Paolo Giunchedi

Summary

Affiliation: University of Sassari
Country: Italy

Publications

  1. doi request reprint Transarterial chemoembolization of hepatocellular carcinoma--agents and drugs: an overview. Part 2
    Paolo Giunchedi
    University of Sassari, Department of Chemistry and Pharmacy, Sassari, Italy
    Expert Opin Drug Deliv 10:799-810. 2013
  2. doi request reprint Transarterial chemoembolization of hepatocellular carcinoma. Agents and drugs: an overview. Part 1
    Paolo Giunchedi
    University of Sassari, Department of Chemistry and Pharmacy, Sassari, Italy
    Expert Opin Drug Deliv 10:679-90. 2013
  3. doi request reprint Evaluation of the effect of hydroxypropyl-β-cyclodextrin on topical administration of milk thistle extract
    Gianpiera Spada
    Department of Chemistry and Pharmacy, University of Sassari, Via Muroni 23 A, 07100 Sassari, Italy
    Carbohydr Polym 92:40-7. 2013
  4. doi request reprint Development of solid nanoparticles based on hydroxypropyl-β-cyclodextrin aimed for the colonic transmucosal delivery of diclofenac sodium
    Elisabetta Gavini
    Dipartimento di Scienze del Farmaco, University of Sassari, Via Muroni Dipartimento di Scienze Botaniche, Ecologiche e Geologiche, University of Sassari, Via Piandanna, Sassari Dipartimento di Chimica Farmaceutica, University of Pavia, Via Taramelli, Pavia, Italy
    J Pharm Pharmacol 63:472-82. 2011
  5. doi request reprint Solid lipid nanoparticles with and without hydroxypropyl-β-cyclodextrin: a comparative study of nanoparticles designed for colonic drug delivery
    Gianpiera Spada
    Department of Drug Sciences, University of Sassari, Sassari, Italy
    Nanotechnology 23:095101. 2012
  6. doi request reprint New chitosan derivatives for the preparation of rokitamycin loaded microspheres designed for ocular or nasal administration
    Giovanna Rassu
    Department of Drug Sciences, University of Sassari, Via Muroni 23 A, 07100 Sassari, Italy
    J Pharm Sci 98:4852-65. 2009
  7. pmc Solid microparticles based on chitosan or methyl-β-cyclodextrin: a first formulative approach to increase the nose-to-brain transport of deferoxamine mesylate
    Giovanna Rassu
    Department of Chemistry and Pharmacy, University of Sassari, Via Muroni 23 A, 07100 Sassari, Italy
    J Control Release 201:68-77. 2015
  8. ncbi request reprint Mucoadhesive microspheres for nasal administration of cyclodextrins
    Elisabetta Gavini
    Department of Drug Sciences, University of Sassari, Sassari, Italy
    J Drug Target 17:168-79. 2009
  9. doi request reprint Effect of chitosan malate on viability and cytoskeletal structures morphology of Caco-2 cells
    Claudia Juliano
    Dipartimento di Scienze del Farmaco, University of Sassari, Via Muroni 23 A, 07100 Sassari, Italy
    Int J Pharm 420:223-30. 2011
  10. ncbi request reprint Ketoprofen spray-dried microspheres based on Eudragit RS and RL: study of the manufacturing parameters
    Giovanna Rassu
    Department of Drug Sciences, University of Sassari, Sassari, Italy
    Drug Dev Ind Pharm 34:1178-87. 2008

Collaborators

  • Bruno Sarmento
  • Julietta V Rau
  • Cristina Lanni
  • Vanna Sanna
  • Stefano Fogli
  • Milena Sorrenti
  • Helene Jonassen
  • Ylenia Zambito
  • Claudia Juliano
  • Roberta Cavalli
  • Elisabetta Gavini
  • Giovanna Rassu
  • Massimo Cossu
  • Gianpiera Spada
  • Andrea Salis
  • Elena Soddu
  • Alessandro Dalpiaz
  • Luca Ferraro
  • Elena Piera Porcu
  • Nicola Marchetti
  • Antonio Carta
  • Antonio Brundu
  • Guido Cerri
  • Maria Cristina Bonferoni
  • Marta Roldo
  • Giuseppina Sandri
  • Silvia Rossi
  • Erzsébet Csányi
  • Rita Langasco
  • Raymond F Regan
  • Marcello Maestri
  • Mária Budai-Szucs
  • Paolo Dionigi
  • Szilvia Berkó
  • Ilaria Benzoni
  • Elena P Porcu
  • Sitaram Velaga
  • Sarah Beggiato
  • Pasquale Bandiera
  • Amjad Alhalaweh
  • Amanda Generosi
  • Antonio Brunetti
  • Marco Racchi
  • Tone Haukvik
  • Maria Cristina Breschi
  • Salvatore Marceddu
  • Corrado Muzzarelli
  • Marianna Usai
  • Mauro Marchetti
  • Jan Karlsen
  • Reeta Sharma

Detail Information

Publications21

  1. doi request reprint Transarterial chemoembolization of hepatocellular carcinoma--agents and drugs: an overview. Part 2
    Paolo Giunchedi
    University of Sassari, Department of Chemistry and Pharmacy, Sassari, Italy
    Expert Opin Drug Deliv 10:799-810. 2013
    ..An overview of the present situation in the field of TACE has been made, taking into account the materials constituting the embolizing agents and the way of controlled drug release...
  2. doi request reprint Transarterial chemoembolization of hepatocellular carcinoma. Agents and drugs: an overview. Part 1
    Paolo Giunchedi
    University of Sassari, Department of Chemistry and Pharmacy, Sassari, Italy
    Expert Opin Drug Deliv 10:679-90. 2013
    ..In the first part of this review, an overview of the present situation in the field of TACE has been made, referring in particular to the use of Lipiodol...
  3. doi request reprint Evaluation of the effect of hydroxypropyl-β-cyclodextrin on topical administration of milk thistle extract
    Gianpiera Spada
    Department of Chemistry and Pharmacy, University of Sassari, Via Muroni 23 A, 07100 Sassari, Italy
    Carbohydr Polym 92:40-7. 2013
    ....
  4. doi request reprint Development of solid nanoparticles based on hydroxypropyl-β-cyclodextrin aimed for the colonic transmucosal delivery of diclofenac sodium
    Elisabetta Gavini
    Dipartimento di Scienze del Farmaco, University of Sassari, Via Muroni Dipartimento di Scienze Botaniche, Ecologiche e Geologiche, University of Sassari, Via Piandanna, Sassari Dipartimento di Chimica Farmaceutica, University of Pavia, Via Taramelli, Pavia, Italy
    J Pharm Pharmacol 63:472-82. 2011
    ..Nanoparticles were designed for the oral administration and transmucosal colon delivery of drugs...
  5. doi request reprint Solid lipid nanoparticles with and without hydroxypropyl-β-cyclodextrin: a comparative study of nanoparticles designed for colonic drug delivery
    Gianpiera Spada
    Department of Drug Sciences, University of Sassari, Sassari, Italy
    Nanotechnology 23:095101. 2012
    ..The in vitro toxicity studies indicated that the SLN are well tolerated...
  6. doi request reprint New chitosan derivatives for the preparation of rokitamycin loaded microspheres designed for ocular or nasal administration
    Giovanna Rassu
    Department of Drug Sciences, University of Sassari, Via Muroni 23 A, 07100 Sassari, Italy
    J Pharm Sci 98:4852-65. 2009
    ..New polymers did not demonstrate cytotoxicity...
  7. pmc Solid microparticles based on chitosan or methyl-β-cyclodextrin: a first formulative approach to increase the nose-to-brain transport of deferoxamine mesylate
    Giovanna Rassu
    Department of Chemistry and Pharmacy, University of Sassari, Via Muroni 23 A, 07100 Sassari, Italy
    J Control Release 201:68-77. 2015
    ..Chitosan chloride and methyl-β-cyclodextrins appear therefore suitable to formulate solid microparticles able to promote the nose to brain uptake of DFO and to limit its systemic exposure...
  8. ncbi request reprint Mucoadhesive microspheres for nasal administration of cyclodextrins
    Elisabetta Gavini
    Department of Drug Sciences, University of Sassari, Sassari, Italy
    J Drug Target 17:168-79. 2009
    ..The microsphere properties are influenced by the kind of polymer, of cyclodextrin and by cyclodextrin to polymer ratio used. In particular, the alginate formulation containing the higher cyclodextrin content shows the best performance...
  9. doi request reprint Effect of chitosan malate on viability and cytoskeletal structures morphology of Caco-2 cells
    Claudia Juliano
    Dipartimento di Scienze del Farmaco, University of Sassari, Via Muroni 23 A, 07100 Sassari, Italy
    Int J Pharm 420:223-30. 2011
    ....
  10. ncbi request reprint Ketoprofen spray-dried microspheres based on Eudragit RS and RL: study of the manufacturing parameters
    Giovanna Rassu
    Department of Drug Sciences, University of Sassari, Sassari, Italy
    Drug Dev Ind Pharm 34:1178-87. 2008
    ..No effect of the container material is found...
  11. doi request reprint Engineered microparticles based on drug-polymer coprecipitates for ocular-controlled delivery of Ciprofloxacin: influence of technological parameters
    Elisabetta Gavini
    a Department of Chemistry and Pharmacy, University of Sassari, Sassari, Italy
    Drug Dev Ind Pharm 42:554-62. 2016
    ..A further improvement of the particle size characteristics has been obtained with the addition of surfactants. ..
  12. doi request reprint Propolis as lipid bioactive nano-carrier for topical nasal drug delivery
    Giovanna Rassu
    Department of Chemistry and Pharmacy, University of Sassari, 07100 Sassari, Italy Electronic address
    Colloids Surf B Biointerfaces 136:908-17. 2015
    ..Due to propolis composition, the proposed formulation could be used as a bioactive medication in which the carrier can exert a complementary effect with the loaded drug. ..
  13. doi request reprint Influence of polymeric microcarriers on the in vivo intranasal uptake of an anti-migraine drug for brain targeting
    Elisabetta Gavini
    Department of Chemistry and Pharmacy, University of Sassari, Sassari, Italy Electronic address
    Eur J Pharm Biopharm 83:174-83. 2013
    ..Among nasally administered formulations, CG microparticles showed the highest efficacy in promoting the central uptake of zolmitriptan within 1h. ..
  14. pmc Preparation, in vitro characterization and preliminary in vivo evaluation of buccal polymeric films containing chlorhexidine
    Claudia Juliano
    Department of Drug Sciences, University of Sassari, 07100 Sassari, Italy
    AAPS PharmSciTech 9:1153-8. 2008
    ..These preliminary results indicate that polymeric films can represent a valid vehicle for buccal delivery of antifungal/antimicrobial drugs...
  15. doi request reprint Development of thermosensitive chitosan/glicerophospate injectable in situ gelling solutions for potential application in intraoperative fluorescence imaging and local therapy of hepatocellular carcinoma: a preliminary study
    Andrea Salis
    a 1 University of Sassari, Department of Chemistry and Pharmacy, Sassari, Italy
    Expert Opin Drug Deliv 12:1583-96. 2015
    ..Indocyanine green (ICG) was loaded in the thermosensitive solutions in order to assess their potential for the detection of tumor nodules by fluorescence...
  16. doi request reprint From naturally-occurring neurotoxic agents to CNS shuttles for drug delivery
    Elena Soddu
    Department of Chemistry and Pharmacy, University of Sassari, 07100 Sassari, Italy
    Eur J Pharm Sci 74:63-76. 2015
    ..We hope to give insights to researchers toward developing new delivery systems that exploit the positive features of substances usually regarded as natural hazards. ..
  17. doi request reprint Composite chitosan/alginate hydrogel for controlled release of deferoxamine: A system to potentially treat iron dysregulation diseases
    Giovanna Rassu
    Department of Chemistry and Pharmacy, University of Sassari, Via Muroni 23, 07100 Sassari, Italy
    Carbohydr Polym 136:1338-47. 2016
    ..The inclusion of microspheres into pre-formed chitosan/alginate hydrogel provided the most efficient delivery system; the drug released from microspheres is strongly entrapped in the hydrogel network and slowly released by diffusion...
  18. ncbi request reprint Spray-dried microspheres based on methylpyrrolidinone chitosan as new carrier for nasal administration of metoclopramide
    Elisabetta Gavini
    Department of Drug Sciences, University of Sassari, Sassari, Italy
    Eur J Pharm Biopharm 68:245-52. 2008
    ..These in-vitro and ex-vivo preliminary results show that spray-dried microspheres based on MPC could be a suitable nasal delivery system for the administration of metoclopramide...
  19. doi request reprint Buccal tablets containing cysteine and chlorhexidine for the reduction of acetaldehyde levels in the oral cavity
    Claudia Juliano
    Department of Drug Sciences, University of Sassari, Italy
    Drug Dev Ind Pharm 37:1192-9. 2011
    ..Our findings support the hypothesis that the application of buccal devices containing cysteine and chlorhexidine could reduce salivary acetaldehyde levels and thus the incidence of upper gastrointestinal cancer in drinkers and smokers...
  20. doi request reprint Influence of chitosan glutamate on the in vivo intranasal absorption of rokitamycin from microspheres
    Elisabetta Gavini
    Department of Drug Sciences, University of Sassari, Sassari 07100, Italy
    J Pharm Sci 100:1488-502. 2011
    ..On the contrary, drug goes to the CSF and the bloodstream only after nasal administration of CG microparticles...
  21. ncbi request reprint Solid lipid microparticles (SLM) containing juniper oil as anti-acne topical carriers: preliminary studies
    Elisabetta Gavini
    Dipartimento di Scienze del Farmaco, University of Sassari, Sassari, Italy
    Pharm Dev Technol 10:479-87. 2005
    ..The SLM here described are promising carriers for the development of anti-acne topical formulations containing Juniper oil...