Sebastiano Gangemi

Summary

Affiliation: University of Messina
Country: Italy

Publications

  1. pmc Protein carbonyl group content in patients affected by familiar chronic nail candidiasis
    S Gangemi
    Division and School of Allergy and Clinical Immunology, Department of Human Pathology, University of Messina, Italy
    Mediators Inflamm 12:247-9. 2003
  2. ncbi Correlation between serum retinol and alpha-tocopherol levels in centenarians
    Giorgio Basile
    Chair of Geriatrics, Division of Geriatric Medicine, University of Messina, Messina, Italy
    J Nutr Sci Vitaminol (Tokyo) 49:287-8. 2003
  3. pmc Effect of levodopa on interleukin-15 and RANTES circulating levels in patients affected by Parkinson's disease
    Sebastiano Gangemi
    School and Division of Allergy and Clinical Immunology, Via Centonze n 200 is 98, 98123 Messina, Italy
    Mediators Inflamm 12:251-3. 2003
  4. doi Changes in advanced oxidation protein products, advanced glycation end products, and s-nitrosylated proteins, in patients affected by polycythemia vera and essential thrombocythemia
    Caterina Musolino
    Division of Haematology, University of Messina, Messina, Italy
    Clin Biochem 45:1439-43. 2012
  5. doi Relationship between advanced oxidation protein products, advanced glycation end products, and S-nitrosylated proteins with biological risk and MDR-1 polymorphisms in patients affected by B-chronic lymphocytic leukemia
    Sebastiano Gangemi
    School and Division of Allergy and Clinical Immunology, Department of Human Pathology, University of Messina, Messina, Italy
    Cancer Invest 30:20-6. 2012
  6. doi Oxidative stress in oncohematologic diseases: an update
    Selene Imbesi
    Department of Clinical and Experimental Medicine, School and Unit of Allergy and Clinical Immunology, University of Messina, Messina, Italy
    Expert Rev Hematol 6:317-25. 2013
  7. doi Evaluation of interleukin-23 plasma levels in patients with polycythemia vera and essential thrombocythemia
    Sebastiano Gangemi
    School and Division of Allergy and Clinical Immunology, Department of Human Pathology, University of Messina, Italy
    Cell Immunol 278:91-4. 2012
  8. doi Increase of novel biomarkers for oxidative stress in patients with plasma cell disorders and in multiple myeloma patients with bone lesions
    Sebastiano Gangemi
    Department of Human Pathology, School and Division of Allergy and Clinical Immunology, University of Messina, Messina, Italy
    Inflamm Res 61:1063-7. 2012
  9. doi Increased serum levels of advanced oxidation protein products and glycation end products in subjects exposed to low-dose benzene
    Giovanna Spatari
    Department of Social and Environmental Medicine, University of Messina, Messina, Italy
    Int J Hyg Environ Health 215:389-92. 2012
  10. doi Serum levels of protein oxidation products in patients with nickel allergy
    Sebastiano Gangemi
    School and Division of Allergy and Clinical Immunology, Department of Human Pathology, University of Messina, Messina, Italy
    Allergy Asthma Proc 30:552-7. 2009

Collaborators

Detail Information

Publications74

  1. pmc Protein carbonyl group content in patients affected by familiar chronic nail candidiasis
    S Gangemi
    Division and School of Allergy and Clinical Immunology, Department of Human Pathology, University of Messina, Italy
    Mediators Inflamm 12:247-9. 2003
    ....
  2. ncbi Correlation between serum retinol and alpha-tocopherol levels in centenarians
    Giorgio Basile
    Chair of Geriatrics, Division of Geriatric Medicine, University of Messina, Messina, Italy
    J Nutr Sci Vitaminol (Tokyo) 49:287-8. 2003
    ..We assume that the preservation of normal values and the correlation between vitamin A and E concentrations protects centenarians against oxidative stress and contributes to their extreme longevity...
  3. pmc Effect of levodopa on interleukin-15 and RANTES circulating levels in patients affected by Parkinson's disease
    Sebastiano Gangemi
    School and Division of Allergy and Clinical Immunology, Via Centonze n 200 is 98, 98123 Messina, Italy
    Mediators Inflamm 12:251-3. 2003
    ..So, we hypothesize that the immunological alterations found in PD may be linked, at least in part, to levodopa therapy...
  4. doi Changes in advanced oxidation protein products, advanced glycation end products, and s-nitrosylated proteins, in patients affected by polycythemia vera and essential thrombocythemia
    Caterina Musolino
    Division of Haematology, University of Messina, Messina, Italy
    Clin Biochem 45:1439-43. 2012
    ..We also evaluated neutrophil gelatinase-associated lipocalin (NGAL) levels, an acute phase protein isolated in human neutrophils, the activation status of platelets and leukocytes, and the JAK2 (V617F) mutation status...
  5. doi Relationship between advanced oxidation protein products, advanced glycation end products, and S-nitrosylated proteins with biological risk and MDR-1 polymorphisms in patients affected by B-chronic lymphocytic leukemia
    Sebastiano Gangemi
    School and Division of Allergy and Clinical Immunology, Department of Human Pathology, University of Messina, Messina, Italy
    Cancer Invest 30:20-6. 2012
    ..Our results suggest that B-CLL is associated with oxidative stress...
  6. doi Oxidative stress in oncohematologic diseases: an update
    Selene Imbesi
    Department of Clinical and Experimental Medicine, School and Unit of Allergy and Clinical Immunology, University of Messina, Messina, Italy
    Expert Rev Hematol 6:317-25. 2013
    ..New approaches that aim to evaluate subcellular and microenvironment redox potential may be useful in developing cancer diagnostics and therapeutics...
  7. doi Evaluation of interleukin-23 plasma levels in patients with polycythemia vera and essential thrombocythemia
    Sebastiano Gangemi
    School and Division of Allergy and Clinical Immunology, Department of Human Pathology, University of Messina, Italy
    Cell Immunol 278:91-4. 2012
    ..In PV patients the JAK2 burden and Hb levels correlated with occurrence of pruritus. Our study seems to point out a possible involvement of IL-23 in the pathogenesis of PV...
  8. doi Increase of novel biomarkers for oxidative stress in patients with plasma cell disorders and in multiple myeloma patients with bone lesions
    Sebastiano Gangemi
    Department of Human Pathology, School and Division of Allergy and Clinical Immunology, University of Messina, Messina, Italy
    Inflamm Res 61:1063-7. 2012
    ..In this study, we analyzed the oxidative stress in untreated multiple myeloma (MM) patients and in patients affected by monoclonal gammopathy of uncertain significance (MGUS)...
  9. doi Increased serum levels of advanced oxidation protein products and glycation end products in subjects exposed to low-dose benzene
    Giovanna Spatari
    Department of Social and Environmental Medicine, University of Messina, Messina, Italy
    Int J Hyg Environ Health 215:389-92. 2012
    ..We can conclude that, in this condition, AOPPs are more sensitive marker of low benzene exposure than AGEs...
  10. doi Serum levels of protein oxidation products in patients with nickel allergy
    Sebastiano Gangemi
    School and Division of Allergy and Clinical Immunology, Department of Human Pathology, University of Messina, Messina, Italy
    Allergy Asthma Proc 30:552-7. 2009
    ....
  11. doi Effect of therapeutic plasma exchange on plasma levels of oxidative biomarkers in a patient with thrombotic thrombocytopenic purpura
    Sebastiano Gangemi
    School and Division of Allergy and Clinical Immunology, Department of Clinical and Expèerimental Medicine, University Hospital G Martino, Messina, Italy Institute of Clinical Physiology, IFC CNR, Messina Unit, Messina, Italy
    Eur J Haematol 94:368-73. 2015
    ..The role of oxidative stress in the initiation and progression of endothelial damage in thrombotic thrombocytopenic purpura (TTP) syndrome has been the subject of much speculation in the recent past...
  12. ncbi Lower platelet count in healthy centenarians correlates with dispersion of the QT interval
    Sebastiano Gangemi
    School of Allergy and Clinical Immunology, Department of Human Pathology, University of Messina, Messina, Italy
    Aging Clin Exp Res 16:169-71. 2004
    ..The aim of this study was to evaluate platelet count and QTd in healthy centenarians and to establish correlations between these two indices...
  13. pmc Age-related modifications in circulating IL-15 levels in humans
    Sebastiano Gangemi
    Department of Human Pathology, School of Allergy and Clinical Immunology, University of Messina, Italy
    Mediators Inflamm 2005:245-7. 2005
    ..These findings may explain, at least in part, the characteristic increase of memory cells in immunosenescence and the capacity of the immune system of centenarians to defend itself from infections through immune-inflammatory responses...
  14. doi IL-33 circulating serum levels are increased in patients with non-segmental generalized vitiligo
    Mario Vaccaro
    Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
    Arch Dermatol Res 308:527-30. 2016
    ..This study suggests a possible systemic role of IL-33 in the pathogenesis of vitiligo. Inhibiting IL-33 activity might be a novel therapeutic strategy in the treatment of autoimmune inflammatory disease, like vitiligo. ..
  15. ncbi Neurodegenerative Diseases: Might Citrus Flavonoids Play a Protective Role?
    Santa Cirmi
    Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Annunziata, Messina I 98168, Italy
    Molecules 21:. 2016
    ..This review may be used as scientific basis for the development of nutraceuticals, food supplements or complementary and alternative drugs to maintain and improve the neurophysiological status...
  16. doi Association between urticaria and virus infections: A systematic review
    Egidio Imbalzano
    Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
    Allergy Asthma Proc 37:18-22. 2016
    ..The lack of reported cases is probably due to the difficulty in establishing a cause-and-effect relationship. It is not possible to challenge the patient with an etiologic agent...
  17. doi NF-κB mediates the antiproliferative and proapoptotic effects of bergamot juice in HepG2 cells
    Nadia Ferlazzo
    Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy
    Life Sci 146:81-91. 2016
    ..In this study we investigated the molecular mechanisms underlying the antiproliferative activity of Citrus bergamia (bergamot) juice (BJ) in human hepatocellular carcinoma HepG2 cells...
  18. doi Possible link between history of hypersensitivity to a specific non-steroidal anti-inflammatory drug (NSAID) and positive results following challenge test to alternative NSAIDS
    Domenico Trombetta
    School of Farmacy, Department Farmaco Biologico, University of Messina, Messina, Italy
    Arzneimittelforschung 59:410-4. 2009
    ....
  19. ncbi Relationship between IL-18 and sICAM-1 serum levels in patients affected by coeliac disease: preliminary considerations
    Rosaria Alba Merendino
    Chair of Immunopathology, Department of Human Pathology, University of Messina Medical School, University Hospital G Martino, Via Centonze no 200, is 98, 98123, Messina, Italy
    Immunol Lett 85:257-60. 2003
    ..IL-18 enhances intercellular adhesion molecule-1 (ICAM-1) expression. We analyzed IL-18 serum levels in CD patients before and after gluten-free diet and the possible correlation with soluble ICAM-1 (sICAM-1) serum levels...
  20. ncbi Circulating Advanced Oxidation Protein Products as Oxidative Stress Biomarkers and Progression Mediators in Pathological Conditions Related to Inflammation and Immune Dysregulation
    Mariateresa Cristani
    School and Division of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
    Curr Med Chem 23:3862-3882. 2016
    ....
  21. doi Anti-Inflammatory Activity of Citrus bergamia Derivatives: Where Do We Stand?
    Nadia Ferlazzo
    Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina I 98168, Italy
    Molecules 21:. 2016
    ..Here, we present an overview of the anti-inflammatory properties of bergamot extracts that could represent the scientific basis for develop novel and alternative strategies to improve health status and attenuate inflammatory conditions. ..
  22. doi Effects of bergamot essential oil and its extractive fractions on SH-SY5Y human neuroblastoma cell growth
    Michele Navarra
    Department of Drug Sciences and Products for Health, University of Messina, Messina, Italy
    J Pharm Pharmacol 67:1042-53. 2015
    ..The goals were to investigate the mechanisms underlying the antiproliferative effects of bergamot essential oil (BEO) and to identify the compounds mainly responsible for its SH-SY5Y cells growth rate inhibition...
  23. doi Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products - Part 3: Mentha × piperita - Solanum dulcamara
    Gioacchino Calapai
    Department of Clinical and Experimental Medicine, University of Messina, Via Consolare Valeria, 98125, Messina, Italy
    Contact Dermatitis 74:131-44. 2016
    ..Part 3: Mentha × piperita L.-Solanum dulcamara L. ..
  24. doi Interleukin-10 involvement in exposure to low dose of benzene
    Giovanna Spatari
    Department of Social and Environmental Medicine, University of Messina, Messina, Italy
    Toxicol Ind Health 31:351-4. 2015
    ..To establish if serum levels of interleukin-10 (IL-10) in subjects exposed to benzene are connected with age, working years, and employment age...
  25. doi IL-33/IL-31 axis: a new pathological mechanisms for EGFR tyrosine kinase inhibitors-associated skin toxicity
    Sebastiano Gangemi
    School and Division of Allergy and Clinical Immunology, Department of Human Pathology, University Policlinic G Martino, Via Consolare Valeria 1, Messina, 90125, Italy Institute of Biomedicine and Molecular Immunology A Monroy IBIM Consiglio Nazionale delle Ricerche CNR, Via Ugo La Malfa 153, Palermo, 90146, Italy
    J Cell Biochem 114:2673-6. 2013
    ..This report, to the best of our knowledge, is the first work describing a possible involvement of IL-31/IL-33 axis in the pathogenesis of skin side effects related to EGFR-TK inhibitors treatment...
  26. doi Carbonyl group serum levels are associated with CD38 expression in patients with B chronic lymphocytic leukemia
    Caterina Musolino
    Division of Haematology, University of Messina, Messina, Italy
    Clin Biochem 44:1487-90. 2011
    ..To evaluate carbonyl groups (CG) serum levels in B-chronic lymphocytic leukemia (B-CLL) patients...
  27. doi Hypersensitivity to tranexamic acid: a wide spectrum of adverse reactions
    Selene Imbesi
    University of Messina, Messina, Italy
    Pharm World Sci 32:416-9. 2010
    ....
  28. pmc Malondialdehyde in benign prostate hypertrophy: a useful marker?
    Rosaria Alba Merendino
    Department of Human Pathology, University of Messina Medical School, University Hospital G Martino, Italy
    Mediators Inflamm 12:127-8. 2003
    ..In conclusion, we describe a previously unknown relationship between PSA and MDA as an index of inflammation and oxidative stress in BPH...
  29. pmc Chemopreventive Agents and Inhibitors of Cancer Hallmarks: May Citrus Offer New Perspectives?
    Santa Cirmi
    Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina I 98168, Italy
    Nutrients 8:. 2016
    ....
  30. ncbi Lethal Anaphylactic Reaction to Intravenous Gelatin in the Course of Surgery
    Elvira Ventura Spagnolo
    1Department of Biotechnology and Legal Medicine, Section of Legal Medicine, University of Palermo, Palermo, Italy 2Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy 3Operative Unit of Clinical Pharmacology, Azienda Ospedaliera Universitaria Policlinico G Martino, Messina, Italy 4Operative Unit of Allergy and Clinical Immunology, Azienda Ospedaliera Universitaria Policlinico G Martino, Messina, Italy 5Department of Biomedical Sciences and Morphological and Functional Images, Section of Morphological Forensic and Locomotor System, University of Messina, Messina, Italy and 6Institute of Clinical Physiology IFC, Consiglio Nazionale delle Ricerche CNR, Messina Unit, Messina, Italy
    Am J Ther 23:e1344-e1346. 2016
    ..It is currently considered a very rare event, but we believe that it represents an important signal suggesting for a critical surveillance comprising a complete evaluation of individual's allergic susceptibility...
  31. doi Matrix metalloproteinases and risk stratification in patients undergoing surgical revascularisation for critical limb ischaemia
    Giovanni De Caridi
    Department of Dentistry and Medical and Surgical Experimental Sciences, University of Messina, Messina, Italy
    Int Wound J 13:493-9. 2016
    ..MMP serum levels seem to be able to predict the clinical outcomes of patients with CLI. ..
  32. pmc Smoking, health and ageing
    Vittorio Nicita-Mauro
    Chair of Geriatrics and Gerontology, University of Messina, Messina, Italy
    Immun Ageing 5:10. 2008
    ..Hence, non-smokers can delay the appearance of diseases and of ageing process, so attaining longevity...
  33. doi Inflammaging and Anti-Inflammaging: The Role of Cytokines in Extreme Longevity
    Paola Lucia Minciullo
    Unit and School of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
    Arch Immunol Ther Exp (Warsz) 64:111-26. 2016
    ..We believe that if inflammaging is a key to understand aging, anti-inflammaging may be one of the secrets of longevity. ..
  34. doi Fatal Anaphylactic Shock Ceftriaxone-Induced in a 4-Year-Old Child
    Gioacchino Calapai
    From the Department of Clinical and Experimental Medicine, Section of Pharmacology Department of Clinical and Experimental Medicine, School and Unit of Allergy and Clinical Immunology, University of Messina, Messina Department of Biotechnology and Legal Medicine, Section of Legal Medicine, University of Palermo, Palermo Department of Drug Sciences and Health Products, University of Messina IRCCS Centro Neurolesi Bonino Pulejo, Messina and Institute of Biomedicine and MolecularImmunology A Monroy IBIM Consiglio Nazionale delle Ricerche CNR, Palermo, Italy
    Pediatr Emerg Care 32:32-3. 2016
    ....
  35. doi Oxidative Stress and Advanced Glycation End Products in Hashimoto's Thyroiditis
    Rosaria M Ruggeri
    1 Department of Clinical and Experimental Medicine, Division of Endocrinology, University of Messina, Messina, Italy
    Thyroid 26:504-11. 2016
    ..In addition, advanced glycation end products (AGEs) and advanced oxidation protein products (AOPPs)--compounds formed by the transformation of proteins--were evaluated as potential new markers of oxidative stress in this disease...
  36. doi Erythropoiesis-stimulating agents: dose and mortality risk
    Guido Bellinghieri
    Department of Clinical and Experimental Medicine, University of Messina, Italy
    J Ren Nutr 25:164-8. 2015
    ..ESAs and Hb serum levels were inversely correlated with mortality. Together, these findings suggest that ESAs dosage and Hb level may play a role through an independent manner or an interactive effect that adversely affects mortality. ..
  37. doi Review of Clinical Pharmacology of Aloe vera L. in the Treatment of Psoriasis
    Marco Miroddi
    Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
    Phytother Res 29:648-55. 2015
    ..Results on the effectiveness of Aloe vera are contradictory; our analysis reveals the presence of methodological gaps preventing to reach final conclusions...
  38. doi Clinical pharmacology of melatonin in the treatment of tinnitus: a review
    Marco Miroddi
    Department of Clinical and Experimental Medicine, University of Messina, Policlinico G Martino, Messina, Italy
    Eur J Clin Pharmacol 71:263-70. 2015
    ..Due to the fact that there is no satisfactory treatment for tinnitus, clinical research has explored new therapeutic approaches...
  39. doi Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products - part 2: Echinacea purpurea-Lavandula angustifolia
    Sebastiano Gangemi
    Department of Clinical and Experimental Medicine, University of Messina, Via Consolare Valeria, 98125 Messina, Italy Operative Unit of Allergy and Clinical Immunology, Azienda Ospedaliera Universitaria Policlinico G Martino, Via Consolare Valeria, 98125 Messina, Italy Institute of Clinical Physiology, IFC CNR, Messina Unit, Via Consolare Valeria, 98125 Messina, Italy
    Contact Dermatitis 72:193-205. 2015
    ..Part 2: Echinacea purpurea Moench-Lavandula angustifolia Mill. ..
  40. doi Montelukast-induced adverse drug reactions: a review of case reports in the literature
    Gioacchino Calapai
    School and Division of Allergology and Clinical Immunology, University of Messina, Messina, Italy
    Pharmacology 94:60-70. 2014
    ..Several clinical trials emphasized that montelukast can be considered a safe drug. However, recent evidence reconsidered the benefit/risk ratio of the use of montelukast for both paediatric and adult patients...
  41. ncbi Serum interleukin-23 (IL-23) is increased in Hashimoto's thyroiditis
    Rosaria Maddalena Ruggeri
    Unit of Endocrinology, Department of Clinical and Experimental Medicine, University of Messina, Italy
    Endocr J 61:359-63. 2014
    ..In conclusion, serum IL-23 is increased in euthyroid and untreated HT patients, as compared to healthy subjects. Our data suggest that IL-23 would play a role in the pathogenesis of HT...
  42. doi Healthy centenarians show high levels of circulating interleukin-22 (IL-22)
    Giorgio Basile
    School and Unit of Geriatrics, Department of Internal Medicine, University of Messina, AOU Policlinico, Via C Valeria n 1, 98125 Messina, Italy
    Arch Gerontol Geriatr 54:459-61. 2012
    ..The results of the present study show, for the first time, that there is an increase of IL-22 in healthy centenarians. This pro-inflammatory condition probably is protective against infection, promoting the longevity of these subjects...
  43. pmc Modification of interleukin-15 serum levels in workers exposed to chemotherapeutic agents
    Giovanna Spatari
    Department of Social and Environmental Medicine Section of Occupational Medicine, University of Messina, 98125 Messina, Italy
    Mediators Inflamm 2005:60-2. 2005
    ..If this increase representing an anticancer response remains to be established, these findings strengthen the idea of a therapeutic use of interleukin-15 in the field of cancer...
  44. ncbi Aging is characterized by a profound reduction in anti-inflammatory lipoxin A4 levels
    Sebastiano Gangemi
    Department of Human Pathology, University of Messina, Italy
    Exp Gerontol 40:612-4. 2005
    ..0026). We conclude that aging is associated with a switch in arachidonic acid metabolism that prevents formation of key 'stop signals' of the inflammatory reaction. This may contribute to promote the development of disease in elderly...
  45. ncbi Increased circulating Interleukin-18 levels in centenarians with no signs of vascular disease: another paradox of longevity?
    Sebastiano Gangemi
    Department of Human Pathology, University of Messina, 98125, Messina, Italy
    Exp Gerontol 38:669-72. 2003
    ..The present results indicate that quenching of IL-18 by IL-18BP may explain the apparent paradox of elevated serum IL-18 with no vascular signs in centenarians...
  46. doi Clinical Pharmacology of Citrus bergamia: A Systematic Review
    Carmen Mannucci
    Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy
    Phytother Res . 2016
    ..Further large-scale trials with rigorous design are required to define the role of C. bergamia in clinical practice. Copyright © 2016 John Wiley & Sons, Ltd...
  47. pmc Different clinical allergological features of Taenia solium infestation
    Paola Lucia Minciullo
    School and Division of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University Hospital G Martino, Messina, Italy
    Clin Mol Allergy 14:18. 2016
    ..Therefore, the association between Taenia infection and allergy needs to be thoroughly studied to better clarify if this association may really exist and which is the pathogenetic mechanism supported...
  48. doi Increased serum levels of interleukin-23 circulating in patients with non-segmental generalized vitiligo
    Mario Vaccaro
    Institute of Dermatology, University of Messina, Messina, Italy
    Int J Dermatol 54:672-4. 2015
    ..Vitiligo is a common progressive depigmentation of the skin due to selective destruction of melanocytes. Nowadays increasing evidences support the hypothesis of an autoimmune etiology...
  49. pmc Cytokine network involvement in subjects exposed to benzene
    Paola Lucia Minciullo
    Operative Unit of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy Policlinico Universitario, Via Consolare Valeria, 98125 Messina, Italy
    J Immunol Res 2014:937987. 2014
    ..The purpose of this review was to systematically analyze the published cases of cytokine effects on human benzene exposure, particularly hematotoxicity, and atopy, and on lungs. ..
  50. doi Oxidative stress in benign prostatic hyperplasia: a systematic review
    Paola Lucia Minciullo
    Operative Unit of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina, Italy
    Urol Int 94:249-54. 2015
    ..Prostate tissue damage and OS may lead to compensatory cellular proliferation with resulting hyperplastic growth...
  51. doi Challenge test to bisphosphonates in patients with hypersensitivity reactions to drugs
    Paola Lucia Minciullo
    Department of Clinical and Experimental Medicine, School and Division of Allergy and Clinical Immunology, University of Messina, Messina, Italy
    Allergol Immunopathol (Madr) 43:127-30. 2015
    ..Nitrogen-containing bisphosphonates have a favourable tolerability and safety profile, cutaneous reactions have been reported...
  52. doi Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products - part 1: Achillea millefolium-Curcuma longa
    Gioacchino Calapai
    Department of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy Operative Unit of Clinical Pharmacology, Azienda Ospedaliera Universitaria Policlinico G Martino, 98125 Messina, Italy
    Contact Dermatitis 71:1-12. 2014
    ..Part 1: Achillea millefolium L.-Curcuma longa L. ..
  53. doi Clinical significance of circulating interleukin-23 as a prognostic factor in breast cancer patients
    Sebastiano Gangemi
    School and Division of Allergy and Clinical Immunology, Department of Human Pathology, University Policlinic G Martino, Messina, Italy
    J Cell Biochem 113:2122-5. 2012
    ..However, further validations are needed in larger studies to better investigate the implications of IL-23 increase in these patients...
  54. ncbi Increased protein carbonyl groups in the serum of patients affected by thalassemia major
    Domenico Trombetta
    Pharmacobiology Department, School of Pharmacy, University of Messina, Messina, Italy
    Ann Hematol 85:520-2. 2006
    ..Our findings evidence that thalassemic patients suffer from protein oxidative stress; the possibility of a role for carbonyl stress in the progression and severity of the disease needs further investigation...
  55. pmc Involvement of fractalkine and macrophage inflammatory protein-1 alpha in moderate-severe depression
    Rosaria Alba Merendino
    Chair of Immunopathology, Department of Human Pathology, University of Messina, Italy
    Mediators Inflamm 13:205-7. 2004
    ..In conclusion, we describe a previously unknown involvement of FKN in the pathogenesis of MSD, suggesting that FKN may represent a target for a specific immune therapy of this disease...
  56. pmc Unmet diagnostic needs in contact oral mucosal allergies
    Paola Lucia Minciullo
    School and Division of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University Hospital G Martino, Messina, Italy
    Clin Mol Allergy 14:10. 2016
    ....
  57. pmc Mastocytosis and systemic sclerosis: a clinical association
    Gianluca Bagnato
    Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
    Clin Mol Allergy 14:13. 2016
    ..At the early stage of disease when organ involvement and extent of disease are emerging, mast cells may have some role, as implied by both symptoms and histologic evidence...
  58. doi Immature myeloid-derived suppressor cells: A bridge between inflammation and cancer (Review)
    Caterina Musolino
    Division of Hematology, Department of General Surgery, Pathological Anatomy and Oncology, University of Messina, Messina, Italy
    Oncol Rep . 2016
    ..Therapeutic approaches directed toward the manipulation of the MDSC population and their function may improve chemoimmune-enhancing therapy for advanced malignancies...
  59. pmc Association between HMGB1 and COPD: A Systematic Review
    Sebastiano Gangemi
    School and Operative Unit of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University Hospital G Martino, University of Messina, 98125 Messina, Italy
    Mediators Inflamm 2015:164913. 2015
    ..According to the results reported in the paper both inhibiting HMGB1 and its receptor (RAGE) and blocking neutrophils necrosis (inducted by cigarette smoking) could be the aim for further studies. ..
  60. ncbi Bergamot juice extract inhibits proliferation by inducing apoptosis in human colon cancer cells
    Giuseppa Visalli
    Department of Drug Sciences and Products for Health, University of Messina, Viale Annunziata, 98168, Messina, Italy
    Anticancer Agents Med Chem 14:1402-13. 2014
    ..Our study highlights the role of BJe as modulator of cell apoptosis in CRC cells and strengthens our previous hypothesis that the flavonoid fraction of bergamot juice may play a role as anti-cancer drug. ..
  61. ncbi Drug-induced TINU syndrome and genetic characterization
    Domenico Santoro
    Division of Nephrology, University of Messina, 98122 Messina, Italy
    Clin Nephrol 78:230-6. 2012
    ..This is the first report of TINU syndrome induced by flubiprofen intake. Our case emphasizes the importance of the association between drug exposure and strong susceptibility to TINU syndrome giving the molecular characterization...
  62. doi Pregnancy after azathioprine therapy for ulcerative colitis in a woman with autoimmune premature ovarian failure and Addison's disease: HLA haplotype characterization
    Francesco Ferrau
    Section of Endocrinology, Department of Medicine and Pharmacology, University of Messina, Messina, Italy
    Fertil Steril 95:2430.e15-7. 2011
    ..To present a case of fertility restored by azathioprine treatment in a woman with autoimmune premature ovarian failure, Addison's disease, and ulcerative colitis, and to study the genetic background of the three autoimmune diseases...
  63. ncbi Candesartan cilexetil-induced severe hepatotoxicity
    Giorgio Basile
    Division of Geriatric Medicine, Department of Internal Medicine, University of Messina, Messina, Italy
    J Clin Gastroenterol 36:273-5. 2003
    ..To our knowledge, this is the first description of severe hepatotoxicity associated with ductopenia caused by an adverse reaction to candesartan cilexetil...
  64. ncbi Eosinophilic fasciitis associated with autoimmune phenomena after bone marrow transplantation: report of two cases
    Paola L Minciullo
    Department of Human Pathology, School of Allergy and Clinical Immunology, University of Messina, Via Consolare Valeria, 98125 Messina, Italy
    Clin Rheumatol 25:80-2. 2006
    ..Moreover, we report for the first time the association of fasciitis with autoimmune phenomena after BMT. The correlation between the two entities is supported by remission of Hashimoto's thyroiditis after ECP treatment for fasciitis...
  65. doi Systematic review of clinical trials assessing pharmacological properties of Salvia species on memory, cognitive impairment and Alzheimer's disease
    Marco Miroddi
    Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
    CNS Neurosci Ther 20:485-95. 2014
    ..We believe that sage promising effects need further higher methodological standard clinical trials...
  66. doi Urticaria and bacterial infections
    Paola L Minciullo
    Operative Unit of Allergy and Clinical Immunology, Azienda Ospedaliera Universitaria Policlinico G Martino, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
    Allergy Asthma Proc 35:295-302. 2014
    ..Prospective studies and well-structured research are obviously needed to better clarify the real role of bacteria in the pathogenesis of urticaria and their relative prevalence...
  67. doi Interleukin-23 serum levels in patients affected by peripheral arterial disease
    Antonio David
    Department of Neurosciences, Psichiatric and Anesthesiological Sciences, University of Messina, Italy
    Clin Biochem 45:275-8. 2012
    ..To clarify whether interleukin (IL)-23 is involved in peripheral arterial disease (PAD)...
  68. pmc Interleukin-18 and CD30 serum levels in patients with moderate-severe depression
    Rosaria Alba Merendino
    Chair of Immunopathology, Department of Human Pathology, University of Messina Medical School, University Hospital G Martino, 98125 Messina, Italy
    Mediators Inflamm 11:265-7. 2002
    ..These data strengthen the hypothesis that MSD disease is associated with an inflammatory response, mainly T-cell-helper type 1, and suggest an important role for IL-18 in the pathophysiology of MSD...
  69. ncbi Fatal anaphylactic shock due to a dental impression material
    Sebastiano Gangemi
    School of Allergy and Clinical Immunology, Department of Human Pathology, University of Messina, Messina, Italy
    Int J Prosthodont 22:33-4. 2009
    ..To the authors' knowledge, dental impression materials, and alginate in particular, have not been reported previously as being a cause of anaphylaxis...
  70. ncbi Montelukast-induced generalized urticaria
    Paola L Minciullo
    Department of Human Pathology, Division and School of Allergy and Clinical Immunology, University of Messina, 98123 Messina, Italy
    Ann Pharmacother 38:999-1001. 2004
    ..To report a case of generalized urticaria induced by montelukast treatment...
  71. doi Bilateral cyclic cheek lesions related to premenstrual syndrome: a multifactorial pathogenesis?
    Paola Lucia Minciullo
    Department of Human Pathology, University of Messina, Italy
    Arch Gynecol Obstet 279:927-9. 2009
    ..Cheek biting is a chronic, usually innocuous, self-inflicted injury that often occurs as a parafunctional habit...
  72. ncbi Allergic contact dermatitis due to Zantedeschia aethiopica
    Paola Lucia Minciullo
    Division and School of Allergy and Clinical Immunology, Department of Human Pathology, University of Messina, 98123 Messina, Italy
    Contact Dermatitis 56:46-7. 2007
  73. pmc Serum levels of soluble CD30 in adult patients affected by atopic dermatitis and its relation to age, duration of disease and Scoring Atopic Dermatitis index
    Gabriele Di Lorenzo
    Dipartimento di Medicina Clinica e delle Patologie Emergenti, Universita degli Studi di Palermo, Italy
    Mediators Inflamm 12:123-5. 2003
    ..74; 95% CI for r (Fisher's z transformed)=-0.89 to -0.42; p=0.004). As demonstrated by the close correlation with age, duration of disease and SCORAD, serum levels of sCD30 appear to be an additional marker for the follow-up of AD...
  74. ncbi Modification of the content of plasma protein carbonyl groups in donors after granulocyte colony stimulating factor-induced stem cell mobilization
    Fortunato Morabito
    Bone Marrow Transplant Unit, Azienda Ospedaliera, Bianchi Melacrino Morelli, 89100 Reggio Calabria, Italy
    Transfus Apher Sci 33:141-6. 2005
    ..These findings may contribute to better understand the oxidative reactions following rHuG-CSF treatment and leukapheresis...