Annalisa Castagna

Summary

Affiliation: University of Verona
Country: Italy

Publications

  1. doi request reprint Hepcidin assay in serum by SELDI-TOF-MS and other approaches
    Annalisa Castagna
    Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    J Proteomics 73:527-36. 2010
  2. pmc Serum levels of the hepcidin-20 isoform in a large general population: the Val Borbera study
    Natascia Campostrini
    Department of Medicine, Section of Internal Medicine, University of Verona, Italy
    J Proteomics 76:28-35. 2012
  3. doi request reprint Urinary prostasin in normotensive individuals: correlation with the aldosterone to renin ratio and urinary sodium
    Oliviero Olivieri
    Department of Medicine, Unit of Internal Medicine B, University of Verona, Verona, Italy
    Hypertens Res 36:528-33. 2013
  4. doi request reprint Murine macrophages response to iron
    Rita Polati
    University of Verona, Department of Biotechnology, Strada Le Grazie 15, 37134 Verona, Italy
    J Proteomics 76:10-27. 2012
  5. doi request reprint Hepcidin is not useful as a biomarker for iron needs in haemodialysis patients on maintenance erythropoiesis-stimulating agents
    Nicola Tessitore
    Hemodialysis Unit Ospedale Policlinico, Division of Nephrology, University of Verona, Verona, Italy
    Nephrol Dial Transplant 25:3996-4002. 2010
  6. ncbi request reprint Critical survey of quantitative proteomics in two-dimensional electrophoretic approaches
    Pier Giorgio Righetti
    Department of Agricultural and Industrial Biotechnologies, University of Verona, Verona, Italy
    J Chromatogr A 1051:3-17. 2004
  7. doi request reprint Circadian exosomal expression of renal thiazide-sensitive NaCl cotransporter (NCC) and prostasin in healthy individuals
    Annalisa Castagna
    Department of Medicine, Section of Internal Medicine, University of Verona, Verona, Italy
    Proteomics Clin Appl 9:623-9. 2015
  8. pmc High resolution preparation of monocyte-derived macrophages (MDM) protein fractions for clinical proteomics
    Rita Polati
    University of Verona, Department of Biotechnology, Italy
    Proteome Sci 7:4. 2009
  9. pmc Evaluation of hepcidin isoforms in hemodialysis patients by a proteomic approach based on SELDI-TOF MS
    Natascia Campostrini
    Department of Medicine, University of Verona, 37134 Verona, Italy
    J Biomed Biotechnol 2010:329646. 2010
  10. ncbi request reprint Increased urinary excretion of the epithelial Na channel activator prostasin in patients with primary aldosteronism
    Francesca Pizzolo
    aDepartment of Medicine, Division of Internal Medicine, University of Verona bDepartment of Pathology and Diagnostics, Section Clinical Chemistry, University of Verona, Verona, Italy
    J Hypertens . 2016

Collaborators

Detail Information

Publications32

  1. doi request reprint Hepcidin assay in serum by SELDI-TOF-MS and other approaches
    Annalisa Castagna
    Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    J Proteomics 73:527-36. 2010
    ..Here we review recent results obtained with this technique, as well as with other Mass Spectrometry-based and immunological methods...
  2. pmc Serum levels of the hepcidin-20 isoform in a large general population: the Val Borbera study
    Natascia Campostrini
    Department of Medicine, Section of Internal Medicine, University of Verona, Italy
    J Proteomics 76:28-35. 2012
    ..This article is part of a Special Issue entitled: Integrated omics...
  3. doi request reprint Urinary prostasin in normotensive individuals: correlation with the aldosterone to renin ratio and urinary sodium
    Oliviero Olivieri
    Department of Medicine, Unit of Internal Medicine B, University of Verona, Verona, Italy
    Hypertens Res 36:528-33. 2013
    ..In conclusion, urinary prostasin correlates with the ARR, and it is physiologically modulated by natriuresis in normotensive individuals...
  4. doi request reprint Murine macrophages response to iron
    Rita Polati
    University of Verona, Department of Biotechnology, Strada Le Grazie 15, 37134 Verona, Italy
    J Proteomics 76:10-27. 2012
    ..This article is part of a Special Issue entitled: Integrated omics...
  5. doi request reprint Hepcidin is not useful as a biomarker for iron needs in haemodialysis patients on maintenance erythropoiesis-stimulating agents
    Nicola Tessitore
    Hemodialysis Unit Ospedale Policlinico, Division of Nephrology, University of Verona, Verona, Italy
    Nephrol Dial Transplant 25:3996-4002. 2010
    ..It has been suggested that hepcidin may be useful as a tool for managing iron therapy in haemodialysis (HD) patients on erythropoiesis-stimulating agents (ESA)...
  6. ncbi request reprint Critical survey of quantitative proteomics in two-dimensional electrophoretic approaches
    Pier Giorgio Righetti
    Department of Agricultural and Industrial Biotechnologies, University of Verona, Verona, Italy
    J Chromatogr A 1051:3-17. 2004
    ..The latter reagent achieves 100% efficiency coupled to 100% specificity. The advantages and limitations of the various protocols are discussed...
  7. doi request reprint Circadian exosomal expression of renal thiazide-sensitive NaCl cotransporter (NCC) and prostasin in healthy individuals
    Annalisa Castagna
    Department of Medicine, Section of Internal Medicine, University of Verona, Verona, Italy
    Proteomics Clin Appl 9:623-9. 2015
    ..We analyzed in urinary exosomes the intraday variations of NCC and prostasin expression and the association with electrolytes and water balance parameters...
  8. pmc High resolution preparation of monocyte-derived macrophages (MDM) protein fractions for clinical proteomics
    Rita Polati
    University of Verona, Department of Biotechnology, Italy
    Proteome Sci 7:4. 2009
    ..To this regard, proteomic analysis, is one of the most powerful tools for the elucidation of the molecular mechanisms, in terms of changes in protein expression levels...
  9. pmc Evaluation of hepcidin isoforms in hemodialysis patients by a proteomic approach based on SELDI-TOF MS
    Natascia Campostrini
    Department of Medicine, University of Verona, 37134 Verona, Italy
    J Biomed Biotechnol 2010:329646. 2010
    ..Measurement of hepcidin isoforms through MS-based techniques can be a useful tool for better understanding of their biological role in hemodialysis patients and other clinical conditions...
  10. ncbi request reprint Increased urinary excretion of the epithelial Na channel activator prostasin in patients with primary aldosteronism
    Francesca Pizzolo
    aDepartment of Medicine, Division of Internal Medicine, University of Verona bDepartment of Pathology and Diagnostics, Section Clinical Chemistry, University of Verona, Verona, Italy
    J Hypertens . 2016
    ....
  11. pmc Reduced serum hepcidin levels in patients with chronic hepatitis C
    Domenico Girelli
    Department of Clinical and Experimental Medicine, University of Verona, Policlinico G B Rossi, Verona, Italy
    J Hepatol 51:845-52. 2009
    ....
  12. doi request reprint Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma
    Oliviero Olivieri
    Department of Medicine, Unit of Internal Medicine, University of Verona, P le L A Scuro10, Verona, Italy
    Mol Biosyst 10:1281-9. 2014
    ..In conclusion urine SB3 concentrations are physiologically much lower in males than in females. Hypertensive women, affected by APA, present urinary SB3 concentrations significantly higher than women affected by BAH. ..
  13. ncbi request reprint Proteomic approaches for studying chemoresistance in cancer
    Pier Giorgio Righetti
    University of Verona, Department of Industrial and Agricultural Biotechnologies, Laboratory of Proteome Science, Strada Le Grazie 15, Verona, Italy
    Expert Rev Proteomics 2:215-28. 2005
    ....
  14. ncbi request reprint The proteome: anno Domini 2002
    Pier Giorgio Righetti
    Department of Agricultural and Industrial Biotechnologies, Faculty of Sciences, University of Verona, Verona, Italy
    Clin Chem Lab Med 41:425-38. 2003
    ..Some general conclusions are drawn on proteome analysis and we end this review by trying to decode the glass ball of the aruspex and answer the question: "Quo vadis, proteome"?..
  15. pmc Clinical, pathological, and molecular correlates in ferroportin disease: a study of two novel mutations
    Domenico Girelli
    Department of Clinical and Experimental Medicine, University of Verona, Policlinico GB Rossi, Verona, Italy
    J Hepatol 49:664-71. 2008
    ..This appears to reflect functional heterogeneity of Fpn mutants, with loss-of-function generally resulting in the M type...
  16. doi request reprint NT-proBNP, a useful tool in hypertensive patients undergoing a diagnostic evaluation for primary aldosteronism
    Francesca Pizzolo
    Division of Internal Medicine, Department of Medicine, University of Verona, pzz le Scuro, 37134, Verona, Italy
    Endocrine 45:479-86. 2014
    ..NT-proBNP and gender are predictors of a positive PA confirmatory test. These findings highlight the possibility of using NT-proBNP to identify which patients with a high ARR should receive a complete PA diagnostic evaluation...
  17. doi request reprint Epigenetic control of 11 beta-hydroxysteroid dehydrogenase 2 gene promoter is related to human hypertension
    Simonetta Friso
    Department of Clinical and Experimental Medicine, University of Verona School of Medicine, Verona, Italy
    Atherosclerosis 199:323-7. 2008
    ..Little is known, however, of human HSD11B2 epigenetic control and its relationship with the onset of hypertension...
  18. doi request reprint Monocyte/macrophage proteomics: recent findings and biomedical applications
    Annalisa Castagna
    Department of Medicine, Unit of Internal Medicine, University of Verona, Policlinico G B Rossi, Piazzale L A Scuro 10, Verona, Italy
    Expert Rev Proteomics 9:201-15. 2012
    ..Here, we review the application of such techniques to the study of monocytes/macrophages, and summarize some results potentially relevant to two paradigmatic conditions - atherosclerosis and disorders of iron metabolism...
  19. doi request reprint Measurement of urinary hepcidin levels by SELDI-TOF-MS in HFE-hemochromatosis
    Claudia Bozzini
    Department of Clinical and Experimental Medicine, University of Verona, Policlinico G B Rossi, 37134 Verona, Italy
    Blood Cells Mol Dis 40:347-52. 2008
    ..This study measured urinary hepcidin levels by SELDI-TOF-MS in a large group of HH patients at diagnosis and during treatment, including both C282Y homozygous and C282Y/H63D compound heterozygotes...
  20. doi request reprint Female urinary proteomics: New insight into exogenous and physiological hormone-dependent changes
    Annalisa Castagna
    Department of Medicine, Unit of Internal Medicine, University of Verona, Italy
    Proteomics Clin Appl 5:343-53. 2011
    ..Clinical parameters and renin-angiotensin-aldosterone system (RAAS) components were also investigated, on the basis of the well-known relation linking sex female hormones and renin and aldosterone levels...
  21. ncbi request reprint Exploring the hidden human urinary proteome via ligand library beads
    Annalisa Castagna
    Department of Clinical and Experimental Medicine, Unit of Internal Medicine, University of Verona, Italy
    J Proteome Res 4:1917-30. 2005
    ..By comparing our data with those reported to the present, an additional 251 proteins could be added to the list, thus bringing the total unique gene products so far identified in human urines to ca. 800 species...
  22. pmc Increased serum hepcidin levels in subjects with the metabolic syndrome: a population study
    Nicola Martinelli
    Department of Medicine, University of Verona, Verona, Italy
    PLoS ONE 7:e48250. 2012
    ..Due to recently discovered pleiotropic effects of hepcidin, this may worsen insulin resistance and contribute to the cardiovascular complications of MetS...
  23. ncbi request reprint Prefractionation techniques in proteome analysis: the mining tools of the third millennium
    Pier Giorgio Righetti
    University of Verona, Department of Industrial and Agricultural Biotechnolgies, Verona, Italy
    Electrophoresis 26:297-319. 2005
    ..It is felt that this panoply of methods could offer a strong step forward in "mining below the tip of the iceberg" for detecting the "unseen proteome"...
  24. ncbi request reprint A proteomic approach to cisplatin resistance in the cervix squamous cell carcinoma cell line A431
    Annalisa Castagna
    University of Verona, Department of Agricultural and Industrial Biotechnologies, Verona, Italy
    Proteomics 4:3246-67. 2004
    ..This pattern of response, also observed in parental cells, could reflect an intrinsic resistance of this tumor type...
  25. pmc Surface plasmon resonance based on molecularly imprinted nanoparticles for the picomolar detection of the iron regulating hormone Hepcidin-25
    Lucia Cenci
    Department of Biotechnology, University of Verona, Strada Le Grazie 15, 37134, Verona, Italy
    J Nanobiotechnology 13:51. 2015
    ..Biotinylated MIP NPs were immobilized to NeutrAvidin™ SPR sensor chip. The response of the MIP NP sensor to Hepcidin-25 was studied...
  26. doi request reprint Hormone-dependent changes in female urinary proteome
    Annalisa Castagna
    Department of Medicine, Unit of Internal Medicine, University of Verona, Verona, Italy
    Adv Exp Med Biol 845:103-20. 2015
    ....
  27. ncbi request reprint How to bring the "unseen" proteome to the limelight via electrophoretic pre-fractionation techniques
    Pier Giorgio Righetti
    Department of Industrial and Agricultural Biotechnologies, University of Verona, Verona, Italy
    Biosci Rep 25:3-17. 2005
    ..Other free-flow systems, as well as miniaturized chambers, are also described...
  28. ncbi request reprint Prefractionation techniques in proteome analysis
    Pier Giorgio Righetti
    Department of Agricultural and Industrial Biotechnologies, University of Verona, Strada Le Grazie No 15, I 37134 Verona, Italy
    Proteomics 3:1397-407. 2003
    ..It is felt that this panoply of methods could offer a strong step forward in "mining below the tip of the iceberg" for detecting the "unseen proteome"...
  29. ncbi request reprint Proteome analysis in the clinical chemistry laboratory: myth or reality?
    Pier Giorgio Righetti
    Department of Agricultural and Industrial Biotechnologies, University of Verona, Strada Le Grazie No 15, Verona 37134, Italy
    Clin Chim Acta 357:123-39. 2005
    ....
  30. ncbi request reprint Urinary prostasin: a candidate marker of epithelial sodium channel activation in humans
    Oliviero Olivieri
    Department of Clinical and Experimental Medicine, University of Verona, Italy
    Hypertension 46:683-8. 2005
    ....
  31. ncbi request reprint Recent trends in proteome analysis
    Pier Giorgio Righetti
    University of Verona, Verona, Italy
    Adv Chromatogr 42:269-321. 2003
  32. ncbi request reprint Comparative two-dimensional mapping of prion protein isoforms in human cerebrospinal fluid and central nervous system
    Annalisa Castagna
    Department of Agricultural and Industrial Biotechnologies, University of Verona, Italy
    Electrophoresis 23:339-46. 2002
    ..It also shows the incredible microheterogeneity of such isoforms (ca. 60 spots!), as revealed in 2-D mapping, as opposed to 3-4 main zones by mono-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE)...