Genomes and Genes
Affiliation: University of Padova
Publications114 found, 100 shown here
- Helicobacter pylori CagA status, mucosal oxidative damage and gastritis phenotype: a potential pathway to cancer?Fabio Farinati
Dipartimento di Scienze Chirurgiche e Gastroenterologiche Sezione di Gastroenterologia, Universita degli Studi di Padova, Italy
Helicobacter 8:227-34. 2003..Oxidative DNA damage is associated with Helicobacter pylori infection, atrophy and intestinal metaplasia. H. pylori-cagA-positive strains are associated with the highest risk of gastric cancer...
- Gastric Cancer Risk in Patients with Helicobacter pylori Infection and Following Its EradicationMassimo Rugge
Surgical Pathology and Cytopathology Unit, Department of Medicine DIMED, University of Padova, Via Aristide Gabelli, 61, Padova 35121, Italy Electronic address
Gastroenterol Clin North Am 44:609-24. 2015..The reversibility of inflammatory lesions has been supported by undeniable evidence; the regression of mucosal atrophy/metaplasia has also been confirmed by several recent histologic studies. ..
- Individual risk stratification of gastric cancer: evolving concepts and their impact on clinical practiceMassimo Rugge
Department of Medicine, DIMED, Surgical Pathology and Cytopathology Unit, University of Padua, 35100 Padua, Italy Electronic address
Best Pract Res Clin Gastroenterol 28:1043-53. 2014..Multidisciplinary diagnostic approaches integrating endoscopy, serology, histology and molecular profiling currently appears as the most appropriate approach for patients' stratification into different GC risk classes. ..
- Impact of microRNAs on regulatory networks and pathways in human colorectal carcinogenesis and development of metastasisSilvia Pizzini
Oncology and Immunology Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
BMC Genomics 14:589. 2013....
- MicroRNA Expression Profiling in the Histological Subtypes of Barrett's MetaplasiaMatteo Fassan
1 Department of Medicine DIMED, Surgical Pathology and Cytopathology Unit, University of Padua, Padua, Italy 2 Department of Surgical, Oncological and Gastroenterological Sciences DiSCOG, General Oncology Unit, University of Padua, Padua, Italy
Clin Transl Gastroenterol 4:e34. 2013..This study investigates miRNA expression in the histological spectrum of esophageal columnar metaplastic changes, specifically addressing the biological profile of GM vs. IM...
- Pancreatic mucinous cystic tumor in Turner syndrome: How a tumor bends to a genetic diseaseMarco Pizzi
Department of Medicine DIMED, Surgical Pathology and Cytopathology Unit, University of Padova, Italy
Int J Surg Case Rep 4:1028-31. 2013..On histology, MCNs concurrently show an epithelial mucosecreting component with ovarian-type stromal cells...
- Programmed cell death 4 (PDCD4) expression during multistep Barrett's carcinogenesisMatteo Fassan
Department of Medical Diagnostic Sciences, University of Padova, Padova, Italy
J Clin Pathol 63:692-6. 2010..To test the contribution of programmed cell death 4 (PDCD4) tumour suppressor gene in Barrett's carcinogenesis...
- Helicobacter pylori Infection, Intestinal Metaplasia, and Gastric Cancer Risk in Eastern SiberiaVladislav Vladimirovich Tsukanov
State Scientific Medical Research Institute for Northern Problems of Siberian Division of Russian Academy of Medical Sciences, Krasnoyarsk, Russia Khakass State University, Abakan, Russia
Helicobacter 16:107-12. 2011..The incidence of gastric cancer (GC) is extremely high in Russia and eastern Siberia, where information on the epidemiology of Helicobacter pylori infection is fragmentary...
- Oxidative DNA damage correlates with cell immortalization and mir-92 expression in hepatocellular carcinomaRomilda Cardin
Department of Surgery, Oncology and Gastroenterology, Section of Gastroenterology, University of Padova, Via Giustiniani 2, Padova 35128, Italy
BMC Cancer 12:177. 2012....
- Precancerous lesions in the stomach: from biology to clinical patient managementMassimo Rugge
Department of Medicine DIMED, Surgical Pathology and Cytopathology Unit, University of Padova, Padova, Italy
Best Pract Res Clin Gastroenterol 27:205-23. 2013..This paper addresses the epidemiology, pathology, molecular profiling, and clinical management of advanced precancerous gastric lesions. ..
- MicroRNA dysregulation in esophageal neoplasia: the biological rationale for novel therapeutic optionsMatteo Fassan
Department of Medicine DIMED, Surgical Pathology and Cytopathology Unit, University of Padua, Padua PD, Italy
Curr Pharm Des 19:1236-41. 2013..In addition to these valuable features, miRNAs have been proposed as innovative therapeutics per se and as plausible biological targets in new treatment strategies...
- Autoimmune gastritis: histology phenotype and OLGA stagingM Rugge
Department of Medicine, University of Padua, PD, Italy
Aliment Pharmacol Ther 35:1460-6. 2012..Among Western populations, the declining incidence of Helicobacter pylori infection coincides with a growing clinical impact of autoimmune gastritis...
- Isolated tumor cells in regional lymph nodes as relapse predictors in stage I and II colorectal cancerClaudia Mescoli
Universita degli Studi di Padova, Padova, Italy
J Clin Oncol 30:965-71. 2012..Approximately 15% to 20% of patients without nodal metastases (pN0) develop recurrent disease. In this study, we tested the prognostic significance of isolated tumor cells (ITCs) in LNs of patients with pN0 CRC (stages I and II)...
- CDX2 hox gene product in a rat model of esophageal cancerGiuseppe Ingravallo
Department of Medical Diagnostic Sciences and Special Therapies, Pathology Unit, University of Padova, Padova, Italy
J Exp Clin Cancer Res 28:108. 2009..Experimental models of longstanding esophageal reflux of duodenal-gastric contents may provide important information on the biological sequence of the Barrett's oncogenesis...
- MicroRNA expression profiling of male breast cancerMatteo Fassan
Department of Urology, Thomas Jefferson University Kimmel Cancer Center, 1112 College Building, 1025 Walnut Street, PA 19107, USA
Breast Cancer Res 11:R58. 2009....
- OLGA staging for gastritis: a tutorialM Rugge
Department of Medical Diagnostic Sciences and Special Therapies, Pathology Section, University of Padova, Italy
Dig Liver Dis 40:650-8. 2008..This tutorial aims to provide unequivocal information on how to consistently apply the OLGA staging system in routine diagnostic histology practice...
- Gastric cancer precursors: Pieces of an intriguing storyM Rugge
Department of Medical Diagnostic Sciences and Special Therapies, University of Padova, Veneto Institute of Oncology, IOV IRCCS, Via Aristide Gabelli 61, 35121 Padova, Italy
Dig Liver Dis 40:488-9. 2008
- Bronchopulmonary carcinoid: phenotype and long-term outcome in a single-institution series of Italian patientsMassimo Rugge
Department of Medical Diagnostic Sciences and Special Therapies, University of Padova, Italy
Clin Cancer Res 14:149-54. 2008....
- Secondary prevention of gastric cancerMassimo Rugge
Universitè degli Studi di Padova, Istituto Oncologico del Veneto IOV IRCCS, Via Aristide Gabelli, 61, 35121, Padova, Italy
Gut 56:1646-7. 2007
- Gastritis staging in clinical practice: the OLGA staging systemMassimo Rugge
Anatomia Patologica, Universita degli Studi di Padova, Istituto Oncologico del Veneto IOV IRCCS, Via Aristide Gabelli, 61, 35121 Padova, Italia
Gut 56:631-6. 2007..Gastritis staging integrates the atrophy score (obtained by biopsy) and the atrophy topography (achieved through directed biopsy mapping)...
- Gastritis OLGA-staging and gastric cancer risk: a twelve-year clinico-pathological follow-up studyM Rugge
Department of Diagnostic Medical Sciences and Special Therapies, University of Padova, Italy
Aliment Pharmacol Ther 31:1104-11. 2010..Atrophic gastritis is the cancerization field in which GC develops. The current histological reporting formats for gastritis do not include any (atrophy-based) ranking of GC risk...
- Aurora kinase A in Barrett's carcinogenesisMassimo Rugge
Department of Medical Diagnostic Sciences and Special Therapies, Pathology Unit, University of Padova, Padua, Italy
Hum Pathol 41:1380-6. 2010..The identification of AURKA as a novel molecular target of cancer progression in Barrett's mucosa provides a lead for the development of new therapeutic approaches in Barrett's mucosa patients...
- Microsatellite instability and gastric non-invasive neoplasia in a high risk population in Cesena, ItalyM Rugge
Department of Oncology and Surgical Sciences, University of Padova, I 35121 Padova, Italy
J Clin Pathol 58:805-10. 2005..In this retrospective cross sectional study, microsatellite instability (MSI) was analysed in a consecutive series of NiN and NiN related histological alterations from a northern Italian region at high risk for gastric cancer...
- Review article: what have we learnt from gastric biopsy?M Rugge
Department of Oncological and Surgical Sciences, University of Padova, Padova, Italy
Aliment Pharmacol Ther 17:68-74. 2003....
- The long term outcome of gastric non-invasive neoplasiaM Rugge
Department of Oncological and Surgical Sciences, III Cattedra di Anatomia Patologica, Università degli Studi di Padova Azienda Ospedale Padova, Italia
Gut 52:1111-6. 2003..This prospective long term follow up study investigates the clinicopathological behaviour of non-invasive gastric neoplasia (and related lesions), focusing on the cancer risk associated with each different histological phenotype...
- Operative Link for Gastritis Assessment gastritis staging incorporates intestinal metaplasia subtypingMassimo Rugge
Surgical Pathology and Cytopathology Unit, Department of Diagnostic Medical Sciences and Special Therapies, University of Padova, Italy
Hum Pathol 42:1539-44. 2011..001) and H pylori status (Fisher exact, P < .001). Operative Link for Gastritis Assessment staging incorporates the prognostic message obtainable from histochemical gastric mucin subtyping...
- Gastritis: the histology reportMassimo Rugge
Department of Medical Diagnostic Sciences and Special Therapies, University of Padova, Padova, Italy
Dig Liver Dis 43:S373-84. 2011..The aim of this tutorial is to provide unequivocal information on how to standardize histology reports on gastritis in diagnostic practice...
- Operative link for gastritis assessment vs operative link on intestinal metaplasia assessmentMassimo Rugge
Surgical Pathology and Cytopathology Unit, Department of Diagnostic Medical Sciences and Special Therapies, University of Padova, 35100 Padova, Italy
World J Gastroenterol 17:4596-601. 2011..To compare the reliability of gastritis staging systems in ranking gastritis-associated cancer risk in a large series of consecutive patients...
- The phenotype of gastric mucosa coexisting with Barrett's oesophagusM Rugge
Department of Oncological and Surgical Sciences, Cattedra di Istochimica e Immunoistochimica Patologica, ULSS 15 del Veneto, Italia
J Clin Pathol 54:456-60. 2001..No systematic study has investigated the phenotype of the gastric mucosa coexisting with Barrett's oesophagus. This study was designed to identify the phenotype of gastric mucosa associated with Barrett's oesophagus...
- p53 alterations but no human papillomavirus infection in preinvasive and advanced squamous esophageal cancer in ItalyM Rugge
Cattedra di Istochimica and Immunoistochimica Patologica, University of Padova, Italy
Cancer Epidemiol Biomarkers Prev 6:171-6. 1997....
- Squamous cell carcinoma antigen in human liver carcinogenesisM Guido
Department of Diagnostic Medical Sciences and Special Therapies, Universitè degli Studi di Padova, Italy
J Clin Pathol 61:445-7. 2008..Squamous cell carcinoma antigen (SCCA) is a serine protease inhibitor that can be overexpressed in hepatocellular carcinoma (HCC) at both molecular and protein level, but no data are available on its expression in pre-malignant stages...
- Proximal colon cancer in patients aged 51-60 years of age should be tested for microsatellites instability. A comment on the Revised Bethesda GuidelinesE Urso
Clinica Chirurgica II, University of Padova, Via Giustiniani 2, Padua, Italy
Int J Colorectal Dis 23:801-6. 2008..The aim of the study was to evaluate whether the risk of high MSI (MSI-H) is greater in proximal colon cancer of patients 51-60 years old than in early-onset rectal cancer...
- Indefinite for non-invasive neoplasia lesions in gastric intestinal metaplasia: the immunophenotypeMauro Cassaro
Department of Diagnostic Medicine and Special Therapies, University of Padova, II Pathology Unit, Padova, Italy
J Clin Pathol 60:615-21. 2007....
- Programmed cell death 4 nuclear loss and miR-21 or activated Akt overexpression in esophageal squamous cell carcinogenesisM Fassan
Department of Medical Diagnostic Sciences and Special Therapies, Surgical Pathology and Cytopathology Unit, University of Padova, Italy
Dis Esophagus 25:263-8. 2012..PDCD4 down-regulation, as assessed by immunohistochemistry, is a reliable biomarker of early-stage squamous cell esophageal neoplasia, providing additional information in the histological assessment of these lesions...
- Clinical and molecular detection of inherited colorectal cancers in northeast Italy: a first prospective study of incidence of Lynch syndrome and MUTYH-related colorectal cancer in ItalyE Urso
Clinica Chirurgica 2nd, Dipartimento Scienze Chirurgiche, Oncologiche e Gastroenterologiche, University of Padova, Padua, Italy
Tumour Biol 33:857-64. 2012..3% and of MSI-H phenotype was 12%. MLH1 methylation and BRAF mutation can exclude 70% of MSI-H cases from gene sequencing...
- Hepatitis C virus: from oxygen free radicals to hepatocellular carcinomaF Farinati
Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Sezione di Gastroenterologia, Policlinico Universitario, Universita di Padova, Padova, Italy
J Viral Hepat 14:821-9. 2007....
- Gastric mucosal atrophy: interobserver consistency using new criteria for classification and gradingM Rugge
Department of Oncology and Surgical Sciences, University of Padova, Italy
Aliment Pharmacol Ther 16:1249-59. 2002....
- Programmed cell death 4 protein in esophageal cancerMatteo Fassan
Department of Medical Diagnostic Sciences and Special Therapies, University of Padova, Padova PD, I 35100, Italy
Oncol Rep 24:135-9. 2010....
- Helicobacter pylori infection in children and adults: a single pathogen but a different pathologyNicoletta Gallo
Department of Laboratory Medicine, University of Padova, Italy
Helicobacter 8:21-8. 2003..The aims of this retrospective study were to ascertain in large series of children and adults: the relationship of the infecting strain to gastric mucosal lesions; and the relationship of the infecting strain to its duodenal localization...
- OLGA gastritis staging in young adults and country-specific gastric cancer riskMassimo Rugge
Department of Medical Diagnostic Sciences and Special Therapies II Pathology Unit, University of Padova, Italy
Int J Surg Pathol 16:150-4. 2008..In populations at different cancer risk, the gastritis OLGA stage mirrored the gastric cancer incidence. Gastritis staging identifies a subgroup of higher-risk patients...
- Prediction of rectal lymph node metastasis by pelvic computed tomography measurementF Pomerri
Department of Diagnostic Sciences and Special Therapies, Istituto Oncologico Veneto, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS, University of Padua, Padua, Italy
Eur J Surg Oncol 35:168-73. 2009..g. radical resection vs. local excision). The aim of this study was to determine the best lymph node size cut-off at computed tomography (CT) to predict nodal metastasis in rectal cancer patients with and without preoperative CRT...
- High prevalence of isolated tumour cells in regional lymph nodes from pN0 colorectal cancerC Mescoli
Department of Diagnostic Sciences and Special Therapies, Pathology Unit, Istituto Oncologico Veneto IRCCS, Universita degli Studi di Padova, Padova, Italy
J Clin Pathol 59:870-4. 2006..pN0 early-relapsing CRC can be explained by lymph node-ITC...
- Pericentriolar material analyses in normal esophageal mucosa, Barrett's metaplasia and adenocarcinomaDaniela Segat
Proliferation Unit, Department of Biology, University of Padova, Italy
Histol Histopathol 25:551-60. 2010..Extending our observations in a prospective study might help in the development of new prevention protocols for adenocarcinoma patients...
- The p53 gene in patients under the age of 40 with gastric cancer: mutation rates are low but are associated with a cardiac locationM Rugge
Department of Oncology and Surgical Sciences, University of Padova, ULSS15 Regione Veneto, Italy
Mol Pathol 53:207-10. 2000..Determining both the frequency and the spectrum of p53 gene mutation in young patients with gastric cancer might provide clues to the host related genetic mechanism(s) in gastric carcinogenesis...
- Helicobacter pylori virulence genes and host IL-1RN and IL-1beta genes interplay in favouring the development of peptic ulcer and intestinal metaplasiaC F Zambon
Department of Laboratory Medicine, University of Padova, Italy
Cytokine 18:242-51. 2002..An interplay between bacterial virulence factors and cytokines genotypes, is probably the main route causing H. pylori infection to lead to benign mild disease, benign severe disease or preneoplastic lesions...
- Staging and grading of chronic gastritisMassimo Rugge
Department of Oncological and Surgical Sciences, University of Padova, Italy
Hum Pathol 36:228-33. 2005..This system could offer gastroenterologists a more immediate perception of the overall condition of the gastric mucosa while also providing useful information about gastric cancer risk...
- Non-invasive diagnosis of Helicobacter pylori infection: simplified 13C-urea breath test, stool antigen testing, or DNA PCR in human feces in a clinical laboratory setting?Carlo Federico Zambon
Department of Medical and Surgical Sciences, University of Padova, Italy
Clin Biochem 37:261-7. 2004..2) To ascertain whether a simplified UBT (breath collection time = 10 min) is as reliable as the standard assay (30 min)...
- The potential of restaging in the prediction of pathologic response after preoperative chemoradiotherapy for rectal cancerIsacco Maretto
Department of Oncological and Surgical Sciences, Clinica Chirurgica II, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy
Ann Surg Oncol 14:455-61. 2007....
- Fibrosis in chronic hepatitis C acquired in infancy: is it only a matter of time?Maria Guido
Dipartimento di Scienze Oncologiche and Chirurgiche, Universita degli Studi di Padova, Azienda Ospedale Padova, Padova, Italy
Am J Gastroenterol 98:660-3. 2003..The natural history of chronic hepatitis C acquired in infancy is not well understood. The progression of fibrosis was analyzed in untreated children with chronic hepatitis C virus infection and no other hepatotoxic cofactors...
- Nuclear DNA content and pathology in radically treated pancreatic carcinoma. The prognostic significance of DNA ploidy, histology and nuclear gradeM Rugge
Cattedra di Istochimica and Immunoistochimica Patologica, Università di Padova ULSS 15 Veneto, Italy
Cancer 77:459-66. 1996..Histopathology and DNA ploidy were each correlated with survival in radically treated PC to ascertain the hierarchy of their prognostic significance...
- Helicobacter pylori, inflammation, oxidative damage and gastric cancer: a morphological, biological and molecular pathwayFabio Farinati
Departments of Surgical and Gastroenterological Sciences, Padua University, Padua, Italy
Eur J Cancer Prev 17:195-200. 2008..The growing body of evidence of the regression of precancerous changes and the high prevalence of superficial gastric carcinoma demonstrated in long-term follow-up studies on NiN make this approach mandatory...
- Differential effects of Helicobacter pylori eradication on oxidative DNA damage at the gastroesophageal junction and at the gastric antrumFabio Farinati
Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Sezione di Gastroenterologia, Policlinico Universitario, Via Giustiniani 2, 35128 Padova, Italy
Cancer Epidemiol Biomarkers Prev 13:1722-8. 2004..This prospective study evaluates DNA oxidative damage in biopsy samples obtained from both the antrum and the gastroesophageal junction (GEJ) before and after H. pylori eradication...
- Oxidative DNA damage in gastric cancer: CagA status and OGG1 gene polymorphismFabio Farinati
Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Universita di Padova, Padova, Italy
Int J Cancer 123:51-5. 2008..OGG1 1245C-->G polymorphism was common in both GC and IMA, but very rare in controls, and correlated more closely with 8-OHdG levels than do H. pylori infection or cagA status...
- [Fever of unknown origin and monoclonal gammapathy with unclear significance. Report of 2 cases with different pathology and clinical course]Giuseppe Realdi
Dipartimento di Scienze Mediche e Chirurgiche, Universita degli Studi di Padova
Ann Ital Med Int 19:214-29. 2004
- 5-fluorouracil and weekly oxaliplatin combined with radiotherapy for locally advanced rectal cancer: surgical complications and long-term resultsSalvatore Pucciarelli
Clinica Chirurgica II, Dipartimento di Scienze Oncologiche e Chirurgiche, Policlinico, Padova, Italy
Arch Med Res 37:860-5. 2006..We undertook this study to evaluate early surgical complications and long-term results after preoperative radiotherapy and chemotherapy (RCT) using 5-fluorouracil (5-FU) and oxaliplatin (OXA) for rectal cancer...
- Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphismsDaniela Basso
Department of Laboratory Medicine, University of Padova, Padova, Italy
Gastroenterology 135:91-9. 2008..We assessed the association of new and established cagA and vacA polymorphisms with disease...
- Prospective assessment of imaging after preoperative chemoradiotherapy for rectal cancerFabio Pomerri
Department of Medical Diagnostic Sciences and Special Therapies, University of Padua, Padua, Italy
Surgery 149:56-64. 2011....
- Hepatic spleen nodules (HSN)Claudia Mescoli
Department of Pathology, University of Padova, Padova, Italy
Scand J Gastroenterol 45:628-32. 2010..Although they are rare, hepatic spleen nodules should always be included in the diagnostic spectrum of nodular liver lesions because of their impact on treatment decisions...
- Prediction of lymph node status in superficial esophageal carcinomaErmanno Ancona
Istituto Oncologico Veneto IOV IRCCS University of Padova School of Medicine, Padova, Italy
Ann Surg Oncol 15:3278-88. 2008..Real chances for cure depend on both early recognition and early treatment. The ability to predict lymph node involvement allows early curative treatment with less invasive approaches...
- Donor livers with steatosis are safe to use in hepatitis C virus-positive recipientsPatrizia Burra
Gastroenterology Section, Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Liver Transpl 15:619-28. 2009..Steatotic grafts do not seem to exacerbate the progression of fibrosis in HCV+ recipients, nor do they seem to negatively affect 3-year patient survival...
- Trefoil peptides, E-cadherin, and beta-catenin expression in sporadic fundic gland polyps: further evidence toward the benign nature of these lesionsAnna D'Odorico
Department of Surgical and Gastroenterological Sciences, University of Padua, Padova, Italy
Appl Immunohistochem Mol Morphol 17:431-7. 2009..In conclusion all the factors considered were normally expressed in FGP and this, especially considered against the findings in IM-gastritis, supports the benign nature of FGP...
- Hepatitis C virus reinfection in liver transplant patients: evaluation of liver damage progression with echo-color DopplerMassimo Bolognesi
Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
Liver Transpl 14:616-24. 2008..In conclusion, the information obtainable from splanchnic Doppler parameters can be used to monitor the progression of liver fibrosis in transplant patients with HCV reinfection...
- Liver transplantation for the treatment of moderately or well-differentiated hepatocellular carcinomaUmberto Cillo
Clinica Chirurgica I, Dipartimento di Scienze Chirurgiche e Gastroenterlogiche, Italy
Ann Surg 239:150-9. 2004..To determine the long-term results of liver transplantation for well- or moderately differentiated hepatocellular carcinoma (HCC)...
- Acute liver rejection: accuracy and predictive values of doppler US measurements--initial experienceMassimo Bolognesi
Department of Clinical and Experimental Medicine, Institute of General Surgery, Clinica Medica 5, Policlinico Universitario, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
Radiology 235:651-8. 2005....
- Non-invasive neoplasia of the stomachMassimo Rugge
Department of Oncological and Surgical Sciences Pathology Unit, Universita degli Studi di Padova, Italy
Eur J Gastroenterol Hepatol 17:1191-6. 2005..The molecular profile of NiN is summarized and the spectrum of the options in the clinical management of gastric NiN are reported...
- Features predicting unresectability in hepatoblastomaLorenzo D'Antiga
Department of Pediatrics, University of Padova, Padova, Italy
Cancer 110:1050-8. 2007..The authors sought to identify presenting features that would predict unresectability in patients with HB and to provide suggestions for early referral and listing for OLT...
- Molecular characteristics in papillary thyroid cancers (PTCs) with no 131I uptakeCaterina Mian
Endocrinology Unit, Department of Medical and Surgical Sciences, University of Padua, Italy
Clin Endocrinol (Oxf) 68:108-16. 2008..Papillary thyroid cancers (PTCs) with no iodine uptake have an aggressive behaviour and a poor prognosis. The aim of our study was to characterize, at molecular level, a subset of PTC with no 131 iodine ((131)I) uptake...
- Different hemodynamic patterns of alcoholic and viral endstage cirrhosis: analysis of explanted liver weight, degree of fibrosis and splanchnic Doppler parametersMassimo Bolognesi
Department of Clinical and Experimental Medicine, University of Padua, Italy
Scand J Gastroenterol 42:256-62. 2007..The objective of this study was to investigate the role of the etiology of liver disease on the relationship between liver blood flow and liver pathology in endstage cirrhosis...
- Liver biopsy sampling in chronic viral hepatitisMaria Guido
Universita degli Studi di Padova, Azienda Ospedale, Padova, Italy
Semin Liver Dis 24:89-97. 2004..Integrating earlier experience with more recently produced data indicates that a biopsy sample 2 cm or more in length containing at least 11 complete portal tracts should be reliable for grading and staging chronic viral hepatitis...
- Oxidative damage, pro-inflammatory cytokines, TGF-alpha and c-myc in chronic HCV-related hepatitis and cirrhosisFabio Farinati
Department of Surgical and Gastroenterological Sciences, University of Padua, Italy
World J Gastroenterol 12:2065-9. 2006..To assess whether a correlation exists between oxidative DNA damage occurring in chronic HCV-related hepatitis and expression levels of pro-inflammatory cytokines, TGF-alpha and c-myc...
- Pro- and anti-inflammatory cytokines gene polymorphisms and Helicobacter pylori infection: interactions influence outcomeCarlo F Zambon
Department of Medical and Surgical Sciences, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
Cytokine 29:141-52. 2005..In conclusion, among host genetic factors contributing to H. pylori disease outcome, IFN-G +874 AA genotype favors cagA positive infections, TNF-A -857 TT duodenal ulcer while IL-10 -819 TT intestinal metaplasia and NCGC...
- Microwave thermal ablation for hepatocarcinoma: six liver transplantation casesG Zanus
General Surgery and Organ Transplantation, Hepatobiliary Surgery and Liver Transplant Unit, Azienda Università di Padova, Padova, Italy
Transplant Proc 43:1091-4. 2011..In conclusion, a MWA seemed to be a safe novel approach to treat HCC and could serve as a "bridge" to OLT and down-staging for patients with HCC...
- The Veneto Region's Barrett's Oesophagus Registry: aims, methods, preliminary resultsG Zaninotto
Department of General Surgery and Organ Transplantation, University of Padova, Padova, Italy
Dig Liver Dis 39:18-25. 2007..A Barrett's Oeosphagus Registry has been therefore established in the Veneto Region and neighbouring provinces...
- Micronuclei and broken eggs in human liver carcinogenesisMaria Guido
Department of Diagnostic Medical Sciences and Special Therapies, Pathology Unit, Universita degli Studi di Padova, Italy
Anticancer Res 28:2507-11. 2008..MNi/BE formation may result in activation of the p53-mediated cell cycle checkpoint...
- Liver steatosis in children with chronic hepatitis CMaria Guido
Department of Oncological and Surgical Sciences Pathology Section, University of Padova, Azienda Ospedaliera, Padova, Italy
Am J Gastroenterol 101:2611-5. 2006....
- IL-4 -588C>T polymorphism and IL-4 receptor alpha [Ex5+14A>G; Ex11+828A>G] haplotype concur in selecting H. pylori cagA subtype infectionsCarlo Federico Zambon
Department of Medical and Surgical Sciences, University of Padova, Italy
Clin Chim Acta 389:139-45. 2008..pylori virulence genes or H. pylori associated diseases...
- Determining therapeutic approaches in the elderly with rectal cancerLara Maria Pasetto
Medical Oncology 2nd, Istituto Oncologico Veneto, Padova, Italy
Drugs Aging 24:781-90. 2007..To evaluate the toxicity and feasibility of pelvic radiotherapy (RT) and/or surgery in elderly patients with locally advanced low-lying rectal cancer...
- Primary squamous cell carcinoma of the thyroid: immunohistochemical profile and literature reviewMatteo Fassan
Pathology Unit, Department of Medical Diagnostic Sciences and Special Therapies, University of Padua, Padua, Italy
Tumori 93:518-21. 2007..Squamous cell carcinoma accounts for 1% of primary thyroid malignancies and is characterized by a rapidly unfavorable outcome...
- Spontaneous regression of hepatitis B virus-associated cirrhosis developed in childhoodF Bortolotti
Department of Clinical and Experimental Medicine, Clinica Medica 5, University of Padua, Policlinico, Via Giustiniani 2, Italy
Dig Liver Dis 37:964-7. 2005..Subsidence of virus replication and of necro-inflammatory process and the efficiency of liver regeneration and repair might contribute to this favourable outcome...
- Histology predicts cirrhotic evolution of post transplant hepatitis CM Guido
Department of Oncology and Surgical Sciences, University of Padova, Italia
Gut 50:697-700. 2002..Hepatitis C recurring after orthotopic liver transplantation varies in severity and some patients rapidly develop fully established liver cirrhosis. Neither clinical nor biological markers of such rapid cirrhotic evolution are available...
- Bronchial carcinoid tumours in children: surgical treatment and outcome in a single institutionG Rizzardi
Thoracic Surgery, Cardio vascular thoracic Science, Padova, Italy
Eur J Pediatr Surg 19:228-31. 2009..Although rare, they represent the most common primary bronchial tumours in childhood. The aim of our study was to analyse the long-term survival and surgical treatment outcome in our young patients operated for carcinoid tumour...
- Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphismsCarlo Federico Zambon
Departments of Medical and Surgical Sciences, Laboratory Medicine, Oncological and Surgical Sciences, Gastroenterology, and Pathology, University of Padova, Padova, Italy
Gastroenterology 126:382-4. 2004
- Rectal cancer neoadjuvant treatment in elderly patientsLara Maria Pasetto
Medical Oncology Department, Istituto Oncologico Veneto, Padova, Italy
Anticancer Res 26:3913-23. 2006..A secondary endpoint was to identify any specific comorbidity that affected either effectiveness or morbidity of treatment...
- Galectin-3 cytotest in thyroid follicular neoplasia: a prospective, monoinstitutional studyGianmaria Pennelli
Veneto Institute of Oncology, Department of Medical Diagnostic Sciences and Special Therapies, University of Padova, Padova, Italy
Acta Cytol 53:533-9. 2009..To analyze the utility of galectin-3 (Gal3) immunohistochemistry (IHC) on preoperatively obtained fine needle aspiration biopsy (FNAB) in identifying the subgroup of follicular neoplasia (FN) patients who were candidates for thyroidectomy...
- Rectal cancer adjuvant chemotherapy: when is more useful?Lara Maria Pasetto
Oncologia Medical 2, Istituto Oncologico Veneto, IRCCS, Padova, Italy
Anticancer Res 28:1805-12. 2008..A secondary end-point was to identify the possible influence of clinical TNM (cTNM) or pathological TNM (pTNM) on TTP and overall survival (OS)...
- Dynamic changes of live/apoptotic circulating tumour cells as predictive marker of response to sunitinib in metastatic renal cancerE Rossi
Department of Surgery, Oncology and Gastroenterology, Oncology Section, University of Padova, Italy
Br J Cancer 107:1286-94. 2012..The test was first applied here to mRCC...
- Effects of interferon plus ribavirin treatment on NF-kappaB, TGF-beta1, and metalloproteinase activity in chronic hepatitis CMaria Guido
Section of Anatomic Pathology, Department of Oncological and Surgical Science, University of Padova, Italy
Mod Pathol 19:1047-54. 2006..Combination therapy with interferon and ribavirin affects the tissue expression of TGF-beta-1 and NF-kappaB and favors metalloproteinase activity, and may thereby modulate hepatic fibrogenetic events...
- Neoadjuvant chemoradiotherapy with 5-fluorouracil by bolusLara Maria Pasetto
Istituto Oncologico Veneto, IRCCS, Medical Oncology 2, Padova, Italy
Anticancer Res 28:4095-100. 2008..Since the presence of cardiomiopathy may contraindicate c.i. of 5-FU, an alternative regimen of 5-FU CT-RT was prospectively studied in these patients...
- BRAF in primary and recurrent papillary thyroid cancers: the relationship with (131)I and 2-[(18)F]fluoro-2-deoxy-D-glucose uptake abilitySusi Barollo
Istituto Oncologico Veneto IRCCS, Padova, Italy
Eur J Endocrinol 163:659-63. 2010..In a previous report, we showed that recurrent PTC with no radioiodine ((131)I) uptake are frequently associated with BRAF mutations, a low expression of thyroid-related genes and a high expression of glucose type-1 transporter gene...
- Restorative proctocolectomy for inflammatory bowel disease: the Padova prognostic score for colitis in predicting long-term outcome and quality of lifeMarco Scarpa
Department of Surgery, Veneto Oncological Institute IOV IRCCS, Padua, Italy
Int J Colorectal Dis 24:1049-57. 2009....
- Antibodies against synthetic deamidated gliadin peptides for celiac disease diagnosis and follow-up in childrenDaniela Basso
Department of Laboratory Medicine, University of Padova, Italy
Clin Chem 55:150-7. 2009..AGA IgA II and AGA IgG II have recently been suggested as reliable tools for celiac disease (CD) diagnosis. We compared their utility for diagnosis and monitoring CD in children with that of tTG IgA, an established CD marker...
- Does Helicobacter pylori infection eradication modify peptic ulcer prevalence? A 10 years' endoscopical surveyGiorgio Nervi
Dipartimento di Scienze Cliniche, Sezione di Gastroenterologia, Azienda Ospedaliera Universitaria di Parma, V Gramsci 14, 43100 Parma, Italy
World J Gastroenterol 12:2398-401. 2006..To compare peptic ulcer prevalence in patients referred for upper gastrointestinal endoscopy in two Italian hospitals in pre-Helicobacter era and ten years after the progressive diffusion of eradication therapy...
- Natural course of functional dyspepsia after Helicobacter pylori eradication: a seven-year surveyFrancesco Di Mario
University of Parma, Parma, Italy
Dig Dis Sci 50:2286-95. 2005..FD symptoms slightly improve after Hp eradication over a long period of time but a large percentage of these improved patients may experience FD symptoms again, even after some years of well-being after Hp eradication...
- Assessing risks for gastric cancer: new tools for pathologistsRobert M Genta
Pathology and Laboratory Service 113, VA North Texas Health Care System, 4500 S Lancaster Road, Dallas, TX 75216, USA
World J Gastroenterol 12:5622-7. 2006..Such an integrated report could facilitate clinicians' approach to the management of patients with gastric conditions...
- Rabeprazole in a one-week eradication therapy of Helicobacter pylori: comparison of different dosagesFrancesco Di Mario
Department of Clinical Science, University of Parma, Parma, Italy
J Gastroenterol Hepatol 18:783-6. 2003..We report the efficacy and tolerability of rabeprazole in different dosages in association with clarithromycin (C)and tinidazole (T) in H. pylori eradication...
- Serological markers for gastric atrophy in asymptomatic patients infected with Helicobacter pyloriChiara Ricci
Department of Internal Medicine and Gastroenterology, University of Bologna, University Hospital S Orsola Malpighi, Bologna, Italy
Am J Gastroenterol 99:1910-5. 2004..pylori) infection. This blinded, controlled study was designed to determine if serum gastrin and pepsinogens were reliable markers of atrophy in asymptomatic patients...
- Asthma-like syndrome in a teenagerAngelo Barbato
Pediatr Allergy Immunol 14:412-3. 2003
- Usefulness of serum pepsinogens in Helicobacter pylori chronic gastritis: relationship with inflammation, activity, and density of the bacteriumFrancesco Di Mario
Chair of Gastroenterology, Department of Clinical Sciences, University of Parma, Via Gramsci 14, 43100 Parma, Italy
Dig Dis Sci 51:1791-5. 2006..33, P < .001) and intestinal metaplasia (r = -0.37, P < .001) in the corpus. sPGII levels could be considered as markers of gastric inflammation all over in the stomach. sPGI levels are inversely related to atrophic body gastritis...
- Primary rectal carcinoma in patients with stage IV resectable disease at diagnosisLara Maria Pasetto
Medical Oncology Department, Via Gattamelata 64, Istituto Oncologico Veneto, 35128 Padova, Italy
Anticancer Res 27:1079-85. 2007..The purpose of this study was to review the feasibility and outcome of multimodality treatment of rectal cancer patients metastatic at diagnosis...
- Early epigastric pain after PPI administration: exacerbation of Helicobacter pylori corpus gastritis?Francesco Di Mario
Helicobacter 9:92-4. 2004