- Amla (Emblica officinalis Gaertn.) extract promotes procollagen production and inhibits matrix metalloproteinase-1 in human skin fibroblastsTakashi Fujii
Institute for Health Sciences, MIKI Corporation, 12 4, Naruohama 3, Nishinomiya 663 8142, Hyogo, Japan
J Ethnopharmacol 119:53-7. 2008..In this study, we investigated the effects of amla extract on human skin fibroblasts, especially for production of procollagen and matrix metalloproteinases (MMPs), in vitro...
- Prune extract (Prunus domestica L.) suppresses the proliferation and induces the apoptosis of human colon carcinoma Caco-2Takashi Fujii
Research and Development Institute, MIKI Corporation, 12 4, Naruohama 3, Nishinomiya, Hyogo 663 8142, Japan
J Nutr Sci Vitaminol (Tokyo) 52:389-91. 2006..Furthermore, by Caco-2 treatment with H2O2 chelator catalase and Ca2+-chelator BAPTA/AM, the PE-induced cytotoxic pathway was completely blocked, and the viable cell number of Caco-2 was not affected...
- Inhibitory effect of quercetin isolated from rose hip (Rosa canina L.) against melanogenesis by mouse melanoma cellsTakashi Fujii
Institute for Health Sciences, MIKI Corporation, 3 12 4 Naruohama, Nishinomiya, Hyogo 663 8142, Japan
Biosci Biotechnol Biochem 73:1989-93. 2009..We consider from these results that the inhibition of melanogenesis by quercetin was due to the inhibition of both tyrosinase activity and of the protein expression...
- Inhibitory effect of rose hip (Rosa canina L.) on melanogenesis in mouse melanoma cells and on pigmentation in brown guinea pigsTakashi Fujii
Institute for Health Sciences, MIKI Corporation, Nishinomiya, Hyogo, Japan
Biosci Biotechnol Biochem 75:489-95. 2011..These data collectively suggest that proanthocyanidins from RE inhibited melanogenesis in mouse melanoma cells and guinea pig skin, and could be useful as a skin-whitening agent when taken orally...