Affiliation: Sesto San Giovanni
- When Rey-Osterrieth's Complex Figure Becomes a Church: Prevalence and Correlates of Graphic Confabulations in DementiaOriana Pelati
Neurology Unit, IRCCS Multimedica, Castellanza
Dement Geriatr Cogn Dis Extra 1:372-80. 2011..On the contrary, GC seems to be the result of a deficit in visual memory replaced by the semantic translation of isolated parts of the ROCF along with a source monitoring deficit...
- Monocyte chemoattractant protein-1 promoter polymorphism and plasma levels in alzheimer's diseaseElisa Porcellini
DIMES, School of Medicine, University of Bologna, Via S, Giacomo 14, Bologna, 40126, Italy
Immun Ageing 10:6. 2013..MCP-1 plasma levels were also measured and correlated to the cognitive impairment (CIND) and AD risk...
- A Population-based study of dementia in the oldest old: the Monzino 80-plus studyUgo Lucca
Laboratory of Geriatric Neuropsychiatry, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
BMC Neurol 11:54. 2011....
- Visuospatial planning and problem solving in Alzheimer's disease patients: a study with the Tower of London TestMassimo Franceschi
Neurology Department, IRCCS Multimedica, Castellanza, Italy
Dement Geriatr Cogn Disord 24:424-8. 2007..The Tower of London (ToL), a task specifically devised to test executive functions of visuospatial planning and problem solving, has frequently been used in neuropsychological experiments, but rarely in the clinical ground...
- Tower of London test: a comparison between conventional statistic approach and modelling based on artificial neural network in differentiating fronto-temporal dementia from Alzheimer's diseaseMassimo Franceschi
Neurology Department, Multimedica Santa Maria, Castellanza, Italy
Behav Neurol 24:149-58. 2011..82. The use of hidden information contained in the different items of ToL and the non linear processing of the data through ANNs allows a high discrimination between FTD and AD in individual patients...
- The frontal assessment battery does not differentiate frontotemporal dementia from Alzheimer's diseaseStefania Castiglioni
Neurology Department, Multimedica Santa Maria, Castellanza, Italy
Dement Geriatr Cogn Disord 22:125-31. 2006..The ability of the FAB to distinguish AD from FTD in mildly demented patients is less clearly assessed...
- CSF metabolites in the differential diagnosis of Alzheimer's disease from frontal variant of frontotemporal dementiaFrancesca de Rino
Department of Neurology, IRCCS Multimedica, Milan, Italy
Neurol Sci 33:973-7. 2012..Our findings suggest that CSF metabolites may be the important tools in the early differential diagnosis between AD and fvFTD, albeit to be correlated with clinical, neuropsychological and bio imaging features...
- Glucose metabolism and serotonin receptors in the frontotemporal lobe degenerationMassimo Franceschi
Neurology Department, Santa Maria Clinic, Castellanza, Varese, Italy
Ann Neurol 57:216-25. 2005..The serotoninergic system dysfunction provides a rationale for therapeutic trials with selective serotonin reuptake inhibitors...
- Prevalence of peripheral nervous system complications after major heart surgeryArmando Gavazzi
Department of Neurology, Multimedica Hospital Castellanza Va, Castellanza, Italy
Neurol Sci 37:205-9. 2016..Careful preoperative assessment and intraoperative management may reduce the risk of long-term PNS complications after cardiac surgery. ..
- Functional disability in early Alzheimer's disease - a validation study of the Italian version of the disability assessment for dementia scaleLuc Pieter De Vreese
Special Dementia Care Unit, Nursing Home Facility IX Gennaio, Modena, Italy
Dement Geriatr Cogn Disord 25:186-94. 2008..To determine the applicability and psychometric properties of the Italian version of the Disability Assessment of Dementia scale (DAD-I) in a community-residing population with early-stage Alzheimer's disease (AD)...
- A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer's diseaseFederico Licastro
Department of Experimental Pathology, School of Medicine, University of Bologna, Via S Giacomo 14, 40126 Bologna, Italy
Neurobiol Aging 26:449-53. 2005..The ACT gene appears to influence the early clinical development of the disease, and the interaction of the ACT and APOE genes affects clinical progression of AD...
- VEGF gene and phenotype relation with Alzheimer's disease and mild cognitive impairmentMartina Chiappelli
Department of Experimental Pathology, School of Medicine, University of Bologna, Bologna, Italy
Rejuvenation Res 9:485-93. 2006..In addition, the authors investigated whether patterns of association also were found for mild cognitive impairment (MCI) and conversion from MCI to AD...
- The hydroxy-methyl-glutaryl CoA reductase promoter polymorphism is associated with Alzheimer's risk and cognitive deteriorationElisa Porcellini
Department of Experimental Pathology, School of Medicine University of Bologna, Via San Giacomo 14, Bologna, Italy
Neurosci Lett 416:66-70. 2007..Present findings reinforce the notion that abnormal regulation of cholesterol metabolism is a key factor in the pathogenesis of the disease...
- Nicastrin gene in familial and sporadic Alzheimer's diseaseAnnamaria Confaloni
Laboratory of Metabolism, Istituto Superiore di Sanita, 00161 Rome, Italy
Neurosci Lett 353:61-5. 2003..We found some differences in the distribution of genotype alterations in the AD population compared to the controls. However, our data together with other evidence did not support the pathological role of missense mutation N417Y...
- Heterogeneity of brain glucose metabolism in mild cognitive impairment and clinical progression to Alzheimer diseaseDavide Anchisi
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele, Milan, Italy
Arch Neurol 62:1728-33. 2005..Subjects with amnesic mild cognitive impairment (aMCI) may include patients at high risk for progression to Alzheimer disease (AD) and a population with different underlying pathologic conditions...
- Presenilin-1 mutation E318G and familial Alzheimer's disease in the Italian populationDiego Albani
Department of Neuroscience, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
Neurobiol Aging 28:1682-8. 2007..05, Mann-Whitney test) in the Abeta(1-42)/Abeta(1-40) ratio in PSEN-1 [E318G] carriers, suggesting a peculiar biochemical effect of this mutation...
- Early-onset Alzheimer disease in an Italian family with presenilin-1 double mutation E318G and G394VSara Batelli
Department of Neuroscience, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, Milan, Italy
Alzheimer Dis Assoc Disord 22:184-7. 2008..We did not find any modification of the A beta(1-42)/A beta(1-40) ratio, suggesting that this double mutation might be involved in early-onset AD etiopathogenesis by affecting a PSEN-1 function other than gamma-secretase activity...
- Age-related quantitative and qualitative changes in decision making abilityValeria Isella
Neuropsychology Unit, Neurology Section, S Gerardo Hospital, Department of Neuroscience, University of Milano Bicocca, Monza, Italy
Behav Neurol 19:59-63. 2008....
- Protein misfolding in Alzheimer's and Parkinson's disease: genetics and molecular mechanismsGianluigi Forloni
Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milan, Italy
Neurobiol Aging 23:957-76. 2002..We also reported data obtained with synthetic peptides and other experimental models, for evaluation of the pathogenic role of mutations in terms of protein misfolding...