R Chiaramonte

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. ncbi request reprint Allele frequency of two intragenic microsatellite loci of SEL1L gene in Northern Italian population
    Raffaella Chiaramonte
    Department of Biomedical Sciences and Technologies, University of Milano, Segrate, Italy
    Mol Cell Biochem 232:159-61. 2002
  2. ncbi request reprint Targeting Notch as a therapeutic approach for human malignancies
    Platonova Natalia
    Department of Health Sciences, Universita degli Studi di Milano, Via A Di Rudini 8, I 20142, Milan, Italy
    Curr Pharm Des . 2016
  3. pmc The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias
    Luke B Hesson
    Department of Medical and Molecular Genetics, Institute of Biomedical Research, Medical School, University of Birmingham, Edgbaston, B15 2TT, UK
    Mol Cancer 8:42. 2009
  4. pmc Tracking human multiple myeloma xenografts in NOD-Rag-1/IL-2 receptor gamma chain-null mice with the novel biomarker AKAP-4
    Leonardo Mirandola
    Division of Hematology and Oncology, Texas Tech University Health Sciences Center and Southwest Cancer Treatment and Research Center, Lubbock, TX, USA
    BMC Cancer 11:394. 2011
  5. ncbi request reprint Oxidative stress signalling in the apoptosis of Jurkat T-lymphocytes
    R Chiaramonte
    Department of Biomedical Sciences and Technologies, University of Milano, LITA via Fratelli Cervi 93 20090 Segrate MI, Italy
    J Cell Biochem 82:437-44. 2001
  6. ncbi request reprint A wide role for NOTCH1 signaling in acute leukemia
    Raffaella Chiaramonte
    Department of Biomedical Science and Technology, University of Milano, LITA via Fratelli Cervi 93, 20090 Segrate, Milano, Italy
    Cancer Lett 219:113-20. 2005
  7. doi request reprint Anti-Notch treatment prevents multiple myeloma cells localization to the bone marrow via the chemokine system CXCR4/SDF-1
    L Mirandola
    Department of Health Sciences, Universita degli Studi di Milano, Milan, Italy
    Leukemia 27:1558-66. 2013
  8. ncbi request reprint Notch signal transduction is not regulated by SEL1L in leukaemia and lymphoma cells in culture
    Raffaella Chiaramonte
    Department of Biomedical Sciences and Technologies, University of Milano, LITA via Fratelli Cervi 93, 20090 Segrate, MI, Italy
    Anticancer Res 22:4211-4. 2002
  9. doi request reprint Notch pathway promotes ovarian cancer growth and migration via CXCR4/SDF1α chemokine system
    R Chiaramonte
    Department of Health Sciences, Universita degli Studi di Milano, Via A Di Rudini 8, I 20142, Milan, Italy
    Int J Biochem Cell Biol 66:134-40. 2015
  10. ncbi request reprint Differential regulation of Notch signal transduction in leukaemia and lymphoma cells in culture
    Raffaella Chiaramonte
    Department of Biomedical Sciences and Technologies, University of Milano, LITA via Fratelli Cervi 93 20090 Segrate MI, Italy
    J Cell Biochem 88:569-77. 2003

Collaborators

  • M Colombo
  • Gajanan V Sherbet
  • M Falleni
  • A Neri
  • P Riso
  • D Erba
  • D Capello
  • Platonova Natalia
  • L Mirandola
  • Leonardo Mirandola
  • Luke B Hesson
  • Elisabetta Calzavara
  • Paola Comi
  • Andrea Basile
  • Valentina Cecchinato
  • Basile Andrea
  • Palano Maria Teresa
  • Garavelli Silvia
  • Bignotto Monica
  • Neri Antonino
  • Colombo Michela
  • Chiaramonte Raffaella
  • Moschini Adriana
  • Lesma Elena
  • E Lazzari
  • Y Yu
  • M Chiriva-Internati
  • G Bulfamante
  • D G Berta
  • M Lancellotti
  • N Platonova
  • E Cobos
  • L Apicella
  • Maurizio Chiriva-Internati
  • Everardo Cobos
  • Constance M John
  • Marjorie R Jenkins
  • Yuefei Yu
  • Anna T Brini
  • Andrew D Chalmers
  • Mike Griffiths
  • Thomas L Dunwell
  • Farida Latif
  • Eamonn R Maher
  • Daniel Catchpoole
  • Wendy N Cooper
  • Daniela Cesana
  • Monica Nizzardo
  • Brunella Cristofaro

Detail Information

Publications13

  1. ncbi request reprint Allele frequency of two intragenic microsatellite loci of SEL1L gene in Northern Italian population
    Raffaella Chiaramonte
    Department of Biomedical Sciences and Technologies, University of Milano, Segrate, Italy
    Mol Cell Biochem 232:159-61. 2002
    ....
  2. ncbi request reprint Targeting Notch as a therapeutic approach for human malignancies
    Platonova Natalia
    Department of Health Sciences, Universita degli Studi di Milano, Via A Di Rudini 8, I 20142, Milan, Italy
    Curr Pharm Des . 2016
    ....
  3. pmc The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias
    Luke B Hesson
    Department of Medical and Molecular Genetics, Institute of Biomedical Research, Medical School, University of Birmingham, Edgbaston, B15 2TT, UK
    Mol Cancer 8:42. 2009
    ..We also determined the methylation status of CpG islands associated with RASSF1-10 in a series of childhood acute lymphocytic leukaemias (ALL) and normal blood and bone marrow samples...
  4. pmc Tracking human multiple myeloma xenografts in NOD-Rag-1/IL-2 receptor gamma chain-null mice with the novel biomarker AKAP-4
    Leonardo Mirandola
    Division of Hematology and Oncology, Texas Tech University Health Sciences Center and Southwest Cancer Treatment and Research Center, Lubbock, TX, USA
    BMC Cancer 11:394. 2011
    ..Continuous efforts are being made to develop innovative and more effective treatments. The preclinical evaluation of new therapies relies on the use of murine models of the disease...
  5. ncbi request reprint Oxidative stress signalling in the apoptosis of Jurkat T-lymphocytes
    R Chiaramonte
    Department of Biomedical Sciences and Technologies, University of Milano, LITA via Fratelli Cervi 93 20090 Segrate MI, Italy
    J Cell Biochem 82:437-44. 2001
    ..No modulation of the antioxidant enzymes, catalase, Cu/Zn superoxide dismutase and glutathione peroxidase was detectable...
  6. ncbi request reprint A wide role for NOTCH1 signaling in acute leukemia
    Raffaella Chiaramonte
    Department of Biomedical Science and Technology, University of Milano, LITA via Fratelli Cervi 93, 20090 Segrate, Milano, Italy
    Cancer Lett 219:113-20. 2005
    ..AML primary samples show high levels of JAGGED1 expression despite the low NOTCH1 pathway activation, consistent with an autonomous JAGGED1 signaling in myeloid leukemogenesis...
  7. doi request reprint Anti-Notch treatment prevents multiple myeloma cells localization to the bone marrow via the chemokine system CXCR4/SDF-1
    L Mirandola
    Department of Health Sciences, Universita degli Studi di Milano, Milan, Italy
    Leukemia 27:1558-66. 2013
    ..This is the first evidence that a Notch-targeted approach effectively prevents MM cell migration, proliferation and resistance to apoptosis by reducing CXCR4 and SDF-1 levels. ..
  8. ncbi request reprint Notch signal transduction is not regulated by SEL1L in leukaemia and lymphoma cells in culture
    Raffaella Chiaramonte
    Department of Biomedical Sciences and Technologies, University of Milano, LITA via Fratelli Cervi 93, 20090 Segrate, MI, Italy
    Anticancer Res 22:4211-4. 2002
    ..No genomic alterations affecting SEL1L were detected either in the lymphoma or T-ALL cell lines tested. Taken together the present findings do not support the postulated negative regulatory role for SEL1L in Notch signalling...
  9. doi request reprint Notch pathway promotes ovarian cancer growth and migration via CXCR4/SDF1α chemokine system
    R Chiaramonte
    Department of Health Sciences, Universita degli Studi di Milano, Via A Di Rudini 8, I 20142, Milan, Italy
    Int J Biochem Cell Biol 66:134-40. 2015
    ....
  10. ncbi request reprint Differential regulation of Notch signal transduction in leukaemia and lymphoma cells in culture
    Raffaella Chiaramonte
    Department of Biomedical Sciences and Technologies, University of Milano, LITA via Fratelli Cervi 93 20090 Segrate MI, Italy
    J Cell Biochem 88:569-77. 2003
    ..This is the first demonstration of a distinction between B-lymphomas and T-cell leukaemias in the functioning of the Notch-signalling pathway. This might be related to their pathogenesis...
  11. doi request reprint Notch-directed microenvironment reprogramming in myeloma: a single path to multiple outcomes
    M Colombo
    Department of Health Science, Universita degli Studi di Milano, Milan, Italy
    Leukemia 27:1009-18. 2013
    ..Finally, we will present recent findings concerning the arguments for or against a therapy addressed to Notch signaling inhibition in the cure of multiple myeloma...
  12. ncbi request reprint Resveratrol-induced apoptosis in human T-cell acute lymphoblastic leukaemia MOLT-4 cells
    Valentina Cecchinato
    Department of Biomedical Science and Technology, University of Milano, Italy
    Biochem Pharmacol 74:1568-74. 2007
    ..Here, we have identified potential signalling pathways influenced by RES and this could lead to the identification of the targets of RES-induced apoptosis and growth control...
  13. ncbi request reprint Reciprocal regulation of Notch and PI3K/Akt signalling in T-ALL cells in vitro
    Elisabetta Calzavara
    Department of Biomedical Sciences and Technologies, University of Milano, LITA, via Fratelli Cevi 93, 20090 Segrate Mi, Italy
    J Cell Biochem 103:1405-12. 2008
    ....