Affiliation: University of Padova
- Impact of community-acquired paediatric rotavirus gastroenteritis on family life: data from the REVEAL studyMarie Van der Wielen
The Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Belgium
BMC Fam Pract 11:22. 2010..Although the epidemiology of rotavirus gastroenteritis (RVGE) is well documented, there are few data on the impact of RVGE on the families of affected children...
- Current and future antiretroviral treatment options in paediatric HIV infectionCarlo Giaquinto
Department of Paediatrics, University of Padova, Padova, Italy
Clin Drug Investig 28:375-97. 2008....
- Multicenter prospective study of the burden of rotavirus acute gastroenteritis in Europe, 2004-2005: the REVEAL studyPierre Van Damme
Faculty of Medicine, Centre for the Evaluation of Vaccination, World Health Organization Collaborating Centre for the Control and Prevention of Viral Hepatitis, University of Antwerp, Antwerp, Antwerp, BE 2610, Belgium
J Infect Dis 195:S4-S16. 2007..Rotavirus is recognized as a significant cause of pediatric gastroenteritis worldwide. Comprehensive data on the burden of rotavirus disease in Europe were lacking...
- The role of genetic variants of Stromal cell-Derived Factor 1 in pediatric HIV-1 infection and disease progressionKetty Gianesin
Section of Oncology and Immunology, AIDS Reference Center, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
PLoS ONE 7:e44460. 2012..This effect is time-dependent and linked to the coreceptor-usage of viral variants that undergo evolution during the course of HIV-1 infection...
- Changing patterns of clinical events in perinatally HIV-1-infected children during the era of HAARTElena Chiappini
Department of Paediatrics, University of Florence, Via Luca Giordano 13, I 50132 Florence, Italy
AIDS 21:1607-15. 2007..The introduction of HAART has decreased mortality and progression to AIDS in perinatally HIV-1-infected children, but information on modification of the rate of specific clinical events is limited...
- Polymorphisms of innate immunity genes influence disease progression in HIV-1-infected childrenRiccardo Freguja
Department of Oncology and Surgical Sciences, AIDS Reference Centre, University of Padova, Padua, Italy
AIDS 26:765-8. 2012..The TLR9 1635AG genotype and TLR9 [G;G] haplotype were associated with rapid disease progression, whereas the DEFβ1 -44CG genotype and DEFβ1 [G;G] haplotype correlated with a better clinical outcome...
- Toll-like receptor 9 polymorphisms influence mother-to-child transmission of human immunodeficiency virus type 1Elisabetta Ricci
Department of Oncology and Surgical Sciences, Oncology Section, AIDS Reference Center, University of Padova, Via Gattamelata 64, 35128 Padova, Italy
J Transl Med 8:49. 2010..The aim of this study was to investigate the influence of genetic variants of TLR 9 gene on MTCT...
- Long-term decay of the HIV-1 reservoir in HIV-1-infected children treated with highly active antiretroviral therapyMarisa Zanchetta
Department of Oncology and Surgical Sciences, Unit of Viral Oncology, AIDS Reference Center, Padova, Italy
J Infect Dis 193:1718-27. 2006..These findings suggest that clearance of the viral reservoir in HAART-treated children may be influenced by immune repopulation and residual viral replication and may help in refining long-term treatment strategies...
- Age distribution of paediatric rotavirus gastroenteritis cases in Europe: the REVEAL studyCarlo Giaquinto
Department of Paediatrics, University of Padua, Via Giustiniani 3, Padua, Italy
Scand J Infect Dis 42:142-7. 2010..This could significantly reduce the substantial burden of this potentially serious childhood disease...
- Early therapy in HIV-1-infected children: effect on HIV-1 dynamics and HIV-1-specific immune responseMarisa Zanchetta
AIDS Reference Center, Unit of Viral Oncology, Department of Oncology and Surgical Sciences, University of Padova, IOV IRCCS, Italy
Antivir Ther 13:47-55. 2008..Few data have been reported that address the viral dynamics and immunological response in infants who initiated aggressive antiretroviral therapy (ART) shortly after birth...
- Nucleoside and nucleotide reverse transcriptase inhibitors in childrenCarlo Giaquinto
Department of Pediatrics, Universita di Padova, Padova, Italy
Clin Drug Investig 27:509-31. 2007..In this article we review the available information to facilitate selection of the best NRTI for backbone treatment in combination ART for HIV-infected children...
- Distribution of rotavirus genotypes in Europe, 2004-2005: the REVEAL StudyPierre Van Damme
Faculty of Medicine, Centre for the Evaluation of Vaccination, World Health Organization Collaborating Centre for the Control and Prevention of Viral Hepatitis, University of Antwerp, Antwerp, BE 2610, Belgium
J Infect Dis 195:S17-25. 2007..Rotavirus gastroenteritis (RVGE) constitutes a significant burden of pediatric disease. Knowledge of currently cocirculating rotavirus genotypes is required to help guide immunization strategies...
- Virologic, immunologic, and clinical benefits from early combined antiretroviral therapy in infants with perinatal HIV-1 infectionElena Chiappini
Department of Paediatrics, University of Florence, Florence, Italy
AIDS 20:207-15. 2006....
- Role of beta-defensin-1 polymorphisms in mother-to-child transmission of HIV-1Elisabetta Ricci
Department of Oncology and Surgical Sciences, Oncology Section, AIDS Reference Center, University of Padova, Padova, Italy
J Acquir Immune Defic Syndr 51:13-9. 2009..Defensins provide microbial barriers and function as effectors of innate immunity. This study investigated the relationship between genetic variants of beta-defensin-1 gene and MTCT of HIV-1...
- Update on antiretroviral therapy in paediatricsMartina Penazzato
Department of Paediatrics, University of Padua, Via Giustiniani 3, 35128 Padova, Italy
Antiviral Res 85:266-75. 2010..This article forms part of a special issue of Antiviral Research marking the 25th anniversary of Antiretroviral Drug Discovery and Development, vol. 85, issue 1, 2010...
- Antiretroviral therapy for prevention of mother-to-child HIV transmission : focus on single-dose nevirapineCarlo Giaquinto
Dipartimento di Pediatria, Universita di Padova, Padova, Italy
Clin Drug Investig 26:611-27. 2006....
- Premature aging and immune senescence in HIV-infected childrenKetty Gianesin
aDepartment of Surgery, Oncology and Gastroenterology DiSCOG, Section of Oncology and Immunology, Unit of Viral Oncology and AIDS Reference Center, University of Padova, Padova, Italy bUnitat d Infectologia, Servei de Pediatria Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain cIstituto Oncologico Veneto IOV IRCCS dDepartment of Mother and Child Health, University of Padova, Padova, Italy eClinical Laboratory Department, Hematology Unit, Hospital San Joan de Deu, Universitat de Barcelona, Barcelona, Spain
AIDS 30:1363-73. 2016..The effect of HIV and antiretroviral therapy (ART) exposure on the aging process of HIV-infected children may be more deleterious since their immune system coevolves from birth with HIV...
- Implementation and Operational Research: Implementation of the WHO 2011 Recommendations for Isoniazid Preventive Therapy (IPT) in Children Living With HIV/AIDS: A Ugandan ExperiencePaola Costenaro
Department of Mother and Child Health, University of Padova, Padova, Italy Nsambya Home Care of St Raphael of St Francis Hospital, Kampala, Uganda Research Center of Montreal University Health Center CRCHUM Global Health, Montreal, Quebec, Canada Associazione Casa Accoglienza alla Vita Padre Angelo, Trento, Italy Department of Paediatrics and Child Health, Tygerberg Children s Hospital and Stellenbosch University, Tygerberg, South Africa and MRC Clinical Trials Unit at UCL, London, United Kingdom
J Acquir Immune Defic Syndr 71:e1-8. 2016..Data are needed to assess the feasibility of the WHO 2011 intensified tuberculosis case finding/IPT clinical algorithm...
- The second generation of HIV-1 vertically exposed infants: a case series from the Italian Register for paediatric HIV infectionCarmelina Calitri
Department of Paediatrics, University of Turin, Turin, Italy
BMC Infect Dis 14:277. 2014....
- Programmatic impact of the evolution of WHO pediatric antiretroviral treatment guidelines for resource-limited countries (Tukula Fenna Project, Uganda)Martina Penazzato
Department of Paediatrics, University of Padua, Padua, Italy
J Acquir Immune Defic Syndr 61:522-5. 2012..World Health Organization (WHO) recommendations for the initiation of antiretroviral therapy (ART) in children were revised in 2010, but the programmatic impact has had limited study...
- Role of non-nucleoside reverse transcriptase inhibitors in treating HIV-infected childrenMartina Penazzato
Department of Paediatrics, University of Padua, Italy
Drugs 71:2131-49. 2011..In addition, this review also outlines available clinical data on etravirine and rilpivirine in the context of how these antiretrovirals may address some of the limitations of efavirenz and nevirapine in paediatric patients...
- Ocular involvement in an HIV-infected patient: not always an infectious disease. An interesting case without apparent causeElena Mozzo
Department of Child s and Woman s Health, University of Padova, Italy
Int J STD AIDS 27:1130-1133. 2016..Clinical and histopathological findings made idiopathic orbital inflammatory syndrome the most probable diagnosis for our patient...
- Immune reconstitution in HIV-1-infected children on antiretroviral therapy: role of thymic output and viral fitnessLucia Ometto
Department of Oncology and Surgical Sciences, Oncology Section, AIDS Reference Center, University of Padova, Italy
AIDS 16:839-49. 2002..To investigate the role of thymic output and viral fitness in immune reconstitution in HIV-1-infected children on antiretroviral therapy...
- Predictors of Treatment Failure in HIV-Positive Children Receiving Combination Antiretroviral Therapy: Cohort Data From Mozambique and UgandaPaola Costenaro
Department of Pediatrics, University of Padova, Italy
J Pediatric Infect Dis Soc 4:39-48. 2015..Delays detecting treatment failure and switching to second-line combination antiretroviral therapy (cART) are often observed in human immunodeficiency virus (HIV)-infected children of low-middle-income countries (LMIC)...
- European Society for Paediatric Infectious Diseases consensus recommendations for rotavirus vaccination in Europe: update 2014Timo Vesikari
From the Vaccine Research Centre, University of Tampere Medical School, Tampere, Finland Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium Department of Paediatrics, University of Padova, Padova, Italy Soroka University Medical Center, The Faculty of Health Sciences, Ben Gurion University of Negev, Beer Sheva, Israel Departments of Paediatrics, University Federico II, Naples, Italy Department of Paediatrics, The Medical University of Warsaw, Poland and Centre of Paediatrics, Vilnius University, Vilnius, Lithuania
Pediatr Infect Dis J 34:635-43. 2015..Although specific information on many immunodeficiencies is lacking, infants with known severe combined immunodeficiency should not receive live RV vaccine. ..
- Summary of effectiveness and impact of rotavirus vaccination with the oral pentavalent rotavirus vaccine: a systematic review of the experience in industrialized countriesCarlo Giaquinto
Department of Pediatrics, University of Padova, Padova, Italy
Hum Vaccin 7:734-48. 2011....
- Malaria prevention reduces in-hospital mortality among severely ill tuberculosis patients: a three-step intervention in Bissau, Guinea-BissauRaffaella Colombatti
Clinic of Pediatric Hematology Oncology, Department of Pediatrics, University of Padova, Padova, Italy
BMC Infect Dis 11:57. 2011..We performed a three-step malaria prevention program to reduce mortality in TB patients during the rainy season...
- Economics of rotavirus gastroenteritis and vaccination in Europe: what makes sense?Richard D Rheingans
Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA
Pediatr Infect Dis J 25:S48-55. 2006..Although methodologic limitations exist in applying the QALY approach to childhood vaccines, their use in cost effectiveness analyses allows decision makers to consider the full health benefits of rotavirus and other vaccines...
- Efficacy, safety and tolerability of tipranavir coadministered with ritonavir in HIV-1-infected children and adolescentsJuan C Salazar
Connecticut Children s Medical Center, University of Connecticut School of Medicine, Hartford, Connecticut 06106, USA
AIDS 22:1789-98. 2008..To evaluate the efficacy, safety and tolerability of ritonavir-boosted tipranavir (TPV/r) in HIV-1-infected pediatric patients...
- Older children and adolescents surviving with vertically acquired HIV infectionClaire Thorne
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London, UK
J Acquir Immune Defic Syndr 29:396-401. 2002..As they enter adolescence, additional services are needed including support with disclosure to others, therapy, and sexual health...
- Rotavirus types in Europe and their significance for vaccinationUlrich Desselberger
Cambridge, United Kingdom
Pediatr Infect Dis J 25:S30-41. 2006..A case is made for comprehensive surveillance of cocirculating human rotavirus types in Europe after the implementation of rotavirus vaccination...
- Genotypic resistance tests for the management of the HIV-infected pregnant patient in AfricaCarlo Giaquinto
Dipartimento di Pediatria, Universita di Padova, Italy
Scand J Infect Dis Suppl 106:88-90. 2003..Moreover, even in low-resource countries there are some special settings where DRT may be available for patient care and its use may be considered...
- Pharmacokinetics of nelfinavir and its active metabolite, hydroxy-tert-butylamide, in infants perinatally infected with human immunodeficiency virus type 1Catherine Litalien
Department of Pediatric Pharmacology and Pharmacogenetics, Hopital Robert Debre, Paris, France
Pediatr Infect Dis J 22:48-55. 2003..This study was conducted to determine the steady state pharmacokinetics of nelfinavir and its active metabolite, M8, in this population...
- Lopinavir/ritonavir exposure in treatment-naive HIV-infected children following twice or once daily administrationRaffaella Rosso
Department of Infectious Diseases, San Martino Hospital and University of Genoa, Largo Rosanna Benzi 10, 16132 Genoa, Italy
J Antimicrob Chemother 57:1168-71. 2006..However, once daily administration could increase convenience and patient adherence. Our study aimed at evaluating whether inhibitory concentrations are maintained in plasma following administration of lopinavir/ritonavir once daily...
- Pregnancy and HIV infection: A european consensus on managementOriol Coll
Hospital Clinic, University of Barcelona, Spain
AIDS 16:S1-18. 2002
- Clinical consequences of rotavirus acute gastroenteritis in Europe, 2004-2005: the REVEAL studyCarlo Giaquinto
Department of Pediatrics, University of Padua, Padua, Italy
J Infect Dis 195:S26-35. 2007..The availability of comprehensive, up-to-date epidemiologic data would improve the understanding of the disease burden and clinical consequences of rotavirus gastroenteritis (RVGE) in Europe...
- Costs of community-acquired pediatric rotavirus gastroenteritis in 7 European countries: the REVEAL StudyCarlo Giaquinto
Department of Pediatrics, University of Padua, Padua, Italy
J Infect Dis 195:S36-S44. 2007..Morbidity and resource use due to rotavirus gastroenteritis (RVGE) are substantial in Europe, although comprehensive data on the economic impact of the disease are lacking...
- A randomized controlled trial of genotypic HIV drug resistance testing in HIV-1-infected children: the PERA (PENTA 8) trialHannah Green
MRC Clinical Trials Unit, London, UK
Antivir Ther 11:857-67. 2006..To evaluate the longer-term utility of genotypic resistance testing in HIV-1-infected children with virological failure...
- RotavirusJim Gray
Centre for Infections, Health Protection Agency, London, UK
J Pediatr Gastroenterol Nutr 46:S24-31. 2008
- Nosocomial rotavirus infection in European countries: a review of the epidemiology, severity and economic burden of hospital-acquired rotavirus diseaseOlivier Gleizes
Smart Pharma Consulting, Paris, France
Pediatr Infect Dis J 25:S12-21. 2006....
- Effects of nutritional rehabilitation on intestinal function and on CD4 cell number in children with HIVAlfredo Guarino
Department of Pediatrics, University Federico II, Naples, Italy
J Pediatr Gastroenterol Nutr 34:366-71. 2002..The authors tested the hypothesis that nutritional support improves intestinal and immune functions in children infected with human immunodeficiency virus (HIV)...
- Withdrawal of Pneumocystis jirovecii prophylaxis in HIV-infected children under highly active antiretroviral therapySimon Urschel
University Children s Hospital, Munich, Germany
AIDS 19:2103-8. 2005..With regard to children only a small amount of data has been published. The present study investigated whether the withdrawal of PCP prophylaxis after immune reconstitution is safe in HIV-infected children...
- Intussusception among young children in EuropeHans Iko Huppertz
Prof Hess Kinderklinik, Bremen, Germany
Pediatr Infect Dis J 25:S22-9. 2006....
- Clinical trials of rotavirus vaccines in EuropeTimo Vesikari
University of Tampere Medical School, Tampere, Finland
Pediatr Infect Dis J 25:S42-7. 2006..A large scale safety trial, conducted in Latin America plus Finland, indicated no increased risk of intussusception among recipients of Rotarix compared with placebo. The licensure of Rotarix is in process in the European Union...
- Bayesian parameter estimates of nelfinavir and its active metabolite, hydroxy-tert-butylamide, in infants perinatally infected with human immunodeficiency virus type 1Salomé Payen
Laboratoire de Pharmacocinetique Clinique, Faculte de Pharmacie, BP 14491, 34093 Montpellier Cedex 5, France
Antimicrob Agents Chemother 49:525-35. 2005....
- Cancer rates after year 2000 significantly decrease in children with perinatal HIV infection: a study by the Italian Register for HIV Infection in ChildrenElena Chiappini
Department of Pediatrics, University of Florence, Florence, Italy
J Clin Oncol 25:97-101. 2007..To evaluate the impact of highly active antiretroviral therapy (HAART) on cancer incidence in HIV-infected children throughout a 20-year period...
- European Society for Paediatric Infectious Diseases/European Society for Paediatric Gastroenterology, Hepatology, and Nutrition evidence-based recommendations for rotavirus vaccination in EuropeTimo Vesikari
Vaccine Research Centre, University of Tampere Medical School, Tampere, Finland
J Pediatr Gastroenterol Nutr 46:S38-48. 2008
- European Society for Paediatric Infectious Diseases/European Society for Paediatric Gastroenterology, Hepatology, and Nutrition evidence-based recommendations for rotavirus vaccination in Europe: executive summaryTimo Vesikari
Vaccine Research Centre, University of Tampere Medical School, Tampere, Finland
J Pediatr Gastroenterol Nutr 46:615-8. 2008