Affiliation: National Cancer Research Institute
- Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomasViviana Gismondi
National Cancer Institute, Largo R Benzi 10, 16132 Genoa, Italy
Int J Cancer 109:680-4. 2004..In addition, our data suggest that mutation 1395delGGA is a subpolymorphic MYH mutational event in some Caucasian populations...
- Increased risk of colorectal adenomas in Italian subjects carrying the p53 PIN3 A2-Pro72 haplotypeChiara Perfumo
Unit of Molecular Mutagenesis, National Institute for Cancer Research, Genoa, Italy
Digestion 74:228-35. 2006..Few reports have investigated the association of two p53 polymorphisms (Arg72Pro and PIN3-A2) with colorectal cancer (CRC) risk, and no previous study has analyzed their role as susceptibility alleles for colorectal adenoma...
- Cyclooxygenase-2 expression in FAP patients carrying germ line MYH mutationsMilo Frattini
Department of Experimental Oncology and Unit of Experimental Molecular Pathology, Istituto Nazionale per lo Studio e la Cura dei Tumori, Via G Venezian 1, 20133 Milan, Italy
Cancer Epidemiol Biomarkers Prev 14:2049-52. 2005....
- Multiplex tetra-primer amplification refractory mutation system PCR to detect 6 common germline mutations of the MUTYH gene associated with polyposis and colorectal cancerPatrizia Piccioli
Laboratory of Human Genetics, Medical Oncology C, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Clin Chem 52:739-43. 2006..We describe a simple tetra-primer amplification refractory mutation system PCR (T-ARMS-PCR) for detecting MUTYH mutations, which are associated with colorectal adenomas and colorectal cancer...