Genomes and Genes
Affiliation: Ospedale Niguarda
- Coagulation activation and long-term outcome in acute coronary syndromesDiego Ardissino
Division of Cardiology, Ospedale Niguarda Ca Grande, Milan
Blood 102:2731-5. 2003..25-2.28; RR, 1.35 and 95% CI, 1.11-1.86, respectively). After an episode of acute coronary syndrome, both high and low levels of thrombin generation are predictors of an increased risk of an unfavorable outcome...
- Effect of abciximab on prothrombin activation and thrombin generation in patients with acute myocardial infarction also receiving reteplasePiera Angelica Merlini
Division of Cardiology, Ospedale Niguarda, Milan, Italy
Am J Cardiol 93:195-8. 2004....
- Different quantitative apoptotic traits in coronary atherosclerotic plaques from patients with stable angina pectoris and acute coronary syndromesMarco L Rossi
Division of Cardiology, Istituto Clinico Humanitas, Milan, Italy
Circulation 110:1767-73. 2004..We tested the hypothesis that apoptosis is quantitatively increased in unstable atherosclerotic plaques...
- Expression of endothelial protein C receptor and thrombomodulin in human coronary atherosclerotic plaquesPiera Angelica Merlini
Division of Cardiology, Niguarda Ca Granda Hospital, Milan, Italy
Ital Heart J 5:42-7. 2004....
- Activation of the contact system and inflammation after thrombolytic therapy in patients with acute myocardial infarctionPiera Angelica Merlini
IV Division of Cardiology, Ospedale Niguarda, Milan, Italy
Am J Cardiol 93:822-5. 2004....
- Thrombocytopenia caused by abciximab or tirofiban and its association with clinical outcome in patients undergoing coronary stentingPiera Angelica Merlini
Division of Cardiology, Ospedale Niguarda, Piazza Ospedale Maggiore 1, 20162 Milan, Italy
Circulation 109:2203-6. 2004....
- Effect of Abciximab on prothrombin activation and thrombin generation in acute coronary syndromes without ST-segment elevation: Global Utilization of Strategies to Open Occluded Coronary Arteries Trial IV in Acute Coronary Syndromes (GUSTO IV ACS) ItalianPiera Angelica Merlini
Division of Cardiology, Ospedale Niguarda, Milan, Italy
Circulation 105:928-32. 2002..No data are available concerning the effect of abciximab on the in vivo markers of prothrombin activation and thrombin generation in patients with acute coronary syndromes without ST elevation...
- Impact of acute renal failure following percutaneous coronary intervention on long-term mortalityAlberto Roghi
De Gasperis Department of Cardiology, Niguarda Ca Granda Hospital, Milan, Italy
J Cardiovasc Med (Hagerstown) 9:375-81. 2008..Whether this event should be considered as a marker of disease severity or an independent contributor to mortality is still unclear...
- [Multivessel percutaneous coronary interventions. When incomplete revascularization may represent a therapeutic option]Fabrizio Ugo
UO Cardiologia, Dipartimento del Cuore, Azienda Ospedaliero Universitaria, Parma
G Ital Cardiol (Rome) 7:36S-46S. 2006....
- [Pathogenesis of acute coronary syndromes: the activated plaque]Giorgia Paoli
UO di Cardiologia, Ospedale Maggiore, Parma
Ital Heart J 6:5S-11S. 2005....
- Tirofiban in acute coronary syndromesAlberto Menozzi
Division of Cardiology, Maggiore Hospital, University of Parma, Parma, Italy
Expert Rev Cardiovasc Ther 3:193-206. 2005..In particular, the role of early, upstream tirofiban coupled with early aggressive revascularization in the management of high-risk non-ST-segment elevation acute coronary syndromes is emphasized...
- In-hospital and one-year outcomes of patients with high-risk acute myocardial infarction treated with thrombolysis or primary coronary angioplastyGiuseppe Steffenino
Department of Cardiology, S Croce e Carle Hospital, Cuneo, Italy
Ital Heart J 5:136-45. 2004..The aim of this study was to observe the outcomes of high-risk patients with acute myocardial infarction treated with primary angioplasty and intravenous thrombolysis in a community setting...
- N-terminal pro-brain natriuretic peptide on admission has prognostic value across the whole spectrum of acute coronary syndromesMarcello Galvani
Ospedale G B Morgagni and Fondazione Sacco, Forli, Italy
Circulation 110:128-34. 2004..We measured N-terminal pro-brain natriuretic peptide (NT-proBNP) on admission in patients with ACS and ECG evidence of myocardial ischemia...
- Impact of the elevation of biochemical markers of myocardial damage on long-term mortality after percutaneous coronary intervention: results of the CK-MB and PCI studyClaudio Cavallini
Ospedale Ca Foncello, Divisione di Cardiologia, Piazza Ospedale 1, 31100 Treviso, Italy
Eur Heart J 26:1494-8. 2005..In this multicentre prospective cohort study, we evaluated the influence of post-procedural elevations of CK-MB and troponin I (cTnI) on long-term mortality...
- Safety and efficacy of enoxaparin vs unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes who receive tirofiban and aspirin: a randomized controlled trialMichael A Blazing
Duke Clinical Research Institute, Durham, NC, USA
JAMA 292:55-64. 2004..It is not clear if combining enoxaparin with glycoprotein IIb/IIIa inhibitors is as safe or as effective as the current standard combination of unfractionated heparin with glycoprotein IIb/IIIa inhibitors...
- Mortality at 1 year for the direct comparison of tirofiban and abciximab during percutaneous coronary revascularization: do tirofiban and ReoPro give similar efficacy outcomes at trial 1-year follow-upDebabrata Mukherjee
Division of Cardiovascular Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY 40536 0200, USA
Eur Heart J 26:2524-8. 2005..We report here the 1-year mortality of the study population...
- [Acute coronary syndromes with ST-segment elevation: primary angioplasty]Giorgia Paoli
Dipartimento di Cardiologia, Ospedale Maggiore, Parma
Ital Heart J 4:16S-20S. 2003
- Outcomes at 6 months for the direct comparison of tirofiban and abciximab during percutaneous coronary revascularisation with stent placement: the TARGET follow-up studyDavid J Moliterno
Department of Cardiovascular Medicine and C5 Cleveland Clinic Cardiovascular Coordinating Center, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Lancet 360:355-60. 2002....
- Mortality at 1 year with combination platelet glycoprotein IIb/IIIa inhibition and reduced-dose fibrinolytic therapy vs conventional fibrinolytic therapy for acute myocardial infarction: GUSTO V randomized trialA Michael Lincoff
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
JAMA 288:2130-5. 2002..Rates of nonfatal ischemic complications were significantly diminished...
- Prasugrel versus clopidogrel in patients with acute coronary syndromesStephen D Wiviott
Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
N Engl J Med 357:2001-15. 2007..Dual-antiplatelet therapy with aspirin and a thienopyridine is a cornerstone of treatment to prevent thrombotic complications of acute coronary syndromes and percutaneous coronary intervention...
- [Low-molecular-weight heparins in acute coronary syndrome: acquired results and new perspectives]Fabrizio Ugo
U O di Cardiologia, Dipartimento del Cuore, Azienda Ospedaliero Universitaria Ospedale Maggiore, Parma
G Ital Cardiol (Rome) 7:771-9. 2006....
- Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromesJean Pierre Bassand
Eur Heart J 28:1598-660. 2007
- Percutaneous coronary intervention in patients receiving enoxaparin or unfractionated heparin after fibrinolytic therapy for ST-segment elevation myocardial infarction in the ExTRACT-TIMI 25 trialC Michael Gibson
Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
J Am Coll Cardiol 49:2238-46. 2007....
- One-year follow-up of the ASSENT-2 trial: a double-blind, randomized comparison of single-bolus tenecteplase and front-loaded alteplase in 16,949 patients with ST-elevation acute myocardial infarctionPeter Sinnaeve
Department of Cardiology, University of Leuven, Leuven, Belgium
Am Heart J 146:27-32. 2003..The aim of this study is to assess mortality rates after 1-year follow-up...
- Association between admission white blood cell count and one-year mortality in patients with acute coronary syndromesMichael H Yen
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Am J Med 115:318-21. 2003
- Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of CardiologyKim Fox
Department of Cardiology, Royal Brompton Hospital, London, UK
Eur Heart J 27:1341-81. 2006
- The thrombospondin-1 N700S polymorphism is associated with early myocardial infarction without altering von Willebrand factor multimer sizeJeffrey I Zwicker
Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Blood 108:1280-3. 2006....
- Usefulness of 64-slice multislice computed tomography coronary angiography to assess in-stent restenosisFilippo Cademartiri
Department of Radiology and Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
J Am Coll Cardiol 49:2204-10. 2007..This study sought to evaluate the diagnostic accuracy of 64-slice multislice computed tomography (MSCT) coronary angiography in the follow-up of patients with previous coronary stent implantation...
- Comparison of outcomes of patients with myocardial infarction when living alone versus those not living aloneJ Conor O'Shea
Duke Clinical Research Institute, Durham, North Carolina, USA
Am J Cardiol 90:1374-7. 2002
- [Guidelines on the management of stable angina pectoris; the experts of the European Society of Cardiology on the management of stable angina pectoris]Kim Fox
Department of Cardiology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
Kardiol Pol 64:823-80. 2006
- Effect of sirolimus-eluting stent in diabetic patients with small coronary arteries (a SES-SMART substudy)Paolo Ortolani
Institute of Cardiology, Policlinico S Orsola, University of Bologna, Bologna, Italy
Am J Cardiol 96:1393-8. 2005..In conclusion, in diabetics with small coronary arteries, SES implantation significantly reduces the incidence of the 8-month angiographic restenosis rate compared with BMSs...
- [Expert Consensus document on angiotensin converting enzyme inhibitors in cardiovascular disease]Jose Lopez-Sendon
Rev Esp Cardiol 57:1213-32. 2004
- Effectiveness of adjunctive stent implantation following directional coronary atherectomy for treatment of left anterior descending ostial stenosisEzio Bramucci
Department of Cardiology, I R C C S Policlinico San Matteo, Piazzale Golgi 2, 27100 Pavia, Italy
Am J Cardiol 90:1074-8. 2002..These results indicate that the combined approach of DCA and stent implantation is feasible and safe in patients with LAD ostial lesions, has a high success rate, a low incidence of restenosis, and a good long-term outcome...
- Management of acute myocardial infarction in patients presenting with ST-segment elevation. The Task Force on the Management of Acute Myocardial Infarction of the European Society of CardiologyFrans Van de Werf
Cardiology, Gasthuisberg University Hospital, Leuven, Belgium
Eur Heart J 24:28-66. 2003
- Risk of myocardial infarction and polymorphisms in candidate genesPier M Mannucci
N Engl J Med 348:1176-7; author reply 1176-7. 2003
- Images in cardiovascular medicine. Magnetic resonance imaging of impending left ventricular rupture after acute myocardial infarctionAntonello Zoni
Division of Cardiology, University Hospital, Parma, Italy
Circulation 108:498-9. 2003
- Vagaries of genetic association studies in myocardial infarctionPier M Mannucci
Blood 102:1558-9; author reply 1559-60. 2003
- Effectiveness of treatment of in-stent restenosis with an 8-French compatible atherectomy catheterFlavio Airoldi
EMO Centro Cuore, Columbus Clinic, Via Buonarroti 48 20145 Milan, Italy
Am J Cardiol 92:725-8. 2003..6% of patients. The secondary end point regarding the incidence of angiographic restenosis at 6 months showed a high restenosis rate (65%)...
- Angiotensin-converting enzyme insertion/deletion polymorphism and risk of restenosis after directional coronary atherectomy followed by stent implantationUmberto Canosi
Divisione di Cardiologia IRCCS Policlinico San Matteo, Piazza Golgi 2, 27100 Pavia, Italy
Thromb Haemost 91:795-800. 2004..Our results indicate that ACE I/D polymorphism does not influence the risk of developing angiographic restenosis in patients undergoing DCA followed by stent implantation...
- Plasma and urinary free 3-nitrotyrosine following cardiac angiography procedures with non-ionic radiocontrast mediaEnrico Fiaccadori
Dipartimento di Clinica Medica, Nefrologia e Scienze della Prevenzione, Universita degli Studi di Parma, Via Gramsci 14, 43100 Parma, Italy
Nephrol Dial Transplant 19:865-9. 2004..However, no study has been published showing that RCM administration elicits oxidative stress in humans...
- Sirolimus-eluting vs uncoated stents for prevention of restenosis in small coronary arteries: a randomized trialDiego Ardissino
Division of Cardiology, Ospedale Maggiore, University of Parma, Italy
JAMA 292:2727-34. 2004..Sirolimus-eluting stents reduce restenosis in simple and previously untreated lesions of large coronary arteries, but their outcomes in small vessels have not been adequately investigated...
- The prognostic value of creatine kinase elevations extends across the whole spectrum of acute coronary syndromesStefano Savonitto
Department of Cardiology, Niguarda Hospital, Milan, Italy
J Am Coll Cardiol 39:22-9. 2002..The study investigated the relationship among creatine kinase (CK) elevations, clinical characteristics and cardiac events across the whole spectrum of acute coronary syndromes (ACS)...