Massimo Iacoviello

Summary

Affiliation: University of Bari
Country: Italy

Publications

  1. doi request reprint Independent role of left ventricular global longitudinal strain in predicting prognosis of chronic heart failure patients
    Massimo Iacoviello
    Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy
    Echocardiography 30:803-11. 2013
  2. ncbi request reprint Ventricular repolarization dynamicity provides independent prognostic information toward major arrhythmic events in patients with idiopathic dilated cardiomyopathy
    Massimo Iacoviello
    Institute of Cardiology, University of Bari, Bari, Italy
    J Am Coll Cardiol 50:225-31. 2007
  3. doi request reprint Independent role of reduced arterial baroreflex sensitivity during head-up tilt testing in predicting vasovagal syncope recurrence
    Massimo Iacoviello
    Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
    Europace 12:1149-55. 2010
  4. doi request reprint Altered two-dimensional strain measures of the right ventricle in patients with Brugada syndrome and arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Massimo Iacoviello
    Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
    Eur J Echocardiogr 12:773-81. 2011
  5. doi request reprint Clinical predictors of head-up tilt test outcome during the nitroglycerin phase
    Massimo Iacoviello
    Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
    Clin Auton Res 20:167-73. 2010
  6. ncbi request reprint Prognostic role of sub-clinical hypothyroidism in chronic heart failure outpatients
    M Iacoviello
    Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
    Curr Pharm Des 14:2686-92. 2008
  7. doi request reprint Impaired arterial baroreflex function before nitrate-induced vasovagal syncope during head-up tilt test
    Massimo Iacoviello
    Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
    Europace 10:1170-5. 2008
  8. ncbi request reprint Alpha- and beta-adrenergic receptor polymorphisms in hypertensive and normotensive offspring
    Massimo Iacoviello
    Institute of Cardiology, University of Bari, Bari, Italy
    J Cardiovasc Med (Hagerstown) 7:316-21. 2006
  9. ncbi request reprint Beta1- and beta2-adrenergic receptor polymorphisms affect susceptibility to idiopathic dilated cardiomyopathy
    Cinzia Forleo
    Institute of Cardiology, University of Bari, Bari, Italy
    J Cardiovasc Med (Hagerstown) 8:589-95. 2007
  10. ncbi request reprint Ventricular asynchrony predicts a better outcome in patients with chronic heart failure receiving cardiac resynchronization therapy
    Maria Vittoria Pitzalis
    Institute of Cardiology, University of Bari, Bari, Italy
    J Am Coll Cardiol 45:65-9. 2005

Collaborators

Detail Information

Publications46

  1. doi request reprint Independent role of left ventricular global longitudinal strain in predicting prognosis of chronic heart failure patients
    Massimo Iacoviello
    Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy
    Echocardiography 30:803-11. 2013
    ..To evaluate the independent prognostic role of two-dimensional (2D) strain measures reflecting global longitudinal left ventricular (LV) systolic function in outpatients affected by chronic heart failure (CHF)...
  2. ncbi request reprint Ventricular repolarization dynamicity provides independent prognostic information toward major arrhythmic events in patients with idiopathic dilated cardiomyopathy
    Massimo Iacoviello
    Institute of Cardiology, University of Bari, Bari, Italy
    J Am Coll Cardiol 50:225-31. 2007
    ..The purpose of this work was to evaluate whether ventricular repolarization dynamicity predicts major arrhythmic events in patients with idiopathic dilated cardiomyopathy (DCM)...
  3. doi request reprint Independent role of reduced arterial baroreflex sensitivity during head-up tilt testing in predicting vasovagal syncope recurrence
    Massimo Iacoviello
    Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
    Europace 12:1149-55. 2010
    ..The aim of this study was to evaluate the role of arterial baroreflex sensitivity (BRS) at baseline and during head-up tilt testing (HUT) in predicting the recurrence of VVS...
  4. doi request reprint Altered two-dimensional strain measures of the right ventricle in patients with Brugada syndrome and arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Massimo Iacoviello
    Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
    Eur J Echocardiogr 12:773-81. 2011
    ....
  5. doi request reprint Clinical predictors of head-up tilt test outcome during the nitroglycerin phase
    Massimo Iacoviello
    Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
    Clin Auton Res 20:167-73. 2010
    ..Given the few data currently available, the aim of this study was to assess correlations between nitrate-induced HUT outcomes and the clinical characteristics of patients...
  6. ncbi request reprint Prognostic role of sub-clinical hypothyroidism in chronic heart failure outpatients
    M Iacoviello
    Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
    Curr Pharm Des 14:2686-92. 2008
    ..It has been suggested that low thyroid hormones levels may be associated with increased mortality in patients with cardiovascular disease...
  7. doi request reprint Impaired arterial baroreflex function before nitrate-induced vasovagal syncope during head-up tilt test
    Massimo Iacoviello
    Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
    Europace 10:1170-5. 2008
    ..The aim of this study was to evaluate arterial baroreflex control of heart rate immediately before head-up tilt test (HUT)-induced vasovagal syncope (VVS)...
  8. ncbi request reprint Alpha- and beta-adrenergic receptor polymorphisms in hypertensive and normotensive offspring
    Massimo Iacoviello
    Institute of Cardiology, University of Bari, Bari, Italy
    J Cardiovasc Med (Hagerstown) 7:316-21. 2006
    ..The present study aimed to verify whether these differences are associated with a different genotype distribution of functionally relevant polymorphisms of the alpha- and beta-adrenergic receptor (AR) genes...
  9. ncbi request reprint Beta1- and beta2-adrenergic receptor polymorphisms affect susceptibility to idiopathic dilated cardiomyopathy
    Cinzia Forleo
    Institute of Cardiology, University of Bari, Bari, Italy
    J Cardiovasc Med (Hagerstown) 8:589-95. 2007
    ..We investigated whether functionally relevant polymorphisms within the genes encoding for these receptors indicate susceptibility to idiopathic dilated cardiomyopathy (DCM)...
  10. ncbi request reprint Ventricular asynchrony predicts a better outcome in patients with chronic heart failure receiving cardiac resynchronization therapy
    Maria Vittoria Pitzalis
    Institute of Cardiology, University of Bari, Bari, Italy
    J Am Coll Cardiol 45:65-9. 2005
    ..The aim of this study was to evaluate whether the clinical benefit of cardiac resynchronization therapy (CRT) can be prospectively predicted by means of the baseline evaluation of left ventricular asynchrony...
  11. doi request reprint Lack of association between genetic polymorphisms affecting sympathetic activity and tilt-induced vasovagal syncope
    Sandro Sorrentino
    Department, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
    Auton Neurosci 155:98-103. 2010
    ..None of the considered polymorphisms influencing sympathetic activity is a major risk factor for vasovagal syncope in Italian patients...
  12. doi request reprint Endothelin system polymorphisms in tilt test-induced vasovagal syncope
    Sandro Sorrentino
    Emergency and Organ Transplantation Department, University of Bari, Italy
    Clin Auton Res 19:347-54. 2009
    ..As the endothelin system participates in the regulation of cardiovascular homeostasis, the aim of this study was to analyse the role of these genetic variants in influencing tilt-induced vasovagal syncope...
  13. doi request reprint Nitrate-potentiated head-up tilt testing in older patients: outcomes, hemodynamic responses and prodrome recognition
    Pietro Guida
    Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Piazza Giulio Cesare 11, Bari, Italy
    Pacing Clin Electrophysiol 33:1210-6. 2010
    ..To compare head-up tilt testing (HUT) outcomes and hemodynamic responses, and the prevalence and correlates of prodromes, in elderly and younger patients with suspected vasovagal syncope (VVS)...
  14. ncbi request reprint Association of beta-adrenergic receptor polymorphisms and progression to heart failure in patients with idiopathic dilated cardiomyopathy
    Cinzia Forleo
    Institute of Cardiology, University of Bari, Bari, Italy
    Am J Med 117:451-8. 2004
    ..We assessed the effects of beta-adrenergic receptor variants on heart failure in idiopathic dilated cardiomyopathy...
  15. ncbi request reprint Independent and incremental prognostic value of endogenous ouabain in idiopathic dilated cardiomyopathy
    Maria Vittoria Pitzalis
    Institute of Cardiology, University of Bari, Bari, Italy
    Eur J Heart Fail 8:179-86. 2006
    ..This study provides the first evidence that circulating EO is a novel, independent and incremental marker that predicts the progression of heart failure...
  16. ncbi request reprint Cardiac resynchronization therapy tailored by echocardiographic evaluation of ventricular asynchrony
    Maria Vittoria Pitzalis
    Institute of Cardiology, University of Bari, Policlinico, Piazza Giulio Cesare 11, 70124 Bari, Italy
    J Am Coll Cardiol 40:1615-22. 2002
    ..The value of interventricular and intraventricular echocardiographic asynchrony parameters in predicting reverse remodeling after cardiac resynchronization therapy (CRT) was investigated...
  17. ncbi request reprint Enhanced reflex response to baroreceptor deactivation in subjects with tilt-induced syncope
    Mariavittoria Pitzalis
    Institute of Cardiology, University of Bari, Italy
    J Am Coll Cardiol 41:1167-73. 2003
    ..We sought to evaluate whether changes in resting baroreflex control of heart rate are a distinctive feature of healthy subjects with a history of syncope prone to a positive tilt-test response...
  18. ncbi request reprint Incidence and prevalence of hypothyroidism in patients affected by chronic heart failure: role of amiodarone
    Vincenzo Triggiani
    Endocrinology and Metabolic Diseases, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy
    Endocr Metab Immune Disord Drug Targets 12:86-94. 2012
    ..Furthermore, amiodarone, an iodine-containing antiarhythmic drug frequently used in CHF patients, is often the cause of primary hypothyroidism...
  19. ncbi request reprint QT-interval prolongation in right precordial leads: an additional electrocardiographic hallmark of Brugada syndrome
    Maria Vittoria Pitzalis
    Institute of Cardiology, University of Bari, Bari, Italy
    J Am Coll Cardiol 42:1632-7. 2003
    ..e., right bundle branch block, coved-type ST-segment elevation, and T-wave inversion in the right precordial leads) is characterized by a concomitant lengthening of QT intervals in the right precordial leads...
  20. pmc The Renal Arterial Resistance Index Predicts Worsening Renal Function in Chronic Heart Failure Patients
    Massimo Iacoviello
    Cardiology Unit, Cardiothoracic Department, Policlinic University Hospital, Bari, Italy
    Cardiorenal Med 7:42-49. 2016
    ..The aim of this study was to verify the value of RRI as a predictor of worsening renal function (WRF) in a group of chronic heart failure (CHF) outpatients...
  21. ncbi request reprint Allelic variants of natriuretic peptide receptor genes are associated with family history of hypertension and cardiovascular phenotype
    Maria Vittoria Pitzalis
    Institute of Cardiology, University of Bari, Bari, Italy
    J Hypertens 21:1491-6. 2003
    ..We evaluated the associations between a family history of hypertension, cardiovascular phenotype and allelic variants of Npr1 and Npr3, two candidate genes that codify for natriuretic peptide receptors...
  22. doi request reprint Endothelin system polymorphisms in tilt test-induced vasovagal syncope
    Sandro Sorrentino
    Cardiology Unit, Emergency and Organ Transplantation Dept, University of Bari, Piazza Giulio Cesare 11, 70124, Bari, Italy
    Clin Auton Res 19:123-9. 2009
    ..As the endothelin system participates in the regulation of cardiovascular homeostasis, the aim of this study was to analyse the role of endothelin system polymorphisms in influencing tilt-induced vasovagal syncope...
  23. pmc Galectin-3 Serum Levels Are Independently Associated With Microalbuminuria in Chronic Heart Failure Outpatients
    Massimo Iacoviello
    Department of Cardiothoracic, Cardiology Unit, Policlinic University Hospital, Bari, Italy
    Res Cardiovasc Med 5:e28952. 2016
    ..Galectin-3 (Gal-3) is a novel biomarker reflecting inflammation status and fibrosis involving worsening of both cardiac and renal functions...
  24. doi request reprint Reversibility of the endothelial dysfunction after CPAP therapy in OSAS patients
    Marco Matteo Ciccone
    Department of Cardiology, University of Bari, Italy
    Int J Cardiol 158:383-6. 2012
    ....
  25. ncbi request reprint Comparison of the effect of valsartan and lisinopril on autonomic nervous system activity in chronic heart failure
    Elisabetta De Tommasi
    Institute of Cardiology, University of Bari, Bari, Italy
    Am Heart J 146:E17. 2003
    ..We sought to evaluate, in CHF, the different effects of an ACE inhibitor (lisinopril) and of an AT1 receptor antagonist (valsartan) on heart rate variability, baroreflex sensitivity and norepinephrine plasma levels...
  26. doi request reprint Prevalence, timing, and haemodynamic correlates of prodromes in patients with vasovagal syncope induced by head-up tilt test
    Pietro Guida
    Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
    Europace 11:1221-6. 2009
    ....
  27. doi request reprint Right Ventricular Longitudinal Strain Measures Independently Predict Chronic Heart Failure Mortality
    Massimo Iacoviello
    Cardiology Unit, Cardiothoracic Department, Policlinic University Hospital, Bari, Italy
    Echocardiography 33:992-1000. 2016
    ..In conclusion, our findings demonstrate the role of RV 2D strain measures to independently predict mortality. These data highlight the clinical usefulness of this echocardiographic approach in the daily management of HF outpatients. ..
  28. doi request reprint Clinical correlates of endothelial function in chronic heart failure
    Marco Matteo Ciccone
    Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy
    Clin Res Cardiol 100:515-21. 2011
    ..Brachial flow-mediated dilation (FMD) is a validated non-invasive measure of endothelial function. The aim of this study was to investigate the clinical correlates of FMD in patients with chronic heart failure (CHF)...
  29. doi request reprint Accuracy of bioimpedance vector analysis and brain natriuretic peptide in detection of peripheral edema in acute and chronic heart failure
    Francesco Massari
    Cardiology Section, F Perinei Hospital, Bari, Italy
    Heart Lung 45:319-26. 2016
    ..To evaluate the role of bioelectrical impedance vector analysis (BIVA) and brain natriuretic peptide (BNP) in detecting peripheral congestion in heart failure (HF)...
  30. ncbi request reprint Shortened head-up tilting test guided by systolic pressure reductions in neurocardiogenic syncope
    Mariavittoria Pitzalis
    Institute of Cardiology, and Innovative Technologies for Signal Detection and Processing Center, University of Bari, Bari, Italy
    Circulation 105:146-8. 2002
    ..Asymptomatic reductions in arterial pressure have been reported to occur before the onset of tilt-induced syncope. We investigated the predictive value of these reductions for a positive tilt result...
  31. pmc Ivabradine, coronary artery disease, and heart failure: beyond rhythm control
    Pietro Scicchitano
    Section of Cardiovascular Diseases, Department of Emergency and Organ Transplantation, University of Bari, School of Medicine, Policlinico, Bari, Italy
    Drug Des Devel Ther 8:689-700. 2014
    ..The aim of our review is to evaluate the role and the safety of this molecule on CAD and CHF therapeutic strategies. ..
  32. doi request reprint The renal arterial resistance index: a marker of renal function with an independent and incremental role in predicting heart failure progression
    Marco Matteo Ciccone
    Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari, Piazza Giulio Cesare 11, 70124, Bari, Italy
    Eur J Heart Fail 16:210-6. 2014
    ..The aim of the study was to evaluate clinical correlates and the prognostic relevance of RRI in a group of patients affected by chronic heart failure (CHF)...
  33. doi request reprint Head-up tilt testing for diagnosing vasovagal syncope: a meta-analysis
    Cinzia Forleo
    Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
    Int J Cardiol 168:27-35. 2013
    ..We conducted a meta-analysis of studies comparing HUT outcome between patients with syncope of unknown origin and control subjects without previous syncope...
  34. pmc Ventricular repolarization measures for arrhythmic risk stratification
    Francesco Monitillo
    Francesco Monitillo, Marta Leone, Caterina Rizzo, Massimo Iacoviello, Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, Italy
    World J Cardiol 8:57-73. 2016
    ....
  35. ncbi request reprint Mechanisms Explaining the Influence of Subclinical Hypothyroidism on the Onset and Progression of Chronic Heart Failure
    Vincenzo Triggiani
    1Endocrinology and Metabolic Diseases, Interdisciplinary Department of Medicine, University of Bari, Italy
    Endocr Metab Immune Disord Drug Targets 16:2-7. 2016
    ..Subclinical hypothyroidism can be associated with the onset and progression of chronic heart failure...
  36. pmc Clinical and functional characterization of a novel mutation in lamin a/c gene in a multigenerational family with arrhythmogenic cardiac laminopathy
    Cinzia Forleo
    Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy
    PLoS ONE 10:e0121723. 2015
    ..The combination of clinical, genetic, and functional data contribute insights into the pathogenesis of this form of life-threatening arrhythmogenic cardiac laminopathy. ..
  37. doi request reprint A novel cardiac bio-marker: ST2: a review
    Marco Matteo Ciccone
    Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation DETO, University of Bari, Bari 70124, Italy
    Molecules 18:15314-28. 2013
    ..The aim of this review is to explore the possible role of ST2 derived-protein as an early marker of cardiovascular diseases, above all in heart failure and ischemic heart diseases. ..
  38. pmc 12-lead electrocardiogram features of arrhythmic risk: A focus on early repolarization
    Caterina Rizzo
    Caterina Rizzo, Francesco Monitillo, School of Cardiology, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, Italy
    World J Cardiol 8:447-55. 2016
    ..The aim of this paper is to focus the attention on a new marker of arrhythmic risk, the early repolarization pattern in order to highlight the prognostic role of the 12-lead ECG. ..
  39. ncbi request reprint Neuro-psychological pattern in patients suffering from Primitive Dilated Cardiomyopathy with Impairment in Executive Function
    Rosa Carbonara
    Emergency and Organ Transplant Department, Cardiology Unit, University of Bari, Bari, Italy
    Curr Neurovasc Res . 2016
    ..Only the executive functions seem impaired in PDCM. Left ventricle dilation seems to be associated to attentive and executive functions decline...
  40. doi request reprint Pharmacokinetics and pharmacodynamics of ticagrelor when treating non-ST elevation acute coronary syndromes
    Francesco Monitillo
    University Hospital, Cardiology Unit and Cardiothoracic Department, Policlinico Consorziale, Bari, Italy
    Expert Opin Drug Metab Toxicol 11:977-93. 2015
    ..Prasugrel, another thienopyridine, has demonstrated more potent platelet inhibition and efficacy than clopidogrel, although this drug requires metabolic activation and is associated with increased risk of bleedings...
  41. ncbi request reprint Thyroid disorders in chronic heart failure: from prognostic set-up to therapeutic management
    Vincenzo Triggiani
    Endocrinology and Metabolic Diseases, Interdisciplinary Department of Medicine, University of Bari Aldo Moro School of Medicine, Policlinico, Bari, Italy
    Endocr Metab Immune Disord Drug Targets 13:22-37. 2013
    ..The aim of this review is to focus on the prognostic consequences of thyroid disorders in heart failure patients. Moreover, the therapeutical approach and the possible beneficial effects of restoring euthyroidism are reviewed. ..
  42. doi request reprint The glucocorticoid in acute decompensated heart failure: Dr Jekyll or Mr Hyde?
    Francesco Massari
    Cardiologia UTIC, ASL BA, Altamura, Bari, Italy
    Am J Emerg Med 30:517.e5-10. 2012
    ..These data support the possible usefulness of glucocorticoids in this setting...
  43. doi request reprint Could dilated cardiomyopathy alter the peripheral microcirculation and blood rheology?
    Giuseppe Cicco
    Interdepartmental Center of Research on Hemorheology, Microcirculation, Oxygen Transport and Non Invasive Optical Technologies, UniversitĂ  degli Studi di Bari Aldo Moro, Policlinico, Piazza G Cesare, 11 70124, Bari, Italy
    Adv Exp Med Biol 662:41-7. 2010
    ..Due to the lower oxygenation and to a non-significant increase in the number of capillaries after CRT, DCM patients are at higher cardiovascular risk than healthy subjects...
  44. pmc Increased carotid IMT in overweight and obese women affected by Hashimoto's thyroiditis: an adiposity and autoimmune linkage?
    Marco M Ciccone
    Department of Emergency and Organ Transplantation, University of Bari, Italy
    BMC Cardiovasc Disord 10:22. 2010
    ..Hashimoto's thyroiditis is a systemic disease. The aim is to examine whether autoimmune thyroiditis and adiposity can effect carotid IMT independently of thyroid hormones and cardiovascular risk factors...
  45. ncbi request reprint Intra-hospital correlations among 30-day mortality rates in 18 different clinical and surgical settings
    Pietro Guida
    Division of Cardiology and Cardiac Rehabilitation, S Maugeri Foundation, IRCCS, Institute of Cassano delle Murge, Via per Mercadante Km 2, 70020 Cassano Delle Murge, Bari, Italy
    Int J Qual Health Care . 2016
    ..To examine whether a correlation exists in hospitals among 30-day mortality rates for different types of hospitalizations...
  46. pmc Prognostic Role of Hypothyroidism in Heart Failure: A Meta-Analysis
    Ning Ning
    From the Department of Nuclear Medicine NN, The Second Affiliated Hospital, Xi an Jiaotong University School of Medicine, Xi an, Shaanxi, P R China Department of Cardiology DG, RM, YZ, HK, The Second Affiliated Hospital, Xi an Jiaotong University School of Medicine, Xi an, Shaanxi, P R China Endocrinology and Metabolic Diseases VT, Interdisciplinary Department of Medicine, University of Bari, Bari, Italy Cardiology Unit MI, Department of Emergency and Organs Transplantation, University of Bari, Bari, Italy and State University of New York Downstate Medical Center JE, Brooklyn, NY
    Medicine (Baltimore) 94:e1159. 2015
    ..Further diagnostic and therapeutic procedures for hypothyroidism may be needed for patients with HF. ..