Affiliation: University of Rome La Sapienza
- Recommendations on the use of exercise testing in clinical practiceP Palange
Servizio di Fisiopatologia Respiratoria, Dipartimento di Medicina Clinica, University of Rome La Sapienza, Rome, Italy
Eur Respir J 29:185-209. 2007..intolerance be sought?"; 2) "Which particular form of test should be asked for?"; and 3) "What cluster of variables should be selected when evaluating prognosis for a particular disease or the effect of a particular intervention?"..
- INDACO project: a pilot study on incidence of comorbidities in COPD patients referred to pneumology unitsGiorgio Fumagalli
Pulmonary Department of San Filippo Neri General Hospital, Rome, Italy
Multidiscip Respir Med 8:28. 2013....
- Management of COPD: surgical optionsP Palange
Dipartimento di Medicina Clinica, University La Sapienza, v le Universita 37, I 00185 Rome, Italy
Respiration 68:335-42. 2001..The aim of this brief review is to summarize the available knowledge on the effects of LVRS, the criteria for patient selection, short- versus long-term effects and, finally, to propose future directions in this field...
- Effect of heliox on lung dynamic hyperinflation, dyspnea, and exercise endurance capacity in COPD patientsPaolo Palange
Dipartimento di Medicina Clinica, Servizio di Fisiopatologia Respiratoria, Universita La Sapienza, v le Universita 37, 00185 Rome, Italy
J Appl Physiol (1985) 97:1637-42. 2004..71; P < 0.01). In chronic obstructive pulmonary disease, heliox breathing improves high-intensity exercise endurance capacity by increasing maximal ventilatory capacity and by reducing lung DH and Dys...
- Circulating haemopoietic and endothelial progenitor cells are decreased in COPDP Palange
Dipartimento di Medicina Clinica, University La Sapienza, Viale Università 37, Rome, 00185 Italy
Eur Respir J 27:529-41. 2006..In conclusion, circulating CD34+ cells and endothelial progenitors were decreased in chronic obstructive pulmonary disease patients and could be correlated with disease severity...
- Effect of reduced body weight on muscle aerobic capacity in patients with COPDP Palange
Dipartimento di Medicina Clinica, University of Rome La Sapienza, Italy
Chest 114:12-8. 1998..In COPD, the effect of reduced body mass on muscle aerobic capacity has not been investigated (to our knowledge)...
- Ventilatory and metabolic adaptations to walking and cycling in patients with COPDP Palange
Dipartimento di Medicina Clinica, University of Rome La Sapienza, 00185 Rome, Italy
J Appl Physiol (1985) 88:1715-20. 2000..In COPD, reduced walking capacity is associated with an excessively high ventilatory demand. Decreased pulmonary gas exchange efficiency and arterial hypoxemia are likely to be responsible for the observed findings...
- Cardiopulmonary exercise testing in the functional and prognostic evaluation of patients with pulmonary diseasesA M Ferrazza
Department of Clinical Medicine, Pulmonary Lung Function Unit, Sapienza University of Rome, Viale Università 37, Rome, Italy
Respiration 77:3-17. 2009..Moreover, useful information on the effects of therapeutic interventions may be obtained by CPET by studying the changes in endurance capacity during high-intensity constant work rate protocols...
- Clinical use of Heliox in asthma and COPDG Valli
Dipartimento Medicina Clinica, Universita La Sapienza, Roma, Italy
Monaldi Arch Chest Dis 67:159-64. 2007..Despite the encouraging results, Heliox use in routine practice remains controversial because of technical implications and high costs...
- Exercise intolerance at high altitude (5050 m): critical power and W'G Valli
Department of Clinical Medicine, University of Rome La Sapienza, Viale dell Universita, 37 00185 Rome, Italy
Respir Physiol Neurobiol 177:333-41. 2011..8±1.3; WR(2): 8.8±0.8 vs. 5.3±1.2; WR(3): 9.3±1.0 vs. 5.3±1.5). The CP reduction is consistent with a reduced O(2) availability; that of W' with reduced muscle-venous O(2) storage, exacerbated by ventilatory limitation and dyspnea...
- Water and sodium imbalance in COPD patientsG Valli
Servizio di Fisiopatologia Respiratoria Dipartimento di Medicina Clinica, University of Rome La Sapienza V le dell Università 37, 00185 Rome, Italy
Monaldi Arch Chest Dis 61:112-6. 2004..The aim of this brief review is to highlight the current knowledge on renal/hormonal abnormalities in COPD and their therapeutic implications...
- Circulating endothelial progenitor cells and chronic pulmonary diseasesA Huertas
Dipartimento di Medicina Clinica, La Sapienza University, Rome, Italy
Eur Respir J 37:426-31. 2011..The aim is to improve understanding as to the possible role of EPCs in COPD pathophysiology. This may help in the identification of novel diagnostic and therapeutic tools in COPD...
- Pathophysiological adaptations to walking and cycling in primary pulmonary hypertensionG Valli
Department of Clinical Medicine, Universita La Sapienza, v le Universita 37, 00185, Rome, Italy
Eur J Appl Physiol 102:417-24. 2008..Tolerance to W exercise is limited by high ventilatory response and dyspnea sensation. W should be used to assess the degree of lung gas exchange inefficiency and arterial O(2) desaturation during exercise...
- Skeletal muscle dysfunction in chronic obstructive pulmonary diseaseE Berton
Servizio di Fisiopatologia Respiratoria, Dipartimento di Medicina Clinica, , Roma, Italy
Monaldi Arch Chest Dis 56:418-22. 2001..The focus of this review is to highlight the current knowledge on skeletal muscle dysfunction in COPD and briefly summarize the possible therapeutic implications...
- Effect of acetazolamide on post-NIV metabolic alkalosis in acute exacerbated COPD patientsV Fontana
Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy
Eur Rev Med Pharmacol Sci 20:37-43. 2016..However, it may induce post-hypercapnic metabolic alkalosis (MA). This study aims to evaluate the effect of acetazolamide (ACET) in AECOPD patients treated with NIV...
- Exercise physiology in COPDR Antonucci
Servizio di Fisiopatologia Respiratoria, Dipartimento di Medicina Clinica, Universita La Sapienza, Roma, v le Università, 37, 00185 Roma, Italy
Monaldi Arch Chest Dis 59:134-9. 2003..The aim of this review is to briefly discuss current views on the mechanisms responsible for the reduced ability to exercise and the rationale for exercise rehabilitation in COPD patients...
- Intrarenal hemodynamic and oxidative stress in patients with obstructive sleep apnea syndromeL Sardo
Department of Clinical Medicine, Sapienza University of Rome, Viale dell Universita 37, 00185, Rome, Italy
Sleep Breath 19:1205-12. 2015..Furthermore, we evaluated the effect of a CPAP therapy on these endpoints...
- Rhinitis and asthma in athletes: an ARIA document in collaboration with GA2LENS Bonini
IRCCS San Raffale, Rome, Italy
Allergy 61:681-92. 2006....
- Role of hyperinflation vs. deflation on dyspnoea in severely to extremely obese subjectsI Romagnoli
Department of Pulmonary Rehabilitation, Fondazione Don C Gnocchi, Florence, Italy
Acta Physiol (Oxf) 193:393-402. 2008..To test the hypothesis that obese individuals may either hyperinflate or deflate the lung when exercising. In both cases breathlessness is an inescapable consequence...
- Outcomes for COPD pharmacological trials: from lung function to biomarkersM Cazzola
Unit of Respiratory Diseases, Dept of Internal Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
Eur Respir J 31:416-69. 2008..Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations...
- Treatment of exercise-induced asthma, respiratory and allergic disorders in sports and the relationship to doping: Part II of the report from the Joint Task Force of European Respiratory Society (ERS) and European Academy of Allergy and Clinical ImmunologK H Carlsen
Voksentoppen, Department of Paediatrics, Faculty of Medicine, University of Oslo, Rikshospitalet, Norwegian School of Sport Sciences, Oslo, Norway
Allergy 63:492-505. 2008....