Domenico Palli

Summary

Country: Italy

Publications

  1. pmc Reproductive factors and risk of hormone receptor positive and negative breast cancer: a cohort study
    Rebecca Ritte
    Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Heidelberg, Germany
    BMC Cancer 13:584. 2013
  2. doi request reprint Environmental ozone exposure and oxidative DNA damage in adult residents of Florence, Italy
    Domenico Palli
    Molecular and Nutritional Epidemiology Unit, Cancer Prevention and Research Institute ISPO, Via Cosimo il Vecchio 2, 50139 Florence, Italy
    Environ Pollut 157:1521-5. 2009
  3. pmc Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study
    Rebecca Ritte
    Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Im Neuenheimer Feld TP4, Heidelberg, 69120, Germany
    Breast Cancer Res 14:R76. 2012
  4. pmc Meat consumption and mortality--results from the European Prospective Investigation into Cancer and Nutrition
    Sabine Rohrmann
    Division of Cancer Epidemiology and Prevention, Institute of Social and Preventive Medicine, University of Zurich, 8001 Zurich, Switzerland
    BMC Med 11:63. 2013
  5. doi request reprint DNA adducts and PM(10) exposure in traffic-exposed workers and urban residents from the EPIC-Florence City study
    Domenico Palli
    Molecular and Nutritional Epidemiology Unit, CSPO Scientific Institute of Tuscany, Florence, Italy
    Sci Total Environ 403:105-12. 2008
  6. doi request reprint Bulky DNA adducts and breast cancer risk in the prospective EPIC-Italy study
    Calogero Saieva
    Molecular and Nutritional Epidemiology Unit, ISPO Cancer Research and Prevention Institute, Ponte Nuovo, Via delle Oblate 2, 50139, Florence, Italy
    Breast Cancer Res Treat 129:477-84. 2011
  7. doi request reprint Physical activity and mammographic breast density in a Mediterranean population: the EPIC Florence longitudinal study
    Giovanna Masala
    Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute, Florence, Italy
    Int J Cancer 124:1654-61. 2009
  8. doi request reprint Fruit and vegetables consumption and breast cancer risk: the EPIC Italy study
    Giovanna Masala
    Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute ISPO, Ponte Nuovo Palazzina 28 A, Via delle Oblate 4, 50141 Florence, Italy
    Breast Cancer Res Treat 132:1127-36. 2012
  9. doi request reprint Anthropometric and dietary determinants of blood pressure in over 7000 Mediterranean women: the European Prospective Investigation into Cancer and Nutrition-Florence cohort
    Giovanna Masala
    Molecular and Nutritional Epidemiology Unit, ISPO, Florence, Italy
    J Hypertens 26:2112-20. 2008
  10. pmc Association between the BRCA2 N372H variant and male breast cancer risk: a population-based case-control study in Tuscany, Central Italy
    Domenico Palli
    Molecular and Nutritional Epidemiology Unit, CSPO, Scientific Institute of Tuscany, 50139 Florence, Italy
    BMC Cancer 7:170. 2007

Detail Information

Publications31

  1. pmc Reproductive factors and risk of hormone receptor positive and negative breast cancer: a cohort study
    Rebecca Ritte
    Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Heidelberg, Germany
    BMC Cancer 13:584. 2013
    ..The association of reproductive factors with hormone receptor (HR)-negative breast tumors remains uncertain...
  2. doi request reprint Environmental ozone exposure and oxidative DNA damage in adult residents of Florence, Italy
    Domenico Palli
    Molecular and Nutritional Epidemiology Unit, Cancer Prevention and Research Institute ISPO, Via Cosimo il Vecchio 2, 50139 Florence, Italy
    Environ Pollut 157:1521-5. 2009
    ..Our results suggest that ozone concentrations at ground levels modulate oxidative DNA damage in circulating lymphocytes of residents of polluted areas...
  3. pmc Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study
    Rebecca Ritte
    Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Im Neuenheimer Feld TP4, Heidelberg, 69120, Germany
    Breast Cancer Res 14:R76. 2012
    ....
  4. pmc Meat consumption and mortality--results from the European Prospective Investigation into Cancer and Nutrition
    Sabine Rohrmann
    Division of Cancer Epidemiology and Prevention, Institute of Social and Preventive Medicine, University of Zurich, 8001 Zurich, Switzerland
    BMC Med 11:63. 2013
    ..The aim of this study was to examine the association of red meat, processed meat, and poultry consumption with the risk of early death in the European Prospective Investigation into Cancer and Nutrition (EPIC)...
  5. doi request reprint DNA adducts and PM(10) exposure in traffic-exposed workers and urban residents from the EPIC-Florence City study
    Domenico Palli
    Molecular and Nutritional Epidemiology Unit, CSPO Scientific Institute of Tuscany, Florence, Italy
    Sci Total Environ 403:105-12. 2008
    ..Since DNA adduct levels have been found predictive of lung cancer risk, our findings provide clues relevant to the reduction of genotoxic damage and possibly cancer risk among traffic-exposed urban workers...
  6. doi request reprint Bulky DNA adducts and breast cancer risk in the prospective EPIC-Italy study
    Calogero Saieva
    Molecular and Nutritional Epidemiology Unit, ISPO Cancer Research and Prevention Institute, Ponte Nuovo, Via delle Oblate 2, 50139, Florence, Italy
    Breast Cancer Res Treat 129:477-84. 2011
    ..Larger studies by using different methods and/or biomarkers are needed to better evaluate the role of specific environmental carcinogens in breast carcinogenesis...
  7. doi request reprint Physical activity and mammographic breast density in a Mediterranean population: the EPIC Florence longitudinal study
    Giovanna Masala
    Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute, Florence, Italy
    Int J Cancer 124:1654-61. 2009
    ..34; 95% CI 0.20-0.57; p for interaction = 0.03). This large study carried out in Mediterranean women suggests that leisure time PA may play a role in modulating MBD, particularly in overweight/obese peri-/postmenopausal women...
  8. doi request reprint Fruit and vegetables consumption and breast cancer risk: the EPIC Italy study
    Giovanna Masala
    Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute ISPO, Ponte Nuovo Palazzina 28 A, Via delle Oblate 4, 50141 Florence, Italy
    Breast Cancer Res Treat 132:1127-36. 2012
    ..In this Mediterranean population, a clear protective role of increasing vegetables consumption, mainly leafy and fruiting vegetables, on BC risk emerged...
  9. doi request reprint Anthropometric and dietary determinants of blood pressure in over 7000 Mediterranean women: the European Prospective Investigation into Cancer and Nutrition-Florence cohort
    Giovanna Masala
    Molecular and Nutritional Epidemiology Unit, ISPO, Florence, Italy
    J Hypertens 26:2112-20. 2008
    ..Anthropometric characteristics and dietary habits are widely recognized to influence blood pressure. We evaluated their role in a large series of Mediterranean adult women...
  10. pmc Association between the BRCA2 N372H variant and male breast cancer risk: a population-based case-control study in Tuscany, Central Italy
    Domenico Palli
    Molecular and Nutritional Epidemiology Unit, CSPO, Scientific Institute of Tuscany, 50139 Florence, Italy
    BMC Cancer 7:170. 2007
    ..Considering the relevant role of BRCA2 in MBC, we investigated whether the BRCA2 N372H variant, representing the only common non-synonymous polymorphism in BRCA2, might modulate the risk of BC in male populations...
  11. ncbi request reprint A dietary pattern rich in olive oil and raw vegetables is associated with lower mortality in Italian elderly subjects
    Giovanna Masala
    Molecular and Nutritional Epidemiology Unit, CSPO Scientific Institute of Tuscany, Via Cosimo il Vecchio 2, 50139, Florence, Italy
    Br J Nutr 98:406-15. 2007
    ..Dietary recommendations aimed at the Italian elderly population should support a dietary pattern characterised by a high consumption of olive oil, raw vegetables and poultry...
  12. ncbi request reprint Urinary 1-hydroxypyrene and t,t-muconic acid as biomarkers of exposure to environmental pollutants in two areas in Italy (EPIC-Florence and Ragusa)
    Calogero Saieva
    Molecular and Nutritional Epidemiology Unit, CSPO, Scientific Institute of Tuscany, Florence, Italy
    Tumori 89:679-86. 2003
    ..Int J Cancer, 87: 444-451, 2000) and showed that mean DNA adduct levels varied considerably among different centers, being highest in Florence (a large metropolitan area in Tuscany) and lowest in Ragusa (a small town in Sicily)...
  13. doi request reprint A PALB2 germline mutation associated with hereditary breast cancer in Italy
    Laura Papi
    Medical Genetics Unit, Department of Clinical Physiopathology, University of Florence, Viale Pieraccini, 6, 50139 Florence, Italy
    Fam Cancer 9:181-5. 2010
    ....
  14. doi request reprint Polymorphic DNA repair and metabolic genes: a multigenic study on gastric cancer
    Domenico Palli
    Molecular and Nutritional Epidemiology Unit, ISPO Cancer Prevention and Research Institute, Via Cosimo il Vecchio 2, 50139 Florence, Italy
    Mutagenesis 25:569-75. 2010
    ..25, P=0.0012). These findings indicate that a complex interaction between host factors such as oxidative stress, antioxidant capacity and efficiency of multiple DNA repair pathways underlies the inter-individual variability in GC risk...
  15. pmc SULT1A1 gene deletion in BRCA2-associated male breast cancer: a link between genes and environmental exposures?
    Domenico Palli
    Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute ISPO, Florence, Italy
    J Cell Mol Med 17:605-7. 2013
    ....
  16. ncbi request reprint Twenty-four-hour urinary excretion of ten pesticide metabolites in healthy adults in two different areas of Italy (Florence and Ragusa)
    Calogero Saieva
    Molecular and Nutritional Epidemiology Unit, CSPO, Scientific Institute of Tuscany, Via di San Salvi 12, 50135 Florence, Italy
    Sci Total Environ 332:71-80. 2004
    ..Our results suggest that food monitoring programs should be supported by general campaigns aimed to reduce the use of pesticides in agriculture...
  17. doi request reprint Fruit, vegetables, and olive oil and risk of coronary heart disease in Italian women: the EPICOR Study
    Benedetta Bendinelli
    Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute, Florence, Italy
    Am J Clin Nutr 93:275-83. 2011
    ..Many observational studies support the recommendation to eat sufficient amounts of fruit and vegetables as part of a healthy diet...
  18. ncbi request reprint Daily consumption of a high-phenol extra-virgin olive oil reduces oxidative DNA damage in postmenopausal women
    Simonetta Salvini
    Molecular and Nutritional Epidemiology Unit, Centro per lo Studio e la Prevenzione Oncologica CSPO, Scientific Institute of Tuscany, Florence, Italy
    Br J Nutr 95:742-51. 2006
    ..Despite the small sample size, the present study showed a reduction of DNA damage by consumption of an EVOO rich in phenols, particularly hydroxytyrosol...
  19. doi request reprint Founder mutations account for the majority of BRCA1-attributable hereditary breast/ovarian cancer cases in a population from Tuscany, Central Italy
    Laura Papi
    Medical Genetics Unit, Department of Clinical Physiopathology, University of Florence, Viale Pieraccini, 6, 50139 Florence, Italy
    Breast Cancer Res Treat 117:497-504. 2009
    ..Although both genes display a highly heterogeneous mutation spectrum, a number of alterations recur in some populations. Only a limited number of founder mutations have been identified in the Italian population so far...
  20. doi request reprint Effects of de-alcoholised wines with different polyphenol content on DNA oxidative damage, gene expression of peripheral lymphocytes, and haemorheology: an intervention study in post-menopausal women
    Lisa Giovannelli
    Department of Preclinical and Clinical Pharmacology, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy
    Eur J Nutr 50:19-29. 2011
    ..The present intervention study was undertaken to evaluate the in vivo effects of wine polyphenols on gene expression in humans, along with their supposed antioxidant activity...
  21. doi request reprint Dietary and lifestyle determinants of malondialdehyde DNA adducts in a representative sample of the Florence City population
    Calogero Saieva
    Cancer Risk Factor Branch, Cancer Research and Prevention Institute ISPO, Via Cosimo il Vecchio 2, 50139 Florence, Italy and
    Mutagenesis 31:475-80. 2016
    ..049), particularly evident for the highest categories of adherence. Our results indicate that M1dG levels can be modulated by selected individual characteristics such as gender, physical activity and a Mediterranean dietary pattern. ..
  22. ncbi request reprint CagA+ Helicobacter pylori infection and gastric cancer risk in the EPIC-EURGAST study
    Domenico Palli
    Molecular and Nutritional Epidemiology Unit, CSPO, Scientific Institute of Tuscany, Florence, Italy
    Int J Cancer 120:859-67. 2007
    ..This association was limited to distal GC, while serologically defined SCAG was strongly associated with cardia GC, thus suggesting a divergent risk pattern for these 2 sites...
  23. pmc The BRCAPRO 5.0 model is a useful tool in genetic counseling and clinical management of male breast cancer cases
    Ines Zanna
    Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute ISPO, Florence, Italy
    Eur J Hum Genet 18:856-8. 2010
    ..5, 0.98, 0.97 and 0.67, respectively, for the combined probability. BRCAPRO version 5.0 can be particularly useful in dealing with non-familial MBC, a circumstance that often represents a challenging situation in genetic counseling...
  24. doi request reprint General and cancer mortality in a large cohort of Italian alcoholics
    Calogero Saieva
    Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute, Florence, Italy
    Alcohol Clin Exp Res 36:342-50. 2012
    ..This study aimed to evaluate the general and cancer mortality in a cohort of subjects with alcohol addiction residing in Tuscany (Central Italy)...
  25. pmc Glycemic index, glycemic load and mammographic breast density: the EPIC Florence longitudinal study
    Giovanna Masala
    Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute, ISPO, Florence, Italy
    PLoS ONE 8:e70943. 2013
    ..In this Italian population we observed an association between glycemic load, total and rapidly absorbed carbohydrates and high MBD. These novel results warrant further investigations...
  26. ncbi request reprint Physical activity in the EPIC-Italy centers
    Simonetta Salvini
    Molecular and Nutritional Epidemiology Unit, CSPO, Scientific Institute of Tuscany, Florence, Italy
    Tumori 89:646-55. 2003
    ..Detailed information about physical activity habits, together with a description of other characteristics, could help in designing physical activity promotion programs in different Italian populations and age groups...
  27. ncbi request reprint A gene-environment interaction between occupation and BRCA1/BRCA2 mutations in male breast cancer?
    Domenico Palli
    Molecular and Nutritional Epidemiology Unit, CSPO, Scientific Institute of Tuscany, Via di San Salvi 12, 50135 Florence, Italy
    Eur J Cancer 40:2474-9. 2004
    ....
  28. ncbi request reprint DNA bulky adducts in a Mediterranean population correlate with environmental ozone concentration, an indicator of photochemical smog
    Domenico Palli
    Molecular and Nutritional Epidemiology Unit, CSPO Scientific Institute of Tuscany, Florence, Italy
    Int J Cancer 109:17-23. 2004
    ....
  29. ncbi request reprint Dietary and lifestyle determinants of mammographic breast density. A longitudinal study in a Mediterranean population
    Giovanna Masala
    Molecular and Nutritional Epidemiology Unit, CSPO, Scientific Institute of Tuscany, Florence, Italy
    Int J Cancer 118:1782-9. 2006
    ..01). This large longitudinal study, the first carried out in Mediterranean women, suggests that specific dietary components may play a key role in determining MBD in this population, thus possibly modulating BC risk...
  30. ncbi request reprint The Florence city sample: dietary and life-style habits of a representative sample of adult residents. a comparison with the EPIC-Florence volunteers
    Giovanna Masala
    Molecular and Nutritional Epidemiology Unit, CSPO, Istituto scientifico della Regione Toscana, Florence, Italy
    Tumori 89:636-45. 2003
    ..Overall, our results suggest that the large EPIC-Florence cohort was not strictly selected and showed a total caloric intake and a range of dietary variability similar to that of the general population of the same area...
  31. ncbi request reprint GSTT1 and GSTM1 gene polymorphisms and gastric cancer in a high-risk italian population
    Domenico Palli
    Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Center CSPO, Scientific Institute of Tuscany, Florence, Italy
    Int J Cancer 115:284-9. 2005
    ..This study provides further support to the hypothesis that the risk of developing GC is influenced by inter-individual variation in both carcinogen detoxification and antioxidant capacity. (c) 2005 Wiley-Liss, Inc...