Mario Rango

Summary

Country: Italy

Publications

  1. doi request reprint Parkinson's disease: in vivo brain metabolomics by MRS
    Mario Rango
    Department of Neurological Sciences and Excellence Center for advanced MR studies, IRCCS Ca Granda Ospedale Maggiore Policlinico Foundation, University of Milan, Milano, Italy Electronic address
    Int Rev Neurobiol 122:81-94. 2015
  2. doi request reprint PINK1 parkinsonism and Parkinson disease: distinguishable brain mitochondrial function and metabolomics
    M Rango
    Magnetic Resonance Spectroscopy Center, Fondazione Cà Granda, Policlinico, University of Milan, Milan, Italy
    Mitochondrion 13:59-61. 2013
  3. doi request reprint Central hyperthermia, brain hyperthermia and low hypothalamus temperature
    Mario Rango
    The Department of Neurological Sciences and The Center for Magnetic Resonance Spectroscopy, Foundation Cà Granda, Ospedale Policlinico, University of Milan, Milan, Italy
    Clin Auton Res 22:299-301. 2012
  4. doi request reprint Brain temperature: what do we know?
    Mario Rango
    Department of Neurological Sciences, Maggiore Policlinico Hospital Ca Granda Foundation, University of Milan, Milan, Italy
    Neuroreport 23:483-7. 2012
  5. doi request reprint Increased brain temperature in Parkinson's disease
    Mario Rango
    Department of Neurological Sciences, Parkinson s Disease Center, IRCCS Ca Granda Ospedale Maggiore Policlinico Foundation, University of Milan, Via F Sforza 35, Milan, Italy
    Neuroreport 23:129-33. 2012
  6. ncbi request reprint Parkinson's disease and brain mitochondrial dysfunction: a functional phosphorus magnetic resonance spectroscopy study
    Mario Rango
    Department of Neurological Sciences, Parkinson s Disease Center, Maggiore Policlinico Hospital, IRCCS, University of Milan, Milan, Italy
    J Cereb Blood Flow Metab 26:283-90. 2006
  7. ncbi request reprint Parkinson's disease, chronic hydrocarbon exposure and striatal neuronal damage: a 1-H MRS study
    M Rango
    Dipartimento di Scienze Neurologiche Centro per il Morbo di Parkinson, Ospedale Maggiore Policlinico, IRCCS, Universita degli Studi di Milano, Milano, Italy
    Neurotoxicology 27:164-8. 2006
  8. ncbi request reprint Magnetic resonance spectroscopy in Parkinson's disease and parkinsonian syndromes
    Mario Rango
    Department of Neurology, IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation, Milan, Italy
    Funct Neurol 22:75-9. 2007
  9. doi request reprint Lactate detection in the brain of growth-restricted fetuses with magnetic resonance spectroscopy
    Irene Cetin
    Center for Fetal Research Giorgio Pardi, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
    Am J Obstet Gynecol 205:350.e1-7. 2011
  10. pmc The brain is hypothermic in patients with mitochondrial diseases
    Mario Rango
    1 Department of Neurological Sciences, IRCCS Ca Granda Ospedale Maggiore Policlinico Foundation, University of Milan, Milan, Italy 2 Magnetic Resonance Spectroscopy Center, IRCCS Ca Granda Ospedale Maggiore Policlinico Foundation, University of Milan, Milan, Italy
    J Cereb Blood Flow Metab 34:915-20. 2014

Collaborators

Detail Information

Publications16

  1. doi request reprint Parkinson's disease: in vivo brain metabolomics by MRS
    Mario Rango
    Department of Neurological Sciences and Excellence Center for advanced MR studies, IRCCS Ca Granda Ospedale Maggiore Policlinico Foundation, University of Milan, Milano, Italy Electronic address
    Int Rev Neurobiol 122:81-94. 2015
    ..This chapter will review brain metabolomics in the human brain as studied noninvasively by magnetic resonance spectroscopy. Although preliminary, the results shed some light on the pathophysiology of Parkinson's disease. ..
  2. doi request reprint PINK1 parkinsonism and Parkinson disease: distinguishable brain mitochondrial function and metabolomics
    M Rango
    Magnetic Resonance Spectroscopy Center, Fondazione Cà Granda, Policlinico, University of Milan, Milan, Italy
    Mitochondrion 13:59-61. 2013
    ..Apart from a few typical EOP findings, the clinical features and SPECT mostly overlapped with typical idiopathic PD. Brain metabolomics, as examined by magnetic resonance spectroscopy and PET, were clearly distinguishable...
  3. doi request reprint Central hyperthermia, brain hyperthermia and low hypothalamus temperature
    Mario Rango
    The Department of Neurological Sciences and The Center for Magnetic Resonance Spectroscopy, Foundation Cà Granda, Ospedale Policlinico, University of Milan, Milan, Italy
    Clin Auton Res 22:299-301. 2012
    ..INTRODUCTION, PATIENTS AND METHODS: We measured brain temperature in a case of central hyperthermia...
  4. doi request reprint Brain temperature: what do we know?
    Mario Rango
    Department of Neurological Sciences, Maggiore Policlinico Hospital Ca Granda Foundation, University of Milan, Milan, Italy
    Neuroreport 23:483-7. 2012
    ..A full understanding of brain temperature control is mandatory to optimize attempts at brain cooling during clinical conditions such as stroke and head injury...
  5. doi request reprint Increased brain temperature in Parkinson's disease
    Mario Rango
    Department of Neurological Sciences, Parkinson s Disease Center, IRCCS Ca Granda Ospedale Maggiore Policlinico Foundation, University of Milan, Via F Sforza 35, Milan, Italy
    Neuroreport 23:129-33. 2012
    ..The increase in brain temperature is best explained by an energy loss along the oxidative phosphorylation/respiratory chain...
  6. ncbi request reprint Parkinson's disease and brain mitochondrial dysfunction: a functional phosphorus magnetic resonance spectroscopy study
    Mario Rango
    Department of Neurological Sciences, Parkinson s Disease Center, Maggiore Policlinico Hospital, IRCCS, University of Milan, Milan, Italy
    J Cereb Blood Flow Metab 26:283-90. 2006
    ..The combined use of MRS and brain activation is fundamental for the study of brain energetics in patients with PD and may prove an important tool for diagnostic purposes and, possibly, to monitor therapeutic interventions...
  7. ncbi request reprint Parkinson's disease, chronic hydrocarbon exposure and striatal neuronal damage: a 1-H MRS study
    M Rango
    Dipartimento di Scienze Neurologiche Centro per il Morbo di Parkinson, Ospedale Maggiore Policlinico, IRCCS, Universita degli Studi di Milano, Milano, Italy
    Neurotoxicology 27:164-8. 2006
    ..Clinical expression is more severe in PD patients with previous high degree solvent exposure because of the associated post-synaptic damage of the nigro-striatal pathway...
  8. ncbi request reprint Magnetic resonance spectroscopy in Parkinson's disease and parkinsonian syndromes
    Mario Rango
    Department of Neurology, IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation, Milan, Italy
    Funct Neurol 22:75-9. 2007
    ..MRS is useful for diagnostic purposes, helping to differentiate Parkinson's disease from other parkinsonian syndromes. Even more usefully, MRS can be used for non invasive in vivo human research...
  9. doi request reprint Lactate detection in the brain of growth-restricted fetuses with magnetic resonance spectroscopy
    Irene Cetin
    Center for Fetal Research Giorgio Pardi, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
    Am J Obstet Gynecol 205:350.e1-7. 2011
    ....
  10. pmc The brain is hypothermic in patients with mitochondrial diseases
    Mario Rango
    1 Department of Neurological Sciences, IRCCS Ca Granda Ospedale Maggiore Policlinico Foundation, University of Milan, Milan, Italy 2 Magnetic Resonance Spectroscopy Center, IRCCS Ca Granda Ospedale Maggiore Policlinico Foundation, University of Milan, Milan, Italy
    J Cereb Blood Flow Metab 34:915-20. 2014
    ..In patients with mitochondrial diseases, the brain is hypothermic because of malfunctioning oxidative phosphorylation. Neuronal activity is reduced at rest, during physiologic brain stimulation, and after stimulation. ..
  11. doi request reprint Human fetal brain chemistry as detected by proton magnetic resonance spectroscopy
    Erika Brighina
    Foundation Instituto di Ricerca e Cura a Carattere Scientifico Policlinico, Mangiagalli and Regina Elena, University of Milan, Milan, Italy
    Pediatr Neurol 40:327-42. 2009
    ....
  12. doi request reprint Usefulness of Multi-Parametric MRI for the Investigation of Posterior Cortical Atrophy
    Andrea Arighi
    Neurology Unit, Department of Pathophysiology and Transplantation, University of Milan, Foundation IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20121, Milan, Italy
    PLoS ONE 10:e0140639. 2015
    ....
  13. doi request reprint Post-Activation Brain Warming: A 1-H MRS Thermometry Study
    Mario Rango
    Department of Neurological Sciences, IRCCS Ca Granda Ospedale Maggiore Policlinico Foundation, University of Milan, Milan, Italy Magnetic Resonance Spectroscopy Center, IRCCS Ca Granda Ospedale Maggiore Policlinico Foundation, University of Milan, Milan, Italy
    PLoS ONE 10:e0127314. 2015
    ..Temperature plays a fundamental role for the proper functioning of the brain. However, there are only fragmentary data on brain temperature (T(br)) and its regulation under different physiological conditions...
  14. doi request reprint A 66-year-old patient with vanishing white matter disease due to the p.Ala87Val EIF2B3 mutation
    Laura Ghezzi
    Department of Neurological Sciences, University of Milan, Fondazione Cà Granda, IRCCS Ospedale Policlinico, Milan, Italy
    Neurology 79:2077-8. 2012
    ..Mutations in any of the genes encoding the 5 subunits of the Eukaryotic Initiation Factor 2B gene (EIF2B1, 2, 3, 4, and 5) can independently cause VWM.(1)...
  15. ncbi request reprint Parkin polymorphisms and environmental exposure: decrease in age at onset of Parkinson's disease
    Isabella Ghione
    Centro per il Morbo di Parkinson, Centro Dino Ferrari, Department of Neurological Sciences, University of Milan, Fondazione I R C C S, Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Neurotoxicology 28:698-701. 2007
    ..Individuals with environmental/occupational exposure should be screened for the presence of parkin SNPs...
  16. doi request reprint Spontaneous blinking in healthy persons: an optoelectronic study of eyelid motion
    Chiarella Sforza
    Functional Anatomy Research Center FARC, Universita degli Studi, Milano, Italy
    Ophthalmic Physiol Opt 28:345-53. 2008
    ..To develop a method for the non-invasive detection and quantification of eyelid movements during spontaneous blinking...