Shuji Noda

Summary

Affiliation: Chemicals Evaluation and Research Institute
Country: Japan

Publications

  1. ncbi request reprint Ability of the Hershberger assay protocol to detect thyroid function modulators
    Shuji Noda
    Chemicals Assessment Center, Chemicals Evaluation and Research Institute, 822, 3 Chome, Ishii machi, Hita shi, Oita 877 0061, Japan
    Arch Toxicol 79:627-35. 2005
  2. ncbi request reprint Preliminary evaluation of an in utero-lactation assay using 6-n-propyl-2-thiouracil
    Shuji Noda
    Chemicals Evaluation and Research Institute, 3 822 Ishii machi, Hita shi Oita, 877 0061, Japan
    Arch Toxicol 79:414-21. 2005
  3. ncbi request reprint Immature uterotrophic assay of estrogenic compounds in rats given diets of different phytoestrogen content and the ovarian changes with ICI 182,780 or antide
    Kanji Yamasaki
    Chemicals Assessment Center, Chemicals Evaluation and Research Institute, 3 822, Ishii, Hita, Oita 0877 0061, Japan
    Arch Toxicol 76:613-20. 2002
  4. ncbi request reprint In utero through lactational exposure to ethinyl estradiol induces cleft phallus and delayed ovarian dysfunction in the offspring
    Masakuni Sawaki
    Chemicals Evaluation and Research Institute, Chemicals Assessment Center, Hita, Oita, Japan
    Toxicol Sci 75:402-11. 2003
  5. ncbi request reprint Changes of serum alpha 2u-globulin in the subacute oral toxicity study of ethynyl estradiol and bisphenol A based on the draft protocol for the 'Enhanced OECD Test Guideline No. 407'
    Kanji Yamasaki
    Chemicals Evaluation and Research Institute, Chemicals Assessment Center, 3 822 Ishii, Hita, Oita 877 0061, Japan
    Toxicology 176:101-12. 2002
  6. ncbi request reprint Effects of in utero and lactational exposure to tamoxifen in SD rats
    Kanji Yamasaki
    Chemicals Evaluation and Research Institute, 3 822, Ishii, Hita, Oita 877 0061, Japan
    Toxicol Lett 156:289-96. 2005
  7. ncbi request reprint Advantage of using CBA/N strain mice in a non-radioisotopic modification of the local lymph node assay
    Masahiro Takeyoshi
    Hita Laboratory, Chemicals Evaluation and Research Institute, 3 822, Ishii machi, Hita shi, Oita 8770061, Japan
    J Appl Toxicol 26:5-9. 2006
  8. ncbi request reprint Effect of gonadotropin-releasing hormone antagonist on ovarian and uterine weights in immature female rats
    Masahiro Takeyoshi
    Chemicals Assessment Center, Chemicals Evaluation and Research Institute, 3 822 Ishii machi, Hita shi, Oita 8770061, Japan
    Reprod Toxicol 16:367-9. 2002
  9. ncbi request reprint Effects of in utero and lactational exposure to flutamide in SD rats: comparison of the effects of administration periods
    Kanji Yamasaki
    Chemicals Evaluation and Research Institute, 3 822, Ishii, Hita, Oita 877 0061, Japan
    Toxicology 209:47-54. 2005
  10. ncbi request reprint Evaluation of an in utero through lactational exposure protocol for detection of estrogenic effects of ethinyl estradiol on the offspring of rats: preliminary trial
    Masakuni Sawaki
    Chemicals Evaluation and Research Institute, 3 822, Ishii machi, Hita, Oita 877 0061, Japan
    Reprod Toxicol 17:335-43. 2003

Detail Information

Publications18

  1. ncbi request reprint Ability of the Hershberger assay protocol to detect thyroid function modulators
    Shuji Noda
    Chemicals Assessment Center, Chemicals Evaluation and Research Institute, 822, 3 Chome, Ishii machi, Hita shi, Oita 877 0061, Japan
    Arch Toxicol 79:627-35. 2005
    ..These results suggest that the effect of AT can be detected by the Hershberger assay 10-day administration protocol and may be useful for screening for thyroid function modulators regardless of whether the animals have been castrated...
  2. ncbi request reprint Preliminary evaluation of an in utero-lactation assay using 6-n-propyl-2-thiouracil
    Shuji Noda
    Chemicals Evaluation and Research Institute, 3 822 Ishii machi, Hita shi Oita, 877 0061, Japan
    Arch Toxicol 79:414-21. 2005
    ....
  3. ncbi request reprint Immature uterotrophic assay of estrogenic compounds in rats given diets of different phytoestrogen content and the ovarian changes with ICI 182,780 or antide
    Kanji Yamasaki
    Chemicals Assessment Center, Chemicals Evaluation and Research Institute, 3 822, Ishii, Hita, Oita 0877 0061, Japan
    Arch Toxicol 76:613-20. 2002
    ....
  4. ncbi request reprint In utero through lactational exposure to ethinyl estradiol induces cleft phallus and delayed ovarian dysfunction in the offspring
    Masakuni Sawaki
    Chemicals Evaluation and Research Institute, Chemicals Assessment Center, Hita, Oita, Japan
    Toxicol Sci 75:402-11. 2003
    ..These findings are consistent with delayed anovulation syndrome. The results suggest that observation of cyclicity at 6 months old is able to detect possible delayed ovarian dysfunction induced by perinatal exposure to chemicals...
  5. ncbi request reprint Changes of serum alpha 2u-globulin in the subacute oral toxicity study of ethynyl estradiol and bisphenol A based on the draft protocol for the 'Enhanced OECD Test Guideline No. 407'
    Kanji Yamasaki
    Chemicals Evaluation and Research Institute, Chemicals Assessment Center, 3 822 Ishii, Hita, Oita 877 0061, Japan
    Toxicology 176:101-12. 2002
    ..Although the alpha 2u-globulin level was reduced in this assay using BPA and EE, further studies are necessary before this assay becomes a useful method for detecting endocrine-mediated effects...
  6. ncbi request reprint Effects of in utero and lactational exposure to tamoxifen in SD rats
    Kanji Yamasaki
    Chemicals Evaluation and Research Institute, 3 822, Ishii, Hita, Oita 877 0061, Japan
    Toxicol Lett 156:289-96. 2005
    ..6 and 3 microg/kg/day groups. No abnormalities were detected in the reproductive performance of the male and female offspring...
  7. ncbi request reprint Advantage of using CBA/N strain mice in a non-radioisotopic modification of the local lymph node assay
    Masahiro Takeyoshi
    Hita Laboratory, Chemicals Evaluation and Research Institute, 3 822, Ishii machi, Hita shi, Oita 8770061, Japan
    J Appl Toxicol 26:5-9. 2006
    ....
  8. ncbi request reprint Effect of gonadotropin-releasing hormone antagonist on ovarian and uterine weights in immature female rats
    Masahiro Takeyoshi
    Chemicals Assessment Center, Chemicals Evaluation and Research Institute, 3 822 Ishii machi, Hita shi, Oita 8770061, Japan
    Reprod Toxicol 16:367-9. 2002
    ....
  9. ncbi request reprint Effects of in utero and lactational exposure to flutamide in SD rats: comparison of the effects of administration periods
    Kanji Yamasaki
    Chemicals Evaluation and Research Institute, 3 822, Ishii, Hita, Oita 877 0061, Japan
    Toxicology 209:47-54. 2005
    ..The present data demonstrated that the endocrine-mediated effects on rats were more appreciable in offspring treated with FLUT after weaning than in offspring untreated after weaning...
  10. ncbi request reprint Evaluation of an in utero through lactational exposure protocol for detection of estrogenic effects of ethinyl estradiol on the offspring of rats: preliminary trial
    Masakuni Sawaki
    Chemicals Evaluation and Research Institute, 3 822, Ishii machi, Hita, Oita 877 0061, Japan
    Reprod Toxicol 17:335-43. 2003
    ....
  11. ncbi request reprint Comparison of toxicity studies based on the draft protocol for the 'Enhanced OECD Test Guideline no. 407' and the research protocol of 'Pubertal Development and Thyroid Function in Immature Male Rats' with 6-n-propyl-2-thiouracil
    Kanji Yamasaki
    Chemicals Assessment Center, Chemicals Evaluation and Research Institute, 3 822, Ishii, Hita, Oita 877 0061, Japan
    Arch Toxicol 76:495-501. 2002
    ....
  12. ncbi request reprint Comparative study of the uterotrophic potency of 14 chemicals in a uterotrophic assay and their receptor-binding affinity
    Kanji Yamasaki
    Chemicals Assessment Center, Chemicals Evaluation and Research Institute, 3 822 Ishii, Hita, 877 0061 Oita, Japan
    Toxicol Lett 146:111-20. 2004
    ....
  13. ncbi request reprint Uterotrophic and Hershberger assays for n-butylbenzene in rats
    Kanji Yamasaki
    Chemicals Assessment Center, Chemicals Evaluation and Research Institute, Hita, Oita, Japan
    Arch Toxicol 75:703-6. 2002
    ..These findings suggest that nBB does not have any endocrine-disrupting properties on in vivo screening tests...
  14. ncbi request reprint Subacute oral toxicity study of ethynylestradiol and bisphenol A, based on the draft protocol for the "Enhanced OECD Test Guideline no. 407"
    Kanji Yamasaki
    Chemicals Assessment Center, Chemicals Evaluation and Research Institute, 3 822 Ishii, Hita, Oita 877 0061, Japan
    Arch Toxicol 76:65-74. 2002
    ....
  15. ncbi request reprint Differences in responsiveness of mouse strain against p-benzoquinone as assessed by non-radioisotopic murine local lymph node assay
    Masahiro Takeyoshi
    Hita Laboratory, Chemicals Evaluation and Research Institute, Japan, Oita, Japan
    Exp Anim 53:171-3. 2004
    ..These results support the recommendation in the OECD test guideline 429 and the skin sensitization test guideline of US-EPA with regard to the selection of mouse strain for LLNA...
  16. ncbi request reprint Age-related changes of genital systems in the female Crj:CD (SD) IGS rats during sexual maturation
    Shuji Noda
    Chemicals Assessment Center, Chemicals Evaluation and Research Institute, Oita, Japan
    J Vet Med Sci 64:315-9. 2002
    ..In addition, it is assumed that the first ovulation precedes or occurs simultaneously with vaginal opening...
  17. ncbi request reprint The efficacy of endocrine disruptor screening tests in detecting anti-estrogenic effects downstream of receptor-ligand interactions
    Masahiro Takeyoshi
    Chemicals Assessment Center, Chemicals Evaluation and Research Institute, 3 822, Ishii machi, Hita shi, 8770061, Oita, Japan
    Toxicol Lett 126:91-8. 2002
    ..Particularly, the reporter gene assay may be a promising prescreening procedure, because it can be adopted in the high throughput screening process for thousands of chemicals and it requires no use of experimental animals...
  18. ncbi request reprint Assessment of the skin sensitization potency of eugenol and its dimers using a non-radioisotopic modification of the local lymph node assay
    Masahiro Takeyoshi
    Chemicals Assessment Center, Chemicals Evaluation and Research Institute, 3 822, Ishii machi, Hita shi, Oita 8770061, Japan
    J Appl Toxicol 24:77-81. 2004
    ..These investigations provide support for the proposal that the non-radioisotopic LLNA may serve as an effective alternative to the GPMT where there is a need to avoid the use of radioisotopes...