki University Hospital, Nagasaki, Japan
    J Thorac Imaging 24:321-4. 2009
    ....
  49. ncbi request reprint [A case of pulmonary adenosquamous cell carcinoma with thin-wall cavities]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School
    Nihon Kokyuki Gakkai Zasshi 43:59-62. 2005
    ..Herein, we have reported a rare case of histological diagnosis of pulmonary adenosquamous cell carcinoma with cavity formation...
  50. doi request reprint Comparison between solid component size on thin-section CT and pathologic lymph node metastasis and local invasion in T1 lung adenocarcinoma
    Hideyuki Hayashi
    Unit of Translational Medicine, Department of Clinical Oncology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki, 852 8501, Japan
    Jpn J Radiol . 2017
    ..To correlate the tumor size and solid component size on thin-section CT (TS-CT) with pathological findings including lymph node (LN) metastasis and local invasion in T1 lung adenocarcinoma...
  51. ncbi request reprint [Anticancer drugs and ABC transporters]
    Mikio Oka
    Division of Respiratory Diseases, Dept of Medicine, Kawasaki Medical School, Okayama, Japan
    Gan To Kagaku Ryoho 32:585-92. 2005
    ..Additionally, polymorphism of ABC genes affects pharmacokinetics, drug effectiveness, and adverse events. Thus, ABC transporters are clinically important molecules, and much information is needed in the clinic...
  52. ncbi request reprint Induction chemotherapy with cisplatin, vinorelbine, and mitomycin-C followed by surgery for patients with pathologic N2 non-small-cell lung cancer
    Shinji Akamine
    Department of Chest Surgery, Oita Prefectural Hospital, Oita, Japan
    Clin Lung Cancer 9:44-50. 2008
    ..We performed a phase II feasibility study of induction chemotherapy followed by surgery for patients with pathologic N2 NSCLC...
  53. ncbi request reprint A distinctive set of genes is upregulated during the inflammation-carcinoma sequence in mouse stomach infected by Helicobacter felis
    Motohiro Kobayashi
    Glycobiology Program, Cancer Research Center, Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Histochem Cytochem 55:263-74. 2007
    ..These results as a whole indicate that H. felis induces HEV-like vessels and inflammation-associated chemokines and chemokine receptors, followed by adenocarcinoma formation...
  54. ncbi request reprint Clinical utility of quantitative RT-PCR targeted to alpha1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer
    Satoshi Ishizone
    Department of Surgery, Shinshu University School of Medicine, Asahi 3 1 1, Matsumoto 390 8621, Japan
    Cancer Sci 97:119-26. 2006
    ..These results suggest that quantitative analysis of alpha4GnT mRNA expressed in the mononuclear cell fraction of peripheral blood will contribute to the detection of pancreatic cancer...
  55. ncbi request reprint Cell type-specific roles of carbohydrates in tumor metastasis
    Shihao Chen
    Glycobiology Program, Cancer Research Center, The Burnham Institute for Medical Research, La Jolla, CA, USA
    Methods Enzymol 416:371-80. 2006
    ....
  56. ncbi request reprint Influences of the lysosomal associated membrane proteins (Lamp-1, Lamp-2) and Mac-2 binding protein (Mac-2-BP) on the prognosis of pancreatic carcinoma
    Beat M Künzli
    Department of Visceral and Transplantation Surgery, University of Bern, Inselspital, Bern, Switzerland
    Cancer 94:228-39. 2002
    ..The authors studied the expression of Lamp-1, Lamp-2, and Mac-2-BP in pancreatic carcinoma and evaluated their influence on patient prognosis...
  57. ncbi request reprint [Application of preoperative risk severity evaluation system (EuroSCORE=European system for cardiac operative risk evaluation) for cardiac operative patients]
    Minoru Fukuda
    Department of Anesthesia, Shonan Kamakura Hospital, Kamakura 247 8533
    Masui 53:1149-54. 2004
    ..We evaluated a scoring system for the prediction of postoperative morbidity and mortality in Japanese cardiac surgical patients...
  58. ncbi request reprint A peptide mimic of selectin ligands abolishes in vivo inflammation but has no effect on the rat heart allograft survival1
    Risto Renkonen
    Department of Bacteriology and Immunology, Pathology, and Transplantation Laboratory, Haartman Institute, University of Helsinki, Finland
    Transplantation 74:2-6. 2002
    ..These data indicate that the intensity of inflammation related to the allograft rejection does not correlate to the graft survival...
  59. ncbi request reprint The histone deacetylase inhibitor FR901228 induces caspase-dependent apoptosis via the mitochondrial pathway in small cell lung cancer cells
    Seiji Doi
    Division of Molecular and Clinical Microbiology, Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
    Mol Cancer Ther 3:1397-402. 2004
    ..Considering the possible contributions of BCL-2 and BCL-XL to multidrug resistance, FR901228 is a promising agent in the treatment of refractory as well as primary SCLC tumors...
  60. ncbi request reprint Gene transfer of alpha1,3-fucosyltransferase increases tumor growth of the PC-3 human prostate cancer cell line through enhanced adhesion to prostatic stromal cells
    Yasuo Inaba
    Department of Urology, Tohoku University School of Medicine, Sendai, Japan
    Int J Cancer 107:949-57. 2003
    ..These results suggest that prostate cancer cells gain aggressiveness through adhesive interaction with prostatic stromal cells by a novel mechanism involving sialyl Lewis X...
  61. ncbi request reprint Sialyl Lewis X-dependent lung colonization of B16 melanoma cells through a selectin-like endothelial receptor distinct from E- or P-selectin
    Jianing Zhang
    Glycobiology Program, Cancer Research Center, The Burnham Institute, La Jolla, California 92037, USA
    Cancer Res 62:4194-8. 2002
    ..These results indicate that the IELLQAR peptide receptor expressed in the lung vasculature plays a major role in sialyl Lewis X-dependent cancer cells targeting to the lung...
  62. ncbi request reprint Usefulness of the real-time reverse transcription-polymerase chain reaction assay targeted to alpha1,4-N-acetylglucosaminyltransferase for the detection of gastric cancer
    Fumiaki Shimizu
    Department of Laboratory Medicine, Shinshu University School of Medicine, Matsumoto, Japan
    Lab Invest 83:187-97. 2003
    ..These results altogether indicate that the quantitative analysis of alpha4GnT mRNA expressed in the peripheral blood is useful for the detection and, possibly, monitoring of gastric cancer...
  63. pmc Natural killer cells attack tumor cells expressing high levels of sialyl Lewis x oligosaccharides
    Chikara Ohyama
    Department of Urology, Akita University School of Medicine, Akita 010 8543, Japan
    Proc Natl Acad Sci U S A 99:13789-94. 2002
    ....