Chiara Cerami

Summary

Affiliation: San Raffaele Scientific Institute
Country: Italy

Publications

  1. ncbi Imaging neuroinflammation in ischemic stroke and in the atherosclerotic vascular disease
    Chiara Cerami
    Department of Nuclear Medicine and Division of Neuroscience, Vita Salute University and San Raffaele Scientific Institute, Via Olgettina 60 20134, Milan, Italy
    Curr Vasc Pharmacol 13:218-22. 2015
  2. doi Motor neuron dysfunctions in the frontotemporal lobar degeneration spectrum: a clinical and neurophysiological study
    C Cerami
    Vita Salute San Raffaele University, Milan, Italy Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy Neurorehabilitation Unit, Department of Clinical Neurosciences, San Raffaele Hospital, Milan, Italy Electronic address
    J Neurol Sci 351:72-7. 2015
  3. doi Novel missense progranulin gene mutation associated with the semantic variant of primary progressive aphasia
    Chiara Cerami
    Neurorehabilitation Unit, Department of Clinical Neurosciences, San Raffaele Scientific Institute and Universita Vita Salute San Raffaele, Via Olgettina 60, Milan, Italy
    J Alzheimers Dis 36:415-20. 2013
  4. doi From genotype to phenotype: two cases of genetic frontotemporal lobar degeneration with premorbid bipolar disorder
    Chiara Cerami
    Neurorehabilitation Unit, Department of Clinical Neurosciences, Vita Salute University and San Raffaele Scientific Institute, Milan, Italy
    J Alzheimers Dis 27:791-7. 2011
  5. doi The behavioral variant of frontotemporal dementia: linking neuropathology to social cognition
    Chiara Cerami
    Neurorehabilitation Unit, Department of Clinical Neurosciences, San Raffaele Scientific Institute and Universita Vita Salute San Raffaele, Via Olgettina 60, 20132, Milan, Italy
    Neurol Sci 34:1267-74. 2013
  6. doi Novel evidence of phenotypical variability in the hexanucleotide repeat expansion in chromosome 9
    Chiara Cerami
    Neurorehabilitation Unit, Department of Clinical Neurosciences, San Raffaele Scientific Institute, Via Olgettina 60, Milan, Italy
    J Alzheimers Dis 35:455-62. 2013
  7. doi Differential Impairment of Cognitive and Affective Mentalizing Abilities in Neurodegenerative Dementias: Evidence from Behavioral Variant of Frontotemporal Dementia, Alzheimer's Disease, and Mild Cognitive Impairment
    Alessandra Dodich
    Universita Vita Salute San Raffaele, Milan, Italy
    J Alzheimers Dis 50:1011-22. 2016
  8. doi Cross-validation of biomarkers for the early differential diagnosis and prognosis of dementia in a clinical setting
    Daniela Perani
    Vita Salute San Raffaele University, Via Olgettina, 58, 20132, Milan, Italy
    Eur J Nucl Med Mol Imaging 43:499-508. 2016
  9. doi Different FDG-PET metabolic patterns at single-subject level in the behavioral variant of fronto-temporal dementia
    Chiara Cerami
    Vita Salute San Raffaele University, Milan, Italy Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy Clinical Neuroscience Department, San Raffaele Turro Hospital, Milan, Italy
    Cortex 83:101-12. 2016
  10. doi A novel task assessing intention and emotion attribution: Italian standardization and normative data of the Story-based Empathy Task
    Alessandra Dodich
    Universita Vita Salute San Raffaele, Via Olgettina 58, 20134, Milan, Italy
    Neurol Sci 36:1907-12. 2015

Collaborators

Detail Information

Publications26

  1. ncbi Imaging neuroinflammation in ischemic stroke and in the atherosclerotic vascular disease
    Chiara Cerami
    Department of Nuclear Medicine and Division of Neuroscience, Vita Salute University and San Raffaele Scientific Institute, Via Olgettina 60 20134, Milan, Italy
    Curr Vasc Pharmacol 13:218-22. 2015
    ....
  2. doi Motor neuron dysfunctions in the frontotemporal lobar degeneration spectrum: a clinical and neurophysiological study
    C Cerami
    Vita Salute San Raffaele University, Milan, Italy Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy Neurorehabilitation Unit, Department of Clinical Neurosciences, San Raffaele Hospital, Milan, Italy Electronic address
    J Neurol Sci 351:72-7. 2015
    ..The aim of this study is to evaluate MNDys and ALS in a sample of consecutively enrolled sporadic FTLD patients...
  3. doi Novel missense progranulin gene mutation associated with the semantic variant of primary progressive aphasia
    Chiara Cerami
    Neurorehabilitation Unit, Department of Clinical Neurosciences, San Raffaele Scientific Institute and Universita Vita Salute San Raffaele, Via Olgettina 60, Milan, Italy
    J Alzheimers Dis 36:415-20. 2013
    ..This case confirms that GRN represents one of the most frequent FTLD genetic causes, suggesting that a screening is indicated in the case of svPPA presentation. ..
  4. doi From genotype to phenotype: two cases of genetic frontotemporal lobar degeneration with premorbid bipolar disorder
    Chiara Cerami
    Neurorehabilitation Unit, Department of Clinical Neurosciences, Vita Salute University and San Raffaele Scientific Institute, Milan, Italy
    J Alzheimers Dis 27:791-7. 2011
    ..11019_11022delCACT mutation in Northern Italy. On this basis, we recommend to consider the presence of this mutation as a possible cause of the disease, particularly in patients with premorbid psychiatric symptoms...
  5. doi The behavioral variant of frontotemporal dementia: linking neuropathology to social cognition
    Chiara Cerami
    Neurorehabilitation Unit, Department of Clinical Neurosciences, San Raffaele Scientific Institute and Universita Vita Salute San Raffaele, Via Olgettina 60, 20132, Milan, Italy
    Neurol Sci 34:1267-74. 2013
    ..We also briefly summarize the available genetic information about the frontotemporal lobar degeneration spectrum...
  6. doi Novel evidence of phenotypical variability in the hexanucleotide repeat expansion in chromosome 9
    Chiara Cerami
    Neurorehabilitation Unit, Department of Clinical Neurosciences, San Raffaele Scientific Institute, Via Olgettina 60, Milan, Italy
    J Alzheimers Dis 35:455-62. 2013
    ..The present findings confirm the importance of screening for the hexanucleotide repeat expansion in chromosome 9 in the case not only of familial, but also of sporadic FTD, and in the presence of atypical cognitive disorders...
  7. doi Differential Impairment of Cognitive and Affective Mentalizing Abilities in Neurodegenerative Dementias: Evidence from Behavioral Variant of Frontotemporal Dementia, Alzheimer's Disease, and Mild Cognitive Impairment
    Alessandra Dodich
    Universita Vita Salute San Raffaele, Milan, Italy
    J Alzheimers Dis 50:1011-22. 2016
    ..The overall deficit in the task in AD appears to be more general and related to the severity of dementia. This latter finding is further supported by the normal performance of the prodromal AD group. ..
  8. doi Cross-validation of biomarkers for the early differential diagnosis and prognosis of dementia in a clinical setting
    Daniela Perani
    Vita Salute San Raffaele University, Via Olgettina, 58, 20132, Milan, Italy
    Eur J Nucl Med Mol Imaging 43:499-508. 2016
    ....
  9. doi Different FDG-PET metabolic patterns at single-subject level in the behavioral variant of fronto-temporal dementia
    Chiara Cerami
    Vita Salute San Raffaele University, Milan, Italy Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy Clinical Neuroscience Department, San Raffaele Turro Hospital, Milan, Italy
    Cortex 83:101-12. 2016
    ..Different variants of this pattern of brain involvement may, however, be found in individual cases, supporting the presence of heterogeneous phenotypes...
  10. doi A novel task assessing intention and emotion attribution: Italian standardization and normative data of the Story-based Empathy Task
    Alessandra Dodich
    Universita Vita Salute San Raffaele, Via Olgettina 58, 20134, Milan, Italy
    Neurol Sci 36:1907-12. 2015
    ..This new task could be a useful tool to investigate both affective and cognitive aspects of ToM in the course of disorders of socio-emotional behaviour, such as the fronto-temporal dementia spectrum...
  11. pmc The Role of Single-Subject Brain Metabolic Patterns in the Early Differential Diagnosis of Primary Progressive Aphasias and in Prediction of Progression to Dementia
    Chiara Cerami
    Vita Salute San Raffaele University, Milan, Italy
    J Alzheimers Dis 55:183-197. 2017
    ..In this study, we investigated in PPA the FDG-PET brain metabolic patterns at the single-subject level, in order to assess the case-to-case variability and its relationship with clinical-neuropsychological findings...
  12. doi Neuropsychological and FDG-PET profiles in VGKC autoimmune limbic encephalitis
    Alessandra Dodich
    Universita Vita Salute San Raffaele, Milan, Italy Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy Electronic address
    Brain Cogn 108:81-7. 2016
    ..In this study, we assessed at the individual level FDG-PET brain metabolic dysfunctions and neuropsychological profiles in three autoimmune LE cases seropositive for neuronal VGKC-complex autoantibodies...
  13. pmc Right Limbic FDG-PET Hypometabolism Correlates with Emotion Recognition and Attribution in Probable Behavioral Variant of Frontotemporal Dementia Patients
    Chiara Cerami
    Vita Salute San Raffaele University, Milan, Italy Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy Clinical Neuroscience Department, San Raffaele Hospital, Milan, Italy
    PLoS ONE 10:e0141672. 2015
    ..The derangement of a right limbic network is associated with altered socio-emotional processing in bvFTD patients, but different hypometabolic FDG-PET patterns and heterogeneous performances on social tasks at an individual level exist. ..
  14. pmc Affective mentalizing and brain activity at rest in the behavioral variant of frontotemporal dementia
    Silvia P Caminiti
    Universita Vita Salute San Raffaele, Milan, Italy In Vivo Human Molecular and Structural Neuroimaging, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy
    Neuroimage Clin 9:484-97. 2015
    ..Distinctive patterns of abnormal brain functioning at rest have been reported in bvFTD, but their relationship with defective attribution of affective states has not been investigated...
  15. doi Neural correlates of empathic impairment in the behavioral variant of frontotemporal dementia
    Chiara Cerami
    Universita Vita Salute San Raffaele, Milan, Italy Department of Clinical Neurosciences, San Raffaele Scientific Institute, Milan, Italy Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy
    Alzheimers Dement 10:827-34. 2014
    ..In this study, we directly compared two empathy components (intention attribution [IA] and emotion attribution [EA]), correlating them with possible specific patterns of gray-matter density reduction within the mentalizing network...
  16. doi Brain changes within the visuo-spatial attentional network in posterior cortical atrophy
    Chiara Cerami
    Universita Vita Salute San Raffaele, Milan, Italy Clinical Neuroscience Department, San Raffaele Hospital, Milan, Italy
    J Alzheimers Dis 43:385-95. 2015
    ....
  17. doi Progranulin gene (GRN) promoter methylation is increased in patients with sporadic frontotemporal lobar degeneration
    Daniela Galimberti
    Department of Pathophysiology and Transplantation, University of Milan, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy
    Neurol Sci 34:899-903. 2013
    ..05). GRN promoter methylation was not correlated with age. In conclusion, the degree of methylation of the GRN promoter is increased in patients with FTLD as compared with controls, likely leading to a decreased expression of GRN...
  18. doi Emotion recognition from facial expressions: a normative study of the Ekman 60-Faces Test in the Italian population
    Alessandra Dodich
    Universita Vita Salute San Raffaele, Milan, Italy
    Neurol Sci 35:1015-21. 2014
    ..We provided EK-60F Test normative data for the Italian population allowing the investigation of global emotion recognition ability as well as selective impairment of basic emotions recognition, both for clinical and research purposes...
  19. pmc Brain metabolic maps in Mild Cognitive Impairment predict heterogeneity of progression to dementia
    Chiara Cerami
    Universita Vita Salute San Raffaele, Milan, Italy Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy Clinical Neuroscience Department, Neurorehabilitation Unit, San Raffaele Hospital, Milan, Italy
    Neuroimage Clin 7:187-94. 2015
    ..These data support the potential usefulness of this SPM [(18)F]FDG PET analysis in the early dementia diagnosis and for improving subject selection in clinical trials based on MCI definition. ..
  20. pmc The cognitive and behavioural profile of amyotrophic lateral sclerosis: application of the consensus criteria
    Monica Consonni
    Department of Clinical Neurosciences and Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy Vita Salute University, Via Olgettina, Milan, Italy
    Behav Neurol 27:143-53. 2013
    ..The study also intends to assess the impact of physical disability on cognitive and behavioural abnormalities...
  21. doi Genetics and expression analysis of the specificity protein 4 gene (SP4) in patients with Alzheimer's disease and frontotemporal lobar degeneration
    Chiara Villa
    Department of Neurological Sciences, Dino Ferrari Center, University of Milan, Fondazione Cà Granda, IRCCS Ospedale Policlinico, Milan, Italy
    J Alzheimers Dis 31:537-42. 2012
    ..However, Sp4 mRNA levels are upregulated in patients, possibly resulting in an aberrant expression of downstream target genes involved in the pathogenesis of both diseases...
  22. pmc Validation of an optimized SPM procedure for FDG-PET in dementia diagnosis in a clinical setting
    Daniela Perani
    Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy Vita Salute San Raffaele University, Milan, Italy Nuclear Medicine Unit, San Raffaele Hospital, Milan, Italy Istituto di Bioimmagini e Fisiologia Molecolare, CNR, Segrate, Italy
    Neuroimage Clin 6:445-54. 2014
    ..In the MCI group, SPM Maps showed the highest predictive prognostic value (mean LOC = 2.46), by identifying either normal brain metabolism (exclusionary role) or hypometabolic patterns typical of different neurodegenerative conditions...
  23. doi Microstructural white matter correlates of emotion recognition impairment in Amyotrophic Lateral Sclerosis
    Chiara Crespi
    Universita Vita Salute San Raffaele, Milan, Italy San Raffaele Scientific Institute, Milan, Italy Electronic address
    Cortex 53:1-8. 2014
    ..These changes may represent a frontotemporal-limbic microstructural marker of socio-emotional impairment in ALS. ..
  24. doi Frontotemporal lobar degeneration: current knowledge and future challenges
    Chiara Cerami
    Neurorehabilitation Unit, Department of Clinical Neurosciences, San Raffaele Scientific Institute, Vita Salute University, Milan, Italy
    J Neurol 259:2278-86. 2012
    ..In addition, other genes are linked to rare cases of familiar FTLD. Lastly, a number of genetic risk factors for sporadic forms have also been identified...
  25. doi Serotonin transporter and saitohin genes in risk of Alzheimer's disease and frontotemporal lobar dementia: preliminary findings
    Cristina Lorenzi
    Clinical Neurosciences Department, San Raffaele Turro Hospital, Vita Salute San Raffaele University, Via Stamira d Ancona 20, Milan, Italy
    Neurol Sci 31:741-9. 2010
    ..Our study confirms the role of 5-HTTLPR as a potential susceptibility factor for sporadic dementia in the Italian population, and suggests a possible interaction between 5-HTTLPR and Q7R polymorphisms in neurodegenerative diseases...
  26. doi Epidural premotor cortical stimulation in primary focal dystonia: clinical and 18F-fluoro deoxyglucose positron emission tomography open study
    Stefania Lalli
    Department of Neurology I, IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
    Mov Disord 27:533-8. 2012
    ..Patients with prevalently fixed cervical dystonia had a reduced benefit. Presurgical neuroimaging revealed a significant bilateral metabolic increase in the sensorimotor areas, which was reduced after surgery...