Rugge Massimo

Summary

Affiliation: University of Padova
Country: Italy

Publications

  1. ncbi request reprint Helicobacter pylori CagA status, mucosal oxidative damage and gastritis phenotype: a potential pathway to cancer?
    Fabio Farinati
    Dipartimento di Scienze Chirurgiche e Gastroenterologiche Sezione di Gastroenterologia, Universita degli Studi di Padova, Italy
    Helicobacter 8:227-34. 2003
  2. doi request reprint Gastric Cancer Risk in Patients with Helicobacter pylori Infection and Following Its Eradication
    Massimo Rugge
    Surgical Pathology and Cytopathology Unit, Department of Medicine DIMED, University of Padova, Via Aristide Gabelli, 61, Padova 35121, Italy Electronic address
    Gastroenterol Clin North Am 44:609-24. 2015
  3. doi request reprint Individual risk stratification of gastric cancer: evolving concepts and their impact on clinical practice
    Massimo Rugge
    Department of Medicine, DIMED, Surgical Pathology and Cytopathology Unit, University of Padua, 35100 Padua, Italy Electronic address
    Best Pract Res Clin Gastroenterol 28:1043-53. 2014
  4. pmc Impact of microRNAs on regulatory networks and pathways in human colorectal carcinogenesis and development of metastasis
    Silvia Pizzini
    Oncology and Immunology Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
    BMC Genomics 14:589. 2013
  5. pmc MicroRNA Expression Profiling in the Histological Subtypes of Barrett's Metaplasia
    Matteo Fassan
    1 Department of Medicine DIMED, Surgical Pathology and Cytopathology Unit, University of Padua, Padua, Italy 2 Department of Surgical, Oncological and Gastroenterological Sciences DiSCOG, General Oncology Unit, University of Padua, Padua, Italy
    Clin Transl Gastroenterol 4:e34. 2013
  6. pmc Pancreatic mucinous cystic tumor in Turner syndrome: How a tumor bends to a genetic disease
    Marco Pizzi
    Department of Medicine DIMED, Surgical Pathology and Cytopathology Unit, University of Padova, Italy
    Int J Surg Case Rep 4:1028-31. 2013
  7. pmc Programmed cell death 4 (PDCD4) expression during multistep Barrett's carcinogenesis
    Matteo Fassan
    Department of Medical Diagnostic Sciences, University of Padova, Padova, Italy
    J Clin Pathol 63:692-6. 2010
  8. doi request reprint Helicobacter pylori Infection, Intestinal Metaplasia, and Gastric Cancer Risk in Eastern Siberia
    Vladislav Vladimirovich Tsukanov
    State Scientific Medical Research Institute for Northern Problems of Siberian Division of Russian Academy of Medical Sciences, Krasnoyarsk, Russia Khakass State University, Abakan, Russia
    Helicobacter 16:107-12. 2011
  9. pmc Oxidative DNA damage correlates with cell immortalization and mir-92 expression in hepatocellular carcinoma
    Romilda Cardin
    Department of Surgery, Oncology and Gastroenterology, Section of Gastroenterology, University of Padova, Via Giustiniani 2, Padova 35128, Italy
    BMC Cancer 12:177. 2012
  10. doi request reprint Precancerous lesions in the stomach: from biology to clinical patient management
    Massimo Rugge
    Department of Medicine DIMED, Surgical Pathology and Cytopathology Unit, University of Padova, Padova, Italy
    Best Pract Res Clin Gastroenterol 27:205-23. 2013

Detail Information

Publications114 found, 100 shown here

  1. ncbi request reprint Helicobacter pylori CagA status, mucosal oxidative damage and gastritis phenotype: a potential pathway to cancer?
    Fabio Farinati
    Dipartimento di Scienze Chirurgiche e Gastroenterologiche Sezione di Gastroenterologia, Universita degli Studi di Padova, Italy
    Helicobacter 8:227-34. 2003
    ..Oxidative DNA damage is associated with Helicobacter pylori infection, atrophy and intestinal metaplasia. H. pylori-cagA-positive strains are associated with the highest risk of gastric cancer...
  2. doi request reprint Gastric Cancer Risk in Patients with Helicobacter pylori Infection and Following Its Eradication
    Massimo Rugge
    Surgical Pathology and Cytopathology Unit, Department of Medicine DIMED, University of Padova, Via Aristide Gabelli, 61, Padova 35121, Italy Electronic address
    Gastroenterol Clin North Am 44:609-24. 2015
    ..The reversibility of inflammatory lesions has been supported by undeniable evidence; the regression of mucosal atrophy/metaplasia has also been confirmed by several recent histologic studies. ..
  3. doi request reprint Individual risk stratification of gastric cancer: evolving concepts and their impact on clinical practice
    Massimo Rugge
    Department of Medicine, DIMED, Surgical Pathology and Cytopathology Unit, University of Padua, 35100 Padua, Italy Electronic address
    Best Pract Res Clin Gastroenterol 28:1043-53. 2014
    ..Multidisciplinary diagnostic approaches integrating endoscopy, serology, histology and molecular profiling currently appears as the most appropriate approach for patients' stratification into different GC risk classes. ..
  4. pmc Impact of microRNAs on regulatory networks and pathways in human colorectal carcinogenesis and development of metastasis
    Silvia Pizzini
    Oncology and Immunology Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
    BMC Genomics 14:589. 2013
    ....
  5. pmc MicroRNA Expression Profiling in the Histological Subtypes of Barrett's Metaplasia
    Matteo Fassan
    1 Department of Medicine DIMED, Surgical Pathology and Cytopathology Unit, University of Padua, Padua, Italy 2 Department of Surgical, Oncological and Gastroenterological Sciences DiSCOG, General Oncology Unit, University of Padua, Padua, Italy
    Clin Transl Gastroenterol 4:e34. 2013
    ..This study investigates miRNA expression in the histological spectrum of esophageal columnar metaplastic changes, specifically addressing the biological profile of GM vs. IM...
  6. pmc Pancreatic mucinous cystic tumor in Turner syndrome: How a tumor bends to a genetic disease
    Marco Pizzi
    Department of Medicine DIMED, Surgical Pathology and Cytopathology Unit, University of Padova, Italy
    Int J Surg Case Rep 4:1028-31. 2013
    ..On histology, MCNs concurrently show an epithelial mucosecreting component with ovarian-type stromal cells...
  7. pmc Programmed cell death 4 (PDCD4) expression during multistep Barrett's carcinogenesis
    Matteo Fassan
    Department of Medical Diagnostic Sciences, University of Padova, Padova, Italy
    J Clin Pathol 63:692-6. 2010
    ..To test the contribution of programmed cell death 4 (PDCD4) tumour suppressor gene in Barrett's carcinogenesis...
  8. doi request reprint Helicobacter pylori Infection, Intestinal Metaplasia, and Gastric Cancer Risk in Eastern Siberia
    Vladislav Vladimirovich Tsukanov
    State Scientific Medical Research Institute for Northern Problems of Siberian Division of Russian Academy of Medical Sciences, Krasnoyarsk, Russia Khakass State University, Abakan, Russia
    Helicobacter 16:107-12. 2011
    ..The incidence of gastric cancer (GC) is extremely high in Russia and eastern Siberia, where information on the epidemiology of Helicobacter pylori infection is fragmentary...
  9. pmc Oxidative DNA damage correlates with cell immortalization and mir-92 expression in hepatocellular carcinoma
    Romilda Cardin
    Department of Surgery, Oncology and Gastroenterology, Section of Gastroenterology, University of Padova, Via Giustiniani 2, Padova 35128, Italy
    BMC Cancer 12:177. 2012
    ....
  10. doi request reprint Precancerous lesions in the stomach: from biology to clinical patient management
    Massimo Rugge
    Department of Medicine DIMED, Surgical Pathology and Cytopathology Unit, University of Padova, Padova, Italy
    Best Pract Res Clin Gastroenterol 27:205-23. 2013
    ..This paper addresses the epidemiology, pathology, molecular profiling, and clinical management of advanced precancerous gastric lesions. ..
  11. ncbi request reprint MicroRNA dysregulation in esophageal neoplasia: the biological rationale for novel therapeutic options
    Matteo Fassan
    Department of Medicine DIMED, Surgical Pathology and Cytopathology Unit, University of Padua, Padua PD, Italy
    Curr Pharm Des 19:1236-41. 2013
    ..In addition to these valuable features, miRNAs have been proposed as innovative therapeutics per se and as plausible biological targets in new treatment strategies...
  12. doi request reprint Autoimmune gastritis: histology phenotype and OLGA staging
    M Rugge
    Department of Medicine, University of Padua, PD, Italy
    Aliment Pharmacol Ther 35:1460-6. 2012
    ..Among Western populations, the declining incidence of Helicobacter pylori infection coincides with a growing clinical impact of autoimmune gastritis...
  13. doi request reprint Isolated tumor cells in regional lymph nodes as relapse predictors in stage I and II colorectal cancer
    Claudia Mescoli
    Universita degli Studi di Padova, Padova, Italy
    J Clin Oncol 30:965-71. 2012
    ..Approximately 15% to 20% of patients without nodal metastases (pN0) develop recurrent disease. In this study, we tested the prognostic significance of isolated tumor cells (ITCs) in LNs of patients with pN0 CRC (stages I and II)...
  14. pmc CDX2 hox gene product in a rat model of esophageal cancer
    Giuseppe Ingravallo
    Department of Medical Diagnostic Sciences and Special Therapies, Pathology Unit, University of Padova, Padova, Italy
    J Exp Clin Cancer Res 28:108. 2009
    ..Experimental models of longstanding esophageal reflux of duodenal-gastric contents may provide important information on the biological sequence of the Barrett's oncogenesis...
  15. pmc MicroRNA expression profiling of male breast cancer
    Matteo Fassan
    Department of Urology, Thomas Jefferson University Kimmel Cancer Center, 1112 College Building, 1025 Walnut Street, PA 19107, USA
    Breast Cancer Res 11:R58. 2009
    ....
  16. doi request reprint OLGA staging for gastritis: a tutorial
    M Rugge
    Department of Medical Diagnostic Sciences and Special Therapies, Pathology Section, University of Padova, Italy
    Dig Liver Dis 40:650-8. 2008
    ..This tutorial aims to provide unequivocal information on how to consistently apply the OLGA staging system in routine diagnostic histology practice...
  17. doi request reprint Gastric cancer precursors: Pieces of an intriguing story
    M Rugge
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padova, Veneto Institute of Oncology, IOV IRCCS, Via Aristide Gabelli 61, 35121 Padova, Italy
    Dig Liver Dis 40:488-9. 2008
  18. doi request reprint Bronchopulmonary carcinoid: phenotype and long-term outcome in a single-institution series of Italian patients
    Massimo Rugge
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padova, Italy
    Clin Cancer Res 14:149-54. 2008
    ....
  19. pmc Secondary prevention of gastric cancer
    Massimo Rugge
    Universitè degli Studi di Padova, Istituto Oncologico del Veneto IOV IRCCS, Via Aristide Gabelli, 61, 35121, Padova, Italy
    Gut 56:1646-7. 2007
  20. pmc Gastritis staging in clinical practice: the OLGA staging system
    Massimo Rugge
    Anatomia Patologica, Universita degli Studi di Padova, Istituto Oncologico del Veneto IOV IRCCS, Via Aristide Gabelli, 61, 35121 Padova, Italia
    Gut 56:631-6. 2007
    ..Gastritis staging integrates the atrophy score (obtained by biopsy) and the atrophy topography (achieved through directed biopsy mapping)...
  21. doi request reprint Gastritis OLGA-staging and gastric cancer risk: a twelve-year clinico-pathological follow-up study
    M Rugge
    Department of Diagnostic Medical Sciences and Special Therapies, University of Padova, Italy
    Aliment Pharmacol Ther 31:1104-11. 2010
    ..Atrophic gastritis is the cancerization field in which GC develops. The current histological reporting formats for gastritis do not include any (atrophy-based) ranking of GC risk...
  22. doi request reprint Aurora kinase A in Barrett's carcinogenesis
    Massimo Rugge
    Department of Medical Diagnostic Sciences and Special Therapies, Pathology Unit, University of Padova, Padua, Italy
    Hum Pathol 41:1380-6. 2010
    ..The identification of AURKA as a novel molecular target of cancer progression in Barrett's mucosa provides a lead for the development of new therapeutic approaches in Barrett's mucosa patients...
  23. pmc Microsatellite instability and gastric non-invasive neoplasia in a high risk population in Cesena, Italy
    M Rugge
    Department of Oncology and Surgical Sciences, University of Padova, I 35121 Padova, Italy
    J Clin Pathol 58:805-10. 2005
    ..In this retrospective cross sectional study, microsatellite instability (MSI) was analysed in a consecutive series of NiN and NiN related histological alterations from a northern Italian region at high risk for gastric cancer...
  24. ncbi request reprint Review article: what have we learnt from gastric biopsy?
    M Rugge
    Department of Oncological and Surgical Sciences, University of Padova, Padova, Italy
    Aliment Pharmacol Ther 17:68-74. 2003
    ....
  25. pmc The long term outcome of gastric non-invasive neoplasia
    M Rugge
    Department of Oncological and Surgical Sciences, III Cattedra di Anatomia Patologica, Università degli Studi di Padova Azienda Ospedale Padova, Italia
    Gut 52:1111-6. 2003
    ..This prospective long term follow up study investigates the clinicopathological behaviour of non-invasive gastric neoplasia (and related lesions), focusing on the cancer risk associated with each different histological phenotype...
  26. doi request reprint Operative Link for Gastritis Assessment gastritis staging incorporates intestinal metaplasia subtyping
    Massimo Rugge
    Surgical Pathology and Cytopathology Unit, Department of Diagnostic Medical Sciences and Special Therapies, University of Padova, Italy
    Hum Pathol 42:1539-44. 2011
    ..001) and H pylori status (Fisher exact, P < .001). Operative Link for Gastritis Assessment staging incorporates the prognostic message obtainable from histochemical gastric mucin subtyping...
  27. doi request reprint Gastritis: the histology report
    Massimo Rugge
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padova, Padova, Italy
    Dig Liver Dis 43:S373-84. 2011
    ..The aim of this tutorial is to provide unequivocal information on how to standardize histology reports on gastritis in diagnostic practice...
  28. pmc Operative link for gastritis assessment vs operative link on intestinal metaplasia assessment
    Massimo Rugge
    Surgical Pathology and Cytopathology Unit, Department of Diagnostic Medical Sciences and Special Therapies, University of Padova, 35100 Padova, Italy
    World J Gastroenterol 17:4596-601. 2011
    ..To compare the reliability of gastritis staging systems in ranking gastritis-associated cancer risk in a large series of consecutive patients...
  29. pmc The phenotype of gastric mucosa coexisting with Barrett's oesophagus
    M Rugge
    Department of Oncological and Surgical Sciences, Cattedra di Istochimica e Immunoistochimica Patologica, ULSS 15 del Veneto, Italia
    J Clin Pathol 54:456-60. 2001
    ..No systematic study has investigated the phenotype of the gastric mucosa coexisting with Barrett's oesophagus. This study was designed to identify the phenotype of gastric mucosa associated with Barrett's oesophagus...
  30. ncbi request reprint p53 alterations but no human papillomavirus infection in preinvasive and advanced squamous esophageal cancer in Italy
    M Rugge
    Cattedra di Istochimica and Immunoistochimica Patologica, University of Padova, Italy
    Cancer Epidemiol Biomarkers Prev 6:171-6. 1997
    ....
  31. ncbi request reprint Squamous cell carcinoma antigen in human liver carcinogenesis
    M Guido
    Department of Diagnostic Medical Sciences and Special Therapies, Universitè degli Studi di Padova, Italy
    J Clin Pathol 61:445-7. 2008
    ..Squamous cell carcinoma antigen (SCCA) is a serine protease inhibitor that can be overexpressed in hepatocellular carcinoma (HCC) at both molecular and protein level, but no data are available on its expression in pre-malignant stages...
  32. doi request reprint Proximal colon cancer in patients aged 51-60 years of age should be tested for microsatellites instability. A comment on the Revised Bethesda Guidelines
    E Urso
    Clinica Chirurgica II, University of Padova, Via Giustiniani 2, Padua, Italy
    Int J Colorectal Dis 23:801-6. 2008
    ..The aim of the study was to evaluate whether the risk of high MSI (MSI-H) is greater in proximal colon cancer of patients 51-60 years old than in early-onset rectal cancer...
  33. pmc Indefinite for non-invasive neoplasia lesions in gastric intestinal metaplasia: the immunophenotype
    Mauro Cassaro
    Department of Diagnostic Medicine and Special Therapies, University of Padova, II Pathology Unit, Padova, Italy
    J Clin Pathol 60:615-21. 2007
    ....
  34. doi request reprint Programmed cell death 4 nuclear loss and miR-21 or activated Akt overexpression in esophageal squamous cell carcinogenesis
    M Fassan
    Department of Medical Diagnostic Sciences and Special Therapies, Surgical Pathology and Cytopathology Unit, University of Padova, Italy
    Dis Esophagus 25:263-8. 2012
    ..PDCD4 down-regulation, as assessed by immunohistochemistry, is a reliable biomarker of early-stage squamous cell esophageal neoplasia, providing additional information in the histological assessment of these lesions...
  35. doi request reprint Clinical and molecular detection of inherited colorectal cancers in northeast Italy: a first prospective study of incidence of Lynch syndrome and MUTYH-related colorectal cancer in Italy
    E Urso
    Clinica Chirurgica 2nd, Dipartimento Scienze Chirurgiche, Oncologiche e Gastroenterologiche, University of Padova, Padua, Italy
    Tumour Biol 33:857-64. 2012
    ..3% and of MSI-H phenotype was 12%. MLH1 methylation and BRAF mutation can exclude 70% of MSI-H cases from gene sequencing...
  36. ncbi request reprint Hepatitis C virus: from oxygen free radicals to hepatocellular carcinoma
    F Farinati
    Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Sezione di Gastroenterologia, Policlinico Universitario, Universita di Padova, Padova, Italy
    J Viral Hepat 14:821-9. 2007
    ....
  37. ncbi request reprint Gastric mucosal atrophy: interobserver consistency using new criteria for classification and grading
    M Rugge
    Department of Oncology and Surgical Sciences, University of Padova, Italy
    Aliment Pharmacol Ther 16:1249-59. 2002
    ....
  38. ncbi request reprint Programmed cell death 4 protein in esophageal cancer
    Matteo Fassan
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padova, Padova PD, I 35100, Italy
    Oncol Rep 24:135-9. 2010
    ....
  39. ncbi request reprint Helicobacter pylori infection in children and adults: a single pathogen but a different pathology
    Nicoletta Gallo
    Department of Laboratory Medicine, University of Padova, Italy
    Helicobacter 8:21-8. 2003
    ..The aims of this retrospective study were to ascertain in large series of children and adults: the relationship of the infecting strain to gastric mucosal lesions; and the relationship of the infecting strain to its duodenal localization...
  40. doi request reprint OLGA gastritis staging in young adults and country-specific gastric cancer risk
    Massimo Rugge
    Department of Medical Diagnostic Sciences and Special Therapies II Pathology Unit, University of Padova, Italy
    Int J Surg Pathol 16:150-4. 2008
    ..In populations at different cancer risk, the gastritis OLGA stage mirrored the gastric cancer incidence. Gastritis staging identifies a subgroup of higher-risk patients...
  41. doi request reprint Prediction of rectal lymph node metastasis by pelvic computed tomography measurement
    F Pomerri
    Department of Diagnostic Sciences and Special Therapies, Istituto Oncologico Veneto, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS, University of Padua, Padua, Italy
    Eur J Surg Oncol 35:168-73. 2009
    ..g. radical resection vs. local excision). The aim of this study was to determine the best lymph node size cut-off at computed tomography (CT) to predict nodal metastasis in rectal cancer patients with and without preoperative CRT...
  42. pmc High prevalence of isolated tumour cells in regional lymph nodes from pN0 colorectal cancer
    C Mescoli
    Department of Diagnostic Sciences and Special Therapies, Pathology Unit, Istituto Oncologico Veneto IRCCS, Universita degli Studi di Padova, Padova, Italy
    J Clin Pathol 59:870-4. 2006
    ..pN0 early-relapsing CRC can be explained by lymph node-ITC...
  43. ncbi request reprint Pericentriolar material analyses in normal esophageal mucosa, Barrett's metaplasia and adenocarcinoma
    Daniela Segat
    Proliferation Unit, Department of Biology, University of Padova, Italy
    Histol Histopathol 25:551-60. 2010
    ..Extending our observations in a prospective study might help in the development of new prevention protocols for adenocarcinoma patients...
  44. pmc The p53 gene in patients under the age of 40 with gastric cancer: mutation rates are low but are associated with a cardiac location
    M Rugge
    Department of Oncology and Surgical Sciences, University of Padova, ULSS15 Regione Veneto, Italy
    Mol Pathol 53:207-10. 2000
    ..Determining both the frequency and the spectrum of p53 gene mutation in young patients with gastric cancer might provide clues to the host related genetic mechanism(s) in gastric carcinogenesis...
  45. ncbi request reprint Helicobacter pylori virulence genes and host IL-1RN and IL-1beta genes interplay in favouring the development of peptic ulcer and intestinal metaplasia
    C F Zambon
    Department of Laboratory Medicine, University of Padova, Italy
    Cytokine 18:242-51. 2002
    ..An interplay between bacterial virulence factors and cytokines genotypes, is probably the main route causing H. pylori infection to lead to benign mild disease, benign severe disease or preneoplastic lesions...
  46. ncbi request reprint Staging and grading of chronic gastritis
    Massimo Rugge
    Department of Oncological and Surgical Sciences, University of Padova, Italy
    Hum Pathol 36:228-33. 2005
    ..This system could offer gastroenterologists a more immediate perception of the overall condition of the gastric mucosa while also providing useful information about gastric cancer risk...
  47. ncbi request reprint Non-invasive diagnosis of Helicobacter pylori infection: simplified 13C-urea breath test, stool antigen testing, or DNA PCR in human feces in a clinical laboratory setting?
    Carlo Federico Zambon
    Department of Medical and Surgical Sciences, University of Padova, Italy
    Clin Biochem 37:261-7. 2004
    ..2) To ascertain whether a simplified UBT (breath collection time = 10 min) is as reliable as the standard assay (30 min)...
  48. ncbi request reprint The potential of restaging in the prediction of pathologic response after preoperative chemoradiotherapy for rectal cancer
    Isacco Maretto
    Department of Oncological and Surgical Sciences, Clinica Chirurgica II, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy
    Ann Surg Oncol 14:455-61. 2007
    ....
  49. ncbi request reprint Fibrosis in chronic hepatitis C acquired in infancy: is it only a matter of time?
    Maria Guido
    Dipartimento di Scienze Oncologiche and Chirurgiche, Universita degli Studi di Padova, Azienda Ospedale Padova, Padova, Italy
    Am J Gastroenterol 98:660-3. 2003
    ..The natural history of chronic hepatitis C acquired in infancy is not well understood. The progression of fibrosis was analyzed in untreated children with chronic hepatitis C virus infection and no other hepatotoxic cofactors...
  50. ncbi request reprint Nuclear DNA content and pathology in radically treated pancreatic carcinoma. The prognostic significance of DNA ploidy, histology and nuclear grade
    M Rugge
    Cattedra di Istochimica and Immunoistochimica Patologica, Università di Padova ULSS 15 Veneto, Italy
    Cancer 77:459-66. 1996
    ..Histopathology and DNA ploidy were each correlated with survival in radically treated PC to ascertain the hierarchy of their prognostic significance...
  51. doi request reprint Helicobacter pylori, inflammation, oxidative damage and gastric cancer: a morphological, biological and molecular pathway
    Fabio Farinati
    Departments of Surgical and Gastroenterological Sciences, Padua University, Padua, Italy
    Eur J Cancer Prev 17:195-200. 2008
    ..The growing body of evidence of the regression of precancerous changes and the high prevalence of superficial gastric carcinoma demonstrated in long-term follow-up studies on NiN make this approach mandatory...
  52. ncbi request reprint Differential effects of Helicobacter pylori eradication on oxidative DNA damage at the gastroesophageal junction and at the gastric antrum
    Fabio Farinati
    Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Sezione di Gastroenterologia, Policlinico Universitario, Via Giustiniani 2, 35128 Padova, Italy
    Cancer Epidemiol Biomarkers Prev 13:1722-8. 2004
    ..This prospective study evaluates DNA oxidative damage in biopsy samples obtained from both the antrum and the gastroesophageal junction (GEJ) before and after H. pylori eradication...
  53. doi request reprint Oxidative DNA damage in gastric cancer: CagA status and OGG1 gene polymorphism
    Fabio Farinati
    Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Universita di Padova, Padova, Italy
    Int J Cancer 123:51-5. 2008
    ..OGG1 1245C-->G polymorphism was common in both GC and IMA, but very rare in controls, and correlated more closely with 8-OHdG levels than do H. pylori infection or cagA status...
  54. ncbi request reprint [Fever of unknown origin and monoclonal gammapathy with unclear significance. Report of 2 cases with different pathology and clinical course]
    Giuseppe Realdi
    Dipartimento di Scienze Mediche e Chirurgiche, Universita degli Studi di Padova
    Ann Ital Med Int 19:214-29. 2004
  55. ncbi request reprint 5-fluorouracil and weekly oxaliplatin combined with radiotherapy for locally advanced rectal cancer: surgical complications and long-term results
    Salvatore Pucciarelli
    Clinica Chirurgica II, Dipartimento di Scienze Oncologiche e Chirurgiche, Policlinico, Padova, Italy
    Arch Med Res 37:860-5. 2006
    ..We undertook this study to evaluate early surgical complications and long-term results after preoperative radiotherapy and chemotherapy (RCT) using 5-fluorouracil (5-FU) and oxaliplatin (OXA) for rectal cancer...
  56. doi request reprint Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Gastroenterology 135:91-9. 2008
    ..We assessed the association of new and established cagA and vacA polymorphisms with disease...
  57. doi request reprint Prospective assessment of imaging after preoperative chemoradiotherapy for rectal cancer
    Fabio Pomerri
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua, Padua, Italy
    Surgery 149:56-64. 2011
    ....
  58. doi request reprint Hepatic spleen nodules (HSN)
    Claudia Mescoli
    Department of Pathology, University of Padova, Padova, Italy
    Scand J Gastroenterol 45:628-32. 2010
    ..Although they are rare, hepatic spleen nodules should always be included in the diagnostic spectrum of nodular liver lesions because of their impact on treatment decisions...
  59. doi request reprint Prediction of lymph node status in superficial esophageal carcinoma
    Ermanno Ancona
    Istituto Oncologico Veneto IOV IRCCS University of Padova School of Medicine, Padova, Italy
    Ann Surg Oncol 15:3278-88. 2008
    ..Real chances for cure depend on both early recognition and early treatment. The ability to predict lymph node involvement allows early curative treatment with less invasive approaches...
  60. doi request reprint Donor livers with steatosis are safe to use in hepatitis C virus-positive recipients
    Patrizia Burra
    Gastroenterology Section, Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
    Liver Transpl 15:619-28. 2009
    ..Steatotic grafts do not seem to exacerbate the progression of fibrosis in HCV+ recipients, nor do they seem to negatively affect 3-year patient survival...
  61. doi request reprint Trefoil peptides, E-cadherin, and beta-catenin expression in sporadic fundic gland polyps: further evidence toward the benign nature of these lesions
    Anna D'Odorico
    Department of Surgical and Gastroenterological Sciences, University of Padua, Padova, Italy
    Appl Immunohistochem Mol Morphol 17:431-7. 2009
    ..In conclusion all the factors considered were normally expressed in FGP and this, especially considered against the findings in IM-gastritis, supports the benign nature of FGP...
  62. doi request reprint Hepatitis C virus reinfection in liver transplant patients: evaluation of liver damage progression with echo-color Doppler
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    Liver Transpl 14:616-24. 2008
    ..In conclusion, the information obtainable from splanchnic Doppler parameters can be used to monitor the progression of liver fibrosis in transplant patients with HCV reinfection...
  63. pmc Liver transplantation for the treatment of moderately or well-differentiated hepatocellular carcinoma
    Umberto Cillo
    Clinica Chirurgica I, Dipartimento di Scienze Chirurgiche e Gastroenterlogiche, Italy
    Ann Surg 239:150-9. 2004
    ..To determine the long-term results of liver transplantation for well- or moderately differentiated hepatocellular carcinoma (HCC)...
  64. ncbi request reprint Acute liver rejection: accuracy and predictive values of doppler US measurements--initial experience
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, Institute of General Surgery, Clinica Medica 5, Policlinico Universitario, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
    Radiology 235:651-8. 2005
    ....
  65. ncbi request reprint Non-invasive neoplasia of the stomach
    Massimo Rugge
    Department of Oncological and Surgical Sciences Pathology Unit, Universita degli Studi di Padova, Italy
    Eur J Gastroenterol Hepatol 17:1191-6. 2005
    ..The molecular profile of NiN is summarized and the spectrum of the options in the clinical management of gastric NiN are reported...
  66. ncbi request reprint Features predicting unresectability in hepatoblastoma
    Lorenzo D'Antiga
    Department of Pediatrics, University of Padova, Padova, Italy
    Cancer 110:1050-8. 2007
    ..The authors sought to identify presenting features that would predict unresectability in patients with HB and to provide suggestions for early referral and listing for OLT...
  67. ncbi request reprint Molecular characteristics in papillary thyroid cancers (PTCs) with no 131I uptake
    Caterina Mian
    Endocrinology Unit, Department of Medical and Surgical Sciences, University of Padua, Italy
    Clin Endocrinol (Oxf) 68:108-16. 2008
    ..Papillary thyroid cancers (PTCs) with no iodine uptake have an aggressive behaviour and a poor prognosis. The aim of our study was to characterize, at molecular level, a subset of PTC with no 131 iodine ((131)I) uptake...
  68. ncbi request reprint Different hemodynamic patterns of alcoholic and viral endstage cirrhosis: analysis of explanted liver weight, degree of fibrosis and splanchnic Doppler parameters
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, University of Padua, Italy
    Scand J Gastroenterol 42:256-62. 2007
    ..The objective of this study was to investigate the role of the etiology of liver disease on the relationship between liver blood flow and liver pathology in endstage cirrhosis...
  69. ncbi request reprint Liver biopsy sampling in chronic viral hepatitis
    Maria Guido
    Universita degli Studi di Padova, Azienda Ospedale, Padova, Italy
    Semin Liver Dis 24:89-97. 2004
    ..Integrating earlier experience with more recently produced data indicates that a biopsy sample 2 cm or more in length containing at least 11 complete portal tracts should be reliable for grading and staging chronic viral hepatitis...
  70. pmc Oxidative damage, pro-inflammatory cytokines, TGF-alpha and c-myc in chronic HCV-related hepatitis and cirrhosis
    Fabio Farinati
    Department of Surgical and Gastroenterological Sciences, University of Padua, Italy
    World J Gastroenterol 12:2065-9. 2006
    ..To assess whether a correlation exists between oxidative DNA damage occurring in chronic HCV-related hepatitis and expression levels of pro-inflammatory cytokines, TGF-alpha and c-myc...
  71. ncbi request reprint Pro- and anti-inflammatory cytokines gene polymorphisms and Helicobacter pylori infection: interactions influence outcome
    Carlo F Zambon
    Department of Medical and Surgical Sciences, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
    Cytokine 29:141-52. 2005
    ..In conclusion, among host genetic factors contributing to H. pylori disease outcome, IFN-G +874 AA genotype favors cagA positive infections, TNF-A -857 TT duodenal ulcer while IL-10 -819 TT intestinal metaplasia and NCGC...
  72. doi request reprint Microwave thermal ablation for hepatocarcinoma: six liver transplantation cases
    G Zanus
    General Surgery and Organ Transplantation, Hepatobiliary Surgery and Liver Transplant Unit, Azienda Università di Padova, Padova, Italy
    Transplant Proc 43:1091-4. 2011
    ..In conclusion, a MWA seemed to be a safe novel approach to treat HCC and could serve as a "bridge" to OLT and down-staging for patients with HCC...
  73. ncbi request reprint The Veneto Region's Barrett's Oesophagus Registry: aims, methods, preliminary results
    G Zaninotto
    Department of General Surgery and Organ Transplantation, University of Padova, Padova, Italy
    Dig Liver Dis 39:18-25. 2007
    ..A Barrett's Oeosphagus Registry has been therefore established in the Veneto Region and neighbouring provinces...
  74. ncbi request reprint Micronuclei and broken eggs in human liver carcinogenesis
    Maria Guido
    Department of Diagnostic Medical Sciences and Special Therapies, Pathology Unit, Universita degli Studi di Padova, Italy
    Anticancer Res 28:2507-11. 2008
    ..MNi/BE formation may result in activation of the p53-mediated cell cycle checkpoint...
  75. ncbi request reprint Liver steatosis in children with chronic hepatitis C
    Maria Guido
    Department of Oncological and Surgical Sciences Pathology Section, University of Padova, Azienda Ospedaliera, Padova, Italy
    Am J Gastroenterol 101:2611-5. 2006
    ....
  76. doi request reprint IL-4 -588C>T polymorphism and IL-4 receptor alpha [Ex5+14A>G; Ex11+828A>G] haplotype concur in selecting H. pylori cagA subtype infections
    Carlo Federico Zambon
    Department of Medical and Surgical Sciences, University of Padova, Italy
    Clin Chim Acta 389:139-45. 2008
    ..pylori virulence genes or H. pylori associated diseases...
  77. ncbi request reprint Determining therapeutic approaches in the elderly with rectal cancer
    Lara Maria Pasetto
    Medical Oncology 2nd, Istituto Oncologico Veneto, Padova, Italy
    Drugs Aging 24:781-90. 2007
    ..To evaluate the toxicity and feasibility of pelvic radiotherapy (RT) and/or surgery in elderly patients with locally advanced low-lying rectal cancer...
  78. ncbi request reprint Primary squamous cell carcinoma of the thyroid: immunohistochemical profile and literature review
    Matteo Fassan
    Pathology Unit, Department of Medical Diagnostic Sciences and Special Therapies, University of Padua, Padua, Italy
    Tumori 93:518-21. 2007
    ..Squamous cell carcinoma accounts for 1% of primary thyroid malignancies and is characterized by a rapidly unfavorable outcome...
  79. ncbi request reprint Spontaneous regression of hepatitis B virus-associated cirrhosis developed in childhood
    F Bortolotti
    Department of Clinical and Experimental Medicine, Clinica Medica 5, University of Padua, Policlinico, Via Giustiniani 2, Italy
    Dig Liver Dis 37:964-7. 2005
    ..Subsidence of virus replication and of necro-inflammatory process and the efficiency of liver regeneration and repair might contribute to this favourable outcome...
  80. pmc Histology predicts cirrhotic evolution of post transplant hepatitis C
    M Guido
    Department of Oncology and Surgical Sciences, University of Padova, Italia
    Gut 50:697-700. 2002
    ..Hepatitis C recurring after orthotopic liver transplantation varies in severity and some patients rapidly develop fully established liver cirrhosis. Neither clinical nor biological markers of such rapid cirrhotic evolution are available...
  81. doi request reprint Bronchial carcinoid tumours in children: surgical treatment and outcome in a single institution
    G Rizzardi
    Thoracic Surgery, Cardio vascular thoracic Science, Padova, Italy
    Eur J Pediatr Surg 19:228-31. 2009
    ..Although rare, they represent the most common primary bronchial tumours in childhood. The aim of our study was to analyse the long-term survival and surgical treatment outcome in our young patients operated for carcinoid tumour...
  82. ncbi request reprint Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms
    Carlo Federico Zambon
    Departments of Medical and Surgical Sciences, Laboratory Medicine, Oncological and Surgical Sciences, Gastroenterology, and Pathology, University of Padova, Padova, Italy
    Gastroenterology 126:382-4. 2004
  83. ncbi request reprint Rectal cancer neoadjuvant treatment in elderly patients
    Lara Maria Pasetto
    Medical Oncology Department, Istituto Oncologico Veneto, Padova, Italy
    Anticancer Res 26:3913-23. 2006
    ..A secondary endpoint was to identify any specific comorbidity that affected either effectiveness or morbidity of treatment...
  84. ncbi request reprint Galectin-3 cytotest in thyroid follicular neoplasia: a prospective, monoinstitutional study
    Gianmaria Pennelli
    Veneto Institute of Oncology, Department of Medical Diagnostic Sciences and Special Therapies, University of Padova, Padova, Italy
    Acta Cytol 53:533-9. 2009
    ..To analyze the utility of galectin-3 (Gal3) immunohistochemistry (IHC) on preoperatively obtained fine needle aspiration biopsy (FNAB) in identifying the subgroup of follicular neoplasia (FN) patients who were candidates for thyroidectomy...
  85. ncbi request reprint Rectal cancer adjuvant chemotherapy: when is more useful?
    Lara Maria Pasetto
    Oncologia Medical 2, Istituto Oncologico Veneto, IRCCS, Padova, Italy
    Anticancer Res 28:1805-12. 2008
    ..A secondary end-point was to identify the possible influence of clinical TNM (cTNM) or pathological TNM (pTNM) on TTP and overall survival (OS)...
  86. pmc Dynamic changes of live/apoptotic circulating tumour cells as predictive marker of response to sunitinib in metastatic renal cancer
    E Rossi
    Department of Surgery, Oncology and Gastroenterology, Oncology Section, University of Padova, Italy
    Br J Cancer 107:1286-94. 2012
    ..The test was first applied here to mRCC...
  87. ncbi request reprint Effects of interferon plus ribavirin treatment on NF-kappaB, TGF-beta1, and metalloproteinase activity in chronic hepatitis C
    Maria Guido
    Section of Anatomic Pathology, Department of Oncological and Surgical Science, University of Padova, Italy
    Mod Pathol 19:1047-54. 2006
    ..Combination therapy with interferon and ribavirin affects the tissue expression of TGF-beta-1 and NF-kappaB and favors metalloproteinase activity, and may thereby modulate hepatic fibrogenetic events...
  88. ncbi request reprint Neoadjuvant chemoradiotherapy with 5-fluorouracil by bolus
    Lara Maria Pasetto
    Istituto Oncologico Veneto, IRCCS, Medical Oncology 2, Padova, Italy
    Anticancer Res 28:4095-100. 2008
    ..Since the presence of cardiomiopathy may contraindicate c.i. of 5-FU, an alternative regimen of 5-FU CT-RT was prospectively studied in these patients...
  89. doi request reprint BRAF in primary and recurrent papillary thyroid cancers: the relationship with (131)I and 2-[(18)F]fluoro-2-deoxy-D-glucose uptake ability
    Susi Barollo
    Istituto Oncologico Veneto IRCCS, Padova, Italy
    Eur J Endocrinol 163:659-63. 2010
    ..In a previous report, we showed that recurrent PTC with no radioiodine ((131)I) uptake are frequently associated with BRAF mutations, a low expression of thyroid-related genes and a high expression of glucose type-1 transporter gene...
  90. doi request reprint Restorative proctocolectomy for inflammatory bowel disease: the Padova prognostic score for colitis in predicting long-term outcome and quality of life
    Marco Scarpa
    Department of Surgery, Veneto Oncological Institute IOV IRCCS, Padua, Italy
    Int J Colorectal Dis 24:1049-57. 2009
    ....
  91. doi request reprint Antibodies against synthetic deamidated gliadin peptides for celiac disease diagnosis and follow-up in children
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Italy
    Clin Chem 55:150-7. 2009
    ..AGA IgA II and AGA IgG II have recently been suggested as reliable tools for celiac disease (CD) diagnosis. We compared their utility for diagnosis and monitoring CD in children with that of tTG IgA, an established CD marker...
  92. pmc Does Helicobacter pylori infection eradication modify peptic ulcer prevalence? A 10 years' endoscopical survey
    Giorgio Nervi
    Dipartimento di Scienze Cliniche, Sezione di Gastroenterologia, Azienda Ospedaliera Universitaria di Parma, V Gramsci 14, 43100 Parma, Italy
    World J Gastroenterol 12:2398-401. 2006
    ..To compare peptic ulcer prevalence in patients referred for upper gastrointestinal endoscopy in two Italian hospitals in pre-Helicobacter era and ten years after the progressive diffusion of eradication therapy...
  93. ncbi request reprint Natural course of functional dyspepsia after Helicobacter pylori eradication: a seven-year survey
    Francesco Di Mario
    University of Parma, Parma, Italy
    Dig Dis Sci 50:2286-95. 2005
    ..FD symptoms slightly improve after Hp eradication over a long period of time but a large percentage of these improved patients may experience FD symptoms again, even after some years of well-being after Hp eradication...
  94. pmc Assessing risks for gastric cancer: new tools for pathologists
    Robert M Genta
    Pathology and Laboratory Service 113, VA North Texas Health Care System, 4500 S Lancaster Road, Dallas, TX 75216, USA
    World J Gastroenterol 12:5622-7. 2006
    ..Such an integrated report could facilitate clinicians' approach to the management of patients with gastric conditions...
  95. ncbi request reprint Rabeprazole in a one-week eradication therapy of Helicobacter pylori: comparison of different dosages
    Francesco Di Mario
    Department of Clinical Science, University of Parma, Parma, Italy
    J Gastroenterol Hepatol 18:783-6. 2003
    ..We report the efficacy and tolerability of rabeprazole in different dosages in association with clarithromycin (C)and tinidazole (T) in H. pylori eradication...
  96. ncbi request reprint Serological markers for gastric atrophy in asymptomatic patients infected with Helicobacter pylori
    Chiara Ricci
    Department of Internal Medicine and Gastroenterology, University of Bologna, University Hospital S Orsola Malpighi, Bologna, Italy
    Am J Gastroenterol 99:1910-5. 2004
    ..pylori) infection. This blinded, controlled study was designed to determine if serum gastrin and pepsinogens were reliable markers of atrophy in asymptomatic patients...
  97. ncbi request reprint Asthma-like syndrome in a teenager
    Angelo Barbato
    Pediatr Allergy Immunol 14:412-3. 2003
  98. ncbi request reprint Usefulness of serum pepsinogens in Helicobacter pylori chronic gastritis: relationship with inflammation, activity, and density of the bacterium
    Francesco Di Mario
    Chair of Gastroenterology, Department of Clinical Sciences, University of Parma, Via Gramsci 14, 43100 Parma, Italy
    Dig Dis Sci 51:1791-5. 2006
    ..33, P < .001) and intestinal metaplasia (r = -0.37, P < .001) in the corpus. sPGII levels could be considered as markers of gastric inflammation all over in the stomach. sPGI levels are inversely related to atrophic body gastritis...
  99. ncbi request reprint Primary rectal carcinoma in patients with stage IV resectable disease at diagnosis
    Lara Maria Pasetto
    Medical Oncology Department, Via Gattamelata 64, Istituto Oncologico Veneto, 35128 Padova, Italy
    Anticancer Res 27:1079-85. 2007
    ..The purpose of this study was to review the feasibility and outcome of multimodality treatment of rectal cancer patients metastatic at diagnosis...
  100. ncbi request reprint Early epigastric pain after PPI administration: exacerbation of Helicobacter pylori corpus gastritis?
    Francesco Di Mario
    Helicobacter 9:92-4. 2004