Maurizio Prato

Summary

Affiliation: University of Trieste
Country: Italy

Publications

  1. ncbi request reprint Translocation of bioactive peptides across cell membranes by carbon nanotubes
    Davide Pantarotto
    Institut de Biologie Moleculaire et Cellulaire, UPR9021 CNRS, Strasbourg, France
    Chem Commun (Camb) . 2004
  2. doi request reprint Positive graphene by chemical design: tuning supramolecular strategies for functional surfaces
    Caroline Hadad
    Center of Excellence for Nanostructured Materials CENMAT and INSTM, Unit of Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    Chem Commun (Camb) 50:885-7. 2014
  3. doi request reprint Peptide-based carbon nanotubes for mitochondrial targeting
    Alessia Battigelli
    Department of Chemical and Pharmaceutical Sciences, University of Trieste, Piazzale Europa 1, Trieste, 34127, Italy
    Nanoscale 5:9110-7. 2013
  4. ncbi request reprint Functionalized carbon nanotubes in drug design and discovery
    Maurizio Prato
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, 34127 Trieste, Italy
    Acc Chem Res 41:60-8. 2008
  5. ncbi request reprint Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells
    Hélène Dumortier
    CNRS UPR 9021, Institute of Molecular and Cellular Biology, Strasbourg, France
    Nano Lett 6:1522-8. 2006
  6. doi request reprint Carbon nanotubes instruct physiological growth and functionally mature syncytia: nongenetic engineering of cardiac myocytes
    Valentina Martinelli
    International Centre for Genetic Engineering and Biotechnology, Trieste, Italy
    ACS Nano 7:5746-56. 2013
  7. doi request reprint Knitting the catalytic pattern of artificial photosynthesis to a hybrid graphene nanotexture
    Mildred Quintana
    Center of Excellence for Nanostructured Materials CENMAT and INSTM, Unit of Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    ACS Nano 7:811-7. 2013
  8. ncbi request reprint Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors
    Claudia Cusan
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, I 34127, Trieste, Italy
    Farmaco 60:327-32. 2005
  9. doi request reprint Synthesis and characterization of nucleobase-carbon nanotube hybrids
    Prabhpreet Singh
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunologie et Chimie Thérapeutiques, 67000 Strasbourg, France
    J Am Chem Soc 131:13555-62. 2009
  10. doi request reprint Two-dimensional diffusion-ordered NMR spectroscopy as a tool for monitoring functionalized carbon nanotube purification and composition
    Riccardo Marega
    Center of Excellence for Nanostructured Materials CENMAT, Dipartimento di Scienze Farmaceutiche and INSTM UdR Trieste, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    ACS Nano 4:2051-8. 2010

Detail Information

Publications117 found, 100 shown here

  1. ncbi request reprint Translocation of bioactive peptides across cell membranes by carbon nanotubes
    Davide Pantarotto
    Institut de Biologie Moleculaire et Cellulaire, UPR9021 CNRS, Strasbourg, France
    Chem Commun (Camb) . 2004
    ..Functionalised carbon nanotubes are able to cross the cell membrane and to accumulate in the cytoplasm or reach the nucleus without being toxic for the cell up to 10 [micro sign]M...
  2. doi request reprint Positive graphene by chemical design: tuning supramolecular strategies for functional surfaces
    Caroline Hadad
    Center of Excellence for Nanostructured Materials CENMAT and INSTM, Unit of Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    Chem Commun (Camb) 50:885-7. 2014
    ....
  3. doi request reprint Peptide-based carbon nanotubes for mitochondrial targeting
    Alessia Battigelli
    Department of Chemical and Pharmaceutical Sciences, University of Trieste, Piazzale Europa 1, Trieste, 34127, Italy
    Nanoscale 5:9110-7. 2013
    ..The localization of the MTS-MWCNT conjugates into mitochondria was further confirmed by analyzing the isolated organelles using TEM. ..
  4. ncbi request reprint Functionalized carbon nanotubes in drug design and discovery
    Maurizio Prato
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, 34127 Trieste, Italy
    Acc Chem Res 41:60-8. 2008
    ....
  5. ncbi request reprint Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells
    Hélène Dumortier
    CNRS UPR 9021, Institute of Molecular and Cellular Biology, Strasbourg, France
    Nano Lett 6:1522-8. 2006
    ..f-CNT 3, which instead possesses reduced solubility and forms mainly stable water suspensions, preserved lymphocytes' functionality while provoking secretion of proinflammatory cytokines by macrophages...
  6. doi request reprint Carbon nanotubes instruct physiological growth and functionally mature syncytia: nongenetic engineering of cardiac myocytes
    Valentina Martinelli
    International Centre for Genetic Engineering and Biotechnology, Trieste, Italy
    ACS Nano 7:5746-56. 2013
    ..These properties are unique in the current vexing field of tissue engineering, and offer unprecedented perspectives in the development of innovative therapies for cardiac repair. ..
  7. doi request reprint Knitting the catalytic pattern of artificial photosynthesis to a hybrid graphene nanotexture
    Mildred Quintana
    Center of Excellence for Nanostructured Materials CENMAT and INSTM, Unit of Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    ACS Nano 7:811-7. 2013
    ..Our innovation is based on a noninvasive, synthetic protocol for graphene functionalization that goes beyond the ill-defined oxidation-reduction methods, allowing a definite control of the surface properties...
  8. ncbi request reprint Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors
    Claudia Cusan
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, I 34127, Trieste, Italy
    Farmaco 60:327-32. 2005
    ....
  9. doi request reprint Synthesis and characterization of nucleobase-carbon nanotube hybrids
    Prabhpreet Singh
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunologie et Chimie Thérapeutiques, 67000 Strasbourg, France
    J Am Chem Soc 131:13555-62. 2009
    ....
  10. doi request reprint Two-dimensional diffusion-ordered NMR spectroscopy as a tool for monitoring functionalized carbon nanotube purification and composition
    Riccardo Marega
    Center of Excellence for Nanostructured Materials CENMAT, Dipartimento di Scienze Farmaceutiche and INSTM UdR Trieste, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    ACS Nano 4:2051-8. 2010
    ..Complete elimination of physisorbed polyethylene glycol was achieved using diafiltration...
  11. ncbi request reprint Tuning electron transfer through translational motion in molecular shuttles
    Aurelio Mateo-Alonso
    Italian Interuniversity Consortium on Materials, Science, and Technology INSTM, Unit of Trieste, Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Angew Chem Int Ed Engl 46:3521-5. 2007
  12. doi request reprint Multiple hydrogen bond interactions in the processing of functionalized multi-walled carbon nanotubes
    Mildred Quintana
    Center of Excellence for Nanostructured Materials CENMAT, INSTM UdR di Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    ACS Nano 6:23-31. 2012
    ..These results open new possibilities toward the controlled manipulation of CNTs on surfaces, using H-bonding self-assembly as the main driving force...
  13. ncbi request reprint Photophysical and electrochemical properties of a fullerene-stoppered rotaxane
    Aurelio Mateo-Alonso
    INSTM, Unit of Trieste and Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Photochem Photobiol Sci 5:1173-6. 2006
    ..The results evidenced the strong binding interactions between the template and the macrocycle, which are also supported by molecular modelling...
  14. ncbi request reprint Synthesis, characterization, and photoinduced electron transfer in functionalized single wall carbon nanohorns
    Carla Cioffi
    INSTM, Unit of Trieste, Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    J Am Chem Soc 129:3938-45. 2007
    ..Transient absorption spectra permitted the electron-transfer process between the porphyrins and the carbon nanostructures to be highlighted...
  15. ncbi request reprint Targeted delivery of amphotericin B to cells by using functionalized carbon nanotubes
    Wei Wu
    Institut de Biologie Moleculaire et Cellulaire, UPR9021 CNRS, Immunologie et Chimie Thérapeutiques, 67084 Strasbourg, France
    Angew Chem Int Ed Engl 44:6358-62. 2005
  16. doi request reprint Carbon nanotube scaffolds tune synaptic strength in cultured neural circuits: novel frontiers in nanomaterial-tissue interactions
    Giada Cellot
    Life Science Department, B R A I N, University of Trieste, I 34127 Trieste, Italy
    J Neurosci 31:12945-53. 2011
    ..Using electrophysiological recordings and rat cultured neural networks, we describe the ability of a nanoscaled material to promote the formation of synaptic contacts and to modulate their plasticity...
  17. doi request reprint Formation of efficient catalytic silver nanoparticles on carbon nanotubes by adenine functionalization
    Prabhpreet Singh
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunologie et Chimie Thérapeutiques, Strasbourg, France
    Angew Chem Int Ed Engl 50:9893-7. 2011
    ..The catalytic efficiency of the resulting species was assessed in the oxidation of 2-methylhydroquinone to its corresponding benzoquinone, with complete recovery and without loss of activity of the catalyst...
  18. doi request reprint Carbon nanotube-nucleobase hybrids: nanorings from uracil-modified single-walled carbon nanotubes
    Prabhpreet Singh
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunologie et Chimie Thérapeutiques, Strasbourg, France
    Chemistry 17:6772-80. 2011
    ..These nanorings can be envisaged for the development of advanced electronic circuits...
  19. doi request reprint Antifungal activity of amphotericin B conjugated to carbon nanotubes
    Monica Benincasa
    Department of Life Sciences, University of Trieste, Italy
    ACS Nano 5:199-208. 2011
    ..Interestingly, the f-CNT-AMB 1 does not show any significant toxic effect on Jurkat cells at antifungal concentrations...
  20. ncbi request reprint Immunization with peptide-functionalized carbon nanotubes enhances virus-specific neutralizing antibody responses
    Davide Pantarotto
    Institut de Biologie Moleculaire et Cellulaire, UPR 9021 CNRS, Immunologie et Chimie Thérapeutiques, 15 rue Rene Descartes, 67084 Strasbourg, France
    Chem Biol 10:961-6. 2003
  21. doi request reprint Production of large graphene sheets by exfoliation of graphite under high power ultrasound in the presence of tiopronin
    Mildred Quintana
    CENMAT, INSTM UdR di Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    Chem Commun (Camb) 48:12159-61. 2012
    ..Under ultrasonication, the production of high quality graphene layers by exfoliation of graphite was achieved via addition of tiopronin as an antioxidant...
  22. doi request reprint Spinal cord explants use carbon nanotube interfaces to enhance neurite outgrowth and to fortify synaptic inputs
    Alessandra Fabbro
    Life Science Department, Center for Neuroscience B R A I N, University of Trieste, Via Giorgieri 1, I 34127 Trieste, Italy
    ACS Nano 6:2041-55. 2012
    ..On the other hand, exploring spontaneous and evoked synaptic activity unmasks an increase in synaptic efficacy in neurons located at as far as 5 cell layers from the cell-substrate interactions...
  23. doi request reprint Carbon nanotubes might improve neuronal performance by favouring electrical shortcuts
    Giada Cellot
    Life Science Department, B R A I N, University of Trieste, Via Fleming 22, I 34127, Trieste, Italy
    Nat Nanotechnol 4:126-33. 2009
    ..These considerations offer a perspective that would allow us to predict or engineer interactions between neurons and carbon nanotubes...
  24. doi request reprint Synthesis and characterization of a carbon nanotube-dendron series for efficient siRNA delivery
    M Antonia Herrero
    Center of Excellence for Nanostructured Materials, Department of Pharmaceutical Sciences, and INSTM, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 131:9843-8. 2009
    ..The work reported here highlights the fact that dendron-functionalized CNTs can be rationally designed as efficient carriers of siRNA that can eventually lead to gene silencing...
  25. doi request reprint Charge transfer reactions along a supramolecular redox gradient
    Aurelio Mateo-Alonso
    Center of Excellence for Nanostructured Materials, Italian Interuniversity Consortium on Materials Science and Technology, Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Italy
    J Am Chem Soc 130:14938-9. 2008
    ..A rotaxane scaffold is used to align three photo/electroactive units along a supramolecular redox gradient leading to a cascade of through-space charge transfer reactions...
  26. doi request reprint Microwave-induced multiple functionalization of carbon nanotubes
    Fulvio G Brunetti
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 130:8094-100. 2008
    ..The doubly functionalized SWNTs can be considered potentially useful for many interesting applications...
  27. ncbi request reprint Solid-phase synthesis and characterization of a novel fullerene-peptide derived from histone H3
    Alberto Bianco
    Institute of Molecular and Cellular Biology, UPR 9021 CNRS, 67084 Strasbourg, France
    Org Biomol Chem 1:4141-3. 2003
    ..By molecular modelling it was verified that this peptide derivative is able to retain a binding capacity to the MHC (major histocompatibility complex) molecule similar to that of the cognate epitope...
  28. ncbi request reprint Carbon nanotubes: on the road to deliver
    Alberto Bianco
    UPR 9021, CNRS, Institut de Biologie Moleculaire et Cellulaire, 15 rue Rene Descartes, F 67084, Strasbourg, France
    Curr Drug Deliv 2:253-9. 2005
    ..This opens new therapeutic and preventive opportunities to combat diseases. The scope of this review is to summarize our recent work in this rapidly growing field...
  29. doi request reprint Antibody covalent immobilization on carbon nanotubes and assessment of antigen binding
    Enrica Venturelli
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunologie et Chimie Thérapeutiques, Strasbourg 67000, France
    Small 7:2179-87. 2011
    ..These results are very relevant for the design of future receptor-targeting strategies using chemically functionalized carbon nanotubes...
  30. doi request reprint Light-induced selective deposition of Au nanoparticles on single-wall carbon nanotubes
    Mildred Quintana
    Center of Excellence on Nanostructured Materials CENMAT and INSTM, Unit of Trieste, Dipartimento di Scienze Farmaceutiche, Università degli Studi di Trieste, Piazzale Europa 1, I 34127, Trieste, Italia
    ACS Nano 4:6105-13. 2010
    ..This new technique can be useful for the preparation of nanohybrid composites with enhanced properties, as increased thermal stability, and to obtain purified SWNT...
  31. doi request reprint Functionalization of graphene via 1,3-dipolar cycloaddition
    Mildred Quintana
    Center of Excellence for Nanostructured Materials CENMAT and INSTM, Unit of Trieste, Dipartimento di Scienze Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    ACS Nano 4:3527-33. 2010
    ....
  32. ncbi request reprint Synthesis and characterization of highly water-soluble dendrofulleropyrrolidine bisadducts with DNA binding activity
    Alejandro Montellano López
    Center of Excellence for Nanostructured Materials CENMAT, Department of Chemical and Pharmaceutical Sciences, and INSTM, Unit of Trieste, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Org Lett 14:4450-3. 2012
    ..Electrophoresis studies show different DNA binding efficiencies for different adducts, some of which can be considered excellent candidates for DNA binding therapies...
  33. ncbi request reprint Design and activity of cationic fullerene derivatives as inhibitors of acetylcholinesterase
    Giorgia Pastorin
    Institute of Molecular and Cellular Biology, UPR 9021 CNRS, Strasbourg, France
    Org Biomol Chem 4:2556-62. 2006
    ..The cationic C(60) derivatives used in this study represent a new class of molecules potentially able to modulate the enzymatic activity of acetylcholinesterase...
  34. doi request reprint Endowing carbon nanotubes with biological and biomedical properties by chemical modifications
    Alessia Battigelli
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunopathologie et Chimie Thérapeutique, 67000 Strasbourg, France
    Adv Drug Deliv Rev 65:1899-920. 2013
    ..Biomolecules can be covalently grafted or non-covalently adsorbed on the nanotube surface. In addition, the inner core of CNTs can be exploited to encapsulate drugs, nanoparticles, or radioactive elements. ..
  35. doi request reprint Targeting carbon nanotubes against cancer
    Chiara Fabbro
    Center of Excellence for Nanostructured Materials, INSTM unit of Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, Universita di Trieste, Trieste, 34127, Italy
    Chem Commun (Camb) 48:3911-26. 2012
    ..The attention throughout the review is focused on the different targeting strategies proposed so far, mainly based on antibodies, but also on other specifically recognised molecules or on the application of an external magnetic field...
  36. doi request reprint Enhanced anticancer activity of multi-walled carbon nanotube-methotrexate conjugates using cleavable linkers
    Cristian Samorì
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunologie et Chimie Thérapeutiques, 67000 Strasbourg, France
    Chem Commun (Camb) 46:1494-6. 2010
    ..The new nanobio-hybrid conjugates were internalized into human breast cancer cells and it was shown that the cytotoxic activity was strongly dependent on the presence and type of linker...
  37. doi request reprint Efficient water oxidation at carbon nanotube-polyoxometalate electrocatalytic interfaces
    Francesca M Toma
    Center of Excellence for Nanostructured Materials CENMAT, INSTM, Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Nat Chem 2:826-31. 2010
    ..Our bioinspired electrode addresses the one major challenge of artificial photosynthesis, namely efficient water oxidation, which brings us closer to being able to power the planet with carbon-free fuels...
  38. doi request reprint Antibonding plasmon modes in colloidal gold nanorod clusters
    Marek Grzelczak
    Department of Chemical and Pharmaceutical Sciences, University of Trieste, P le Europa 1, 34127 Trieste Italy
    Langmuir 28:8826-33. 2012
    ..This picture opens up a number of relevant questions in nanoscience and is expected to find application in light induced self-assembly of particles with various compositions and morphologies...
  39. pmc Adhesion to carbon nanotube conductive scaffolds forces action-potential appearance in immature rat spinal neurons
    Alessandra Fabbro
    Life Science Department, University of Trieste, Trieste, Italy
    PLoS ONE 8:e73621. 2013
    ..Hence, future tissue scaffolds blended with conductive nanotubes may be exploited to promote cell differentiation and reparative pathways in neural regeneration strategies. ..
  40. ncbi request reprint Functionalized carbon nanotubes for plasmid DNA gene delivery
    Davide Pantarotto
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, 34127 Trieste, Italy
    Angew Chem Int Ed Engl 43:5242-6. 2004
  41. doi request reprint The alluring potential of functionalized carbon nanotubes in drug discovery
    Cécilia Ménard-Moyon
    CNRS, Institut de Biologie Moleculaire et Cellulaire, UPR 9021 Immunologie et Chimie Thérapeutiques, 67000 Strasbourg, France
    Expert Opin Drug Discov 5:691-707. 2010
    ..A wide variety of chemical approaches has been developed to functionalize carbon nanotubes with therapeutic molecules towards different biomedical uses...
  42. ncbi request reprint Cationic carbon nanotubes bind to CpG oligodeoxynucleotides and enhance their immunostimulatory properties
    Alberto Bianco
    Institut de Biologie Moleculaire et Cellulaire, UPR9021 CNRS, Immunologie et Chimie Thérapeutiques, 67084 Strasbourg, France
    J Am Chem Soc 127:58-9. 2005
    ..Functionalized cationic carbon nanotubes are able to form a stable complex with CpG ODN based on charge interaction and to increase the immunostimulatory activity of CpG motifs...
  43. ncbi request reprint An electrochemically driven molecular shuttle controlled and monitored by C60
    Aurelio Mateo-Alonso
    Italian Interuniversity Consortium on Materials Science and Technology INSTM, Unit of Trieste, Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127, Trieste, Italy
    Chem Commun (Camb) . 2007
    ..Herein we describe a fullerene rotaxane, in which shuttling between two well-defined and distant co-conformations is both induced and monitored by the C60 stopper...
  44. ncbi request reprint Functionalized carbon nanotubes as emerging nanovectors for the delivery of therapeutics
    Cedric Klumpp
    Institute of Molecular and Cellular Biology, UPR 9021 CNRS, 15 rue Rene Descartes, 67084 Strasbourg, France
    Biochim Biophys Acta 1758:404-12. 2006
    ..Once the cargos are carried into various cells, tissues and organs they are able to express their biological function. In this review, we will describe the potential of f-CNT to deliver different types of therapeutic molecules...
  45. ncbi request reprint Anti-HIV properties of cationic fullerene derivatives
    Silvia Marchesan
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    Bioorg Med Chem Lett 15:3615-8. 2005
    ..None of the compounds showed any inhibitory activity against a variety of DNA and RNA viruses other than HIV...
  46. doi request reprint Fullerene C₆₀ as a multifunctional system for drug and gene delivery
    Alejandro Montellano
    Center of Excellence for Nanostructured Materials CENMAT, Department of Chemical and Pharmaceutical Sciences, and INSTM, Unit of Trieste University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Nanoscale 3:4035-41. 2011
    ..Promising results have emerged in the last years, bringing fullerenes again to the front of interest. Herein, the state of the art of this emerging field is presented and illustrated with some of the most representative examples...
  47. pmc Carbon nanotubes: artificial nanomaterials to engineer single neurons and neuronal networks
    Alessandra Fabbro
    Department of Chemical and Pharmaceutical Sciences and Life Science Department, University of Trieste, Trieste, Italy
    ACS Chem Neurosci 3:611-8. 2012
    ..We focus this review on our work over several years directed to investigate the ability of carbon nanotube platforms in providing a new tool for nongenetic manipulations of neuronal performance and network signaling...
  48. ncbi request reprint A dendritic fullerene-porphyrin dyad
    Stephane Campidelli
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Photochem Photobiol Sci 5:1137-41. 2006
    ..Femto- and picosecond transient absorption permit to identify the formation of a radical ion pair while nanosecond experiments allowed the determination of the charge recombination lifetimes...
  49. ncbi request reprint Dispersion of single-walled carbon nanotubes with an extended diazapentacene derivative
    Aurelio Mateo-Alonso
    Center of Excellence for Nanostructured Materials CENMAT, Dipartimento di Scienze Farmaceutiche, INSTM UdR di Trieste, Universita di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Phys Chem A 111:12669-73. 2007
    ..This approach is very attractive for manipulation of SWCNTs for electronic applications...
  50. ncbi request reprint Applications of carbon nanotubes in drug delivery
    Alberto Bianco
    Institute of Molecular and Cellular Biology, UPR 9021 CNRS, 67084 Strasbourg, France
    Curr Opin Chem Biol 9:674-9. 2005
    ..Because functionalised CNT display low toxicity and are not immunogenic, such systems hold great potential in the field of nanobiotechnology and nanomedicine...
  51. doi request reprint Engineering of supramolecular H-bonded nanopolygons via self-assembly of programmed molecular modules
    Anna Llanes-Pallas
    Universita degli Studi di Trieste, Dipartimento di Scienze Farmaceutiche and INSTM UdR di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 131:509-20. 2009
    ....
  52. doi request reprint Diffusion-ordered NMR spectroscopy in the structural characterization of functionalized carbon nanotubes
    Riccardo Marega
    Center of Excellence for Nanostructured Materials CENMAT, Dipartimento di Scienze Farmaceutiche and INSTM UdR Trieste, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 131:9086-93. 2009
    ..The overall results show that the diffusion-based NMR spectroscopy is a fast and promising approach for the characterization of covalently modified CNT derivatives...
  53. doi request reprint Organic functionalisation and characterisation of single-walled carbon nanotubes
    Prabhpreet Singh
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunologie et Chimie Thérapeutiques, 15 rue Rene Descartes, 67000, Strasbourg, France
    Chem Soc Rev 38:2214-30. 2009
    ..In this tutorial review, we survey the covalent modification of SWCNTs with organic moieties, and illustrate the major analytical techniques routinely used to characterise the functionalised materials...
  54. ncbi request reprint Synthesis and biological properties of fullerene-containing amino acids and peptides
    Davide Pantarotto
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Italy
    Mini Rev Med Chem 4:805-14. 2004
    ..Finally, applications in medicinal chemistry of such types of amino acids and peptides will be highlighted...
  55. doi request reprint One-pot triple functionalization of carbon nanotubes
    Cécilia Ménard-Moyon
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunologie et Chimie Thérapeutiques, UPR 9021, 67000 Strasbourg, France
    Chemistry 17:3222-7. 2011
    ..The sequential removal of the protecting groups of the amine functions allows the grafting of the molecules of interest on the nanotube surface to be controlled...
  56. doi request reprint Functionalized carbon nanotubes for probing and modulating molecular functions
    Cécilia Ménard-Moyon
    Centre National de la Recherche Scientifique, Institut de Biologie Moleculaire et Cellulaire, UPR 9021 Immunologie et Chimie Thérapeutiques, 67000 Strasbourg, France
    Chem Biol 17:107-15. 2010
    ....
  57. doi request reprint Ammonium and guanidinium dendron-carbon nanotubes by amidation and click chemistry and their use for siRNA delivery
    Alessia Battigelli
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunopathologie, et Chimie Thérapeutique, 67000 Strasbourg, France Dipartimento di Scienze Chimiche e Farmaceutiche, Università di Trieste 34127, Trieste, Italy
    Small 9:3610-9. 2013
    ..The demonstration of the cell uptake capacity, the low cytotoxicity, and the ability of these cationic conjugates to silence cytotoxic genes suggests them to be promising carriers for genetic material. ..
  58. doi request reprint A simple road for the transformation of few-layer graphene into MWNTs
    Mildred Quintana
    Center of Excellence for Nanostructured Materials and INSTM, Unit of Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    J Am Chem Soc 134:13310-5. 2012
    ..This new methodology matches the long held notion that CNTs are rolled up graphene layers. The proposed mechanism is general and will lead to control the production of carbon nanostructures by simple ultrasonication treatments...
  59. ncbi request reprint [60]fullerene-pyrrolidine-N-oxides
    Peter Brough
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, 34127 Trieste, Italy
    J Org Chem 71:2014-20. 2006
    ..Preliminary details of the effects of substitution on the reactivity of the pyrrolidine ring are also reported...
  60. ncbi request reprint Interfacing neurons with carbon nanotubes: electrical signal transfer and synaptic stimulation in cultured brain circuits
    Andrea Mazzatenta
    Physiology and Pathology Department, B R A I N, University of Trieste, I 34127, Trieste, Italy
    J Neurosci 27:6931-6. 2007
    ..Our experimental results, supported by mathematical models to describe the electrical interactions occurring in SWNT-neuron hybrid systems, clearly indicate that SWNTs can directly stimulate brain circuit activity...
  61. doi request reprint Selective organic functionalization of graphene bulk or graphene edges
    Mildred Quintana
    Center of Excellence for Nanostructured Materials CENMAT, INSTM UdR di Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    Chem Commun (Camb) 47:9330-2. 2011
    ..Graphene sheets have been functionalized with a PAMAM dendron, finding that graphene can be efficiently functionalized all over the surface, or only at the edges, depending on the reactions used in the functionalization process...
  62. ncbi request reprint Carbon nanotube substrates boost neuronal electrical signaling
    Viviana Lovat
    Dipartimento di Scienze Farmaceutiche, Piazzale Europa 1, Trieste, Italy
    Nano Lett 5:1107-10. 2005
    ..The increase in the efficacy of neural signal transmission may be related to the specific properties of CNT materials, such as the high electrical conductivity...
  63. ncbi request reprint Hemolytic effects of water-soluble fullerene derivatives
    Susanna Bosi
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa, 1 34127 Trieste, Italy
    J Med Chem 47:6711-5. 2004
    ..A validation of these experimental observations has been performed by theoretical studies in which hydrophilic and hydrophobic surface areas were correlated quantitatively with hemolytic properties...
  64. doi request reprint From 2D to 3D: novel nanostructured scaffolds to investigate signalling in reconstructed neuronal networks
    Susanna Bosi
    Department of Chemical and Pharmaceutical Sciences, University of Trieste, Trieste Italy
    Sci Rep 5:9562. 2015
    ..Our 3D system represents a simple and reliable construct, able to improve the complexity of current tissue culture models...
  65. doi request reprint Carbon nanotubes in neuroregeneration and repair
    Alessandra Fabbro
    Life Science Department, University of Trieste, Via Giorgieri 1, I 34127 Trieste, Italy Electronic address
    Adv Drug Deliv Rev 65:2034-44. 2013
    ....
  66. ncbi request reprint Reversible microwave-assisted cycloaddition of aziridines to carbon nanotubes
    Fulvio G Brunetti
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 129:14580-1. 2007
    ..With our procedure, we easily scale-up the reaction up to 250 mg of functionalized MWNT in 1 h. We also provide an indirect proof of the covalent sidewall functionalization of the tubes...
  67. doi request reprint Interfacing neurons with carbon nanotubes: (re)engineering neuronal signaling
    Alessandra Fabbro
    Life Science Department, Center for Neuroscience B R A I N, University of Trieste, TS, Italy
    Prog Brain Res 194:241-52. 2011
    ..Therefore, it is particularly relevant to improve our knowledge on the impact on neuronal performance of interfacing nerve cells with CNTs...
  68. ncbi request reprint Synthesis and anti-HIV properties of new water-soluble bis-functionalized[60]fullerene derivatives
    Susanna Bosi
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    Bioorg Med Chem Lett 13:4437-40. 2003
    ..The presence of a quaternary pyrrolidinium nitrogen is essential to increase solubility...
  69. doi request reprint An atom-economical approach to functionalized single-walled carbon nanotubes: reaction with disulfides
    Zois Syrgiannis
    Center of Excellence for Nanostructured Materials CENMAT, INSTM, Unit of Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, 34127 Trieste Italy
    Angew Chem Int Ed Engl 52:6480-3. 2013
    ..One advantage of this method is that any unreacted disulfide can be recovered by filtration...
  70. ncbi request reprint Synthesis and biological evaluation of new phenidone analogues as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors
    Claudia Cusan
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, I 34127, Trieste, Italy
    Farmaco 60:7-13. 2005
    ..The absence of activity vs. human 5-LOX strongly suggests a re-consideration of phenidone and its analogs as 5-LOX inhibitors in humans...
  71. doi request reprint Carbon nanotubes promote growth and spontaneous electrical activity in cultured cardiac myocytes
    Valentina Martinelli
    International Centre for Genetic Engineering and Biotechnology, Trieste, Italy
    Nano Lett 12:1831-8. 2012
    ..Furthermore, we observed changes in the electrophysiological properties of cardiomyocytes, suggesting that carbon nanotubes are able to promote cardiomyocyte maturation...
  72. ncbi request reprint Synthesis, structural characterization, and immunological properties of carbon nanotubes functionalized with peptides
    Davide Pantarotto
    Institute of Molecular and Cellular Biology, UPR 9021 CNRS, 67084 Strasbourg, France
    J Am Chem Soc 125:6160-4. 2003
    ..In addition, this peptide-NT conjugate is immunogenic, eliciting antibody responses of the right specificity. Such a system could be greatly advantageous for diagnostic purposes and could find future applications in vaccine delivery...
  73. ncbi request reprint Oligonucleotides and oligonucleotide conjugates: a new approach for cancer treatment
    Tatiana Da Ros
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    Curr Med Chem 12:71-88. 2005
    ....
  74. ncbi request reprint In vitro behavior of multifunctionalized fullerene-warfarin conjugates
    Marina Zacchigna
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Nanosci Nanotechnol 9:6210-21. 2009
    ..We have chosen warfarin as a model compound because it a widely used drug. We have analyzed the stability in vitro of the conjugates and found that the drug is released from the carbon support only after incubation in mouse plasma...
  75. ncbi request reprint Macromolecular properties of cepacian in water and in dimethylsulfoxide
    Yury Herasimenka
    Department of Biochemistry, Biophysics and Macromolecules Chemistry, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy
    Carbohydr Res 343:81-9. 2008
    ..These interactions were attributed to hydrogen bonding and contributed to structure rigidity...
  76. doi request reprint Making carbon nanotubes biocompatible and biodegradable
    Alberto Bianco
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunologie et Chimie Thérapeutiques, Strasbourg, 67000, France
    Chem Commun (Camb) 47:10182-8. 2011
    ..This article highlights recent advances that can act as paradigm-shifts towards the design of biocompatible and biodegradable functionalised carbon nanotubes and allow their translation into the clinic...
  77. ncbi request reprint Fullerenes: multitask components in molecular machinery
    Aurelio Mateo-Alonso
    Dipartimento di Scienze Farmaceutiche and Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali INSTM, Unità di Trieste, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Angew Chem Int Ed Engl 46:8120-6. 2007
    ..Such molecular motion can be employed to modulate light-driven electron-transfer events, extending the potential applications of molecular machines to the typical fields of application of fullerenes...
  78. doi request reprint Efficient modulation of the third order nonlinear optical properties of fullerene derivatives
    Aurelio Mateo-Alonso
    Center of Excellence for Nanostructured Materials, Dipartimento di Scienze Farmaceutiche and Italian Interuniversity Consortium on Materials Science and Technology, Unit of Trieste, Universita degli Studi di Trieste, Italy
    J Am Chem Soc 130:1534-5. 2008
  79. ncbi request reprint Liquid-crystalline bisadducts of [60]fullerene
    Stephane Campidelli
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Org Chem 71:7603-10. 2006
    ..Therefore, the bisadducts form monolayered smectic A phases. The title compounds are promising supramolecular materials as they combine the self-organizing behavior of liquid crystals with the properties of fullerene...
  80. ncbi request reprint Dendrimer-functionalized single-wall carbon nanotubes: synthesis, characterization, and photoinduced electron transfer
    Stephane Campidelli
    INSTM and Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 128:12544-52. 2006
    ..Complementary transient absorption measurements not only corroborate the fast decay of the photoexcited tetraphenylporphyrin but also confirm that intraconjugate charge separation evolves from the excited porphyrin to the SWNTs...
  81. ncbi request reprint Reverse shuttling in a fullerene-stoppered rotaxane
    Aurelio Mateo-Alonso
    INSTM, Unit of Trieste, and Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Org Lett 8:5173-6. 2006
    ..The reverse shuttling is confirmed by NMR spectroscopy and can be monitored by cyclic voltammetry. The electrochemically generated anions on the fullerene moiety are stabilized by the closer proximity of the macrocycle...
  82. ncbi request reprint Highly sensitive electrochemiluminescent nanobiosensor for the detection of palytoxin
    Valeria Anna Zamolo
    Center of Excellence on Nanostructured Materials, Department of Chemical and Pharmaceutical Sciences, and INSTM, Unit of Trieste, University of Trieste, P le Europa 1, 34127 Trieste, Italy
    ACS Nano 6:7989-97. 2012
    ..2 μg/kg of mussel meat) more than 2 orders of magnitude more sensitive than that of the commonly used detection techniques, such as LC-MS/MS...
  83. doi request reprint Multimode assembly of phenanthroline nanowires decorated with gold nanoparticles
    Marek Grzelczak
    Center of Excellence for Nanostructured Materials CENMAT and INSTM, Unit of Trieste, Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    Chem Commun (Camb) 46:9122-4. 2010
    ....
  84. ncbi request reprint Multiwalled carbon nanotubes drive the activity of metal@oxide core-shell catalysts in modular nanocomposites
    Matteo Cargnello
    Department of Chemical and Pharmaceutical Sciences, INSTM, Center of Excellence for Nanostructured Materials, University of Trieste, Via L Giorgieri 1, 34127 Trieste, Italy
    J Am Chem Soc 134:11760-6. 2012
    ..The modular approach shown here demonstrates that high-performance catalytic materials can be obtained through the precise organization of nanoscale building blocks...
  85. doi request reprint Trimodular engineering of linear supramolecular miniatures on Ag(111) surfaces controlled by complementary triple hydrogen bonds
    Anna Llanes-Pallas
    Dip Scienze Farmaceutiche and INSTM UdR di Trieste, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Angew Chem Int Ed Engl 47:7726-30. 2008
  86. ncbi request reprint Solid-phase synthesis of fullerene-peptides
    Davide Pantarotto
    Department of Pharmaceutical Sciences, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 124:12543-9. 2002
    ..aureus and also lysed erythrocytes. The availability of a fullero-amino acid easily useable in the SPPS of fullero-peptides may thus open the way to the synthesis of new types of biologically active oligomers...
  87. ncbi request reprint Fullerene derivatives: an attractive tool for biological applications
    Susanna Bosi
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Eur J Med Chem 38:913-23. 2003
    ..This action, together with the direct electron transfer from excited state of fullerene and DNA bases, can be used to cleave DNA. In this review we report the most recent aspects of fullerene biological applications...
  88. ncbi request reprint A carbon nano-onion-ferrocene donor-acceptor system: synthesis, characterization and properties
    Carla T Cioffi
    Center of Excellence on Nanostructured Materials CENMAT, Dipartimento di Scienze Farmaceutiche, , Piazzale Europa 1, 34127 Trieste, Italy
    Chemistry 15:4419-27. 2009
    ..At high energy, emission comes from CNOs with smaller external shells and a higher degree of functionalization...
  89. pmc Supramolecular self-assembled fullerene nanostructures
    Vasilios Georgakilas
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Proc Natl Acad Sci U S A 99:5075-80. 2002
    ..The efficient method to fabricate almost perfect and uniformly shaped nanotubular crystals, which order spontaneously by self-assembly, opens the way to the possibility of exploiting the fullerene properties at the nanometer scale...
  90. ncbi request reprint Microscopic and spectroscopic characterization of paintbrush-like single-walled carbon nanotubes
    Davide Bonifazi
    Dipartimento di Scienze Farmaceutiche and INSTM UdR Trieste, Universita degli Studi di Trieste, Italy
    Nano Lett 6:1408-14. 2006
    ..Thermogravimetric analysis (TGA), steady-state electronic absorption (UV-vis-NIR), and Raman spectroscopic studies confirm the STM observations...
  91. ncbi request reprint Spectroscopic characterization of photolytically generated radical ion pairs in single-wall carbon nanotubes bearing surface-immobilized tetrathiafulvalenes
    M Angeles Herranz
    Departamento de Quimica Organica I, Facultad de Quimica, Universidad Complutense de Madrid, E 28040 Madrid, Spain
    J Am Chem Soc 130:66-73. 2008
    ..New conduction band electrons, injected from photoexcited exTTF, shift the transitions that are associated with the van Hove singularities to lower energies...
  92. ncbi request reprint Supramolecular hybrids of [60]fullerene and single-wall carbon nanotubes
    Dirk M Guldi
    Lehrstuhl für Physikalische Chemie I, Universitat Erlangen Nurnberg, Egerlandstr 3, 91058 Erlangen, Germany
    Chemistry 12:3975-83. 2006
    ....
  93. ncbi request reprint Functional single-wall carbon nanotube nanohybrids--associating SWNTs with water-soluble enzyme model systems
    Dirk M Guldi
    Institute for Physical and Theoretical Chemistry, Egerlandstrasse 3, 91058 Erlangen, Germany
    J Am Chem Soc 127:9830-8. 2005
    ..Particularly beneficial are charge recombination dynamics that are located deep in the Marcus-inverted region. We include, for the first time, work devoted to exploring and testing FeP(8)(+) and CoP(8)(+) in donor-acceptor nanohybrids...
  94. ncbi request reprint Thermal stripping of supramolecular structures: C60 nanorods
    Michael Mannsberger
    Institut fur Materialphysik, Universitat Wien, A 1090 Wien, Strudlhofgasse 4, Austria
    J Nanosci Nanotechnol 5:198-203. 2005
    ..Synthesizing fullerenic polymers in this way can lead to several applications...
  95. ncbi request reprint Ordering fullerene materials at nanometer dimensions
    Dirk M Guldi
    Institute for Physical and Theoretical Chemistry, Universitat Erlangen, 91058 Erlangen, Germany
    Acc Chem Res 38:38-43. 2005
    ....
  96. ncbi request reprint Electrostatic complexation and photoinduced electron transfer between Zn-cytochrome c and [olyanionic fullerene dendrimers
    Martin Braun
    Institut für Organische Chemie Universität Erlangen Nürnberg Henkestrasse 42, 91054 Erlangen, Germany
    Chemistry 9:3867-75. 2003
    ..These findings were also supported by circular dichroism as well as by extensive molecular dynamics (MD) simulations...
  97. ncbi request reprint Dispersable carbon nanotube/gold nanohybrids: evidence for strong electronic interactions
    G M Aminur Rahman
    University of Notre Dame, Radiation Laboratory, Notre Dame, IN 46556, USA
    Small 1:527-30. 2005
  98. doi request reprint Singling out the electrochemistry of individual single-walled carbon nanotubes in solution
    Demis Paolucci
    INSTM, Unit of Bologna, Dipartimento di Chimica, Universita di Bologna, Via Selmi 2, I 40126 Bologna, Italy
    J Am Chem Soc 130:7393-9. 2008
    ....
  99. doi request reprint Covalent assembly and micropatterning of functionalized multiwalled carbon nanotubes to monolayer-modified Si(111) surfaces
    Bruno Fabre
    Université de Rennes 1 and CNRS UMR 6226 Sciences Chimiques de Rennes, Matiere Condensee et Systemes Electroactifs MaCSE, Campus de Beaulieu, 35042 Rennes Cedex, France
    Langmuir 24:6595-602. 2008
    ..In particular, it is demonstrated that the MWNT patterns allow a faster charge transfer which is consistent with the results obtained for the uniformly modified surfaces...
  100. doi request reprint Multipurpose organically modified carbon nanotubes: from functionalization to nanotube composites
    Vasilios Georgakilas
    Institute of Materials Science, N C S R Demokritos, GR 15310 Agia Paraskevi Athens, Greece
    J Am Chem Soc 130:8733-40. 2008
    ..Additionally, the functionalized CNTs could easily be combined with polymers and layered aluminosilicate clay minerals to give homogeneous, coherent, transparent CNT thin films and gels...
  101. ncbi request reprint Separation of metallic and semiconducting single-walled carbon nanotubes via covalent functionalization
    Stephane Campidelli
    Laboratoire d Electronique Moleculaire, CEA Saclay, 91191 Gif sur Yvette, France
    Small 3:1672-6. 2007