C Betterle

Summary

Affiliation: University of Padova
Country: Italy

Publications

  1. doi Diagnosis and classification of autoimmune parathyroid disease
    Corrado Betterle
    Endocrine Unit, Department of Medicine, University of Padova, Via Ospedale Civile, 105 35128 Padova, Italy Electronic address
    Autoimmun Rev 13:417-22. 2014
  2. doi Autoimmune-polyendocrinopathy-candidiasis-ectodermal-dystrophy in Calabria: clinical, immunological and genetic patterns
    C Betterle
    Endocrine Unit, Department of Medicine, University of Padova, Padova, Italy
    J Endocrinol Invest 35:877-81. 2012
  3. doi Autoimmune Addison's disease
    Corrado Betterle
    Clinical Immunology, Endocrine Unit, Department of Medical and Surgical Sciences, University of Padova, Via Ospedale Civile 105, Padua, Italy
    Endocr Dev 20:161-72. 2011
  4. ncbi Update on autoimmune polyendocrine syndromes (APS)
    Corrado Betterle
    Clinical Immunology and Allergology, Department of Medical and Surgical Sciences, University of Padua, Padua, Italy
    Acta Biomed 74:9-33. 2003
  5. pmc Autoimmune polyglandular syndrome Type 2: the tip of an iceberg?
    C Betterle
    Unit of Endocrinology, Department of Medical and Surgical Sciences, University of Padua, Italy
    Clin Exp Immunol 137:225-33. 2004
  6. ncbi Pancreatic autoantibodies in Italian patients with newly diagnosed type 1 diabetes mellitus over the age of 20 years
    C Betterle
    Division of Endocrinology, Department of Medical and Surgical Sciences, University of Padua, Italy
    Acta Diabetol 43:79-83. 2006
  7. ncbi Assessment of adrenocortical function and autoantibodies in a baby born to a mother with autoimmune polyglandular syndrome Type 2
    C Betterle
    Department of Medical and Surgical Sciences, Unit of Endocrinology, University of Padova, Padova Hospital, Padova, Italy
    J Endocrinol Invest 27:618-21. 2004
  8. ncbi Parathyroid and autoimmunity
    C Betterle
    Endocrine Unit, Department of Medical and Surgical Sciences University of Padova, Padova, Italy
    Ann Endocrinol (Paris) 67:147-54. 2006
  9. ncbi Adrenal cortex autoantibodies in subjects with normal adrenal function
    Corrado Betterle
    Endocrine Unit, Department of Medical and Surgical Sciences, University of Padova, Via Ospedale Civile 105, 35100 Padova, Italy
    Best Pract Res Clin Endocrinol Metab 19:85-99. 2005
  10. ncbi Celiac disease in North Italian patients with autoimmune Addison's disease
    Corrado Betterle
    Division of Endocrinology, Department of Medical and Surgical Sciences, University of Padua Medical School, Via Ospedale Civile 105, 35100 Padua, Italy
    Eur J Endocrinol 154:275-9. 2006

Detail Information

Publications62

  1. doi Diagnosis and classification of autoimmune parathyroid disease
    Corrado Betterle
    Endocrine Unit, Department of Medicine, University of Padova, Via Ospedale Civile, 105 35128 Padova, Italy Electronic address
    Autoimmun Rev 13:417-22. 2014
    ..We also describe the clinical characteristics of HP and design a diagnostic algorithm for autoimmune HP. ..
  2. doi Autoimmune-polyendocrinopathy-candidiasis-ectodermal-dystrophy in Calabria: clinical, immunological and genetic patterns
    C Betterle
    Endocrine Unit, Department of Medicine, University of Padova, Padova, Italy
    J Endocrinol Invest 35:877-81. 2012
    ..Diagnosis requires the presence of at least two of three major clinical features: chronic mucocutaneous candidiasis, chronic hypoparathyroidism, and Addison's disease...
  3. doi Autoimmune Addison's disease
    Corrado Betterle
    Clinical Immunology, Endocrine Unit, Department of Medical and Surgical Sciences, University of Padova, Via Ospedale Civile 105, Padua, Italy
    Endocr Dev 20:161-72. 2011
    ..Replacement therapy with gluco-and mineralocorticoids is life-saving for patients with chronic adrenal insufficiency...
  4. ncbi Update on autoimmune polyendocrine syndromes (APS)
    Corrado Betterle
    Clinical Immunology and Allergology, Department of Medical and Surgical Sciences, University of Padua, Padua, Italy
    Acta Biomed 74:9-33. 2003
    ....
  5. pmc Autoimmune polyglandular syndrome Type 2: the tip of an iceberg?
    C Betterle
    Unit of Endocrinology, Department of Medical and Surgical Sciences, University of Padua, Italy
    Clin Exp Immunol 137:225-33. 2004
    ..Historical, clinical, genetic, and immunological aspects of Type 2 APS are reviewed. Furthermore, data on 146 personal cases of Type 2 APS are also reported...
  6. ncbi Pancreatic autoantibodies in Italian patients with newly diagnosed type 1 diabetes mellitus over the age of 20 years
    C Betterle
    Division of Endocrinology, Department of Medical and Surgical Sciences, University of Padua, Italy
    Acta Diabetol 43:79-83. 2006
    ..The best cost/benefit combination is provided by coupling the detection of GADA and ICA...
  7. ncbi Assessment of adrenocortical function and autoantibodies in a baby born to a mother with autoimmune polyglandular syndrome Type 2
    C Betterle
    Department of Medical and Surgical Sciences, Unit of Endocrinology, University of Padova, Padova Hospital, Padova, Italy
    J Endocrinol Invest 27:618-21. 2004
    ..These data suggest that the presence of adrenal autoantibodies in serum alone is not a sufficient cause for the development of autoimmune adrenalitis...
  8. ncbi Parathyroid and autoimmunity
    C Betterle
    Endocrine Unit, Department of Medical and Surgical Sciences University of Padova, Padova, Italy
    Ann Endocrinol (Paris) 67:147-54. 2006
    ..Furthermore, data on 71 Italian patients with chronic hypoparathyroidism are presented...
  9. ncbi Adrenal cortex autoantibodies in subjects with normal adrenal function
    Corrado Betterle
    Endocrine Unit, Department of Medical and Surgical Sciences, University of Padova, Via Ospedale Civile 105, 35100 Padova, Italy
    Best Pract Res Clin Endocrinol Metab 19:85-99. 2005
    ..Patients with different risk scores need to be monitored at different time intervals, and those at high risk need to be strictly monitored and are the ideal subjects for future prevention trials...
  10. ncbi Celiac disease in North Italian patients with autoimmune Addison's disease
    Corrado Betterle
    Division of Endocrinology, Department of Medical and Surgical Sciences, University of Padua Medical School, Via Ospedale Civile 105, 35100 Padua, Italy
    Eur J Endocrinol 154:275-9. 2006
    ..IgA deficiency is frequent in patients with other autoimmune diseases, but data concerning AAD are still unavailable...
  11. ncbi The number of markers of pancreatic autoimmunity is proportional to the risk for type 1 diabetes mellitus in Italian and English patients with organ-specific autoimmune diseases
    C Betterle
    Department of Medical and Surgical Sciences, University of Padova, Italy
    Ann N Y Acad Sci 958:276-80. 2002
    ..The risk for type 1 DM increased proportionally with the number of diabetes-related antibodies, which were also related to the presence of genetic markers of disease susceptibility...
  12. ncbi Pancreatic autoantibodies in Italian patients with newly diagnosed type 1 diabetes mellitus under the age of 20 years
    C Betterle
    Department of Medical and Surgical Sciences, University of Padova, Italy
    Ann N Y Acad Sci 958:271-5. 2002
    ....
  13. ncbi Autoimmune adrenal insufficiency and autoimmune polyendocrine syndromes: autoantibodies, autoantigens, and their applicability in diagnosis and disease prediction
    Corrado Betterle
    Chair of Clinical Immunology and Allergy, Department of Medical and Surgical Sciences, University of Padova, I 35128, Padova, Italy
    Endocr Rev 23:327-64. 2002
    ..An original flow chart for the diagnosis of AD has been proposed...
  14. ncbi Adrenal-cortex autoantibodies and steroid-producing cells autoantibodies in patients with Addison's disease: comparison of immunofluorescence and immunoprecipitation assays
    C Betterle
    Department of Clinical Immunology and Allergy, Istituto di Semeiotica Medica, University of Padova, Italy
    J Clin Endocrinol Metab 84:618-22. 1999
    ....
  15. ncbi Antigenic differences between neurological and diabetic patients with anti-glutamic acid decarboxylase antibodies
    M Vianello
    Department of Neurology and Psychiatry Sciences Second Clinic, University of Padua, Italy
    Eur J Neurol 12:294-9. 2005
    ..A working proposal is therefore that type 1 diabetic patients with unusual neurological symptoms should be tested for GADAb both by RIA and IHC...
  16. ncbi Autoantibodies to steroidogenic enzymes in patients with premature ovarian failure with and without Addison's disease
    C Dal Pra
    Chair of Clinical Immunology and Allergy, Division of Endocrinology, Department of Medical and Surgical Sciences, University of Padua, Via Ospedale 105, Padua, Italy
    Eur J Endocrinol 148:565-70. 2003
    ....
  17. doi Premature ovarian failure in patients with autoimmune Addison's disease: clinical, genetic, and immunological evaluation
    G Reato
    Endocrine Unit, Department of Medical and Surgical Sciences, University of Padua School of Medicin, Padua Italy
    J Clin Endocrinol Metab 96:E1255-61. 2011
    ....
  18. ncbi Autoimmunity against pancreatic islets and other tissues before and after interferon-alpha therapy in patients with hepatitis C virus chronic infection
    C Betterle
    Department of Medical and Surgical Sciences, University of Padua, Italy
    Diabetes Care 23:1177-81. 2000
    ..The aim of the study was to investigate the prevalence of clinical and latent autoimmune diseases in Italian patients with hepatitis C virus (HCV) chronic infection before and after treatment with interferon-alpha (IFN-alpha)...
  19. ncbi Autoimmunity in isolated Addison's disease and in polyglandular autoimmune diseases type 1, 2 and 4
    C Betterle
    Clinical Immunology and Allergy, Department of Medical and Surgical Sciences, University of Padova, Via Ospedale Civile 105, 35128 Padova, Italy
    Ann Endocrinol (Paris) 62:193-201. 2001
    ..In some patients, steroid-producing cell autoantibodies were also present and correlated with gonadal failure and they recognize of 17alpha-hydroxylase or P450 side chain cleavage enzymes as target antigens...
  20. ncbi Clinical, subclinical and potential autoimmune diseases in an Italian population of children with coeliac disease
    G Guariso
    Department of Pediatrics, University of Padua, Padua, Italy
    Aliment Pharmacol Ther 26:1409-17. 2007
    ....
  21. pmc Gonadal function in males with autoimmune Addison's disease and autoantibodies to steroidogenic enzymes
    M Dalla Costa
    Endocrine Unit, University of Padova, Padova, UK
    Clin Exp Immunol 176:373-9. 2014
    ..This study suggests that the diagnostic value of SEAbs in males with AAD differs compared to females, and this may be related to the immunoprivileged status of the testis...
  22. ncbi Lymphocyte subsets and cytokines in women with gestational diabetes mellitus and their newborn
    A Lapolla
    Metabolic Disorders Section, Department of Medical and Surgical Sciences, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Cytokine 31:280-7. 2005
    ..In conclusion, GDM women and their newborn have lymphocyte subset impairments, which are more important in patients positive for autoantibodies and/or treated with insulin...
  23. doi Celiac disease in North Italian patients with autoimmune thyroid diseases
    Aglaura Cinzia Spadaccino
    Division of Endocrinology, Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    Autoimmunity 41:116-21. 2008
    ..An IgA deficiency is the most frequent immunodeficiency in humans and, in general, high frequency of this disorder was demonstrated in those with autoimmune diseases...
  24. ncbi Is hepatitis C virus a risk factor for thyroid autoimmunity?
    A Floreani
    Department of Surgical and Gastroenterological Sciences, University of Padova, Italy
    J Viral Hepat 13:272-7. 2006
    ....
  25. doi Evaluation of the autoimmune regulator (AIRE) gene mutations in a cohort of Italian patients with autoimmune-polyendocrinopathy-candidiasis-ectodermal-dystrophy (APECED) and in their relatives
    Sara Cervato
    Division of Endocrinology, Department of Medical and Surgical Sciences, University of Padua, Padua, Italy
    Clin Endocrinol (Oxf) 70:421-8. 2009
    ..Design AIRE mutations were determined by DNA sequencing in all subjects. Patients were tested for clinical autoimmune or non-autoimmune diseases, or for organ and non-organ specific autoantibodies...
  26. doi Tryptophan hydroxylase autoantibodies as markers of a distinct autoimmune gastrointestinal component of autoimmune polyendocrine syndrome type 1
    R Scarpa
    Department of Medicine DIMED, University of Padua, Padua 35128, Italy
    J Clin Endocrinol Metab 98:704-12. 2013
    ..Serotonin plays a critical role in enteric function and its peripheral blood levels reflect serotonin release from the gastrointestinal tract...
  27. doi Autoimmune polyendocrinopathy-candidiasis-ectodermal-dystrophy (APECED) in Sicily: confirmation that R203X is the peculiar AIRE gene mutation
    C Giordano
    Endocrine Unit, Department of Biomedical Internal and Specialist Medicine, Palermo University, Palermo, Italy
    J Endocrinol Invest 35:384-8. 2012
    ..Accepted criteria for diagnosis require the presence of at least 2 of 3 major clinical features: chronic mucocutaneous candidiasis (CMC), chronic hypoparathyroidism (CH), and Addison's disease (AD)...
  28. ncbi Some patients with antiphospholipid syndrome express hitherto undescribed antibodies to cardiolipin-binding proteins
    P Rampazzo
    Department of Clinical and Experimental Medicine, Thrombosis Center, University of Padova, Italy
    Thromb Haemost 85:57-62. 2001
    ..In conclusion, some patients with APS harbor circulating antibodies to other CL-binding proteins which might be useful to further characterize these patients...
  29. ncbi Helicobacter pylori infection and gastric autoimmune diseases: is there a link?
    Fabio Presotto
    Department of Medical and Surgical Sciences, University of Padua School of Medicine, Padua, Italy
    Helicobacter 8:578-84. 2003
    ..pylori infection in asymptomatic subjects with gastric parietal cell antibodies, as well as in patients with pernicious anemia, to evaluate a possible role of H. pylori gastric infection in gastric autoimmunity...
  30. ncbi Low frequency of autoantibodies to islet cell, glutamic acid decarboxylase, and second-islet antigen in patients with gestational diabetes mellitus: a follow-up study
    A Lapolla
    Division of Metabolic Diseases, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Ann N Y Acad Sci 958:263-6. 2002
    ..GDM is a complex syndrome, constituted by different types of diabetes mellitus where the autoimmune form is very rare...
  31. doi Anti-heart and anti-intercalated disk autoantibodies: evidence for autoimmunity in idiopathic recurrent acute pericarditis
    A L P Caforio
    Division of Cardiology, Department of Cardiological, Thoracic and Vascular Sciences, Centro V Gallucci, University of Padova Policlinico, Via Giustiniani, 2, Padova 35128, Italy
    Heart 96:779-84. 2010
    ..Control groups included patients with non-inflammatory cardiac disease (NICD) (n=160), ischaemic heart failure (n=141) and normal subjects (n=270)...
  32. ncbi Acute adrenal failure as the heralding symptom of primary antiphospholipid syndrome: report of a case and review of the literature
    Fabio Presotto
    Third Division of Internal Medicine, Department of Medical and Surgical Sciences, University of Padua School of Medicine, I 35128, Padua, Italy
    Eur J Endocrinol 153:507-14. 2005
    ..Our observations emphasize the importance in the assessment of clotting times, and possibly of antiphospholipid antibodies, in all patients with diagnosis of rapidly progressive adrenal failure and concurrent abdominal pain...
  33. ncbi Organ-specific autoantibodies in children with Helicobacter pylori infection
    Graziella Guariso
    Department of Pediatrics, University of Padua, Italy
    Helicobacter 9:622-8. 2004
    ....
  34. ncbi Chronic autoimmune thyroiditis and rheumatic manifestations
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Via Giustiniani 2, Padova 35128, Italy
    Joint Bone Spine 71:275-83. 2004
    ....
  35. ncbi The spectrum of antineuronal autoantibodies in a series of neurological patients
    M Vianello
    Department of Neurological and Psychiatric Sciences, Second Neurological Clinic, University of Padua, Via Facciolati 71, Padua 35127, Italy
    J Neurol Sci 220:29-36. 2004
    ..This may permit identification of subgroups of patients in whom strategies directed at removing and/or suppressing antibody production could be of some benefit...
  36. ncbi Prevalence of coeliac disease in primary biliary cirrhosis and of antimitochondrial antibodies in adult coeliac disease patients in Italy
    A Floreani
    Department of Surgical and Gastroenterological Sciences, University of Padova, Italy
    Dig Liver Dis 34:258-61. 2002
    ..Although an association between primary biliary cirrhosis and coeliac disease has recently been reported in Northern Europe, there are still conflicting data concerning this issue...
  37. doi Autoimmune gastritis: histology phenotype and OLGA staging
    M Rugge
    Department of Medicine, University of Padua, PD, Italy
    Aliment Pharmacol Ther 35:1460-6. 2012
    ..Among Western populations, the declining incidence of Helicobacter pylori infection coincides with a growing clinical impact of autoimmune gastritis...
  38. ncbi Anti-ganglioside antibodies in children with coeliac disease: correlation with gluten-free diet and neurological complications
    C Briani
    Department of Neurosciences, University of Padova, Italy
    Aliment Pharmacol Ther 20:231-5. 2004
    ..No data are so far available on anti-ganglioside antibodies in coeliac disease children or on antibody modifications after gluten-free diet...
  39. ncbi Estimated risk for developing autoimmune Addison's disease in patients with adrenal cortex autoantibodies
    Graziella Coco
    Endocrine Unit, University of Padua Medical School, Italy
    J Clin Endocrinol Metab 91:1637-45. 2006
    ..Patients with adrenal cortex autoantibodies (ACA) without overt autoimmune Addison's disease (AAD) are at risk of adrenal failure...
  40. doi Thymic hyperplasia in patients with Graves' disease
    M Dalla Costa
    Endocrine Unit, Department of Medicine, University of Padova School of Medicine, Via Ospedale Civile 105, 35128, Padova, Italy
    J Endocrinol Invest 37:1175-9. 2014
    ..It is hard to say the real frequency of this latter association because most cases remain asymptomatic and are consequently not thoroughly investigated...
  41. doi Effects of selenium supplementation on the natural course of autoimmune thyroiditis: a short review
    D Petricca
    Department of Medical and Surgical Sciences, University of Padua, Via Ospedale n 105, Padua, Italy
    J Endocrinol Invest 35:419-24. 2012
    ..This review analyzes the effects of Se supplementation in patients with AIT, based on the studies published on this issue to date...
  42. ncbi Fatal toxic epidermal necrolysis in autoimmune polyglandular syndrome type I
    A Porzionato
    Department of Environmental Medicine and Public Health, Forensic Toxicology and Antidoping Unit, Section of Legal Medicine, University of Padua, Padua, Italy
    J Endocrinol Invest 27:475-9. 2004
    ..We stress how such a disease can occur in an autoimmune syndrome, even during corticosteroid treatment...
  43. ncbi 24-hour blood pressure profile in Addison's disease
    F Fallo
    Division of Endocrinology, University of Padova, Italy
    Am J Hypertens 7:1105-9. 1994
    ..Lack of cortisol rhythm or persistent activation of the renin-angiotensin system and sympathetic tone may play a role in this phenomenon...
  44. ncbi Histidine decarboxylase, a pyridoxal phosphate-dependent enzyme, is an autoantigen of gastric enterochromaffin-like cells
    Filip Sköldberg
    Department of Medical Sciences, Uppsala University, University Hospital, 751 85 Uppsala, Sweden
    J Clin Endocrinol Metab 88:1445-52. 2003
    ..To our knowledge, this is the first report of autoantibodies against histidine decarboxylase and absence of gastric enterochromaffin-like cells...
  45. ncbi A sensitive non-isotopic assay for GAD65 autoantibodies
    Helen Brooking
    FIRS Laboratories, RSR Limited, Parc Ty Glas, Llanishen, Cardiff, South Wales, CF14 5DU, UK
    Clin Chim Acta 331:55-9. 2003
    ..A new ELISA for 65 kDa isoform of glutamic acid decarboxylase autoantibodies (GAD(65) Abs), which depends on GAD(65) Ab acting divalently and forming a bridge between immobilized GAD(65) and liquid-phase GAD(65)-biotin, is described...
  46. ncbi Celiac disease and type 1 diabetes
    Francesca Lazzarotto
    Diabetes Care 26:248-9. 2003
  47. ncbi Autoantibodies to human tryptophan hydroxylase and aromatic L-amino acid decarboxylase
    Chiara Dal Pra
    FIRS Laboratories, RSR Ltd, Parc Ty Glas, Llanishen, Cardiff CF14 5DU, UK
    Eur J Endocrinol 150:313-21. 2004
    ..To assess the prevalence of autoantibodies (Abs) to tryptophan hydroxylase (TPH) and aromatic l-amino acid decarboxylase (AADC) in patients with different autoimmune diseases and to analyse their respective epitopes...
  48. ncbi Italian addison network study: update of diagnostic criteria for the etiological classification of primary adrenal insufficiency
    Alberto Falorni
    Department of Internal Medicine, University of Perugia, 06126 Perugia, Italy
    J Clin Endocrinol Metab 89:1598-604. 2004
    ..Lastly, we developed a comprehensive flowchart for the classification of PAI for use in routine clinical practice...
  49. doi Analysis of the GAD65-GAD65 autoantibody interaction
    Graziella Coco
    FIRS Laboratories, RSR Ltd, Parc Ty Glas, Llanishen, Cardiff, UK
    Clin Chim Acta 391:51-9. 2008
    ..GAD(65)Ab are important markers of risk of development of type 1 DM...
  50. doi Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen
    Mohammad Alimohammadi
    University Hospital, Uppsala University, Uppsala, Sweden
    N Engl J Med 358:1018-28. 2008
    ....
  51. ncbi Characterization of antipituitary antibodies targeting pituitary hormone-secreting cells in idiopathic growth hormone deficiency and autoimmune endocrine diseases
    Annamaria De Bellis
    Chair of Endocrinology, Department of Clinical and Experimental Medicine and Surgery F Magrassi and A Lanzara Second University of Naples, 80131, Naples, Italy
    Clin Endocrinol (Oxf) 63:45-9. 2005
    ..In order to investigate whether somatotrophs are the target of antipituitary antibodies (APA) in adult patients with growth hormone deficiency (GHD), we studied the sera of 37 APA positive patients...
  52. ncbi Retrovirus-like long-terminal repeat DQ-LTR13 and genetic susceptibility to type 1 diabetes and autoimmune Addison's disease
    Giovanni Gambelunghe
    Department of Internal Medicine, University of Perugia, Via E dal Pozzo, I 06126 Perugia, Italy
    Diabetes 54:900-5. 2005
    ..We provide conclusive evidence that the genetic association of DQ-LTR13 with type 1 diabetes and AAD is primarily due to a LD with DQB1*0302 and DRB1*0403...
  53. ncbi Onset of type 1 diabetes mellitus during peginterferon alpha-2b plus ribavirin treatment for chronic hepatitis C
    Raffaele Cozzolongo
    Divisione di Gastroenterologia, Ospedale S de Bellis, IRCCS, Castellana Grotte, Bari, Italy
    Eur J Gastroenterol Hepatol 18:689-92. 2006
    ..The patient as a candidate for interferon treatment should therefore be investigated, in addition to thyroid autoimmunity, also for pancreatic autoantibodies before starting therapy...
  54. ncbi MHC2TA single nucleotide polymorphism and genetic risk for autoimmune adrenal insufficiency
    Mehran Ghaderi
    Department of Clinical Pathology and Cytology, Karolinska University Hospital, SE 141 86 Stockholm, Sweden
    J Clin Endocrinol Metab 91:4107-11. 2006
    ..The MHC2TA -168 A-->G single nucleotide polymorphism (rs3087456) has been suggested to confer susceptibility to some autoimmune diseases...
  55. ncbi Peculiar labeling of cultured hippocampal neurons by different sera harboring anti-glutamic acid decarboxylase autoantibodies (GAD-Ab)
    Marika Vianello
    Department of Human Anatomy and Physiology, Section of Physiology, Via Marzolo 3, 35131 Padova, Italy
    Exp Neurol 202:514-8. 2006
    ....
  56. doi Autoantibodies to glutathione S-transferase theta 1 in patients with primary sclerosing cholangitis and other autoimmune diseases
    Brita Ardesjö
    Department of Medical Sciences University Hospital, Research Department 2, Lab 21, Entrance 70, 3rd Floor, Uppsala University, SE 75185 Uppsala, Sweden
    J Autoimmun 30:273-82. 2008
    ..This increased frequency can be explained by an autoimmune phenotype which increases susceptibility to such autoantibodies, or by a high frequency of the GSTT1-null genotype in autoimmune disease...
  57. ncbi Estimation of serum TSH receptor autoantibody concentration and affinity
    Nobuhiro Nakatake
    FIRS Laboratories, RSR Ltd, Llanishen, Cardiff, United Kingdom
    Thyroid 16:1077-84. 2006
    ..Overall, our results indicate that serum TRAb affinities are high and show only limited variations between different sera whereas concentrations of the autoantibodies vary widely...
  58. ncbi Mapping of human autoantibody epitopes on aromatic L-amino acid decarboxylase
    Paola Candeloro
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, Via E dal Pozzo, 06126 Perugia, Italy
    J Clin Endocrinol Metab 92:1096-105. 2007
    ..Little information is currently available on AADC autoantibody epitopes and on the interrelation between autoantibody-mediated inhibition of enzymatic activity and epitope specificity...
  59. ncbi Subclinical hypothyroidism
    Giampaolo Papi
    Curr Opin Endocrinol Diabetes Obes 14:197-208. 2007
    ..The main cause of subclinical hypothyroidism is autoimmune chronic thyroiditis. The present report reviews the most important and recent studies on subclinical hypothyroidism, and discusses the most controversial aspects of this topic...
  60. ncbi Prevalence and clinical significance of circulating cryoglobulins in HIV-positive patients with and without co-infection with hepatitis C virus
    Paolo Fabris
    Department of Infectious Diseases and Tropical Medicine, S Bortolo Hospital, Vicenza, Italy
    J Med Virol 69:339-43. 2003
    ..Typical signs and symptoms of cryoglobulinemia do not correlate with the detection of circulating cryoglobulins in HIV and HCV patients...
  61. doi A human monoclonal autoantibody to the thyrotropin receptor with thyroid-stimulating blocking activity
    Jane Sanders
    FIRS Laboratories, RSR Ltd, Llanishen, Cardiff, United Kingdom
    Thyroid 18:735-46. 2008
    ..To date only one human MAb to the thyrotropin (TSH) receptor (TSHR) with stimulating activity has been available. We now describe the detailed characterization of a blocking type human MAb to the TSHR...
  62. ncbi Analysis of the interaction between human steroid 21-hydroxylase and various monoclonal antibodies using comparative structural modelling
    Ricardo Nunez Miguel
    FIRS Laboratories, RSR Ltd, Parc Ty Glas, Llanishen, Cardiff CF14 5DU, UK
    Eur J Endocrinol 153:949-61. 2005
    ..To study the interaction between human steroid 21-hydroxylase (21-OH) and monoclonal antibodies (MAbs) to 21-OH directed to 3 different epitopes recognised by 21-OH autoantibodies characteristic of autoimmune Addison's disease...