Gaetano Caramori

Summary

Affiliation: University of Ferrara
Country: Italy

Publications

  1. pmc Nuclear localisation of p65 in sputum macrophages but not in sputum neutrophils during COPD exacerbations
    G Caramori
    Research Center on Asthma and COPD and Occupational Medicine, University of Ferrara, Italy
    Thorax 58:348-51. 2003
  2. ncbi request reprint Molecular mechanisms of respiratory virus-induced asthma and COPD exacerbations and pneumonia
    Gaetano Caramori
    Centro di Ricerca su Asma e BPCO, University of Ferrara, Italy
    Curr Med Chem 13:2267-90. 2006
  3. ncbi request reprint Ectopic thymoma simulating a pericardial cyst
    G Caramori
    Dipartimento di Medicina Clinica e Sperimentale, Sezione di Malattie dell Apparato Respiratorio, University of Ferrara, Italy
    Monaldi Arch Chest Dis 63:230-3. 2005
  4. ncbi request reprint Asthma is not a common cause of severe chronic respiratory failure in non-smokers: ALOT study
    G Caramori
    Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Italy
    Monaldi Arch Chest Dis 63:84-7. 2005
  5. ncbi request reprint Underuse of spirometry by general practitioners for the diagnosis of COPD in Italy
    G Caramori
    Centro di Ricerca su Asma e BPCO, University of Ferrara, Italy
    Monaldi Arch Chest Dis 63:6-12. 2005
  6. ncbi request reprint Mucin expression in peripheral airways of patients with chronic obstructive pulmonary disease
    G Caramori
    Centro di Ricerca su Asma e BPCO, University of Ferrara, Ferrara, Italy
    Histopathology 45:477-84. 2004
  7. ncbi request reprint Targeting Th2 cells in asthmatic airways
    Gaetano Caramori
    Dipartimento di Medicina Clinica e Sperimentale, Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Italy
    Curr Drug Targets Inflamm Allergy 3:243-55. 2004
  8. ncbi request reprint Transcription factors in asthma and COPD
    Gaetano Caramori
    Dipartimento di Medicina Clinica e Sperimentale, Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Via Savonarola 9, Italy
    IDrugs 7:764-70. 2004
  9. ncbi request reprint Degree of control of physician-diagnosed asthma and COPD in Italy
    G Caramori
    Centro di Ricerca su Asma e BPCO, Via Savonarola 9, University of Ferrara, 44100 Ferrara, Italy
    Monaldi Arch Chest Dis 67:15-22. 2007
  10. pmc Induction and regulation of matrix metalloproteinase-12 in human airway smooth muscle cells
    Shaoping Xie
    Experimental Studies, National Heart and Lung Institute, Imperial College, London, UK
    Respir Res 6:148. 2005

Collaborators

Detail Information

Publications37

  1. pmc Nuclear localisation of p65 in sputum macrophages but not in sputum neutrophils during COPD exacerbations
    G Caramori
    Research Center on Asthma and COPD and Occupational Medicine, University of Ferrara, Italy
    Thorax 58:348-51. 2003
    ..Nuclear localisation of p65 is a signal of nuclear factor-kappaB (NF-kappaB) activation. A study was undertaken to evaluate whether NF-kappaB activation is modified in sputum cells during COPD exacerbations...
  2. ncbi request reprint Molecular mechanisms of respiratory virus-induced asthma and COPD exacerbations and pneumonia
    Gaetano Caramori
    Centro di Ricerca su Asma e BPCO, University of Ferrara, Italy
    Curr Med Chem 13:2267-90. 2006
    ..Clearly this is an exciting new area of ongoing research with promising therapeutic potential...
  3. ncbi request reprint Ectopic thymoma simulating a pericardial cyst
    G Caramori
    Dipartimento di Medicina Clinica e Sperimentale, Sezione di Malattie dell Apparato Respiratorio, University of Ferrara, Italy
    Monaldi Arch Chest Dis 63:230-3. 2005
    ..The diagnosis of thymoma was made only after histopathological examination of the surgically re-sected lesion...
  4. ncbi request reprint Asthma is not a common cause of severe chronic respiratory failure in non-smokers: ALOT study
    G Caramori
    Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Italy
    Monaldi Arch Chest Dis 63:84-7. 2005
    ..The aim of our study (Asthma and Long-term Oxygen Therapy, "ALOT") was to investigate the prevalence of non-smoking asthmatics in patients on LTOT in a multi-centre, cross-sectional study...
  5. ncbi request reprint Underuse of spirometry by general practitioners for the diagnosis of COPD in Italy
    G Caramori
    Centro di Ricerca su Asma e BPCO, University of Ferrara, Italy
    Monaldi Arch Chest Dis 63:6-12. 2005
    ..In collaboration with the Italian Academy of General practitioners (SIMG) we have investigated the degree of use of spirometry to establish the diagnosis of COPD in Italy...
  6. ncbi request reprint Mucin expression in peripheral airways of patients with chronic obstructive pulmonary disease
    G Caramori
    Centro di Ricerca su Asma e BPCO, University of Ferrara, Ferrara, Italy
    Histopathology 45:477-84. 2004
    ..To study the expression of mucins in peripheral airways in patients with chronic obstructive pulmonary disease (COPD)...
  7. ncbi request reprint Targeting Th2 cells in asthmatic airways
    Gaetano Caramori
    Dipartimento di Medicina Clinica e Sperimentale, Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Italy
    Curr Drug Targets Inflamm Allergy 3:243-55. 2004
    ..Some of these new Th2-oriented strategies may in the future not only control symptoms, but also potentially prevent or cure the disease...
  8. ncbi request reprint Transcription factors in asthma and COPD
    Gaetano Caramori
    Dipartimento di Medicina Clinica e Sperimentale, Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Via Savonarola 9, Italy
    IDrugs 7:764-70. 2004
    ..Several new compounds based on interactions with specific transcription factors or their activation pathways are now in development for the treatment of asthma and COPD...
  9. ncbi request reprint Degree of control of physician-diagnosed asthma and COPD in Italy
    G Caramori
    Centro di Ricerca su Asma e BPCO, Via Savonarola 9, University of Ferrara, 44100 Ferrara, Italy
    Monaldi Arch Chest Dis 67:15-22. 2007
    ..Currently, precise estimates of these parameters are not available in literature...
  10. pmc Induction and regulation of matrix metalloproteinase-12 in human airway smooth muscle cells
    Shaoping Xie
    Experimental Studies, National Heart and Lung Institute, Imperial College, London, UK
    Respir Res 6:148. 2005
    ..We investigated whether human airway smooth muscle cells could express and secrete MMP-12, thereby participating in the pathogenesis of airway inflammatory diseases...
  11. doi request reprint Rhinovirus infection causes steroid resistance in airway epithelium through nuclear factor κB and c-Jun N-terminal kinase activation
    Alberto Papi
    Section of Respiratory Diseases, Department of Medical Sciences, University of Ferrara, Ferrara, Italy Electronic address
    J Allergy Clin Immunol 132:1075-1085.e6. 2013
    ..Although inhaled glucocorticoids are the mainstays of asthma treatment, they are poorly effective at treating and preventing virus-induced asthma exacerbations. The major viruses precipitating asthma exacerbations are rhinoviruses...
  12. doi request reprint Rescue treatment in asthma. More than as-needed bronchodilation
    Alberto Papi
    Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Via Savonarola 9, 44100 Ferrara, Italy
    Chest 135:1628-33. 2009
    ..In the future it might even be possible to control asthma entirely with PRN combination inhalers without maintenance therapy, at least in patients with less severe disease...
  13. doi request reprint Fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease: 5-year follow-up
    Marco Contoli
    Research Centre on Asthma and COPD, Department of Clinical and Experimental Medicine, University of Ferrara, Ferrara, Italy
    J Allergy Clin Immunol 125:830-7. 2010
    ..Both smokers and patients with asthma can experience fixed airflow obstruction, which is associated with distinctive patterns of airway pathology. The influence of fixed airflow obstruction on the prognosis of these patients is unknown...
  14. doi request reprint Oxidative/nitrosative stress selectively altered A(2B) adenosine receptors in chronic obstructive pulmonary disease
    Katia Varani
    Department of Clinical and Experimental Medicine, Pharmacology Unit, University of Ferrara, Via Fossato di Mortara 17 19, 44100 Ferrara, Italy
    FASEB J 24:1192-204. 2010
    ..Triggiani, M., Hansel, T., Leung, E., MacLennan, S., Barnes, P. J., Fan Chung, K., Adcock, I., Papi, A., Borea, P. A. Oxidative/nitrosative stress selectively altered A(2B) adenosine receptors in chronic obstructive pulmonary disease...
  15. doi request reprint A role for phosphoinositol 3-kinase delta in the impairment of glucocorticoid responsiveness in patients with chronic obstructive pulmonary disease
    John A Marwick
    Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Ferrara, Italy
    J Allergy Clin Immunol 125:1146-53. 2010
    ..This reduction in glucocorticoid sensitivity might be due to an oxidant-mediated increase in phosphoinositol 3-kinase (PI3K) delta signaling...
  16. doi request reprint MUC5AC expression is increased in bronchial submucosal glands of stable COPD patients
    Gaetano Caramori
    Centro di Ricerca su Asma e BPCO, University of Ferrara, Via Savonarola 9, Ferrara 44121, Italy
    Histopathology 55:321-31. 2009
    ..The aim was to investigate gland size and MUC5AC and MUC5B expression in bronchial rings from smokers with COPD compared with control groups...
  17. doi request reprint Asthma: a chronic infectious disease?
    Gaetano Caramori
    Section of Respiratory Diseases, Department of Medical Sciences, Centro per lo Studio delle Malattie Infiammatorie Croniche delle Vie Aeree e Patologie Fumo Correlate dell Apparato Respiratorio, University of Ferrara, Via Savonarola 9, 44121, Ferrara, Italy
    Clin Chest Med 33:473-84. 2012
    ..The role of bacterial infections in chronic asthma remains unclear. This article reviews the available evidence indicating that asthma may be considered as a chronic infectious disease...
  18. doi request reprint Unbalanced oxidant-induced DNA damage and repair in COPD: a link towards lung cancer
    Gaetano Caramori
    Centro di Ricerca su Asma e BPCO, University of Ferrara, Via Savonarola, 9, Ferrara 44100, Italy
    Thorax 66:521-7. 2011
    ..Chronic obstructive pulmonary disease (COPD) is characterised by oxidative stress and increased risk of lung carcinoma. Oxidative stress causes DNA damage which can be repaired by DNA-dependent protein kinase complex...
  19. ncbi request reprint A human rhinovirus model of chronic obstructive pulmonary disease exacerbations
    Marco Contoli
    Department of Clinical and Experimental Medicine, Research Center on Asthma and COPD, University of Ferrara, Ferrara, Italy
    Contrib Microbiol 14:101-12. 2007
    ..In this chapter we will focus on the role of viral infections in COPD exacerbations and will discuss preliminary reports regarding the development of this human model of virus-induced COPD exacerbation...
  20. doi request reprint Clinical definition of COPD exacerbations and classification of their severity
    Gaetano Caramori
    Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Ferrara, Italy
    South Med J 102:277-82. 2009
    ..There is a need for greater investment in research on COPD exacerbations in order to promote a better understanding of COPD exacerbations...
  21. doi request reprint Role of transcription factors in the pathogenesis of asthma and COPD
    Gaetano Caramori
    Centro Interdipartimentale per lo Studio delle Malattie Infiammatorie delle Vie Aeree e Patologie Fumo correlate CEMICEF formerly named Centro di Ricerca su Asma e BPCO, Sezione di Malattie dell Apparato Respiratorio, Universita di Ferrara, Ferrara, Italy
    Cell Commun Adhes 20:21-40. 2013
    ....
  22. pmc Nasal inflammation and its response to local glucocorticoid regular treatment in patients with persistent non-allergic rhinitis: a pilot study
    Donatella Poletti
    ORL, Azienda USL Ferrara, Italy, Sezione di Scienze Otorinolaringoiatriche e Fisica Medica, Departimento di Scienze Biomediche e Chirurgico Specialistiche, University of Ferrara, Ferrara, Italy
    J Inflamm (Lond) 13:26. 2016
    ..The pathogenesis of non-allergic rhinitis (NAR) is still largely unknown. Furthermore, it is unclear whether there is a correlation between the effect of nasal glucocorticoids on nasal inflammation and on nasal symptoms and quality of life...
  23. pmc Pathophysiology of viral-induced exacerbations of COPD
    Alfredo Potena
    Unita Operativa di Fisiopatologia Respiratoria, Azienda Ospedaliera Universitaria Arcispedale S Anna, Ferrara, Italy
    Int J Chron Obstruct Pulmon Dis 2:477-83. 2007
    ..In this review we will focus our attention on the relationship between common respiratory viral infections and the molecular and inflammatory mechanisms that lead to COPD exacerbation...
  24. doi request reprint [Role of stem cells in the pathogenesis of chronic obstructive pulmonary disease and of pulmonary emphysema]
    Gaetano Caramori
    Dipartimento di Medicina, Universita di Ferrara, Italy
    Recenti Prog Med 103:31-40. 2012
    ..Moreover, the potential side effects of the stem cell therapy are often underestimated. We should not ignore that some of the most deadly neoplasms are arising from stem cells...
  25. pmc Immune response to Mycobacterium tuberculosis infection in the parietal pleura of patients with tuberculous pleurisy
    Gaetano Caramori
    Section of Respiratory Diseases, University of Ferrara, Ferrara, Italy
    PLoS ONE 6:e22637. 2011
    ..Elevated CD3, CD4, CCR4 and Th17 cells and decreased mast cells and GATA-3+ cells in the parietal pleura distinguish patients with untreated tuberculous pleurisy from those with nonspecific pleuritis...
  26. doi request reprint Mechanisms involved in lung cancer development in COPD
    Gaetano Caramori
    Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Ferrara, Italy
    Int J Biochem Cell Biol 43:1030-44. 2011
    ....
  27. ncbi request reprint [Treatment of bronchial asthma in adults. Current advances]
    Gaetano Caramori
    Dipartimento di Medicina Clinica e Sperimentale, Centro di Ricerca su Asma e BPCO, Universita, Ferrara
    Recenti Prog Med 100:171-9. 2009
    ..Considering its efficacy and safety the current pharmacological treatment of asthma will probably remain unchanged for the next 10 years...
  28. pmc COPD immunopathology
    Gaetano Caramori
    Centro Interdipartimentale per lo Studio delle Malattie Infiammatorie delle Vie Aeree e Patologie Fumo correlate CEMICEF formerly named Centro di Ricerca su Asma e BPCO, Sezione di Medicina Interna e Cardiorespiratoria, Universita di Ferrara, Via Savonarola 9, 44121, Ferrara, Italy
    Semin Immunopathol 38:497-515. 2016
    ..This review summarises and discusses the immunopathology of COPD patients, of different severity, compared with control smokers with normal lung function. ..
  29. ncbi request reprint Models of infection and exacerbations in COPD
    Alberto Papi
    Department of Clinical and Experimental Medicine, Research Centre on Asthma and COPD, University of Ferrara, Ferrara, Italy
    Curr Opin Pharmacol 7:259-65. 2007
    ..The model will give us the opportunity to highlight key inflammatory mediators representing possible therapeutic targets for the development of novel drugs able to treat and prevent acute episodes in COPD...
  30. pmc New drugs targeting Th2 lymphocytes in asthma
    Gaetano Caramori
    Dipartimento di Medicina Clinica e Sperimentale, Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Ferrara, Italy
    J Occup Med Toxicol 3:S6. 2008
    ..Some of these new Th2-oriented strategies may in the future not only control symptoms and modify the natural course of asthma, but also potentially prevent or cure the disease...
  31. doi request reprint Molecular pathogenesis of cigarette smoking-induced stable COPD
    Gaetano Caramori
    Centro Interdipartimentale per lo Studio delle Malattie Infiammatorie delle Vie Aeree e Patologie Fumo correlate CEMICEF, Sezione di Medicina Interna e Cardiorespiratoria, Universita di Ferrara, Ferrara, Italy
    Ann N Y Acad Sci 1340:55-64. 2015
    ..Furthermore, glucocorticoids drugs already in clinical use act through their own transcription factor, the glucocorticoid receptor, to control the expression of inflammatory and anti-inflammatory genes...
  32. pmc Cytokine inhibition in the treatment of COPD
    Gaetano Caramori
    Dipartimento di Scienze Mediche, Centro Interdipartimentale per lo Studio delle Malattie Infiammatorie delle vie Aeree e Patologie Fumo correlate CEMICEF formerly Centro di Ricerca su Asma e BPCO, Sezione di Medicina Interna e Cardiorespiratoria, Universita di Ferrara, Ferrara, Italy
    Int J Chron Obstruct Pulmon Dis 9:397-412. 2014
    ..Specific groups of COPD patients should be targeted with specific anticytokine therapy if there is evidence of high expression of that cytokine and there are features of the clinical expression of COPD that will respond. ..
  33. pmc Profile of fluticasone furoate/vilanterol dry powder inhaler combination therapy as a potential treatment for COPD
    Gaetano Caramori
    Centro Interdipartimentale per lo Studio delle Malattie Infiammatorie delle vie Aeree e Patologie Fumo correlate CEMICEF formerly Centro di Ricerca su Asma e BPCO, Sezione di Medicina Interna e Cardiorespiratoria, Universita di Ferrara, Ferrara, Italy
    Int J Chron Obstruct Pulmon Dis 9:249-56. 2014
    ....
  34. ncbi request reprint Gene-environment interactions in the development of chronic obstructive pulmonary disease
    Gaetano Caramori
    Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Ferrara, Italy
    Curr Opin Allergy Clin Immunol 6:323-8. 2006
    ..Recent studies have begun to shed some light on these gene-environment interactions...
  35. ncbi request reprint Is there a difference between chronic airway inflammation in chronic severe asthma and chronic obstructive pulmonary disease?
    Gaetano Caramori
    Department of Clinical and Experimental Medicine, Centre of Research on Asthma and COPD, University of Ferrara, Ferrara, Italy
    Curr Opin Allergy Clin Immunol 5:77-83. 2005
    ....
  36. ncbi request reprint Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease
    Katia Varani
    Department of Clinical and Experimental Medicine, Pharmacology Unit, Via Fossato di Mortara 17 19, 44100 Ferrara, Italy
    Am J Respir Crit Care Med 173:398-406. 2006
    ..Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of mortality worldwide. Adenosine is an inflammatory regulator that acts through four distinct receptors to mediate pro- and antiinflammatory effects...
  37. pmc Primary Pulmonary Epithelioid Hemangioendothelioma: A Rare Cause of PET-Negative Pulmonary Nodules
    Riccardo Cazzuffi
    Sezione di Malattie dell Apparato Respiratorio, Dipartimento di Medicina Clinica e Sperimentale, Universita di Ferrara, Italy
    Case Report Med 2011:262674. 2011
    ..At the 18F-fluorodeoxyglucose positron emission tomography, these nodules were negative. The histopathological diagnosis was made on a pulmonary wedge resection (performed during video-thoracoscopic surgery)...