Carmela Loguercio

Summary

Affiliation: Second University of Naples
Country: Italy

Publications

  1. ncbi request reprint Oxidative stress in viral and alcoholic hepatitis
    Carmela Loguercio
    Gastroenterology School, 2nd University of Naples, and Inter University Research Center of Alimentary Intake, Nutrition and Digestive Tract CIRANAD, Naples, Italy
    Free Radic Biol Med 34:1-10. 2003
  2. ncbi request reprint Emerging drugs for non-alcoholic fatty liver disease
    Alessandro Federico
    Via Alcide De Gasperi 80, 84018 Scafati SA, Italy
    Expert Opin Emerg Drugs 13:145-58. 2008
  3. ncbi request reprint Cyclic treatment of chronic hepatic encephalopathy with rifaximin. Results of a double-blind clinical study
    C Loguercio
    Gastroenterology School, Second University of Naples, Naples
    Minerva Gastroenterol Dietol 49:53-62. 2003
  4. pmc Herbal products: benefits, limits, and applications in chronic liver disease
    Anna Del Prete
    Department of Clinical and Experimental Medicine, Interuniversity Research Centre on Food, Nutrition and the Gastrointestinal Tract CIRANAD, 2nd University of Naples, 80131 Naples, Italy
    Evid Based Complement Alternat Med 2012:837939. 2012
  5. pmc Coeliac disease and C virus-related chronic hepatitis: a non association
    Antonietta Gerarda Gravina
    Department of Clinical and Experimental Medicine and Surgery F Magrassi e A Lanzara Hepato Gastroenterology Division and C I R A N A D, Second University of Naples, Via Pansini 5, Naples 80131, Italy
    BMC Res Notes 5:533. 2012
  6. ncbi request reprint Focus on irritable bowel syndrome
    A Scalera
    Department of Internal Medicine, University of Naples, Italy
    Eur Rev Med Pharmacol Sci 16:1155-71. 2012
  7. doi request reprint Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial
    Carmela Loguercio
    Department F Magrassi e A Lanzara, Second University of Naples, 80131 Napoli, Italy
    Free Radic Biol Med 52:1658-65. 2012
  8. ncbi request reprint Glutathione supplementation improves oxidative damage in experimental colitis
    C Loguercio
    Gastroenterology Unit, School of Medicine, 2nd University of Naples, Naples, Italy
    Dig Liver Dis 35:635-41. 2003
  9. ncbi request reprint Beneficial effects of a probiotic VSL#3 on parameters of liver dysfunction in chronic liver diseases
    Carmela Loguercio
    Department of Internistica Clinica e Sperimentale F Magrassi e A Lanzara, Inter University Research Center on Foods, Nutrition, and Gastrointestinal Tract CIRANAD, Second University of Naples, Naples, Italy
    J Clin Gastroenterol 39:540-3. 2005
  10. pmc Silybin and the liver: from basic research to clinical practice
    Carmela Loguercio
    Gastroenterology School Interuniversity Research Centre on Foods, Nutrition and Gastrointestinal Tract CIRANAD, 2nd University of Naples, 80131 Naples, Italy
    World J Gastroenterol 17:2288-301. 2011

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Oxidative stress in viral and alcoholic hepatitis
    Carmela Loguercio
    Gastroenterology School, 2nd University of Naples, and Inter University Research Center of Alimentary Intake, Nutrition and Digestive Tract CIRANAD, Naples, Italy
    Free Radic Biol Med 34:1-10. 2003
    ..By enhancing the antioxidant ability of hepatocytes, through transgene vectors, one could counteract oxidative/nitrosative stress and, in this way, contribute to blocking the progression of liver disease...
  2. ncbi request reprint Emerging drugs for non-alcoholic fatty liver disease
    Alessandro Federico
    Via Alcide De Gasperi 80, 84018 Scafati SA, Italy
    Expert Opin Emerg Drugs 13:145-58. 2008
    ..This last form may evolve to cirrhosis and hepatocellular carcinoma...
  3. ncbi request reprint Cyclic treatment of chronic hepatic encephalopathy with rifaximin. Results of a double-blind clinical study
    C Loguercio
    Gastroenterology School, Second University of Naples, Naples
    Minerva Gastroenterol Dietol 49:53-62. 2003
    ..Chronic hepatic encephalopathy (HE) represents a frequent and serious complication of chronic liver disease. Aim of the study is to comparatively evaluate the effect of rifaximin, lactitol and their combination in treating chronic HE...
  4. pmc Herbal products: benefits, limits, and applications in chronic liver disease
    Anna Del Prete
    Department of Clinical and Experimental Medicine, Interuniversity Research Centre on Food, Nutrition and the Gastrointestinal Tract CIRANAD, 2nd University of Naples, 80131 Naples, Italy
    Evid Based Complement Alternat Med 2012:837939. 2012
    ....
  5. pmc Coeliac disease and C virus-related chronic hepatitis: a non association
    Antonietta Gerarda Gravina
    Department of Clinical and Experimental Medicine and Surgery F Magrassi e A Lanzara Hepato Gastroenterology Division and C I R A N A D, Second University of Naples, Via Pansini 5, Naples 80131, Italy
    BMC Res Notes 5:533. 2012
    ....
  6. ncbi request reprint Focus on irritable bowel syndrome
    A Scalera
    Department of Internal Medicine, University of Naples, Italy
    Eur Rev Med Pharmacol Sci 16:1155-71. 2012
    ..Many studies have shown that inflammation and immune dysregulation affect the sensitivity of nerve fibers so it is vital to build on this argument for the development of effective therapies to control the symptoms of this syndrome...
  7. doi request reprint Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial
    Carmela Loguercio
    Department F Magrassi e A Lanzara, Second University of Naples, 80131 Napoli, Italy
    Free Radic Biol Med 52:1658-65. 2012
    ..Treatment with RA but not P for 12 months was associated with improvement in liver enzymes, insulin resistance, and liver histology, without increases in body weight. These findings warrant further investigation...
  8. ncbi request reprint Glutathione supplementation improves oxidative damage in experimental colitis
    C Loguercio
    Gastroenterology Unit, School of Medicine, 2nd University of Naples, Naples, Italy
    Dig Liver Dis 35:635-41. 2003
    ..The pathogenesis of inflammatory bowel disease is due, in part, to enhanced free-radical production and reduced antioxidant potential in mucosa cells...
  9. ncbi request reprint Beneficial effects of a probiotic VSL#3 on parameters of liver dysfunction in chronic liver diseases
    Carmela Loguercio
    Department of Internistica Clinica e Sperimentale F Magrassi e A Lanzara, Inter University Research Center on Foods, Nutrition, and Gastrointestinal Tract CIRANAD, Second University of Naples, Naples, Italy
    J Clin Gastroenterol 39:540-3. 2005
    ..To evaluate whether chronic therapy with probiotics affects plasma levels of cytokines and oxidative/nitrosative stress parameters, as well as liver damage, in patients with various types of chronic liver disease...
  10. pmc Silybin and the liver: from basic research to clinical practice
    Carmela Loguercio
    Gastroenterology School Interuniversity Research Centre on Foods, Nutrition and Gastrointestinal Tract CIRANAD, 2nd University of Naples, 80131 Naples, Italy
    World J Gastroenterol 17:2288-301. 2011
    ..On the basis of literature data, silybin seems a promising drug for chronic liver disease...
  11. doi request reprint Management of chronic liver disease by general practitioners in southern Italy: unmet educational needs
    Carmela Loguercio
    Interuniversity Center for Research on Food, Nutrition and Digestive Tract, Gastroenterology School Second University, Naples, Italy
    Dig Liver Dis 43:736-41. 2011
    ..Despite chronic liver diseases represent an important cause of illness in Italy, data from family practice are poor...
  12. ncbi request reprint Alcoholic beverages and gastric epithelial cell viability: effect on oxidative stress-induced damage
    C Loguercio
    Centro Interuniversitario di Ricerca su Alimenti, Nutrizione e Apparato Digerente Dipartimento Medico Chirurgico di Internistica Clinica e Sperimentale F Magrassi e A Lanzara, Seconda Universita di Napoli, Italia
    J Physiol Pharmacol 60:87-92. 2009
    ..Pre-treatment with red wine, but not with dealcoholate red wine, significantly and time-dependently prevented oxidative stress-induced cell damage...
  13. ncbi request reprint The effect of a silybin-vitamin e-phospholipid complex on nonalcoholic fatty liver disease: a pilot study
    Carmela Loguercio
    Interuniversity Research Center on Foods, Nutrition and Gastrointestinal Tract CIRANAD, Unit of Gastroenterology, Second University of Naples, Naples, Italy
    Dig Dis Sci 52:2387-95. 2007
    ..Our data suggest that silybin conjugated with vitamin E and phospholipids could be used as a complementary approach to the treatment of patients with chronic liver damage...
  14. ncbi request reprint Chronic inflammation and oxidative stress in human carcinogenesis
    Alessandro Federico
    Division of Gastroenterology, F Magrassi and A Lanzara Medical Surgical Department, Second University of Naples, Naples, Italy
    Int J Cancer 121:2381-6. 2007
    ..This review focalizes some of these intricate events by discussing the relationships occurring among oxidative/nitrosative/metabolic stress, inflammation and cancer...
  15. ncbi request reprint Alcoholic Liver Disease and Hepatitis C Chronic Infection
    Alessandro Federico
    Division of Hepatogastroenterology, Department of Clinical and Experimental Medicine, Second University of Naples, Via Pansini 5, 80131 Naples, Italy
    Rev Recent Clin Trials 11:201-7. 2016
    ..Finally we paid attention to the oncogenetic mechanisms inducing hepatocellular carcinoma and variability of response to antiviral therapy that derives from alcohol abuse in a subject affected by C hepatitis. ..
  16. ncbi request reprint Epidemiology and Natural History of Alcoholic Liver Disease
    Mario Masarone
    Internal Medicine and Hepatology Division, Department of Medicine, University of Medicine of Salerno, Salerno, Via Alessandro Manzoni 26b, 80123, Naples, Italy
    Rev Recent Clin Trials 11:167-74. 2016
    ..In this brief review we will report on the global burden of ALD, the principal factors influencing its prevalence among populations and the different presentations of its natural history. ..
  17. pmc Focus on emerging drugs for the treatment of patients with non-alcoholic fatty liver disease
    Alessandro Federico
    Alessandro Federico, Claudio Zulli, Ilario de Sio, Anna Del Prete, Marcello Dallio, Carmela Loguercio, Department of Clinical and Experimental Medicine F Magrassi e A Lanzara, Hepatogastroenterology Division, Interuniversity Research Centre on Food, Nutrition and the Gastrointestinal Tract CIRANAD Second University of Naples, 80131 Naples, Italy
    World J Gastroenterol 20:16841-57. 2014
    ..Urgently, new pharmacological approaches are needed. Here, we will focus on the challenges facing actual therapeutic strategies and the most recent investigated molecules. ..
  18. doi request reprint Intestinal permeability in patients with chronic liver diseases: Its relationship with the aetiology and the entity of liver damage
    Rita Cariello
    Department of Experimental Medicine, Second University of Naples, Italy
    Dig Liver Dis 42:200-4. 2010
    ..Alteration in intestinal permeability may be an important factor in the pathogenesis of both the progression of some chronic liver diseases and the onset of some complications in patients with liver cirrhosis...
  19. doi request reprint The impact of diet on liver fibrosis and on response to interferon therapy in patients with HCV-related chronic hepatitis
    Carmela Loguercio
    Department of Internal Medicine and Hepatogastroenterology, Second University of Naples, Naples, Italy
    Am J Gastroenterol 103:3159-66. 2008
    ..The aim of this study was to evaluate whether dietary composition affects the severity of liver damage and response to therapy in patients with HCV-related chronic hepatitis...
  20. ncbi request reprint Heat shock protein 27 expression in patients with chronic liver damage
    Alessandro Federico
    Centro Interuniversitario per Ricerche su Alimenti, Nutrizione e Apparato Digerente CIRANAD, Cattedra di Gastroenterologia, II Universita di Napoli, Via Pansini 5, Napoli, Italy
    Immunobiology 209:729-35. 2005
    ..The present data are the first showing that, particularly in conditions of enhanced oxidative stress, lymphomonocytes from liver disease patients present an increased expression of HSP27...
  21. doi request reprint Reactivation of hepatitis B virus in cancer patients treated with chemotherapy for solid tumors. Is the prophylaxis really required?
    Alessandro Federico
    Division of Hepatogastroenterology, Second University of Naples, Naples, Italy Electronic address
    Dig Liver Dis 49:197-201. 2017
    ..Reactivation of hepatitis B virus during cancer chemotherapy for non-hematological tumors is not fully clear...
  22. pmc Secondary Extramedullary Plasmacytoma of the Duodenum: An Unusual Endoscopic Presentation
    Antonietta Gerarda Gravina
    Department of Clinical and Experimental Medicine, Gastroenterology Unit, Second University of Naples, Italy These authors contributed equally to this work
    Gastroenterology Res 6:110-111. 2013
    ..The final diagnosis was multiple myeloma IgA lambda, stage II A, with secondary duodenal EMP. To our knowledge this is the first report showing duodenal involvement by EMP with the aspect of multiple non-polypoid lesions...
  23. ncbi request reprint Silybin-Phosphatidylcholine Complex Protects Human Gastric and Liver Cells from Oxidative Stress
    Alessandro Federico
    Department of Clinical and Experimental Medicine, Second University of Naples, Naples, Italy
    In Vivo 29:569-75. 2015
    ....
  24. ncbi request reprint Non alcoholic fatty liver: epidemiology and natural history
    Mario Masarone
    Via Alessandro Manzoni 26b, 80123, Naples, Italy
    Rev Recent Clin Trials 9:126-33. 2014
    ..In this review we will report on the global and regional prevalence of NAFLD, the principal risk factors and the natural history of its different presentations. ..
  25. doi request reprint Targeting gut-liver axis for the treatment of nonalcoholic steatohepatitis: translational and clinical evidence
    Alessandro Federico
    Division of Hepatogastroenterology, Department of Clinical and Experimental Medicine, Second University of Naples, Naples, Italy
    Transl Res 167:116-24. 2016
    ..In this review, we summarized the evidence regarding the role of gut-liver axis in the pathogenesis of NASH and discussed the potential therapeutic role of gut microbiota modulation in the clinical setting...
  26. ncbi request reprint Telaprevir may induce adverse cutaneous reactions by a T cell immune-mediated mechanism
    Alessandro Federico
    Department of Clinical and Experimental Medicine, Second University of Naples, Naples, Italy
    Ann Hepatol 14:420-4. 2015
    ..05). In conclusion, adverse cutaneous reactions of our patient were caused by a telaprevir-induced T-cell dependent immune mechanism. ..
  27. pmc Eradication of Helicobacter pylori infection: which regimen first?
    Alessandro Federico
    Alessandro Federico, Antonietta Gerarda Gravina, Agnese Miranda, Carmela Loguercio, Marco Romano, Department of Clinical and Experimental Medicine, Gastroenterology Unit, Second University of Naples, 80131 Naples, Italy
    World J Gastroenterol 20:665-72. 2014
    ..A first-line eradication regimen should be based on what works best in a defined geographical area and must take into account the prevalence of antimicrobial resistance in that region. ..
  28. ncbi request reprint Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: a double-blind, randomized trial
    Giulio Marchesini
    Department of Internal Medicine, Alma Mater Studiorum University of Bologna, Bologna, Italy
    Gastroenterology 124:1792-801. 2003
    ..The role of oral supplementation with branched-chain amino acids (BCAA) in advanced cirrhosis is far from settled. A nutritional approach might prevent progressive liver failure and improve nutritional parameters and quality of life...
  29. ncbi request reprint Gut-liver axis: a new point of attack to treat chronic liver damage?
    Carmela Loguercio
    Am J Gastroenterol 97:2144-6. 2002