Leonardo Punzi

Summary

Affiliation: University of Padova
Country: Italy

Publications

  1. ncbi Erosive osteoarthritis
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova Policlinico Universitario, Via Giustiniani 2, 35128 Padova, Italy
    Best Pract Res Clin Rheumatol 18:739-58. 2004
  2. ncbi Mud-bath treatment in spondylitis associated with inflammatory bowel disease--a pilot randomised clinical trial
    Franco Cozzi
    Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Joint Bone Spine 74:436-9. 2007
  3. doi Methods used to assess remission and low disease activity in rheumatoid arthritis
    Francesca Ometto
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, 35128 Padova, Italy
    Autoimmun Rev 9:161-4. 2010
  4. pmc Epigallocatechin-3-gallate reduces inflammation induced by calcium pyrophosphate crystals in vitro
    Francesca Oliviero
    Rheumatology Unit, Department of Medicine, University of Padova Padova, Italy
    Front Pharmacol 4:51. 2013
  5. doi Efficacy and safety of certolizumab pegol in rheumatoid arthritis: meeting rheumatologists' requirements in routine clinical practice
    Leonardo Punzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, 35128, Padua, Italy
    BioDrugs 28:S25-37. 2014
  6. doi Serum uric acid and gout: from the past to molecular biology
    L Punzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padua, Italy
    Curr Med Res Opin 29:3-8. 2013
  7. doi Gout as autoinflammatory disease: new mechanisms for more appropriated treatment targets
    Leonardo Punzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Italy
    Autoimmun Rev 12:66-71. 2012
  8. doi Coll2-1, Coll2-1NO2 and myeloperoxidase serum levels in erosive and non-erosive osteoarthritis of the hands
    L Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Italy
    Osteoarthritis Cartilage 20:557-61. 2012
  9. doi Psoriatic arthritis. When the heterogeneity requires normality
    L Punzi
    University of Padova
    Reumatismo 64:59-65. 2012
  10. doi Miscellaneous non-inflammatory musculoskeletal conditions. Blau syndrome
    Leonardo Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padua, Italy
    Best Pract Res Clin Rheumatol 25:703-14. 2011

Detail Information

Publications152 found, 100 shown here

  1. ncbi Erosive osteoarthritis
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova Policlinico Universitario, Via Giustiniani 2, 35128 Padova, Italy
    Best Pract Res Clin Rheumatol 18:739-58. 2004
    ..No definitive therapeutic approach to EOA has been reported. It is reasonable to assume that in the presence of a symptomatic EOA our therapeutic approach should differ from that used for common, nodal, non-EOA...
  2. ncbi Mud-bath treatment in spondylitis associated with inflammatory bowel disease--a pilot randomised clinical trial
    Franco Cozzi
    Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Joint Bone Spine 74:436-9. 2007
    ..The objective of this study was to evaluate the effects and the tolerability of mud packs and thermal baths in a group of patients affected with this disease...
  3. doi Methods used to assess remission and low disease activity in rheumatoid arthritis
    Francesca Ometto
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, 35128 Padova, Italy
    Autoimmun Rev 9:161-4. 2010
    ..Thus, those reported by FDA are the only criteria for remission which consider radiographic arrest of the disease. This review aims to describe the criteria for RA remission and to discuss their advantages and limitations...
  4. pmc Epigallocatechin-3-gallate reduces inflammation induced by calcium pyrophosphate crystals in vitro
    Francesca Oliviero
    Rheumatology Unit, Department of Medicine, University of Padova Padova, Italy
    Front Pharmacol 4:51. 2013
    ....
  5. doi Efficacy and safety of certolizumab pegol in rheumatoid arthritis: meeting rheumatologists' requirements in routine clinical practice
    Leonardo Punzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, 35128, Padua, Italy
    BioDrugs 28:S25-37. 2014
    ..Current data suggest that certolizumab pegol suits a 'treat to target' approach, providing rapid and sustained improvements in RA signs and symptoms, and beneficial effects on workplace and home productivity in patients with RA...
  6. doi Serum uric acid and gout: from the past to molecular biology
    L Punzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padua, Italy
    Curr Med Res Opin 29:3-8. 2013
    ..This review will briefly present the epidemiology and risk factors of gout, with a focus on recent advances...
  7. doi Gout as autoinflammatory disease: new mechanisms for more appropriated treatment targets
    Leonardo Punzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Italy
    Autoimmun Rev 12:66-71. 2012
    ..All these aspects, leading to deeper insight, have suggested new treatments, some of which are already available while others are likely to become available in the near future...
  8. doi Coll2-1, Coll2-1NO2 and myeloperoxidase serum levels in erosive and non-erosive osteoarthritis of the hands
    L Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Italy
    Osteoarthritis Cartilage 20:557-61. 2012
    ....
  9. doi Psoriatic arthritis. When the heterogeneity requires normality
    L Punzi
    University of Padova
    Reumatismo 64:59-65. 2012
    ..This seems obtained with a convenient cost-effectiveness ratio...
  10. doi Miscellaneous non-inflammatory musculoskeletal conditions. Blau syndrome
    Leonardo Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padua, Italy
    Best Pract Res Clin Rheumatol 25:703-14. 2011
    ..This review will focus on the clinical and genetics aspects of the familial and the sporadic form of BS. Further, we will describe an Italian family followed by us over the past 25 years...
  11. doi Metabolism of crystals within the joint
    F Oliviero
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Reumatismo 63:221-9. 2011
    ..We review how MSU and calcium crystals form within the joints and the various factor which regulate their formation...
  12. ncbi Clinical significance of cytokine determination in synovial fluid
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Italy
    Crit Rev Clin Lab Sci 39:63-88. 2002
    ..Furthermore, as some of these cytokines may reflect disease activity, their determination may also be useful in the evaluation of therapy...
  13. ncbi Clinical manifestations and outcome of polyarthralgia associated with chronic lymphocytic thyroiditis
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Semin Arthritis Rheum 32:51-5. 2002
    ..Our study aims to characterize arthralgia and, in particular, polyarthralgia (PA) associated with CLT and to evaluate the influence of thyroid replacement therapy...
  14. pmc Serum human cartilage glycoprotein 39 as a marker of arthritis associated with inflammatory bowel disease
    L Punzi
    Division of Rheumatology, University of Padova, Italy
    Ann Rheum Dis 62:1224-6. 2003
    ..Common blood markers of arthritis are difficult to interpret in arthritis associated with inflammatory bowel disease (IBD) owing to the coexistence of two inflammatory events. No specific serological disease marker is available for IBD...
  15. ncbi Laboratory investigations in osteoarthritis
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Aging Clin Exp Res 15:373-9. 2003
    ....
  16. ncbi Chronic autoimmune thyroiditis and rheumatic manifestations
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Via Giustiniani 2, Padova 35128, Italy
    Joint Bone Spine 71:275-83. 2004
    ....
  17. ncbi [Italian consensus on Eular 2003 recommendations for the treatment of knee osteoarthritis]
    L Punzi
    Cattedra ed UOC di Reumatologia, Universita di Padova, Padova
    Reumatismo 56:190-201. 2004
    ..Furthermore, the final document of the Italian Consensus clearly indicated the need that specialists involved in the management of knee OA strongly encourage the dissemination of the EULAR 2003 recommendations also in Italy...
  18. pmc Value of C reactive protein in the assessment of erosive osteoarthritis of the hand
    L Punzi
    Cattedra e Divisione di Reumatologia, Universita di Padova, Via Giustiniani, 235128 Padua, Italy
    Ann Rheum Dis 64:955-7. 2005
    ..To investigate the value of serum C reactive protein (CRP) as a marker of erosive osteoarthritis (EOA) of the hand...
  19. ncbi Laboratory findings in osteoarthritis
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Semin Arthritis Rheum 34:58-61. 2005
  20. ncbi New biochemical insights into the pathogenesis of osteoarthritis and the role of laboratory investigations in clinical assessment
    Leonardo Punzi
    Division of Rheumatology, University of Padova, Italy
    Crit Rev Clin Lab Sci 42:279-309. 2005
    ....
  21. ncbi [Italian consensus on EULAR recommendations 2005 for the management of hip osteoarthritis]
    L Punzi
    Cattedra ed Unità Operativa di Reumatologia, Universita di Padova, Italia
    Reumatismo 58:301-9. 2006
    ..Furthermore, the final document of the Italian Consensus clearly indicated the need that the specialists involved in the management of hip OA strongly encourage the dissemination of the EULAR 2005 recommendations also in Italy...
  22. ncbi Laboratory findings in psoriatic arthritis
    L Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Italy
    Reumatismo 59:52-5. 2007
    ....
  23. ncbi Pathogenetic and clinical rationale for TNF-blocking therapy in psoriatic arthritis
    Leonardo Punzi
    Rheumatology Unit, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Autoimmun Rev 6:524-8. 2007
    ..In this new fashion, the most stimulating hypotheses involving TNF are those regarding genetic predisposition, angiogenesis and osteoclastogenesis...
  24. ncbi [Italian Society of Rheumatology (SIR) recommendations for performing arthrocentesis]
    L Punzi
    Cattedra ed UOC Reumatologia, Universita di Padova, Italia
    Reumatismo 59:227-34. 2007
    ..Several of these recommendations were based on experts' opinion rather than on published evidence which is scanty...
  25. doi Clinical and genetic aspects of Blau syndrome: a 25-year follow-up of one family and a literature review
    Leonardo Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Italy
    Autoimmun Rev 8:228-32. 2009
    ..As in Crohn's disease, CARD15/NOD2 mutation is believed to be responsible for the granulomatous autoinflammatory reactions probably triggered by microorganisms in BS...
  26. doi Arthrocentesis and synovial fluid analysis in clinical practice: value of sonography in difficult cases
    Leonardo Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padua, Italy
    Ann N Y Acad Sci 1154:152-8. 2009
    ..Furthermore, ultrasonography may be useful in revealing the presence of synovial fluid before the joint aspiration and, subsequently, distinguishing some aspects characteristic of crystal-induced arthropathies...
  27. doi New horizons in osteoarthritis
    F Oliviero
    Department of Clinical and Experimental Rheumatology, University of Padova, Via Giustiniani, Padova, IT
    Swiss Med Wkly 140:w13098. 2010
    ..Numerous new substances have been formulated and the findings of trials studying their effects are encouraging, although much has yet to be done...
  28. doi Inflammatory osteoarthritis of the hand
    Leonardo Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Best Pract Res Clin Rheumatol 24:301-12. 2010
    ..Thus, it is probably preferable to use the double term inflammatory/erosive to better define this particular subset of HOA...
  29. doi The prevalence of monosodium urate and calcium pyrophosphate crystals in synovial fluid from wrist and finger joints
    Paola Galozzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy
    Rheumatol Int 36:443-6. 2016
    ..The finding underlines the importance of analyzing SF from the hand and wrist joints in the attempt to identify comorbidities associated with the presence of crystals and to develop targeted treatment strategies...
  30. doi Blockade of intra-articular TNF in peripheral spondyloarthritis: its relevance to clinical scores, quantitative imaging and synovial fluid and synovial tissue biomarkers
    Ugo Fiocco
    Department of Medicine, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
    Joint Bone Spine 80:165-70. 2013
    ....
  31. doi Prevalence of calcium pyrophosphate and monosodium urate crystals in synovial fluid of patients with previously diagnosed joint diseases
    Francesca Oliviero
    Rheumatology Unit, Department of Medicine, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
    Joint Bone Spine 80:287-90. 2013
    ..The main aim of this study was to investigate the frequency of monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals in synovial fluid (SF) obtained from patients with previously diagnosed joint diseases...
  32. doi The effects of combined spa therapy and rehabilitation on patients with ankylosing spondylitis being treated with TNF inhibitors
    Luca Ciprian
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Rheumatol Int 33:241-5. 2013
    ..Combined spa therapy and rehabilitation caused a clear, long-term clinical improvement in AS patients being treated with TNF inhibitors. Thermal treatment was found to be well tolerated and none of the patients had disease relapse...
  33. ncbi Disease activity patterns in a monocentric cohort of SLE patients: a seven-year follow-up study
    Margherita Zen
    Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Italy
    Clin Exp Rheumatol 30:856-63. 2012
    ..To evaluate disease activity patterns and flare occurrence in a cohort of systemic lupus erythematosus (SLE) patients...
  34. doi Synovial biomarkers in psoriatic arthritis
    Ugo Fiocco
    Department of Medicine, University of Padua, Padua, Italy
    J Rheumatol Suppl 89:61-4. 2012
    ..5 mg)...
  35. doi Elderly onset of primary Sjögren's syndrome: clinical manifestations, serological features and oral/ocular diagnostic tests. Comparison with adult and young onset of the disease in a cohort of 336 Italian patients
    Costantino Botsios
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Joint Bone Spine 78:171-4. 2011
    ..To study and compare the clinical and serological features of patients with elderly versus adult and younger onset of primary Sjögren's syndrome (pSS)...
  36. doi Cytokine levels in human synovial fluid during the different stages of acute gout: role of transforming growth factor β1 in the resolution phase
    Anna Scanu
    Rheumatology Unit, Department of Medicine, University of Padova, Italy
    Ann Rheum Dis 71:621-4. 2012
    ..To determine the most relevant parameters in synovial fluid (SF) during the various stages of acute gout...
  37. doi Plasma-exchange as a "rescue therapy" for dermato/polymyositis in acute phase. Experience in three young patients
    Franco Cozzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Italy Electronic address
    Transfus Apher Sci 53:368-72. 2015
    ..The tracheostomy and PEG tubes could be removed. Our findings suggest that plasma-exchange in association with immunosuppressant agents could play a relevant role in the management of dermato/polymyositis in acute phase. ..
  38. doi Rituximab in refractory idiopathic inflammatory myopathies and antisynthetase syndrome: personal experience and review of the literature
    Linda Nalotto
    Division of Rheumatology, Department of Medicine, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy
    Immunol Res 56:362-70. 2013
    ..A significant improvement was observed in 80% of patients overall and the drug was well tolerated in the majority of cases. In conclusion, RTX can be considered a therapeutic option in refractory IIM...
  39. doi Serological markers in psoriatic arthritis: promising tools
    Roberta Ramonda
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, 35128 Padova, Italy
    Exp Biol Med (Maywood) 238:1431-6. 2013
    ..The rise in PTX3 did not appear to be linked to the inflammatory state of the disease but might be an expression of the atherosclerotic process frequently observed in PsA. ..
  40. doi Treatment of 139 pregnancies in antiphospholipid-positive women not fulfilling criteria for antiphospholipid syndrome: a retrospective study
    Teresa Del Ross
    Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padua, Italy
    J Rheumatol 40:425-9. 2013
    ..The effect of low-dose aspirin (LDA) on pregnancy outcome in antiphospholipid (aPL)-positive women not fulfilling the criteria for antiphospholipid antibody syndrome (APS) was evaluated retrospectively...
  41. doi Overlap connective tissue disease syndromes
    Luca Iaccarino
    Division of Rheumatology, Department of Medicine, University of Padua, Italy
    Autoimmun Rev 12:363-73. 2013
    ..In this paper the most frequent OS are described with a special focus on the specific immunologic and clinical aspects. Furthermore, some personal data on anti-t-RNA synthetase syndrome and rhupus syndrome are reported...
  42. doi Emerging and critical issues in the pathogenesis of lupus
    Mariele Gatto
    Division of Rheumatology, Department of Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Autoimmun Rev 12:523-36. 2013
    ..e. genetic predisposition, B and T cell abnormalities, abnormal autoantigen availability, autoantibody generation and organ damage, relying on current knowledge and recent insights into SLE development...
  43. pmc Synovial effusion and synovial fluid biomarkers in psoriatic arthritis to assess intraarticular tumor necrosis factor-α blockade in the knee joint
    Ugo Fiocco
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Arthritis Res Ther 12:R148. 2010
    ....
  44. doi The clinical relevance of early anti-adalimumab antibodies detection in rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis: A prospective multicentre study
    Ariela Hoxha
    Rheumatology Unit, Department of Medicine, University of Padua, Via Giustiniani, 2 35128 Padova, Italy Electronic address
    Joint Bone Spine 83:167-71. 2016
    ..To evaluate the relevance of anti-adalimumab (anti-ADA) antibodies (Abs) and their relationship with clinical/laboratory features in rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA)...
  45. ncbi Influenza vaccine with adjuvant on disease activity in psoriatic arthritis patients under anti-TNF-α therapy
    Francesco Caso
    Rheumatology Unit, Department of Clinical Medicine and Surgery, University Federico II, Naples and Rheumatology Unit, Department of Medicine DIMED, University of Padova, Italy
    Clin Exp Rheumatol 34:507-12. 2016
    ..To evaluate the effects on disease activity of seasonal influenza vaccination with adjuvant in psoriatic arthritis (PsA) patients in stable disease activity on anti-TNF-α drugs as compared to not vaccinated PsA patients adequately matched...
  46. pmc Self-reported flares are predictors of radiographic progression in rheumatoid arthritis patients in 28-joint disease activity score remission: a 24-month observational study
    Francesca Ometto
    Rheumatology Unit, Department of Medicine, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy
    Arthritis Res Ther 18:89. 2016
    ..Our aim was to investigate whether overall flares (OF), self-reported flares (SRF) and short flares assessed at the visit (SF) predict radiographic progression in RA patients in DAS28 (28-joint disease activity score) remission...
  47. pmc Maternal autoantibody profiles at risk for autoimmune congenital heart block: a prospective study in high-risk patients
    Marta Tonello
    Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy
    Lupus Sci Med 3:e000129. 2016
    ..This prospective study aimed to identify antibody profiles characterising mothers with fetuses developing congenital heart block (CHB) by comparing their antibody frequencies and levels with those in unaffected mothers...
  48. ncbi Hyperuricemia, Cardiovascular Profile, and Comorbidity in Older Men and Women: The Pro.V.A. Study
    Estella Musacchio
    1 Department of Medicine DIMED, Clinica Medica 1, University of Padova, Padova, Italy
    Rejuvenation Res . 2016
    ..21-5.37) than in women (ns). Patterns of age-dependent UA increase are markedly different in men and women. HU prevalence is substantial and its association with other diseases is gender specific, connoting a peculiar clinical profile...
  49. doi Immunization with pentraxin 3 (PTX3) leads to anti-PTX3 antibody production and delayed lupus-like nephritis in NZB/NZW F1 mice
    Mariele Gatto
    Division of Rheumatology, Department of Medicine, University of Padova, Via Giustiniani 2, 35123, Padova, Italy
    J Autoimmun 74:208-216. 2016
    ..Anti-pentraxin 3 (PTX3) antibodies were associated with the absence of lupus glomerulonephritis in humans...
  50. doi Vascular perfusion kinetics by contrast-enhanced ultrasound are related to synovial microvascularity in the joints of psoriatic arthritis
    Ugo Fiocco
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy
    Clin Rheumatol 34:1903-12. 2015
    ....
  51. doi Transcriptional network profile on synovial fluid T cells in psoriatic arthritis
    Ugo Fiocco
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy
    Clin Rheumatol 34:1571-80. 2015
    ....
  52. doi Ex Vivo Signaling Protein Mapping in T Lymphocytes in the Psoriatic Arthritis Joints
    Ugo Fiocco
    From the Rheumatology Unit, Department of Medicine DIMED, University of Padua Hematology and Clinical Immunology Branch, University of Padua Department of Woman and Child Health, University of Padua, Padua Rheumatology Unit, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy and Faculty of Medicine, University Medical Center, University of Geneva, Geneva, Switzerland U Fiocco, MD, Rheumatology Unit, Department of Medicine DIMED, University of Padua V Martini, Hematology and Clinical Immunology Branch, University of Padua B Accordi, Department of Woman and Child Health, University of Padua F Caso, MD, Rheumatology Unit, Department of Medicine DIMED, University of Padua and Rheumatology Unit, Department of Clinical Medicine and Surgery, University Federico II L Costa, MD, Rheumatology Unit, Department of Medicine DIMED, University of Padua and Rheumatology Unit, Department of Clinical Medicine and Surgery, University Federico II F Oliviero, Rheumatology Unit, Department of Medicine DIMED, University of Padua A Scanu, Rheumatology Unit
    J Rheumatol Suppl 93:48-52. 2015
    ....
  53. doi Caveats and truths in genetic, clinical, autoimmune and autoinflammatory issues in Blau syndrome and early onset sarcoidosis
    Francesco Caso
    Research Center of Systemic Autoinflammatory Diseases and Behçet s Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padua, Italy
    Autoimmun Rev 13:1220-9. 2014
    ..The aim of this paper is to describe BS and EOS, focusing on their genetic, clinical, and therapeutic issues, with the ultimate goal of increasing clinicians' awareness of both of these rare but serious disorders. ..
  54. doi Metabolic syndrome and its relationship with the achievement of minimal disease activity state in psoriatic arthritis patients: an observational study
    Luisa Costa
    Rheumatology Unit, Department of Clinical Medicine and Surgery, University Federico II, Via S Pansini 5, 80131, Naples, Italy
    Immunol Res 61:147-53. 2015
    ..56, p < 0.001). Metabolic syndrome is associated with a lower probability of achieving MDA in PsA patients in therapy with anti-TNF-α...
  55. doi Current evidence in the field of the management with TNF-α inhibitors in psoriatic arthritis and concomitant hepatitis C virus infection
    Francesco Caso
    University of Padova, Department of Medicine DIMED, Rheumatology Unit, Via Giustiniani 2, 35128 Padova, Italy 39 049 8211206 39 049 8214382
    Expert Opin Biol Ther 15:641-50. 2015
    ..In the last few decades, anti-TNF-α therapy has opened new horizons in the treatment of PsA. Hence, the purpose of this review is to explore the efficacy and safety of anti-TNF-α agents in PsA and concomitant HCV infection...
  56. pmc Effect of pregnancy on serum cytokines in SLE patients
    Andrea Doria
    Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padova, 35128, Italy
    Arthritis Res Ther 14:R66. 2012
    ..The aim of this study was to evaluate an extensive panel of cytokines involved in immune regulation during pregnancy in patients with systemic lupus erythematosus (SLE) and in healthy women...
  57. doi Serological markers of erosive hand osteoarthritis
    Roberta Ramonda
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Italy
    Eur J Intern Med 24:11-5. 2013
    ....
  58. doi Predictors of Loss of Remission and Disease Flares in Patients with Axial Spondyloarthritis Receiving Antitumor Necrosis Factor Treatment: A Retrospective Study
    Ennio Lubrano
    From the Dipartimento di Medicina e Scienze della Salute Vincenzo Tiberio, Università degli Studi del Molise, Campobasso Day Hospital di Reumatologia, ASST Centro Specialistico Ortopedico Traumatologico G Pini CTO, Milan Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Matera Rheumatology Unit, Department of Clinical and Experimental Medicine DIMED, University of Padua Rheumatology Unit, Azienda Ospedaliera IRCCS di Reggio Emilia and Università di Modena e Reggio Emilia, Reggio Emilia, Italy E Lubrano, MD, PhD, Dipartimento di Medicina e Scienze della Salute Vincenzo Tiberio, Università degli Studi del Molise F Massimo Perrotta, MD, Dipartimento di Medicina e Scienze della Salute Vincenzo Tiberio, Università degli Studi del Molise M Manara, MD, PhD, Day Hospital di Reumatologia, ASST Centro Specialistico Ortopedico Traumatologico G Pini CTO S D Angelo, MD, PhD, Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera O Addimanda, MD, PhD, Rheumatology Unit, Department of Clinical and Experimental Medicine DIMED, University of Padua R Ramonda, MD, PhD, Rheumatology Unit, Department of Clinical and Experimental Medicine DIMED, University of Padua L Punzi
    J Rheumatol 43:1541-6. 2016
    ..The aim of this study was to evaluate rate and predictive factors of loss of remission and disease flare in patients with axial spondyloarthritis (axSpA) receiving antitumor necrosis factor (anti-TNF) treatment...
  59. doi The effect of different durations of remission on damage accrual: results from a prospective monocentric cohort of Caucasian patients
    Margherita Zen
    Division of Rheumatology, Department of Medicine, University of Padova, Padova, Italy
    Ann Rheum Dis . 2016
    ..To identify the shortest duration of remission associated with improved outcomes in systemic lupus erythematosus (SLE)...
  60. doi Impact of 24 months of anti-TNF therapy versus methotrexate on body weight in patients with rheumatoid arthritis: a prospective observational study
    Paolo Sfriso
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Via Giustiniani, n 2, 35128, Padova, Italy
    Clin Rheumatol 35:1615-8. 2016
    ..This increase is not shown in patients under treatment with methotrexate. A more careful evaluation of weight changes needs to be considered in RA patients under anti-TNF-α treatment. ..
  61. doi Detection of Calcium Crystals in Knee Osteoarthritis Synovial Fluid: A Comparison Between Polarized Light and Scanning Electron Microscopy
    Paola Frallonardo
    From the Rheumatology Unit, Department of Medicine DIMED Institute of Geosciences and Earth Resources, National Research Council CNR of Italy, Padova, c o Department of Geosciences and Department of Geosciences, University of Padova, Padova, Italy
    J Clin Rheumatol 22:369-71. 2016
    ..The identification of calcium crystals in synovial fluid (SF) of patients with osteoarthritis (OA) represents an important step in understanding the role of these crystals in synovial inflammation and disease progression...
  62. ncbi Quantitative imaging by pixel-based contrast-enhanced ultrasound reveals a linear relationship between synovial vascular perfusion and the recruitment of pathogenic IL-17A-F+IL-23+ CD161+ CD4+ T helper cells in
    Ugo Fiocco
    Rheumatology Unit, Department of Medicine, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy
    Clin Rheumatol . 2016
    ..The pixel-based CEUS assessment is a truly measure synovial inflammation, as a useful tool to develop quantitative imaging biomarker for monitoring target therapeutics in PsA...
  63. doi Prolonged remission in Caucasian patients with SLE: prevalence and outcomes
    Margherita Zen
    Division of Rheumatology, Department of Medicine, University of Padova, Padova, Italy
    Ann Rheum Dis 74:2117-22. 2015
    ..To assess the prevalence of prolonged remission in Caucasian patients affected with systemic lupus erythematosus (SLE) and its relationship with damage accrual...
  64. doi Plasma exchange effectively removes 52- and 60-kDa anti-Ro/SSA and anti-La/SSB antibodies in pregnant women with congenital heart block
    Marta Tonello
    Department of Medicine, Rheumatology Unit, University of Padua, Padua, Italy
    Transfusion 55:1782-6. 2015
    ..Pregnant women positive for 52- and 60-kDa anti-Ro/SSA and anti-La/SSB antibodies can suffer from congenital heart block (CHB), a passively acquired autoimmune disease...
  65. ncbi Effects of half dose etanercept (25 mg once a week) on clinical remission and radiographic progression in patients with rheumatoid arthritis in clinical remission achieved with standard dose
    Bernd Raffeiner
    Rheumatology Unit, Department of Medicine, University of Padova, Padova, Italy
    Clin Exp Rheumatol 33:63-8. 2015
    ....
  66. doi Optimizing outcome in SLE: treating-to-target and definition of treatment goals
    Andrea Doria
    Division of Rheumatology, University of Padova, Padua, Italy Electronic address
    Autoimmun Rev 13:770-7. 2014
    ....
  67. doi Refractory pemphigus foliaceus and Behçet's disease successfully treated with tocilizumab
    Francesco Caso
    Division of Rheumatology, Department of Medicine, University of Padua, Via Giustiniani 2, 35128, Padua, Italy
    Immunol Res 56:390-7. 2013
    ..Moreover, only two cases of BD and no cases of PF treated with tocilizumab have been described to date. A literature review on the use of biologic agents on patients with PF and BD was also carried out...
  68. doi Anterior chest wall involvement in early stages of spondyloarthritis: advanced diagnostic tools
    Roberta Ramonda
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padua, and Department of Radiology 1, Padua Hospital, Via Giustiniani 2, 35128 Padua, Italy
    J Rheumatol 39:1844-9. 2012
    ..Bone scan is sensitive to ACW involvement, while magnetic resonance imaging (MRI) detects early alterations in SpA. We compared the sensitivity and specificity of bone scans and MRI in assessing ACW in early SpA...
  69. doi Prognosis of scleroderma renal crisis: a long-term observational study
    Franco Cozzi
    Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy
    Nephrol Dial Transplant 27:4398-403. 2012
    ..Our aim was to evaluate the prognosis of SRC in our cohort of scleroderma patients...
  70. doi Blau syndrome, clinical and genetic aspects
    Paolo Sfriso
    Rheumatology Unit, Department of Medicine, University of Padova, Padova, Italy
    Autoimmun Rev 12:44-51. 2012
    ..Clinical and genetic aspects of the familial and the sporadic form of BS will be discussed and focused on. A description of a case study of an Italian family is also included...
  71. doi Anti-SAE antibodies in autoimmune myositis: identification by unlabelled protein immunoprecipitation in an Italian patient cohort
    Elena Tarricone
    Division of Rheumatology, Department of Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    J Immunol Methods 384:128-34. 2012
    ....
  72. ncbi Evidence of silicon dioxide crystals in synovial fluid of patients with osteoarthritis
    Francesca Oliviero
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    J Rheumatol 35:1092-5. 2008
    ..Scanning electron microscopy (SEM) was utilized in this study to characterize SF crystals in the context of knee osteoarthritis (OA)...
  73. ncbi CXCL11 in bronchoalveolar lavage fluid and pulmonary function decline in systemic sclerosis
    Paolo Sfriso
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Clin Exp Rheumatol 30:S71-5. 2012
    ..The aim of the present study was to determine whether the levels of CXCL11 in the bronchoalveolar lavage fluid (BALF) of SSc patients might be a predictor of clinically significant fibrotic lung involvement...
  74. doi The impact of knee and hip chondrocalcinosis on disability in older people: the ProVA Study from northeastern Italy
    Estella Musacchio
    Clinica Medica I, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Ann Rheum Dis 70:1937-43. 2011
    ..The role of osteoarthritis in the onset and progression of disability is well known. The impact of chondrocalcinosis on disability has never been investigated in epidemiological studies...
  75. doi Lengthening the time intervals between doses of biological agents in psoriatic arthritis patients: A single-center retrospective study
    Mariagrazia Lorenzin
    Rheumatology Unit, Department of Medicine DIMED University of Padova, Padova, Italy
    Int J Immunopathol Pharmacol 28:479-87. 2015
    ..In conclusion, lengthening the time intervals between injections of anti-TNF agents in PsA patients who reach MDA is safe, effective, cost-effective, and facilitates patient compliance. ..
  76. doi IL-1ß and IL-8 are scavenged by the hexadecylamide derivative of hyaluronic acid: a new mechanism
    Francesca Oliviero
    Rheumatology Unit, Department of Medicine, DIMED, University of Padova, Padova, Italy
    J Biomed Mater Res A 103:2823-9. 2015
    ..The HA hexadecylamide derivative was found to suppress, in vitro, the inflammatory response induced by CPP crystals and LPS by reducing the bioavailability of the two cytokines that were analyzed...
  77. doi The clinical relevance of the IgM isotype of antiphospholipid antibodies in the vascular antiphospholipid syndrome
    Teresa Del Ross
    Rheumatology Unit, Department of Medicine DIMED, Via Giustiniani 2, 35128, University of Padua, Padua, Italy Electronic address
    Thromb Res 136:883-6. 2015
    ....
  78. doi PTX3, Anti-PTX3, and Anti-C1q Autoantibodies in Lupus Glomerulonephritis
    Nicola Bassi
    Department of Medicine DIMED, Division of Rheumatology, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy
    Clin Rev Allergy Immunol 49:217-26. 2015
    ..In conclusion, PTX3 is expressed in glomeruli of LGLN patients, primarily in anti-PTX3(-) patients, where it is correlated with renal fibrosis. Anti-C1q/anti-PTX3 antibody profile seems to be useful in LGLN assessment...
  79. doi Effects of mud-bath therapy in psoriatic arthritis patients treated with TNF inhibitors. Clinical evaluation and assessment of synovial inflammation by contrast-enhanced ultrasound (CEUS)
    Franco Cozzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padova, Italy Electronic address
    Joint Bone Spine 82:104-8. 2015
    ..Other aims were to verify the risk of arthritis flare and to evaluate the effects of spa treatment on functional ability and on quality of life...
  80. doi Working the endless puzzle of hereditary autoinflammatory disorders
    Francesco Caso
    Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy
    Mod Rheumatol 24:381-9. 2014
    ....
  81. doi Serpins, immunity and autoimmunity: old molecules, new functions
    Mariele Gatto
    Division of Rheumatology, Department of Medicine, University of Padua, Via Giustiniani 2, 35128, Padua, Italy
    Clin Rev Allergy Immunol 45:267-80. 2013
    ..Here, we provide an overview of serpin origin, function, and dysfunction, focusing on human serpins and ov-serpins, with a hub on SERPINB3...
  82. doi The clinical features, diagnosis and classification of dermatomyositis
    Luca Iaccarino
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
    J Autoimmun 48:122-7. 2014
    ....
  83. doi JAK/STAT/PKCδ molecular pathways in synovial fluid T lymphocytes reflect the in vivo T helper-17 expansion in psoriatic arthritis
    Ugo Fiocco
    Rheumatology Unit, Department of Medicine, University of Padova, Via Giustiniani, 2, 35128, Padua, Italy
    Immunol Res 58:61-9. 2014
    ....
  84. doi Autoantibodies in polymyositis and dermatomyositis
    Anna Ghirardello
    Department of Medicine, Division of Rheumatology, University of Padova, Padova, Italy
    Curr Rheumatol Rep 15:335. 2013
    ..This review article provides an update of new emerging insights about the clinical and pathophysiologic role of principal autoantibodies in myositis...
  85. doi Erosive hand osteoarthritis and systemic sclerosis: a casual association?
    Roberta Ramonda
    Rheumatology Unit, Department of Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Joint Bone Spine 79:507-9. 2012
    ..One of these is an unexpected association with some autoimmune diseases. EHOA and SSc in the same patient is not uncommon, and it could speculate that there may be a genetic and autoimmune involvement...
  86. pmc High-density lipoproteins downregulate CCL2 production in human fibroblast-like synoviocytes stimulated by urate crystals
    Anna Scanu
    Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Arthritis Res Ther 12:R23. 2010
    ....
  87. doi Co-stimulatory modulation in rheumatoid arthritis: the role of (CTLA4-Ig) abatacept
    Ugo Fiocco
    Rheumatology Unit, University of Padova, Via Giustiniani 2 35128 Padova, Italy
    Autoimmun Rev 8:76-82. 2008
    ..CTLA4-Ig shows the capacity, either ex vivo or in vivo, to interrupt at multiple steps the ongoing inflammatory and destructive process, and to concur in restoring the immunoregulatory balance in RA...
  88. doi The tumor necrosis factor-{alpha}-blocking agent infliximab inhibits interleukin 1beta (IL-1beta) and IL-6 gene expression in human osteoblastic cells
    Estella Musacchio
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    J Rheumatol 36:1575-9. 2009
    ..Infliximab therapy in RA also had beneficial effects on local bone destruction and bone mineral density. We assessed effects of infliximab treatment on the bone tissue compartment and cytokine profile expression in vitro...
  89. doi A combination therapy protocol of plasmapheresis, intravenous immunoglobulins and betamethasone to treat anti-Ro/La-related congenital atrioventricular block. A case series and review of the literature
    Amelia Ruffatti
    Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy
    Autoimmun Rev 12:768-73. 2013
    ..The aim of this report was to evaluate the efficacy and safety of a combined treatment protocol used to treat 2nd and 3rd degree anti-Ro/La-related congenital atrioventricular block (CAVB)...
  90. doi Rehabilitation treatment in patients with ankylosing spondylitis stabilized with tumor necrosis factor inhibitor therapy: a randomized controlled trial
    Stefano Masiero
    Rehabilitation Unit, Department of Rehabilitation, University of Padua, Padua, Italy
    J Rheumatol 38:1335-42. 2011
    ....
  91. ncbi [Frequency of the bleeding risk in patients receiving warfarin submitted to arthrocentesis of the knee]
    G Salvati
    Cattedra e Divisione di Reumatologia, Universita degli Studi di Padova, Italia
    Reumatismo 55:159-63. 2003
    ..To evaluate the potential bleeding risks of arthrocentesis in patients with different arthropathies and taking oral anticoagulants...
  92. ncbi Recommendations of the Italian Society for Rheumatology for the use of biologic (TNF-alpha blocking) agents in the treatment of psoriatic arthritis
    C Salvarani
    Rheumatology Unit, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy
    Clin Exp Rheumatol 24:70-8. 2006
    ..To propose recommendations for the use of biologic (TNF-alpha blocking) agents in the treatment of psoriatic arthritis (PsA)...
  93. ncbi Apolipoprotein A-I and cholesterol in synovial fluid of patients with rheumatoid arthritis, psoriatic arthritis and osteoarthritis
    F Oliviero
    Department of Clinical and Experimental Medicine, University of Padova, Italy
    Clin Exp Rheumatol 27:79-83. 2009
    ..To investigate lipid and apolipoprotein (Apo) levels in synovial fluid (SF) and serum of patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and osteoarthritis (OA)...
  94. pmc Biological treatments: new weapons in the management of monogenic autoinflammatory disorders
    Antonio Vitale
    Research Center of Systemic Autoimmune and Autoinflammatory Diseases, Rheumatology Unit, Policlinico Le Scotte, University of Siena, Viale Bracci 1, 53100 Siena, Italy
    Mediators Inflamm 2013:939847. 2013
    ..Aim of this review is to synthesize the current experience and the most recent evidences about the therapeutic approach with biologic drugs in pediatric and adult patients with monogenic autoinflammatory disorders. ..
  95. doi Long-term safety of anti-TNF-α in PsA patients with concomitant HCV infection: a retrospective observational multicenter study on 15 patients
    Luisa Costa
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University Federico II, Via S Pansini 5, 80131, Naples, Italy
    Clin Rheumatol 33:273-6. 2014
    ..The data suggests that anti-TNF-α agents are effective and safe in PsA patients with concomitant HCV. We suggest that the use of anti-TNF-α agents, accompanied by close monitoring, could be a therapeutic option...
  96. doi Influence of tumor necrosis factor α inhibitors on testicular function and semen in spondyloarthritis patients
    Roberta Ramonda
    Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy
    Fertil Steril 101:359-65. 2014
    ..To evaluate sperm parameters and sexual hormones in young males affected with spondyloarthritis (SpA) before and after 1 year of anti-tumor necrosis factor (TNF) α treatment...
  97. doi Joint and bone assessment in hand osteoarthritis
    Roberta Ramonda
    Rheumatology Unit, Department of Medicine DIMED, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy
    Clin Rheumatol 33:11-9. 2014
    ..This report focuses on the laboratory and clinimetric assessments that can be used to distinguish hand OA subtypes and addresses the debatable association with low bone mineral density in osteoporosis. ..
  98. ncbi Serum and salivary neopterin and interferon-gamma in primary Sjögren's syndrome. Correlation with clinical, laboratory and histopathologic features
    Paolo Sfriso
    Department of Medical and Surgical Sciences, Section of Rheumatology, University of Padova, Italy
    Scand J Rheumatol 32:74-8. 2003
    ..To investigate serum and salivary neopterin and interferon-gamma as possible markers of immune system activation in primary Sjögren's Syndrome (pSS)...
  99. ncbi Effects of an educational-behavioral joint protection program on people with moderate to severe rheumatoid arthritis: a randomized controlled trial
    Stefano Masiero
    Department of Rehabilitation Medicine, School of Medicine, University of Padova, Padova, Italy
    Clin Rheumatol 26:2043-50. 2007
    ..This approach may efficiently complement drug therapy in these patients...
  100. ncbi Tryptophan catabolism in synovial fluid of various arthropathies and its relationship with inflammatory cytokines
    A Bertazzo
    Department of Pharmaceutical Sciences, University of Padova, Italy
    Adv Exp Med Biol 467:565-70. 1999
    ..In addition, IDO activity seems to be related with the decrease in Trp, as demonstrated by the inverse correlation found between these two substances in the SF of all patients...
  101. ncbi Psoriatic arthritis exacerbated by Salmonella infection
    L Punzi
    Division of Rheumatology, University of Padova, Italy
    Clin Rheumatol 19:167-8. 2000
    ..This case confirms the importance of infectious agents in the occurrence and course of PsA...