K Yamada

Summary

Affiliation: Fujita Health University
Country: Japan

Publications

  1. doi request reprint Stimulus in the form of rotation and shaking of a platform and its effect on the formation of trabecular bone in the lumbar vertebrae of mice
    Kouji Yamada
    School of Health Sciences, Fujita Health University, 1 98, Kutsukake cho, Toyoake, Aichi, 470 1192, Japan
    Aging Clin Exp Res 25:625-32. 2013
  2. pmc DNA secondary structure is influenced by genetic variation and alters susceptibility to de novo translocation
    Takema Kato
    Division of Molecular Genetics, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi 470 1192, Japan
    Mol Cytogenet 4:18. 2011
  3. doi request reprint Cubital fossa venipuncture sites based on anatomical variations and relationships of cutaneous veins and nerves
    Kouji Yamada
    Faculty of Rehabilitation, School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan
    Clin Anat 21:307-13. 2008
  4. ncbi request reprint Expression levels of Rab2, a G protein, and Bag-1, a Bcl-2 binding protein are controlled by withdrawal of nicotine from cultured pheochromocytoma PC12 cells
    K Yamada
    School of Health Science, Fujita Health University, Toyoake, Aichi, Japan
    J Neural Transm (Vienna) 112:633-9. 2005
  5. ncbi request reprint Increase of transcriptional levels of egr-1 and nur77 genes due to both nicotine treatment and withdrawal in pheochromocytoma cells
    N Ichino
    Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi 470 1192, Japan
    J Neural Transm 109:1015-22. 2002
  6. ncbi request reprint Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene
    H Ishiguro
    Institute for Comprehensive Medical Science, Fujita Health University, Toyoake Aichi 470 1192, Japan
    J Neurosci Res 65:289-97. 2001
  7. ncbi request reprint Functional and high level expression of human dopamine beta-hydroxylase in transgenic mice
    K Kobayashi
    Institute for Comprehensive Medical Science, School of Medicine, Fujita Health University, Aichi, Japan
    J Biol Chem 269:29725-31. 1994
  8. doi request reprint Molecular analysis of two enzyme genes, HPRT1 and PRPS1, causing X-linked inborn errors of purine metabolism
    Y Yamada
    Department of Genetics, Institute for Developmental Research, Aichi Human Service Center, Kasugai, Aichi, Japan
    Nucleosides Nucleotides Nucleic Acids 29:291-4. 2010
  9. ncbi request reprint Characterization of the human NTAK gene structure and distribution of the isoforms for rat NTAK mRNA
    K Yamada
    Institute for Comprehensive Medical Science, Fujita Health University, Aichi 470 1192, Toyoake, Japan
    Gene 255:15-24. 2000
  10. ncbi request reprint Clinical significance of IgE-binding activity to enzymatic digests of ovomucoid in the diagnosis and the prediction of the outgrowing of egg white hypersensitivity
    A Urisu
    Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
    Int Arch Allergy Immunol 120:192-8. 1999

Collaborators

Detail Information

Publications73

  1. doi request reprint Stimulus in the form of rotation and shaking of a platform and its effect on the formation of trabecular bone in the lumbar vertebrae of mice
    Kouji Yamada
    School of Health Sciences, Fujita Health University, 1 98, Kutsukake cho, Toyoake, Aichi, 470 1192, Japan
    Aging Clin Exp Res 25:625-32. 2013
    ..A new form of therapeutic exercise that mitigates the abrupt decrease in bone density in postmenopausal women must soon be developed so that those problems can be avoided...
  2. pmc DNA secondary structure is influenced by genetic variation and alters susceptibility to de novo translocation
    Takema Kato
    Division of Molecular Genetics, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi 470 1192, Japan
    Mol Cytogenet 4:18. 2011
    ..These studies were designed to determine whether PATRR polymorphisms affect DNA secondary structure, thus leading to variation in translocation frequency...
  3. doi request reprint Cubital fossa venipuncture sites based on anatomical variations and relationships of cutaneous veins and nerves
    Kouji Yamada
    Faculty of Rehabilitation, School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan
    Clin Anat 21:307-13. 2008
    ..8%). The distribution of cutaneous veins and nerves widely varies, and while no single area suitable for all individuals was identified, puncture of the MCBV near the cephalic vein is the least likely to cause nerve damage...
  4. ncbi request reprint Expression levels of Rab2, a G protein, and Bag-1, a Bcl-2 binding protein are controlled by withdrawal of nicotine from cultured pheochromocytoma PC12 cells
    K Yamada
    School of Health Science, Fujita Health University, Toyoake, Aichi, Japan
    J Neural Transm (Vienna) 112:633-9. 2005
    ..The present results suggest that such changes may also occur in individuals during abstaining from smoking and be related to the withdrawal symptoms experienced after smokers stop smoking...
  5. ncbi request reprint Increase of transcriptional levels of egr-1 and nur77 genes due to both nicotine treatment and withdrawal in pheochromocytoma cells
    N Ichino
    Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi 470 1192, Japan
    J Neural Transm 109:1015-22. 2002
    ..These results suggest that expressional levels of Egr-1 and Nur77 proteins in neural cells may affect the transcriptional activity of late-response genes after nicotine withdrawal...
  6. ncbi request reprint Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene
    H Ishiguro
    Institute for Comprehensive Medical Science, Fujita Health University, Toyoake Aichi 470 1192, Japan
    J Neurosci Res 65:289-97. 2001
    ..The HD model mouse may therefore have advantages for investigations of molecular mechanisms underlying instability of CAG repeats...
  7. ncbi request reprint Functional and high level expression of human dopamine beta-hydroxylase in transgenic mice
    K Kobayashi
    Institute for Comprehensive Medical Science, School of Medicine, Fujita Health University, Aichi, Japan
    J Biol Chem 269:29725-31. 1994
    ..These transgenic mice with the minigene construct provide one approach to study the mechanisms underlying biogenesis of the DBH polypeptide and regulation of norepinephrine synthesis...
  8. doi request reprint Molecular analysis of two enzyme genes, HPRT1 and PRPS1, causing X-linked inborn errors of purine metabolism
    Y Yamada
    Department of Genetics, Institute for Developmental Research, Aichi Human Service Center, Kasugai, Aichi, Japan
    Nucleosides Nucleotides Nucleic Acids 29:291-4. 2010
    ..In these four patients, we also performed molecular analysis of PRPS1, but no mutations in PRPP synthetase were found...
  9. ncbi request reprint Characterization of the human NTAK gene structure and distribution of the isoforms for rat NTAK mRNA
    K Yamada
    Institute for Comprehensive Medical Science, Fujita Health University, Aichi 470 1192, Toyoake, Japan
    Gene 255:15-24. 2000
    ..Potential regulatory regions included consensus binding sites for AP-2, TF-IIIA, Sp-1, and YY-1 located in the 5'-flanking region of the NTAK gene...
  10. ncbi request reprint Clinical significance of IgE-binding activity to enzymatic digests of ovomucoid in the diagnosis and the prediction of the outgrowing of egg white hypersensitivity
    A Urisu
    Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
    Int Arch Allergy Immunol 120:192-8. 1999
    ..The measurements of these antibodies are not necessarily efficient for the diagnosis or the prediction of the outcome of egg allergy in children...
  11. ncbi request reprint Genomic organization, chromosomal localization, and the complete 22 kb DNA sequence of the human GCMa/GCM1, a placenta-specific transcription factor gene
    K Yamada
    Institute for Comprehensive Medical Science, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan
    Biochem Biophys Res Commun 278:134-9. 2000
    ..A DNA motif for GCM protein binding exists in the 5'-flanking region that is highly homologous with that of the mouse gene. The location of this gene was mapped to chromosome 6 using fluorescence in situ hybridization...
  12. ncbi request reprint Mutations in the hypoxanthine guanine phosphoribosyltransferase gene (HPRT1) in Asian HPRT deficient families
    Y Yamada
    Department of Genetics, Inst Developmental Res, Aichi Human Service Center, Aichi, Japan
    Nucleosides Nucleotides Nucleic Acids 23:1169-72. 2004
    ....
  13. ncbi request reprint A GCM motif protein is involved in placenta-specific expression of human aromatase gene
    K Yamada
    Institute for Comprehensive Medical Science, School of Medicine, Toyoake, Aichi 470 1192, Japan
    J Biol Chem 274:32279-86. 1999
    ....
  14. doi request reprint Comparative study of low-dose pioglitazone or metformin treatment in Japanese diabetic patients with metabolic syndrome
    T Kato
    Department of Internal Medicine, Aichi Koseiren Toyota Kosei Hospital, Aichi, Japan
    Exp Clin Endocrinol Diabetes 117:593-9. 2009
    ....
  15. ncbi request reprint Phenotypic changes of AADC-only immunopositive premammillary neurons in the brain of laboratory shrew Suncus murinus by systemic administration of monoamine precursors
    N Karasawa
    Department of Anatomy, Fujita Health University, Aichi, Japan
    Neurosci Lett 179:65-70. 1994
    ....
  16. ncbi request reprint Biochemical and molecular genetic analyses on placental aromatase (P-450AROM) deficiency
    N Harada
    Division of Molecular Genetics, Fujita Health University, Aichi, Japan
    J Biol Chem 267:4781-5. 1992
    ..During the transient expression in COS-7 cells, the aromatase cDNA of the patient was found to produce a protein with a trace of activity. This is the first report of a genetic defect for aromatase deficiency...
  17. ncbi request reprint Gene expression profile in rat renal isografts from brain dead donors
    M Kusaka
    Department of Urology, Development Center for Targeted and Minimally Invasive Diagnosis and Treatment, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
    Transplant Proc 37:364-6. 2005
    ..In this study, we performed genome-wide analysis for differential gene expression in kidney isografts from BD donors. Their gene expressions were compared with those from living sources...
  18. ncbi request reprint A morphological and immunohistochemical study of the ultimobranchial body in the Japanese lizard and the snake
    K Yamada
    Department of Anatomy, School of Health Sciences, Fujita Health University, Toyoake, Aichi 470 1192, Japan
    Okajimas Folia Anat Jpn 78:161-8. 2001
    ..The findings suggest that the configuration of amino acid in the Japanese lizard calcitonin and snake calcitonin are similar to that of pig calcitonin, and the reptile and the birds is a boundary of the tyrosine hydroxylase existence...
  19. ncbi request reprint Allergen-specific helper T cell response in patients with cow's milk allergy: Simultaneous analysis of proliferation and cytokine production by carboxyfluorescein succinimidyl ester dilution assay
    I Tsuge
    Department of Pediatrics, School of Medicine, Fujita Health University, Aichi Ken, Japan
    Clin Exp Allergy 36:1538-45. 2006
    ..The role of antigen-specific T cells in the allergic reaction to cow's milk or in tolerance induction is not yet fully understood...
  20. ncbi request reprint Targeted disruption of the tyrosine hydroxylase locus results in severe catecholamine depletion and perinatal lethality in mice
    K Kobayashi
    Institute for Comprehensive Medical Science, School of Medicine, Fujita Health University, Aichi, Japan
    J Biol Chem 270:27235-43. 1995
    ..These results indicate that TH is essential for survival of the animals during the late gestational development and after birth...
  21. ncbi request reprint Ontogeny of aromatase messenger ribonucleic acid in mouse brain: fluorometrical quantitation by polymerase chain reaction
    N Harada
    Division of Molecular Genetics, Fujita Health University, Aichi, Japan
    Endocrinology 131:2306-12. 1992
    ....
  22. ncbi request reprint Sp family members stimulate transcription of the hex gene via interactions with GC boxes
    E Kikkawa
    Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa-ku, Nagoya 464-8601, Japan
    J Biochem 130:885-91. 2001
    ..Thus, we conclude that Sp1 and Sp3 stimulate transcription of the Hex gene in both MH(1)C(1) and K562 cells...
  23. ncbi request reprint Cloning and functional expression of an E box-binding protein from rat granulosa cells
    K Yamada
    Department of Biochemistry, Fukui Medical University, Shimoaizuki, Matsuoka, Fukui 910 1193 and CREST, JST Japan Science and Technology, Japan
    Biol Reprod 64:1315-9. 2001
    ..Thus, we report molecular cloning, expression, and functional characterization of full-length rat USF2 cDNA...
  24. ncbi request reprint Functional correction of fanconi anemia group C hematopoietic cells by the use of a novel lentiviral vector
    K Yamada
    UNC Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Mol Ther 3:485-90. 2001
    ..This is the first description of lentiviral correction of FA cells and suggests that lentiviral vectors may be useful for FA gene transfer...
  25. ncbi request reprint Successful surgical treatment of renal cell carcinoma in a transplanted kidney from a cadaveric donor: report of a case
    Y Gunji
    Department of Surgery (II, Chiba University School of Medicine, Japan
    Surg Today 31:374-7. 2001
    ..An en bloc radical transplant nephrectomy was performed, and he has subsequently remained stable on hemodialysis for 3 years without any sign of recurrence...
  26. ncbi request reprint Alterations in the expression of the AQP family in cultured rat astrocytes during hypoxia and reoxygenation
    N Yamamoto
    Department of Bioregulation Research, Nagoya City University Medical School, Mizuho-ku, 467-8601, Nagoya, Japan
    Brain Res Mol Brain Res 90:26-38. 2001
    ..These results suggest that AQP5 may be one of the candidates for inducing the intracranial edema in the CNS after ischemia injury...
  27. ncbi request reprint Assignment of the ATBF1 transcription factor gene (Atbf1) to mouse chromosome band 8E1 by in situ hybridization
    K Yamada
    Cytogenetics Laboratory, Graduate School of Environmental Earth Science, Hokkaido University, Sapporo, Japan
    Cytogenet Cell Genet 75:30-1. 1996
  28. ncbi request reprint Sequence analysis of candidate genes for common susceptibility to type 1 and type 2 diabetes in mice
    K Yamada
    Department of Geriatric Medicine, Osaka University Graduate School of Medicine, Japan
    Endocr J 48:241-7. 2001
    ..The coding sequence of Txn was identical in the three strains. These data suggest that neither of the two genes is a common susceptiblity gene between type 1 and type 2 diabetes in mice...
  29. ncbi request reprint Molecular cloning and functional characterization of chicken toll-like receptors. A single chicken toll covers multiple molecular patterns
    A Fukui
    Department of Immunology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Nakamichi, Higashinari ku, Osaka 537 8511, Japan
    J Biol Chem 276:47143-9. 2001
    ..In oviparous animals, the duplicated TLRs in the pattern-recognition system may function for host-pathogen discrimination in a manner that is distinct from that in mammals...
  30. ncbi request reprint Lack of association between hepatocyte nuclear factor-1beta gene and common forms of type 2 diabetes in the Japanese population
    N Babaya
    Department of Geriatric Medicine, Osaka University Graduate School of Medicine, Suita, Japan
    Diabetes Nutr Metab 14:220-4. 2001
    ..These results suggest that mutations in the HNF-1beta gene derived from a limited number of founders are not a major cause of common forms of Type 2 diabetes, even in the genetically homogeneous Japanese population...
  31. ncbi request reprint Mapping and promoter sequencing of HNF-1beta gene in diabetes-prone and -resistant mice
    H Ueda
    Department of Geriatric Medicine, Osaka University Medical School, 2 2 Yamadaoka, Suita, 565 0871, Osaka, Japan
    Diabetes Res Clin Pract 53:67-71. 2001
    ..3 cM)-Tcf2-(0.5 cM)-D11MIT195. A variant with insertion of C between -205 and -204 in the promoter region of Tcf2 was identified in NSY mice, but not NOD and C3H/He mice...
  32. ncbi request reprint Predominant expression of human zic in cerebellar granule cell lineage and medulloblastoma
    N Yokota
    Molecular Neurobiology Laboratory, Tsukuba Life Science Center, Institute of Physical and Chemical Research RIKEN, Ibaraki, Japan
    Cancer Res 56:377-83. 1996
    ..These findings suggest that Zic is a potential biomarker for medulloblastoma as well as the human cerebellar granule cell lineage...
  33. ncbi request reprint Human high-affinity Fc gamma RI (CD64) gene mapped to chromosome 1q21.2-q21.3 by fluorescence in situ hybridization
    S Takai
    Division of Genetics, National Medical Center, Tokyo, Japan
    Hum Genet 93:13-5. 1994
    ..The human Fc gamma RI (CD64) gene has been assigned to human chromosome 1q21.2-q21.3 using R-banded human (pro)metaphase chromosomes...
  34. ncbi request reprint Molecular cloning of the human histamine H1 receptor gene
    H Fukui
    Department of Pharmacology II, Faculty of Medicine, Osaka University, Suita, Japan
    Biochem Biophys Res Commun 201:894-901. 1994
    ..5-kilobase nucleotides was present in the brain. H1 receptor mRNA was most abundant in the placenta. The human H1 receptor gene was mapped to the chromosome 3p25 by the fluorescence in situ hybridization method...
  35. ncbi request reprint Assignment of the human dihydropyrimidine dehydrogenase gene (DPYD) to chromosome region 1p22 by fluorescence in situ hybridization
    S Takai
    Department of Genetics, International Medical Center of Japan, Tokyo
    Genomics 24:613-4. 1994
  36. ncbi request reprint Chromosomal localization of the human ECT2 proto-oncogene to 3q26.1-->q26.2 by somatic cell analysis and fluorescence in situ hybridization
    S Takai
    Department of Genetics, International Medical Center of Japan
    Genomics 27:220-2. 1995
  37. ncbi request reprint Expression of the human cGMP-dependent protein kinase II gene is lost upon introduction of SV40 T antigen or immortalization in human cells
    M Fujii
    Institute of Molecular and Cellular Biosciences, University of Tokyo, Japan
    FEBS Lett 375:263-7. 1995
    ..Also in various immortalized cell lines tested, the gene was not expressed. In normal diploid fibroblasts, the gene was constitutively expressed during cell-cycle and population doubling levels (PDLs)...
  38. ncbi request reprint Isolation and characterization of the human pyruvate kinase M gene
    M Takenaka
    Department of Nutrition and Physiological Chemistry, Osaka University Medical School, Japan
    Eur J Biochem 198:101-6. 1991
    ..Long stretches of conserved regions were found in the introns around the M1-specific and M2-specific exons, suggesting that these regions may be involved in the alternative splicing machinery...
  39. ncbi request reprint Human TNF receptor-associated factor 5 (TRAF5): cDNA cloning, expression and assignment of the TRAF5 gene to chromosome 1q32
    H Nakano
    Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan
    Genomics 42:26-32. 1997
    ..Fluorescence in situ hybridization confirmed regional localization to human chromosome 1q32...
  40. ncbi request reprint A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4
    S Higashiyama
    Department of Biochemistry, Osaka University Medical School, Suita
    J Biochem 122:675-80. 1997
    ..Thus, NTAK appears to be a new member of the EGF family displaying neuregulin properties...
  41. ncbi request reprint Domain-specific mutations in TGFB1 result in Camurati-Engelmann disease
    A Kinoshita
    Department of Human Genetics, Nagasaki University School of Medicine, Nagasaki, Japan
    Nat Genet 26:19-20. 2000
    ..1-q13.3, which two other groups confirmed. As the human transforming growth factor-1 gene (TGFB1) is located within this interval, we considered it a candidate gene for CED...
  42. ncbi request reprint Human ZHX1: cloning, chromosomal location, and interaction with transcription factor NF-Y
    K Yamada
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, 707 Light Hall, Nashville, Tennessee, 37232 0615, USA
    Biochem Biophys Res Commun 261:614-21. 1999
    ..Both transcripts were expressed ubiquitously, although the 5-kilobase transcript is of greater abundance in most tissues examined. The human ZHX1 gene is located on chromosome 8q, between markers CHCL.GATA50B06 and CHLC. GATA7G07...
  43. ncbi request reprint Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3beta
    J C Wang
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0615, USA
    J Biol Chem 275:18418-23. 2000
    ..These results lead us to suggest that TLE proteins could influence the expression of mammalian genes regulated by HNF3...
  44. ncbi request reprint Structure and chromosome mapping of the human SIX4 and murine Six4 genes
    H Ozaki
    Department of Biology, Jichi Medical School, Tochigi, Japan
    Cytogenet Cell Genet 87:108-12. 1999
    ..The structure, including the 5' upstream region of both genes, was well conserved suggesting the conserved function and regulation of these genes. Human SIX4 was mapped to chromosome 14q23...
  45. ncbi request reprint Identification, characterization and mapping of the human ZIS (zinc-finger, splicing) gene
    M Nakano
    Department of Human Genetics, Nagasaki University School of Medicine, Sakamoto 1 12 4, Nagasaki, Japan
    Gene 225:59-65. 1998
    ..Furthermore, the expression patterns of the two genes in tissues are similar each other. Thus, the human ZIS may act as a transcriptional factor to regulate transcription and/or splicing, as does the rat Zis...
  46. ncbi request reprint Assignment of the human ATBF1 transcription factor gene to chromosome 16q22.3-q23.1
    K Yamada
    Cytogenetics Laboratory, Graduate School of Environmental Earth Science, Faculty of Science, Hokkaido University, Sapporo, Japan
    Genomics 29:552-3. 1995
  47. ncbi request reprint Identification of proteins that interact with NF-YA
    K Yamada
    Department of Biochemistry, Fukui Medical University, Japan
    FEBS Lett 460:41-5. 1999
    ..Two different domains of NF-YA, a glutamine-rich region and a serine/threonine-rich region, are necessary for the interactions with ZHX1 and SRF, respectively...
  48. ncbi request reprint Changes in occlusal force and occlusal contact area after active orthodontic treatment: a pilot study using pressure-sensitive sheets
    M H Sultana
    Division of Orthodontics, Department of Oral Biological Science, Section for Oral Life Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
    J Oral Rehabil 29:484-91. 2002
    ..These results suggested that balanced OcFr and OcAr might be obtained during and after retention, due to the settling of molars that had been discluded by active orthodontic treatment...
  49. ncbi request reprint Mouse islet cell lysis mediated by interleukin-1-induced Fas
    K Yamada
    Department of Medicine, Kurume University School of Medicine, Japan
    Diabetologia 39:1306-12. 1996
    ..beta-TC1 cells also expressed Fas mRNA when exposed to IL-1 alpha or IL-1 alpha plus interferon-gamma. These observations suggest that Fas-mediated apoptosis may be a mechanism of islet cell death in autoimmune insulitis...
  50. pmc cDNA cloning and expression of rat homeobox gene, Hex, and functional characterization of the protein
    T Tanaka
    Department of Biochemistry, Osaka University Medical School, Suita, Osaka 565 0871, Japan
    Biochem J 339:111-7. 1999
    ..These results indicate that Hex functions as a transcriptional repressor and may be involved in the differentiation and/or maintenance of the differentiated state in hepatocytes...
  51. ncbi request reprint Molecular study of eight Japanese cases of glucose-6-phosphate dehydrogenase deficiency by nonradioisotopic single-strand conformation polymorphism analysis
    A Hirono
    Okinaka Memorial Institute for Medical Research, Tokyo, Japan
    Blood 83:3363-8. 1994
    ..Because it is easy and requires no special apparatus, this modified method will be useful for screening mutations in the G6PD gene...
  52. ncbi request reprint Mapping of the human C3G gene coding a guanine nucleotide releasing protein for Ras family to 9q34.3 by fluorescence in situ hybridization
    S Takai
    Department of Genetics, Research Institute, International Medical Center, Tokyo, Japan
    Hum Genet 94:549-50. 1994
    ..C3G was originally identified as one of the CRK-binding proteins, similar to c-abl (9q34.1). Our result suggests that the downstream factors of Crk are localized in close proximity on chromosome 9...
  53. ncbi request reprint Genome-wide profiling of promoter methylation in human
    I Hatada
    Laboratory of Genome Science, Biosignal Genome Resource Center, Department of Molecular and Cellular Biology, Gunma University, Maebashi, Japan
    Oncogene 25:3059-64. 2006
    ..Genome-wide analysis of hypomethylated promoter sequences in cancer demonstrated low CG/GC ratio of these sequences, suggesting that CpG-poor genes are sensitive to demethylation activity in cancer...
  54. ncbi request reprint Assignment of the developmentally regulated gene NEDD1 to human chromosome 12q22 by fluorescence in situ hybridization
    S Takai
    Department of Genetics, International Medical Center of Japan, Tokyo
    Hum Genet 95:96-8. 1995
    ..We have mapped the human homolog (NEDD1) of the mouse gene to chromosome 12q22 by fluorescence in situ hybridization using R-banded human (pro)metaphase chromosomes...
  55. ncbi request reprint Predictors of organ allograft tolerance following hematopoietic cell transplantation
    B M Horner
    Transplantation Biology Research Center, Harvard Medical School Massachusetts General Hospital, Boston, MA, USA
    Am J Transplant 6:2894-902. 2006
    ....
  56. ncbi request reprint Development of multidrug resistance type I Cmdr1 expression in chicken embryonic gonads
    K Yamada
    Laboratory of Reproductive Physiology and Biotechnology, Department of Animal and Marine Bioresource Sciences, Graduate School of Agriculture, Kyushu University, 6 10 1 Hakozaki, Fukuoka 812 8581, Japan
    Comp Biochem Physiol A Mol Integr Physiol 147:928-33. 2007
    ..Collectively, it is concluded that Cmdr1 expression is initiated in the chicken ovary and testis after sexual differentiation, but expression of Cmdr1-type P-gp is very low through embryogenesis...
  57. ncbi request reprint Assignment of the ect2 protooncogene to mouse chromosome band 3B by in situ hybridization
    S Takai
    Department of Genetics, Research Institute, International Medical Center of Japan, Tokyo Japan
    Cytogenet Cell Genet 81:83-4. 1998
  58. ncbi request reprint Localization of the gene (SLC1A3) encoding human glutamate transporter (GluT-1) to 5p13 by fluorescence in situ hybridization
    S Takai
    Department of Genetics, International Medical Center of Japan, Tokyo
    Cytogenet Cell Genet 69:209-10. 1995
    ..Chromosomal location of the human glutamate transporter, hGluT-1, gene (SLC1A3) was determined by fluorescence in situ hybridization. SLC1A3 was mapped to chromosome 5p13...
  59. pmc Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase)
    M Matsuki
    Department of Dermatology, Research Institute for Neurological Diseases and Geriatrics, Kyoto Prefectural University of Medicine, Kyoto 602, Japan
    Proc Natl Acad Sci U S A 95:1044-9. 1998
    ..Thus, these TGase 1 knockout mice may be a useful model for severe cases of LI...
  60. ncbi request reprint A comparative cytogenetic study of chromosome homology between chicken and Japanese quail
    M Shibusawa
    Laboratory of Cytogenetics, Division of Bioscience, Graduate School of Environmental Earth Science, Hokkaido University, Sapporo, Japan
    Cytogenet Cell Genet 95:103-9. 2001
    ....
  61. ncbi request reprint Schizosaccharomyces pombe homologue of glutathione peroxidase, which does not contain selenocysteine, is induced by several stresses and works as an antioxidant
    K Yamada
    Institute for Developmental Research, Aichi Human Service Center, 713 8 Kamiya cho, Kasugai, Aichi 480 0392, Japan
    Yeast 15:1125-32. 1999
    ..The catalase gene disruptant of S. pombe harbouring multicopy plasmid containing gpx1(+) restored the hypersensitivity to H(2)O(2) of the catalase gene disruptant. These results suggest that Gpx1 acts as a scavenger of H(2)O(2) in vivo...
  62. ncbi request reprint Chromosomal mapping of the gene encoding DOCK180, a major Crk-binding protein, to 10q26.13-q26.3 by fluorescence in situ hybridization
    S Takai
    Department of Genetics, Research Institute, International Medical Center of Japan, 1 21 1 Toyama, Shinjuku ku, Tokyo, 162, Japan
    Genomics 35:403-4. 1996
  63. ncbi request reprint Comparative FISH mapping of Gab1 and Gab2 genes in human, mouse and rat
    K Yamada
    Laboratory of Cytogenetics, Division of Bioscience, Graduate School of Environmental Earth Science, Sapporo, Japan
    Cytogenet Cell Genet 94:39-42. 2001
    ..4-->q13.5 in human, 7E2 in mouse and 1q33.2-->q33.3 in rat. All human, mouse and rat Gab1 and Gab2 genes were localized to chromosome regions where conserved homology has been identified among the three species...
  64. ncbi request reprint Cloning and characterization of gonadotropin-inducible ovarian transcription factors (GIOT1 and -2) that are novel members of the (Cys)(2)-(His)(2)-type zinc finger protein family
    T Mizutani
    Department of Biochemistry, Fukui Medical University, Matsuoka, Fukui 910 1193, Japan
    Mol Endocrinol 15:1693-705. 2001
    ....
  65. ncbi request reprint Association studies of the cholecystokinin B receptor and A2a adenosine receptor genes in panic disorder
    K Yamada
    Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Saitama, Japan
    J Neural Transm (Vienna) 108:837-48. 2001
    ..No evidence of association between the described variants and panic disorder was found. Our data therefore suggests that the CCKBR and A2aAR genes do not play major roles in the development of this disease...
  66. ncbi request reprint Human endothelin converting enzyme gene (ECE1) mapped to chromosomal region 1p36.1
    R Matsuoka
    Department of Pediatric Cardiology, The Heart Institute of Japan, Tokyo Women s Medical College, Japan
    Cytogenet Cell Genet 72:322-4. 1996
    ..Fluorescence in situ hybridization of a digoxigenin-labeled human ECE1 probe to normal human metaphase chromosomes showed that the gene is located within chromosome band 1p36.1...
  67. ncbi request reprint Tocopherol-associated protein is a ligand-dependent transcriptional activator
    J Yamauchi
    Division of Applied Food Research, National Institute of Health and Nutrition, 1 23 1 Toyama, Shinjyuku, Japan
    Biochem Biophys Res Commun 285:295-9. 2001
    ..These results suggest that the biological function of alpha-tocopherol is not only as an antioxidant but also as a transcriptional regulator of gene expression via association with a transcription factor TAP...
  68. ncbi request reprint Induction of transplantation tolerance with a short course of tacrolimus (FK506): I. Rapid and stable tolerance to two-haplotype fully mhc-mismatched kidney allografts in miniature swine
    R Utsugi
    Department of Pathology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts 02129, USA
    Transplantation 71:1368-79. 2001
    ..These studies may also have clinical applicability, because the time course required to induce tolerance was sufficiently short that the high drug levels required might be expected to be tolerated clinically with only transient toxicity...
  69. ncbi request reprint Role of Atf1 and Pap1 in the induction of the catalase gene of fission yeast schizosaccharomyces pombe
    C W Nakagawa
    Department of Genetics, Institute for Developmental Research, Kagiya cho, Kasugai, Aichi 480 0392, Japan aichi jp
    J Biochem 127:233-8. 2000
    ..The activity of catalase is not increased in pap1 cells by several stresses, despite mRNA induction, suggesting that Pap1 plays some role in the expression of catalase activity...
  70. ncbi request reprint An autosomal dominant posterior polar cataract locus maps to human chromosome 20p12-q12
    K Yamada
    Department of Human Genetics, Nagasaki University School of Medicine, Japan
    Eur J Hum Genet 8:535-9. 2000
    ..The mapping of the CPP3 locus to 20p12-q12 not only expands our understanding of the genetic heterogeneity in autosomal dominant posterior polar cataracts but also is a clue for the positional cloning of the disease gene...
  71. ncbi request reprint Possible involvement of EBV-mediated alpha-fodrin cleavage for organ-specific autoantigen in Sjogren's syndrome
    H Inoue
    Department of Pathology, Tokushima University School of Dentistry, Tokushima, Japan
    J Immunol 166:5801-9. 2001
    ..Thus, an increase in apoptotic protease activities induced by EBV reactivation may be involved in the progression of alpha-fodrin proteolysis in the development of SS...
  72. ncbi request reprint Gene cloning of immunogenic antigens overexpressed in pancreatic cancer
    T Nakatsura
    Division of Immunogenetics, Department of Neuroscience and Immunology, Kumamoto University Graduate School of Medical Sciences, 2 2 1 Honjo, Kumamoto, 860 0811, Japan
    Biochem Biophys Res Commun 281:936-44. 2001
    ..These molecules identified may provide good diagnostic markers for cancer cells...
  73. ncbi request reprint Isolation of a novel oncogene, NET1, from neuroepithelioma cells by expression cDNA cloning
    A M Chan
    Laboratory of Cellular and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Oncogene 12:1259-66. 1996
    ..The 3.0 and 2.4 kilobasepair (kb) transcripts of the NET1 gene was ubiquitously expressed in all tissues examined. Using fluorescence in situ hybridization, we localized the NET1 gene to the short arm of human chromosome 10 at band p15...