F Falcini

Summary

Affiliation: University of Florence
Country: Italy

Publications

  1. ncbi Reduction of bcl-2 in T cells during immunosuppressive therapy in patients with severe juvenile onset systemic lupus erythematosus
    F Falcini
    Rheumatology Unit, University of Florence, Florence, 50132, Italy
    Clin Immunol 93:59-64. 1999
  2. ncbi Acute febrile cholestasis as an inaugural manifestation of Kawasaki's disease
    F Falcini
    Rheumatology Unit, University of Florence, Florence, Italy
    Clin Exp Rheumatol 18:779-80. 2000
  3. ncbi Juvenile rheumatoid arthritis
    F Falcini
    Department of Pediatric Rheumatology Unit, University of Florence, Faculty of Medicine, Firenze, Italy
    Curr Opin Rheumatol 12:415-9. 2000
  4. ncbi Bcl-2, p53 and c-myc expression in juvenile dermatomyositis
    F Falcini
    Department of Paediatrics, University of Florence, Italy
    Clin Exp Rheumatol 18:643-6. 2000
  5. ncbi Coeliac disease in patients with Kawasaki disease. Is there a link?
    S Stagi
    Department of Paediatrics, Paediatric Rheumatology Unit, University of Florence, Florence, Italy
    Rheumatology (Oxford) 45:847-50. 2006
  6. ncbi Evidence for immune activation against oxidized lipoproteins in inactive phases of juvenile chronic arthritis
    G Simonini
    Department of Pediatrics, University of Florence, Italy
    J Rheumatol 28:198-203. 2001
  7. ncbi Macrophage migration inhibitory factor -173 polymorphism and risk of coronary alterations in children with Kawasaki disease
    G Simonini
    Department of Paediatrics, Rheumatology Unit, A Meyer Children s Hospital, Florence, Italy
    Clin Exp Rheumatol 27:1026-30. 2009
  8. doi Mycophenolate mofetil for the treatment of juvenile onset SLE: a multicenter study
    F Falcini
    Department of Biomedicine, Division of Rheumatology, Transition Unit, University of Florence, Florence, Italy
    Lupus 18:139-43. 2009
  9. doi Comparison of bone mass and quality determinants in adolescents and young adults with juvenile systemic lupus erythematosus (JSLE) and juvenile idiopathic arthritis (JIA)
    S Stagi
    Health Sciences Department, University of Florence, Anna Meyer Children s University Hospital, Florence, Italy
    Lupus 23:1392-406. 2014
  10. ncbi Kawasaki's disease in northern Italy: a multicenter retrospective study of 250 patients
    F Falcini
    Department of Paediatrics, University of Florence, Italy
    Clin Exp Rheumatol 20:421-6. 2002

Detail Information

Publications57

  1. ncbi Reduction of bcl-2 in T cells during immunosuppressive therapy in patients with severe juvenile onset systemic lupus erythematosus
    F Falcini
    Rheumatology Unit, University of Florence, Florence, 50132, Italy
    Clin Immunol 93:59-64. 1999
    ..Our data show a strong correlation between bcl-2 protein expression and disease activity and suggest an alteration of apoptotic regulation in JSLE patients...
  2. ncbi Acute febrile cholestasis as an inaugural manifestation of Kawasaki's disease
    F Falcini
    Rheumatology Unit, University of Florence, Florence, Italy
    Clin Exp Rheumatol 18:779-80. 2000
    ..We conclude that this syndrome should be suspected in any child with febrile cholestasis of unknown origin, in order that coronary involvement may be prevented by the administration of IVGG...
  3. ncbi Juvenile rheumatoid arthritis
    F Falcini
    Department of Pediatric Rheumatology Unit, University of Florence, Faculty of Medicine, Firenze, Italy
    Curr Opin Rheumatol 12:415-9. 2000
    ..For cases recalcitrant to conventional therapy autologous hemopoietic stem-cell transplantation has been attempted; the risks of this procedure must however be carefully balanced in individual patients...
  4. ncbi Bcl-2, p53 and c-myc expression in juvenile dermatomyositis
    F Falcini
    Department of Paediatrics, University of Florence, Italy
    Clin Exp Rheumatol 18:643-6. 2000
    ..To investigate p53, bcl-2 and c-myc expression in muscle biopsies from children affected with juvenile dermatomyositis (JDM) and to verify a possible dysregulation of programmed cell death in this autoimmune disease...
  5. ncbi Coeliac disease in patients with Kawasaki disease. Is there a link?
    S Stagi
    Department of Paediatrics, Paediatric Rheumatology Unit, University of Florence, Florence, Italy
    Rheumatology (Oxford) 45:847-50. 2006
    ..However, the occurrence of a second immunological disorder in a patient with a history of KD is rarely reported. We evaluated the presence of autoimmune thyroiditis and coeliac disease (CD) in patients with KD diagnosis...
  6. ncbi Evidence for immune activation against oxidized lipoproteins in inactive phases of juvenile chronic arthritis
    G Simonini
    Department of Pediatrics, University of Florence, Italy
    J Rheumatol 28:198-203. 2001
    ....
  7. ncbi Macrophage migration inhibitory factor -173 polymorphism and risk of coronary alterations in children with Kawasaki disease
    G Simonini
    Department of Paediatrics, Rheumatology Unit, A Meyer Children s Hospital, Florence, Italy
    Clin Exp Rheumatol 27:1026-30. 2009
    ..To investigate the possible relationship between MIF -173 polymorphism and susceptibility to, and severity of, Kawasaki disease (KD) in a cohort of Italian patients...
  8. doi Mycophenolate mofetil for the treatment of juvenile onset SLE: a multicenter study
    F Falcini
    Department of Biomedicine, Division of Rheumatology, Transition Unit, University of Florence, Florence, Italy
    Lupus 18:139-43. 2009
    ..With the limits of a retrospective study, MMF seems to be effective and safe for the treatment of juvenile-SLE, especially in patients with no renal involvement...
  9. doi Comparison of bone mass and quality determinants in adolescents and young adults with juvenile systemic lupus erythematosus (JSLE) and juvenile idiopathic arthritis (JIA)
    S Stagi
    Health Sciences Department, University of Florence, Anna Meyer Children s University Hospital, Florence, Italy
    Lupus 23:1392-406. 2014
    ..Few prospective data have been published on the comparison of bone density and quality in homogeneous groups of patients with juvenile systemic lupus erythematosus (JSLE) and juvenile idiopathic arthritis (JIA)...
  10. ncbi Kawasaki's disease in northern Italy: a multicenter retrospective study of 250 patients
    F Falcini
    Department of Paediatrics, University of Florence, Italy
    Clin Exp Rheumatol 20:421-6. 2002
    ....
  11. ncbi Evidence of subclinical intestinal inflammation by 99m technetium leukocyte scintigraphy in patients with HLA-B27 positive juvenile onset active spondyloarthropathy
    P Lionetti
    Department of Pediatrics, University of Florence, Italy
    J Rheumatol 27:1538-41. 2000
    ....
  12. doi Loss of efficacy during long-term infliximab therapy for sight-threatening childhood uveitis
    G Simonini
    Department of Paediatrics, Rheumatology Unit, Anna Meyer Children s Hospital and University of Florence, Italy
    Rheumatology (Oxford) 47:1510-4. 2008
    ..To describe efficacy and safety of infliximab in the treatment of childhood chronic uveitis during a long-term follow-up...
  13. doi Vitamin D levels in children, adolescents, and young adults with juvenile-onset systemic lupus erythematosus: a cross-sectional study
    S Stagi
    Health Sciences Department, University of Florence, Anna Meyer Children s University Hospital, Florence, Italy
    Lupus 23:1059-65. 2014
    ..Hypovitaminosis D is common in the general population. Although many studies on 25-hydroxyvitamin D (25(OH)D) are available on systemic lupus erythematosus (SLE), few data are reported in juvenile-onset SLE (JSLE) patients...
  14. ncbi Bilateral renal artery stenosis in Kawasaki disease: a report of two cases
    F Falcini
    Department of Paediatrics, Rheumatology Unit, University of Firenze, Italy
    Clin Exp Rheumatol 24:719-21. 2006
    ..Paediatricians should be alert to consider preceding KD as potential source of secondary hypertension in young infants, and raised blood pressure should be regarded as a life-threatening complication in all KD children...
  15. ncbi Severe abdominal involvement as the initial manifestation of cutaneous polyarteritis nodosa in a young girl
    F Falcini
    Department of Paediatrics, Rheumatology and Gastroenterology Unit, University of Florence, Italy
    Clin Exp Rheumatol 19:349-51. 2001
    ..Our case confirms that cutaneous PAN is often related to streptococcal infection, and suggests that ASO titers should be determined in children with vasculitides to ensure a timely diagnosis and treatment of the condition if present...
  16. ncbi Juvenile psoriatic arthritis and acquired sensorineural hearing loss in a teenager: is there an association?
    T Giani
    Department of Paediatrics, Rheumatology Unit, University of Florence, Florence, Italy
    Clin Exp Rheumatol 24:344-6. 2006
    ..The young age of our patient seems to suggest a genetic susceptibility to autoimmunity and supports the concept of associated autoimmune diseases...
  17. ncbi Systemic lupus erythematosus in the young: the importance of a transition clinic
    F Falcini
    Department of Paediatrics, Rheumatology Unit
    Lupus 16:613-7. 2007
    ..We report on our experience in a cohort of patients with juvenile SLE cared for at our transition clinic over last six years...
  18. ncbi Brain study using magnetic resonance imaging and proton MR spectroscopy in pediatric onset systemic lupus erythematosus
    M Mortilla
    Department of Radiology, A Meyer Children s Hospital, Florence, Italy
    Clin Exp Rheumatol 21:129-35. 2003
    ....
  19. pmc Circulating leptin levels in juvenile idiopathic arthritis: a marker of nutritional status?
    F Perfetto
    Department of Internal Medicine, Rheumatology Unit, University of Florence, 50139 Florence, Italy
    Ann Rheum Dis 64:149-52. 2005
    ..Weight loss is common in juvenile idiopathic arthritis (JIA) and has been positively correlated with an increase in the production of proinflammatory cytokines...
  20. pmc Prevalence and clinical significance of anti-cyclic citrullinated peptide antibodies in juvenile idiopathic arthritis
    T Avcin
    Department of Paediatrics, University of Ljubljana, Slovenia, Italy
    Ann Rheum Dis 61:608-11. 2002
    ..Antibodies against cyclic citrullinated peptide (anti-CCP) are considered to be specific for rheumatoid arthritis (RA)...
  21. ncbi Vascular and connective tissue diseases in the paediatric world
    F Falcini
    Department of Paediatrics, Rheumatology Unit, University of Florence, Firenze, Italy
    Lupus 13:77-84. 2004
    ....
  22. doi Cross-sectional and longitudinal evaluation of bone mass and quality in children and young adults with juvenile onset systemic lupus erythematosus (JSLE): role of bone mass determinants analyzed by DXA, PQCT and QUS
    S Stagi
    1Health s Sciences Department, University of Florence, Anna Meyer Children s University Hospital, Florence, Italy
    Lupus 23:57-68. 2014
    ..There are also few studies analyzing bone mass and quality determinants by using at the same time dual-energy X-ray absorptiometry (DXA), peripheral quantitative computed tomography (pQCT) and quantitative ultrasound (QUS)...
  23. pmc Sonographic evaluation of the temporomandibular joints in juvenile idiopathic arthritis()
    D Melchiorre
    Department of Internal Medicine, Section of Rheumatology, University of Florence, Italy
    J Ultrasound 13:34-7. 2010
    ..In oligoarticular forms of JIA, TMJ involvement is often asymptomatic and consequently overlooked. The aim of this study was to evaluate the presence of TMJ joint effusion (JE) by ultrasonography (US) in patients with early arthritis...
  24. ncbi Thyroid function, autoimmune thyroiditis and coeliac disease in juvenile idiopathic arthritis
    S Stagi
    Department of Paediatrics, University of Florence, Italy
    Rheumatology (Oxford) 44:517-20. 2005
    ..Our objective was to evaluate the thyroid function and the prevalence of antithyroid antibodies, autoimmune thyroiditis and coeliac disease in children with JIA...
  25. ncbi Mycoplasma pneumoniae: a possible trigger of kawasaki disease or a mere coincidental association? Report of the first four Italian cases
    E A Vitale
    Department of Pediatrics, Rheumatology Unit, University of Messina, Messina, Italy
    Minerva Pediatr 62:605-7. 2010
    ..We report four children with typical KD in whom a serological evidence of Mycoplasma pneumoniae infection was detected...
  26. ncbi MICA gene polymorphisms in an Italian paediatric series of juvenile Behçet disease
    P Picco
    Department of Paediatrics, G Gaslini Institute, Genoa, Italy
    Int J Mol Med 10:575-8. 2002
    ..This finding sheds light on the role of a receptor for MICA, named NKG2D, presented by natural killer cells, and CD8+, alphabetaT cells and gammadeltaT cells, usually localised in gut mucosa...
  27. ncbi Pulmonary involvement in juvenile dermatomyositis: a two-year longitudinal study
    S Trapani
    Department of Paediatrics, University of Florence, Italy
    Rheumatology (Oxford) 40:216-20. 2001
    ..CONCLUSIONS: We suggest that lung function should be evaluated at disease onset and regularly during follow-up, as pulmonary function tests can detect otherwise unpredictable pulmonary involvement...
  28. pmc A case-control study of cancers of the gastric cardia in Italy
    D Palli
    U O di Epidemiologia, Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Br J Cancer 65:263-6. 1992
    ..The authors discuss these findings in view of the rising incidence of adenocarcinomas of the cardia and lower oesophagus that has been reported in some western countries...
  29. ncbi Agreement estimate among three Italian cancer registries in the coding of multiple primary cancers
    E Buiatti
    Registro Tumori Toscano, Firenze, Italy
    Tumori 82:533-8. 1996
    ..The result on agreement with IARC-IACR rules is encouraging from the point of view of conducting a cooperative study among different registries on the incidence of MPs...
  30. ncbi Serum and synovial fluid concentration of vascular endothelial growth factor in juvenile idiopathic arthritides
    S Vignola
    Second Division of Paediatrics Rheumatology Unit, G Gaslini Scientific Institute for Children, Genoa, Italy
    Rheumatology (Oxford) 41:691-6. 2002
    ..To evaluate the role of vascular endothelial growth factor (VEGF) in the pathogenesis of local joint inflammation in juvenile idiopathic arthritis (JIA)...
  31. ncbi Prostate cancer in Italy before and during the 'PSA era': survival trend and prognostic determinants
    A Quaglia
    National Cancer Research Institute, Cancer Registry Unit, Largo Rosanna Benzi, n 10, 16132 Genova, Italy
    Eur J Cancer Prev 12:145-52. 2003
    ....
  32. doi Evaluation of service mammography screening impact in Italy. The contribution of hazard analysis
    Eugenio Paci
    Clinical and Descriptive Epidemiology Unit, CSPO, Research Institute of the Tuscany Region, Firenze, Italy
    Eur J Cancer 44:858-65. 2008
    ..96 in the [5-10] year time window, suggesting minimal or any length bias. Consistent with the results of randomised trials, these analyses of service screening data document a mortality reduction of 36% at 5-10 years after diagnosis...
  33. doi Influence of morphology on survival for non-Hodgkin lymphoma in Europe and the United States
    Milena Sant
    Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, I 20133, Milan, Italy
    Eur J Cancer 44:579-87. 2008
    ..Interpretation of marked variation in survival with morphology is complicated by classification inconsistencies. The completeness and standardisation of cancer registry morphology data needs to be improved...
  34. doi Survival in patients with uveal melanoma in Europe
    Gianni Virgili
    Department of Oto Neuro Ophthalmological Surgical Sciences, University of Florence, Viale Morgagni 85, Florence 50134, Italy
    Arch Ophthalmol 126:1413-8. 2008
    ..To estimate survival in patients in whom uveal melanoma was diagnosed between January 1, 1983, and December 31, 1994, in Europe...
  35. ncbi Performance indicators of organized cervical screening in Romagna (Italy)
    L Bucchi
    Romagna Cancer Registry, Medical Oncology Department, Luigi Pierantoni Hospital, 47100 Forli, Italy
    Eur J Cancer Prev 12:223-8. 2003
    ..35 (95% confidence interval (CI) 1.85-2.95). In conclusion, most early results of the programme were compatible with an acceptable performance...
  36. pmc Risk of cancer in persons with AIDS in Italy, 1985-1998
    L Dal Maso
    Servizio di Epidemiologia e Biostatistica, Centro di Riferimento Oncologico IRCCS, via Pedemontana Occ le 12, 33081 Aviano PN, Italy
    Br J Cancer 89:94-100. 2003
    ..4 and 2.3, respectively). This study confirmed increased SIRs for haemolymphopoietic neoplasms other than NHL in PWHA, although many-fold smaller than for NHL. An association with human papillomavirus-related cancers was also confirmed...
  37. ncbi Outcome of primary antiphospholipid syndrome in childhood
    M Gattorno
    Dipartimento di Pediatria, Universita di Genova, Pediatria II, Istituto G Gaslini, Italy
    Lupus 12:449-53. 2003
    ..In conclusion; our analysis suggests that some children who present with the features of primary APS may progress to develop SLE or lupus-like syndrome...
  38. ncbi Frequency and determinants of lymphadenectomy in endometrial carcinoma: a population-based study from northern Italy
    A Amadori
    Department of Obstetrics and Gynecology, Luigi Pierantoni Hospital, , Italy
    Ann Surg Oncol 8:723-8. 2001
    ....
  39. ncbi Relative and absolute cancer mortality of women in agriculture in northern Italy
    O Nanni
    Unit of Biostatistics and Clinical Trials, Istituto Oncologico Romagnolo, 47100 Forli, Italy
    Eur J Cancer Prev 14:337-44. 2005
    ..In conclusion, risk excesses previously reported were not confirmed. Agricultural workers qualified as a subset of the female population with atypical, favourable epidemiologic characteristics...
  40. ncbi Bone status over 1 yr of etanercept treatment in juvenile idiopathic arthritis
    G Simonini
    Department of Pediatrics Rheumatology Unit, Via Pico della Mirandola 24, 50132 Florence, Italy
    Rheumatology (Oxford) 44:777-80. 2005
    ..To evaluate bone mineral status over 1 yr of etanercept treatment in juvenile idiopathic arthritis (JIA)...
  41. ncbi Variations in the survival of adult cancer patients in Italy
    G Gatta
    Istituto Nazionale per la Cura e lo Studio dei Tumori, Milan, Italy
    Tumori 83:497-504. 1997
    ..The unfavorable trend with increasing age may be due to increasing difficulty in applying complete therapy protocols as general health declines, sometimes in relation to an advanced cancer stage at diagnosis...
  42. pmc Classic Kaposi's sarcoma in Italy, 1985-1998
    L Dal Maso
    Servizio di Epidemiologia e Biostatistica, Centro di Riferimento Oncologico IRCCS, via Pedemontana Occ le 12, 33081 Aviano, Italy
    Br J Cancer 92:188-93. 2005
    ..5 in individuals born in the same area, but 1.6 in individuals born in Southern Italy or in the Islands (rate ratio = 3.2) suggesting that KS-associated herpesvirus, the cause of KS, is acquired early in life...
  43. ncbi Lupus-like onset of recurrent Kawasaki disease in an adolescent boy
    S Marchetto
    Clin Exp Rheumatol 22:377. 2004
  44. ncbi Comparability issues within the ITACARE data base
    E Buiatti
    Tuscany Tumour Registry, Italy
    Tumori 83:25-32. 1997
    ..The variability of rules adopted by Italian registries may affect geographic survival differences only in a limited number of cancer sites, so that results should be interpreted with caution...
  45. ncbi [Kawasaki disease: clinical characteristics and cardiovascular involvement in a cohort of 121 patients]
    G B Calabri
    U O di Cardiologia Pediatrica, Ospedale A Meyer Via L Giordano no 13 Firenze
    Pediatr Med Chir 24:352-7; discussion 397-9. 2002
    ..The mean follow-up has been five years (range 6-138 months) and in no patient further cardiac manifestations have been observed; however, as little is known about the progression of vascular damage, a more protracted follow-up is needed...
  46. ncbi Levels of soluble CD27 in sera and synovial fluid and its expression on memory T cells in patients with juvenile idiopathic arthritides
    M Gattorno
    2nd Department of Pediatrics, G Gaslini Scientific Institute for Children and University of Genoa, Largo G Gaslini 5, 16147, Genoa, Italy
    Clin Exp Rheumatol 20:863-6. 2002
    ..The aim of the present study was to evaluate the levels of soluble CD27 in sera and synovial fluids, together with its expression on circulating and synovial fluid (SF) memory T cells, in children with JIA...
  47. ncbi The Italian version of the Childhood Health Assessment Questionnaire (CHAQ) and the Child Health Questionnaire (CHQ)
    N Ruperto
    Laboratorio di Informatica Medica, IRCCS S. Matteo, , Italy
    Clin Exp Rheumatol 19:S91-5. 2001
    ..In conclusion the Italian version of the CHAQ-CHQ are reliable, and valid tools for the functional, physical and psychosocial assessment of children with JIA...
  48. pmc Effectiveness of service screening: a case-control study to assess breast cancer mortality reduction
    D Puliti
    Clinical and Descriptive Epidemiology Unit, CSPO, Research Institute of the Tuscany Region, via San Salvi 12, Florence 50135, Italy
    Br J Cancer 99:423-7. 2008
    ..85). The introduction of breast cancer screening programmes in Italy is associated with a reduction in breast cancer mortality attributable to the additional impact of service screening over and above the background access to mammography...
  49. doi Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial
    Nicolino Ruperto
    IRCCS G Gaslini, PRINTO, Genoa, Italy
    Lancet 372:383-91. 2008
    ..We aimed to assess the safety and efficacy of abatacept, a selective T-cell costimulation modulator, in children with juvenile idiopathic arthritis who had failed previous treatments...
  50. ncbi A boy with bizarre hands mimicking an inflammatory chronic disease
    F Falcini
    Clin Exp Rheumatol 25:790-1. 2007
  51. pmc Multifocal lymphadenopathy associated with severe Kawasaki disease: a difficult diagnosis
    F Falcini
    Ann Rheum Dis 62:688-9. 2003
  52. pmc Mastectomy rates are decreasing in the era of service screening: a population-based study in Italy (1997-2001)
    M Zorzi
    Istituto Oncologico Veneto, Padova, Italy
    Br J Cancer 95:1265-8. 2006
    ..7% in the screening age group (50-69 years), and breast conserving surgery by 24.6%. Advanced cancer rates decreased by 19.4%, and mastectomy rates by 24.2%. Service screening did not increase mastectomy rates in the study population...
  53. ncbi Severe cutaneous manifestations in a child with refractory Kawasaki disease
    F Falcini
    Rheumatology (Oxford) 45:1444-5. 2006
  54. ncbi Atypical ductal hyperplasia of the breast: the controversial management of a borderline lesion: experience of 47 cases diagnosed at vacuum-assisted biopsy
    L Bedei
    Division of Oncology and Diagnostics, Morgagni Pierantoni Hospital, Via Forlanini 34, 47100 Forli, Italy
    Breast 15:196-202. 2006
    ....
  55. ncbi Thyroid function, autoimmune thyroiditis and coeliac disease in juvenile connective tissue diseases
    S Stagi
    Clin Exp Rheumatol 23:277. 2005
  56. ncbi Diagnosing Kawasaki syndrome: the need for a new clinical tool
    G Simonini
    Rheumatology (Oxford) 44:959-61. 2005
  57. ncbi Integrating self-referral for mammography into organised screening: results from an Italian experience
    L Bucchi
    Romagna Cancer Registry, Medical Oncology Department, Luigi Pierantoni Hospital, 47100 Forl, Italy
    J Med Screen 10:134-8. 2003
    ..To compare self-referred screenees with respondents to invitation for main performance indicators of mammography screening...