K Mineura

Summary

Affiliation: Akita University School of Medicine
Country: Japan

Publications

  1. ncbi request reprint Early delineation of cerebral glioma using amino acid positron tracers
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    Comput Med Imaging Graph 21:63-6. 1997
  2. ncbi request reprint Enhancement effect of O6-fluorobenzylguanines on chloroethylnitrosourea cytotoxicity in tumor cells
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    Life Sci 58:PL303-8. 1996
  3. ncbi request reprint Human brain tumor O(6)-methylguanine-DNA methyltransferase mRNA and its significance as an indicator of selective chloroethylnitrosourea chemotherapy
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    Int J Cancer 69:420-5. 1996
  4. ncbi request reprint Tumor extent of slowly progressive oligodendroglioma determined by 18F-fluorophenylalanine positron emission tomography
    K Mineura
    Neurosurgical Service, Akita University, Japan
    Eur J Radiol 25:30-5. 1997
  5. ncbi request reprint Blood flow and metabolism of oligodendrogliomas: a positron emission tomography study with kinetic analysis of 18F-fluorodeoxyglucose
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    J Neurooncol 43:49-57. 1999
  6. ncbi request reprint Brain tumor imaging with synthesized 18F-fluorophenylalanine and positron emission tomography
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    Surg Neurol 31:468-9. 1989
  7. ncbi request reprint O6-methylguanine-DNA methyltransferase activity in cerebral gliomas. A guidance for nitrosourea treatment?
    K Mineura
    Neurological Service, Akita University Hospital, Japan
    Acta Oncol 33:29-32. 1994
  8. ncbi request reprint Subependymoma of the septum pellucidum: characterization by PET
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    J Neurooncol 32:143-7. 1997
  9. ncbi request reprint O6-(fluorobenzyl)guanine and chloroethylnitrosourea in xenografted rat brain tumor in vivo
    M Takahashi
    Neurosurgical Service, Akita University Hospital, Japan
    Acta Oncol 39:89-95. 2000
  10. ncbi request reprint Development of resistance to antitumor chloroethylnitrosoureas in vitro in brain tumor cells
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    Acta Oncol 31:755-9. 1992

Detail Information

Publications10

  1. ncbi request reprint Early delineation of cerebral glioma using amino acid positron tracers
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    Comput Med Imaging Graph 21:63-6. 1997
    ..Five years and one month after, an enhancing mass appeared on CT scans. Thus, amino acid tracers may play a important role in the early diagnosis of gliomas...
  2. ncbi request reprint Enhancement effect of O6-fluorobenzylguanines on chloroethylnitrosourea cytotoxicity in tumor cells
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    Life Sci 58:PL303-8. 1996
    ..The chemical features of the O6-benzyl group are a biologically important determinant in the reaction evolution with MGMT...
  3. ncbi request reprint Human brain tumor O(6)-methylguanine-DNA methyltransferase mRNA and its significance as an indicator of selective chloroethylnitrosourea chemotherapy
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    Int J Cancer 69:420-5. 1996
    ..05 determined by Gehan's Wilcoxon test). These results indicate that a fraction of brain tumors have a low expression of MGMT mRNA, and that the level of MGMT mRNA is a useful indicator of effectiveness in selective CENU chemotherapy...
  4. ncbi request reprint Tumor extent of slowly progressive oligodendroglioma determined by 18F-fluorophenylalanine positron emission tomography
    K Mineura
    Neurosurgical Service, Akita University, Japan
    Eur J Radiol 25:30-5. 1997
    ..The accuracy of the 18F-Phe PET technique for determining the extent of a tumor is valuable and will aid in the selection of an appropriate therapy modality for the management of oligodendrogliomas...
  5. ncbi request reprint Blood flow and metabolism of oligodendrogliomas: a positron emission tomography study with kinetic analysis of 18F-fluorodeoxyglucose
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    J Neurooncol 43:49-57. 1999
    ..Circulation and metabolism measured by PET provide in vivo biological characteristics, including proliferating activity, in oligodendrogliomas...
  6. ncbi request reprint Brain tumor imaging with synthesized 18F-fluorophenylalanine and positron emission tomography
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    Surg Neurol 31:468-9. 1989
    ..The tracer accumulated markedly in the tumor lesion and delineated the extent of the lesion. This new tracer will be promising in the diagnosis of gliomas...
  7. ncbi request reprint O6-methylguanine-DNA methyltransferase activity in cerebral gliomas. A guidance for nitrosourea treatment?
    K Mineura
    Neurological Service, Akita University Hospital, Japan
    Acta Oncol 33:29-32. 1994
    ..The activity of brain tissue, available from the peritumoral region of five cases, varied between 38 to 415 fmol/mg. Four of the five regions showed a higher value than the respective tumor, and one showed a lower value...
  8. ncbi request reprint Subependymoma of the septum pellucidum: characterization by PET
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    J Neurooncol 32:143-7. 1997
    ..The tumor showed exceedingly low rates of glucose metabolism (rCMRG1) and kinetic constants (K1, K2, and K3). This hypometabolism indicates low cellular density and slow growth...
  9. ncbi request reprint O6-(fluorobenzyl)guanine and chloroethylnitrosourea in xenografted rat brain tumor in vivo
    M Takahashi
    Neurosurgical Service, Akita University Hospital, Japan
    Acta Oncol 39:89-95. 2000
    ..In contrast, 2F did not enhance the ACNU anti-tumor effect. These results indicate that O6-(4- and 3-fluorobenzyl)guanines as well as O6-benzylguanines enhance the effect of ACNU on the growth of C6 tumor xenografts in vivo...
  10. ncbi request reprint Development of resistance to antitumor chloroethylnitrosoureas in vitro in brain tumor cells
    K Mineura
    Neurosurgical Service, Akita University Hospital, Japan
    Acta Oncol 31:755-9. 1992
    ..The easily obtained acquired resistance to CENUs suggests a clinical disadvantage of continual and repeated adjuvant monochemotherapy with these agents...