Sonia Scarfi

Summary

Affiliation: University of Genoa
Country: Italy

Publications

  1. ncbi request reprint Ascorbic acid-pretreated quartz enhances cyclo-oxygenase-2 expression in RAW 264.7 murine macrophages
    Sonia Scarfi
    Advanced Biotechnology Center, Genoa, Italy
    FEBS J 274:60-73. 2007
  2. doi request reprint Cyclic ADP-ribose-mediated expansion and stimulation of human mesenchymal stem cells by the plant hormone abscisic acid
    Sonia Scarfi
    Department of Experimental Medicine, Section of Biochemistry, Advanced Biotechnology Center, University of Genova, Genova, Italy
    Stem Cells 26:2855-64. 2008
  3. pmc Ascorbic acid pre-treated quartz stimulates TNF-alpha release in RAW 264.7 murine macrophages through ROS production and membrane lipid peroxidation
    Sonia Scarfi
    Department of Experimental Medicine, Section of Biochemistry, University of Genova, Genova, Italy
    Respir Res 10:25. 2009
  4. doi request reprint Autocrine abscisic acid plays a key role in quartz-induced macrophage activation
    Mirko Magnone
    DIMES, Section of Biochemistry, University of Genova, Viale Benedetto XV, 1 16132 Genova, Italy
    FASEB J 26:1261-71. 2012
  5. doi request reprint The plant hormone abscisic acid stimulates the proliferation of human hemopoietic progenitors through the second messenger cyclic ADP-ribose
    Sonia Scarfi
    Advanced Biotechnology Center, Genova, Italy
    Stem Cells 27:2469-77. 2009
  6. pmc LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells
    Laura Sturla
    Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV 1, Genova 16132, Italy
    J Biol Chem 284:28045-57. 2009
  7. pmc Abscisic acid released by human monocytes activates monocytes and vascular smooth muscle cell responses involved in atherogenesis
    Mirko Magnone
    Department of Experimental Medicine, Section of Biochemistry and Center of Excellence for Biomedical Research, University of Genova, and Vascular and Endovascular Surgery Unit, San Martino Hospital, Viale Benedetto XV 1, 16132 Genova, Italy
    J Biol Chem 284:17808-18. 2009
  8. doi request reprint Fluridone as a new anti-inflammatory drug
    Mirko Magnone
    Department of Experimental Medicine, University of Genova, Viale Benedetto XV 1, 16132 Genova, Italy Electronic address
    Eur J Pharmacol 720:7-15. 2013
  9. pmc Abscisic acid activates the murine microglial cell line N9 through the second messenger cyclic ADP-ribose
    Nicoletta Bodrato
    Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV 1, 16132 Genova, Italy
    J Biol Chem 284:14777-87. 2009
  10. doi request reprint Regulation of human mesenchymal stem cell functions by an autocrine loop involving NAD+ release and P2Y11-mediated signaling
    Floriana Fruscione
    Advanced Biotechnology Center, Genova, Italy
    Stem Cells Dev 20:1183-98. 2011

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Ascorbic acid-pretreated quartz enhances cyclo-oxygenase-2 expression in RAW 264.7 murine macrophages
    Sonia Scarfi
    Advanced Biotechnology Center, Genoa, Italy
    FEBS J 274:60-73. 2007
    ....
  2. doi request reprint Cyclic ADP-ribose-mediated expansion and stimulation of human mesenchymal stem cells by the plant hormone abscisic acid
    Sonia Scarfi
    Department of Experimental Medicine, Section of Biochemistry, Advanced Biotechnology Center, University of Genova, Genova, Italy
    Stem Cells 26:2855-64. 2008
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  3. pmc Ascorbic acid pre-treated quartz stimulates TNF-alpha release in RAW 264.7 murine macrophages through ROS production and membrane lipid peroxidation
    Sonia Scarfi
    Department of Experimental Medicine, Section of Biochemistry, University of Genova, Genova, Italy
    Respir Res 10:25. 2009
    ..7...
  4. doi request reprint Autocrine abscisic acid plays a key role in quartz-induced macrophage activation
    Mirko Magnone
    DIMES, Section of Biochemistry, University of Genova, Viale Benedetto XV, 1 16132 Genova, Italy
    FASEB J 26:1261-71. 2012
    ..AMs showed similar early and late ABA-induced responses as RAW264.7 cells. These findings identify ABA and LANCL2 as key mediators in quartz-induced inflammation, providing possible new targets for antisilicotic therapy...
  5. doi request reprint The plant hormone abscisic acid stimulates the proliferation of human hemopoietic progenitors through the second messenger cyclic ADP-ribose
    Sonia Scarfi
    Advanced Biotechnology Center, Genova, Italy
    Stem Cells 27:2469-77. 2009
    ..These results provide a remarkable example of conservation of a stress hormone and of its second messenger from plants to humans and identify ABA as a new hemopoietic growth factor involved in the cross-talk between HP and MSC...
  6. pmc LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells
    Laura Sturla
    Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV 1, Genova 16132, Italy
    J Biol Chem 284:28045-57. 2009
    ..Identification of LANCL2 as a critical component of the ABA-sensing protein complex will enable the screening of synthetic ABA antagonists as prospective new anti-inflammatory and anti-diabetic agents...
  7. pmc Abscisic acid released by human monocytes activates monocytes and vascular smooth muscle cell responses involved in atherogenesis
    Mirko Magnone
    Department of Experimental Medicine, Section of Biochemistry and Center of Excellence for Biomedical Research, University of Genova, and Vascular and Endovascular Surgery Unit, San Martino Hospital, Viale Benedetto XV 1, 16132 Genova, Italy
    J Biol Chem 284:17808-18. 2009
    ....
  8. doi request reprint Fluridone as a new anti-inflammatory drug
    Mirko Magnone
    Department of Experimental Medicine, University of Genova, Viale Benedetto XV 1, 16132 Genova, Italy Electronic address
    Eur J Pharmacol 720:7-15. 2013
    ..These results suggest that Fluridone could represent a new prototype of anti-inflammatory drug, also active on abscisic acid pro-inflammatory pathway. ..
  9. pmc Abscisic acid activates the murine microglial cell line N9 through the second messenger cyclic ADP-ribose
    Nicoletta Bodrato
    Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV 1, 16132 Genova, Italy
    J Biol Chem 284:14777-87. 2009
    ....
  10. doi request reprint Regulation of human mesenchymal stem cell functions by an autocrine loop involving NAD+ release and P2Y11-mediated signaling
    Floriana Fruscione
    Advanced Biotechnology Center, Genova, Italy
    Stem Cells Dev 20:1183-98. 2011
    ..These findings suggest a potential beneficial role of NAD(+)(e) in modulating MSC functions relevant to MSC-based cell therapies...
  11. pmc Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger
    Santina Bruzzone
    Department of Experimental Medicine, Section of Biochemistry, University of Genova, Viale Benedetto XV 1, 16132 Genoa, Italy
    Proc Natl Acad Sci U S A 104:5759-64. 2007
    ....
  12. doi request reprint Abscisic acid is an endogenous stimulator of insulin release from human pancreatic islets with cyclic ADP ribose as second messenger
    Santina Bruzzone
    Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV 1, 16132 Genova, Italy
    J Biol Chem 283:32188-97. 2008
    ....
  13. ncbi request reprint Selective inhibition of inducible cyclo-oxygenase-2 expression by antisense peptide nucleic acids in intact murine macrophages
    Sonia Scarfi
    Department of Experimental Medicine, Biochemistry Section, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy
    Biotechnol Appl Biochem 38:61-9. 2003
    ....
  14. doi request reprint The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts
    Santina Bruzzone
    Department of Experimental Medicine, University of Genova, Viale Benedetto XV, 1 16132 Genova, Italy
    FASEB J 26:1251-60. 2012
    ....
  15. doi request reprint Pichia pastoris production of a prolyl 4-hydroxylase derived from Chondrosia reniformis sponge: A new biotechnological tool for the recombinant production of marine collagen
    Marina Pozzolini
    Department of Earth, Environment and Life Sciences, University of Genova, Via Pastore 3, 16132, Genova, Italy
    J Biotechnol 208:28-36. 2015
    ....
  16. ncbi request reprint Induction by 7,12-dimethylbenz(a)anthracene of molecular and biochemical alterations in transformed human mammary epithelial stem cells, and protection by N-acetylcysteine
    Silvio De Flora
    Department of Health Sciences, Section of Hygiene and Preventive Medicine, University of Genoa, I 16132 Genoa, Italy
    Int J Oncol 29:521-9. 2006
    ..Thus, the immortal cell line derived from the normal human adult breast stem cell without further tumorigenic progression is the most susceptible both to DMBA-related alterations and to the protective effects of NAC...
  17. doi request reprint Effects on Energy Metabolism of Two Guanidine Molecules, (Boc)2 -Creatine and Metformin
    Patrizia Garbati
    Department of Neuroscience, Ophthalmology, Genetics, Maternal Infantile Sciences, University of Genova, Largo Paolo Daneo 3, 16132, Genova, Italy
    J Cell Biochem . 2017
    ..Further research is needed to understand what types of cancer cells are most suitable to treatment by this new compound. This article is protected by copyright. All rights reserved...
  18. doi request reprint Molecular Cloning, Characterization, and Expression Analysis of a Prolyl 4-Hydroxylase from the Marine Sponge Chondrosia reniformis
    Marina Pozzolini
    Department of Territory Environment and Life Sciences, University of Genova, Via Pastore 3, 16132, Genova, Italy
    Mar Biotechnol (NY) 17:393-407. 2015
    ....
  19. doi request reprint Different reactivity of primary fibroblasts and endothelial cells towards crystalline silica: A surface radical matter
    Marina Pozzolini
    Department of Earth, Environment and Life Sciences, University of Genova, Via Pastore 3, 16132 Genova, Italy
    Toxicology 361:12-23. 2016
    ..In conclusion, our in vitro experimental model demonstrates an important and quite unexplored direct contribute of silica surface radicals to fibroblast proliferation and fibrogenic responses. ..
  20. doi request reprint Cell reactivity to different silica
    Marco Giovine
    Dipartimento di Scienze della Terra, dell Ambiente e della Vita, University of Genova, Genoa, Italy
    Prog Mol Subcell Biol 54:143-74. 2013
    ..The presence of silica in sea water and substrates also affects processes like the settlement of larvae and the growth of diatoms. The following sections review all such aspects. ..
  21. pmc Hyccin, the molecule mutated in the leukodystrophy hypomyelination and congenital cataract (HCC), is a neuronal protein
    Elisabetta Gazzerro
    Muscular and Neurodegenerative Disease Unit, G Gaslini Institute, University of Genoa, Genoa, Italy
    PLoS ONE 7:e32180. 2012
    ..As Hyccin is primarily expressed in neurons and its mutation leads to hypomyelination in human patients, we suggest that the protein is involved in neuron-to-glia signalling to initiate or maintain myelination...