Ciro Indolfi

Summary

Affiliation: Magna Graecia University
Country: Italy

Publications

  1. ncbi request reprint Fludarabine prevents smooth muscle proliferation in vitro and neointimal hyperplasia in vivo through specific inhibition of STAT-1 activation
    Daniele Torella
    Laboratory of Molecular and Cellular Cardiology, Magna Graecia University, Catanzaro, Italy
    Am J Physiol Heart Circ Physiol 292:H2935-43. 2007
  2. ncbi request reprint The present and future of drug-eluting stents
    Ciro Indolfi
    Division of Cardiology, Department of Experimental and Clinical Medicine, Magna Graecia University, Catanzaro, Italy
    Ital Heart J 6:498-506. 2005
  3. ncbi request reprint Physical training increases eNOS vascular expression and activity and reduces restenosis after balloon angioplasty or arterial stenting in rats
    Ciro Indolfi
    Division of Cardiology, Magna Graecia University, Catanzaro, Italy
    Circ Res 91:1190-7. 2002
  4. doi request reprint The instantaneous wave-free ratio (iFR) for evaluation of non-culprit lesions in patients with acute coronary syndrome and multivessel disease
    Ciro Indolfi
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy URT CNR, Magna Graecia University, Catanzaro, Italy Electronic address
    Int J Cardiol 178:46-54. 2015
  5. pmc Non-coding RNAs: the "dark matter" of cardiovascular pathophysiology
    Claudio Iaconetti
    Division of Cardiology, Magna Graecia University, URT Consiglio Nazionale delle Ricerche CNR, Catanzaro 88100, Italy
    Int J Mol Sci 14:19987-20018. 2013
  6. ncbi request reprint [Mechanism of troponin and CK-MB release after percutaneous coronary interventions]
    Annalisa Mongiardo
    U O di Cardiologia Interventistica, Universita degli Studi Magna Graecia, Catanzaro
    Ital Heart J Suppl 3:270-4. 2002
  7. ncbi request reprint Polytetrafluoroethylene stent deployment for a left anterior descending coronary aneurysm complicated by late acute anterior myocardial infarction
    Ciro Indolfi
    Division of Cardiology, Magna Graecia University, Catanzaro, Italy
    Circulation 112:e70-1. 2005
  8. ncbi request reprint [Italian Consensus Conference on drug-eluting stents]
    Ciro Indolfi
    Società Italialna di Cardiologia Invasiva, Cattedra di Cardiologia, Università degli Studi Magnut Graecia, Catanzaro
    Ital Heart J Suppl 5:64-70. 2004
  9. ncbi request reprint Molecular mechanisms of in-stent restenosis and approach to therapy with eluting stents
    Ciro Indolfi
    Division of Cardiology, Magna Graecia University, Catanzaro, Italy
    Trends Cardiovasc Med 13:142-8. 2003
  10. ncbi request reprint Hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin prevents cardiac hypertrophy induced by pressure overload and inhibits p21ras activation
    Ciro Indolfi
    Division of Cardiology, Magna Graecia University, Catanzaro, Italy
    Circulation 106:2118-24. 2002

Detail Information

Publications77

  1. ncbi request reprint Fludarabine prevents smooth muscle proliferation in vitro and neointimal hyperplasia in vivo through specific inhibition of STAT-1 activation
    Daniele Torella
    Laboratory of Molecular and Cellular Cardiology, Magna Graecia University, Catanzaro, Italy
    Am J Physiol Heart Circ Physiol 292:H2935-43. 2007
    ..Fludarabine-eluting stents are feasible and effective in reducing in-stent restenosis in rabbits...
  2. ncbi request reprint The present and future of drug-eluting stents
    Ciro Indolfi
    Division of Cardiology, Department of Experimental and Clinical Medicine, Magna Graecia University, Catanzaro, Italy
    Ital Heart J 6:498-506. 2005
    ..e., nanotechnology) that will improve DES performance allowing other future clinical applications in patients with ST-elevation myocardial infarction, vulnerable plaques, insulin-dependent diabetes mellitus, etc...
  3. ncbi request reprint Physical training increases eNOS vascular expression and activity and reduces restenosis after balloon angioplasty or arterial stenting in rats
    Ciro Indolfi
    Division of Cardiology, Magna Graecia University, Catanzaro, Italy
    Circ Res 91:1190-7. 2002
    ..Increase in eNOS expression and activity might contribute to the potential beneficial effects of exercise on the vessel wall after vascular injury...
  4. doi request reprint The instantaneous wave-free ratio (iFR) for evaluation of non-culprit lesions in patients with acute coronary syndrome and multivessel disease
    Ciro Indolfi
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy URT CNR, Magna Graecia University, Catanzaro, Italy Electronic address
    Int J Cardiol 178:46-54. 2015
    ....
  5. pmc Non-coding RNAs: the "dark matter" of cardiovascular pathophysiology
    Claudio Iaconetti
    Division of Cardiology, Magna Graecia University, URT Consiglio Nazionale delle Ricerche CNR, Catanzaro 88100, Italy
    Int J Mol Sci 14:19987-20018. 2013
    ..This review outlines the current knowledge of the different ncRNA classes and summarizes their role in cardiovascular development and disease. ..
  6. ncbi request reprint [Mechanism of troponin and CK-MB release after percutaneous coronary interventions]
    Annalisa Mongiardo
    U O di Cardiologia Interventistica, Universita degli Studi Magna Graecia, Catanzaro
    Ital Heart J Suppl 3:270-4. 2002
    ..In conclusion, after successful percutaneous coronary interventions, minor elevation of troponin may occur. In this setting cardiac troponin I is a highly specific marker of myocardial injury...
  7. ncbi request reprint Polytetrafluoroethylene stent deployment for a left anterior descending coronary aneurysm complicated by late acute anterior myocardial infarction
    Ciro Indolfi
    Division of Cardiology, Magna Graecia University, Catanzaro, Italy
    Circulation 112:e70-1. 2005
  8. ncbi request reprint [Italian Consensus Conference on drug-eluting stents]
    Ciro Indolfi
    Società Italialna di Cardiologia Invasiva, Cattedra di Cardiologia, Università degli Studi Magnut Graecia, Catanzaro
    Ital Heart J Suppl 5:64-70. 2004
  9. ncbi request reprint Molecular mechanisms of in-stent restenosis and approach to therapy with eluting stents
    Ciro Indolfi
    Division of Cardiology, Magna Graecia University, Catanzaro, Italy
    Trends Cardiovasc Med 13:142-8. 2003
    ..Finally, the new concept of local drugs that elute directly to the site of vascular injury from coated stents and the available clinical results obtained with rapamycin or paclitaxel-eluting stents are discussed...
  10. ncbi request reprint Hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin prevents cardiac hypertrophy induced by pressure overload and inhibits p21ras activation
    Ciro Indolfi
    Division of Cardiology, Magna Graecia University, Catanzaro, Italy
    Circulation 106:2118-24. 2002
    ..The aims of the study were to assess the in vivo effects of simvastatin (SIM) on cardiac hypertrophy and on Ras signaling in rats with ascending aorta banding...
  11. ncbi request reprint Rat carotid artery dilation by PTCA balloon catheter induces neointima formation in presence of IEL rupture
    Ciro Indolfi
    Division of Cardiology, Magna Graecia University, Via Tommaso Campanella 115, 88100 Catanzaro, Italy
    Am J Physiol Heart Circ Physiol 283:H760-7. 2002
    ..In conclusion, our inexpensive animal model of restenosis after angioplasty may have great relevance toward a better understanding of the mechanisms and toward assessment of new therapeutical strategies for this phenomenon...
  12. doi request reprint Mitogen-activated protein kinases activation in T lymphocytes of patients with acute coronary syndromes
    Ciro Indolfi
    Division of Cardiology, Laboratory of Molecular and Cellular Cardiology, University Magna Graecia, Viale Europa, Campus S Venuta di Germaneto, Catanzaro, Italy
    Basic Res Cardiol 106:667-79. 2011
    ..These data could represent a valuable new molecular signature to be used as specific biomarkers for the diagnosis of unstable angina within ACS...
  13. doi request reprint Differential regulation of vascular smooth muscle and endothelial cell proliferation in vitro and in vivo by cAMP/PKA-activated p85alphaPI3K
    Daniele Torella
    Laboratory of Molecular and Cellular Cardiology, Magna Graecia University, Campus S Venuta, Viale Europa Germaneto, Catanzaro 88100, Italy
    Am J Physiol Heart Circ Physiol 297:H2015-25. 2009
    ..By reducing neointimal hyperplasia without inhibiting endothelial regeneration, it exerts a protective effect against restenosis after balloon injury...
  14. ncbi request reprint Aging exacerbates negative remodeling and impairs endothelial regeneration after balloon injury
    Daniele Torella
    Div of Cardiology, Magna Graecia Univ, Via Tommaso Campanella, 115, 88100 Catanzaro, Italy
    Am J Physiol Heart Circ Physiol 287:H2850-60. 2004
    ..The molecular mechanisms underlying these responses seem to be a reduced Akt and eNOS activity...
  15. pmc MicroRNA-1 downregulation increases connexin 43 displacement and induces ventricular tachyarrhythmias in rodent hypertrophic hearts
    Antonio Curcio
    Division of Cardiology, Laboratory of Molecular and Cellular Cardiology, Department of Medical and Surgical Sciences, University Magna Graecia, Catanzaro, Italy
    PLoS ONE 8:e70158. 2013
    ..Treatment of pressure overload-induced myocyte hypertrophy reduces the risk of life-threatening VT by normalizing miR-1 expression levels with the consequent stabilization of Cx43 expression and activity within the gap junction. ..
  16. doi request reprint Inhibition of miR-92a increases endothelial proliferation and migration in vitro as well as reduces neointimal proliferation in vivo after vascular injury
    Claudio Iaconetti
    Laboratory of Molecular and Cellular Cardiology, Cardiovascular Institute, Magna Graecia University, URT National Research Council, Catanzaro, Italy
    Basic Res Cardiol 107:296. 2012
    ..These data provide the first evidence that inhibition of miR-92a may represent a novel strategy to improve endothelial regeneration and reduce restenosis after vascular injury...
  17. ncbi request reprint Mechanisms of smooth muscle cell proliferation and endothelial regeneration after vascular injury and stenting: approach to therapy
    Antonio Curcio
    Division of Cardiology, Department of Experimental and Clinical Medicine, University Magna Graecia, Catanzaro, Italy
    Circ J 75:1287-96. 2011
    ..Particular emphasis will be placed on the concept that endothelial regeneration might be pursued as well as reduction of VSMC proliferation to allow stable successful revascularization after DES deployment...
  18. ncbi request reprint Coated stents: a novel approach to prevent in-stent restenosis
    Antonio Curcio
    Division of Cardiology, Magna Graecia University, Catanzaro, Naples, Italy
    Ital Heart J 3:16S-19S. 2002
  19. ncbi request reprint Effect of stent coating alone on in vitro vascular smooth muscle cell proliferation and apoptosis
    Antonio Curcio
    Div of Cardiology, Dept of Experimental and Clinical Medicine, Magna Graecia Univ, Via Tommaso Campanella 115, 88100 Catanzaro, Italy
    Am J Physiol Heart Circ Physiol 286:H902-8. 2004
    ..This effect should be taken in account when evaluating an association of this coating with antiproliferative agents for in-stent restenosis prevention...
  20. pmc Modulation of Circulating MicroRNAs Levels during the Switch from Clopidogrel to Ticagrelor
    Annarita Carino
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Græcia University, 88100 Catanzaro, Italy
    Biomed Res Int 2016:3968206. 2016
    ..If confirmed in larger, independent cohorts, our results pave the way for the use of circulating microRNAs as biomarkers of platelets activity in response to specific pharmacological treatments. ..
  21. pmc The duration of balloon inflation affects the luminal diameter of coronary segments after bioresorbable vascular scaffolds deployment
    Sabato Sorrentino
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
    BMC Cardiovasc Disord 15:169. 2015
    ..However, since no evidences are available demonstrating the superiority of a longer balloon dilatation time, the implantation technique is highly variable among different centers...
  22. doi request reprint MicroRNA-133 controls vascular smooth muscle cell phenotypic switch in vitro and vascular remodeling in vivo
    Daniele Torella
    Cardiovascular Institute, Laboratory of Molecular and Cellular Cardiology, Department of Experimental and Clinical Medicine, Magna Graecia University, Germaneto, Catanzaro, Italy
    Circ Res 109:880-93. 2011
    ..MicroRNA (miR)-1 and -133 play a crucial role in skeletal and cardiac muscle biology and pathophysiology. However, their expression and regulation in vascular cell physiology and disease is currently unknown...
  23. doi request reprint Administration of a loading dose has no additive effect on platelet aggregation during the switch from ongoing clopidogrel treatment to ticagrelor in patients with acute coronary syndrome
    Gianluca Caiazzo
    From the Division of Cardiology, Department of Medical and Surgical Sciences G C, S D R, D T, C S, A M, S G, M M, C I and Clinical Pathology Unit, Department of Health Sciences E P, E G, Magna Graecia University of Catanzaro, Catanzaro, Italy and URT CNR, Department of Medicine, Consiglio Nazionale delle Ricerche, Catanzaro, Italy C I
    Circ Cardiovasc Interv 7:104-12. 2014
    ....
  24. pmc Clinical and Procedural Outcomes of 5-French versus 6-French Sheaths in Transradial Coronary Interventions
    Alberto Polimeni
    From the Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University AP, FP, SDR, SS, DT, CS, AM, CI and URT CNR, Department of Medicine, Consiglio Nazionale delle Ricerche, Catanzaro, Italy CI
    Medicine (Baltimore) 94:e2170. 2015
    ..Results of the present meta-analysis confirm the excellent safety profile of transradial procedures both with 5-Fr and 6-Fr system. A 5-Fr system could be preferred in patients with a higher bleeding propensity or kidney injury...
  25. doi request reprint Down-regulation of miR-23b induces phenotypic switching of vascular smooth muscle cells in vitro and in vivo
    Claudio Iaconetti
    Laboratory of Molecular and Cellular Cardiology, Cardiovascular Institute, Magna Graecia University, Catanzaro, Italy
    Cardiovasc Res 107:522-33. 2015
    ..However, the role of miR-23b in vascular disease is currently unknown. Thus, the aim of the present study was to evaluate the role of miR-23b on VSMC phenotypic switch in vitro and after vascular injury in vivo...
  26. pmc Delayed sudden radial artery rupture after left transradial coronary catheterization: a case report
    Ciro Indolfi
    From the Division of Cardiology CI, FP, AM, CS, DT, SS, AP, VE, AC, SDR, Department of Medical and Surgical Sciences, Magna Graecia University and URT CNR CI, Department of Medicine, Consiglio Nazionale delle Ricerche, Catanzaro, Italy
    Medicine (Baltimore) 94:e634. 2015
    ..After prompt surgical hemostasis, negative pressure wound therapy was very helpful in favoring healing of the large and deep wound...
  27. doi request reprint Routine ganglionic plexi ablation during Maze procedure improves hospital and early follow-up results of mitral surgery
    Francesco Onorati
    Cardiac Surgery Unit, Magna Graecia University of Catanzaro, Catanzaro, Italy
    J Thorac Cardiovasc Surg 136:408-18. 2008
    ..Ganglionic plexi are claimed to be potentially responsible for atrial fibrillation. We evaluated whether ganglionic plexi isolation improves the results of the Maze procedure during mitral valve surgery...
  28. ncbi request reprint Proteomics reveals high levels of vitamin D binding protein in myocardial infarction
    Cosimo Gasparri
    Division of Cardiology, Magna Graecia University, Catanzaro, Italy
    Front Biosci (Elite Ed) 2:796-804. 2010
    ..Moreover, fresh thrombotic plaques, obtained during primary angioplasty, showed high expression of VDB protein. Mechanistically, VDB protein reduces platelet aggregation and prolongs coagulation time ex vivo...
  29. doi request reprint Clinical Usefulness of a Mobile Application for the Appropriate Selection of the Antiarrhythmic Device in Heart Failure
    Antonio Curcio
    Division of Cardiology, Department of Medical and Surgical Sciences, University Magna Graecia, Campus di Germaneto, Catanzaro, Italy
    Pacing Clin Electrophysiol 39:696-702. 2016
    ..In this setting, limited information exists about the role of medical applications in helping physicians to choose the most useful device...
  30. doi request reprint Optical coherence tomography guidance for percutaneous coronary intervention with bioresorbable scaffolds
    Gianluca Caiazzo
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Græcia University, Catanzaro, Italy National Institute of Health Research Cardiovascular Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom
    Int J Cardiol 221:352-8. 2016
    ....
  31. pmc Efficacy and Safety of Non-Vitamin K Antagonist Oral Anticoagulants versus Vitamin K Antagonist Oral Anticoagulants in Patients Undergoing Radiofrequency Catheter Ablation of Atrial Fibrillation: A Meta-Analysis
    Giuseppe Santarpia
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
    PLoS ONE 10:e0126512. 2015
    ..However efficacy and safety of NOACs in patients undergoing catheter ablation (RFCA) of AF has not been well established yet...
  32. pmc Carbonic anhydrase activation is associated with worsened pathological remodeling in human ischemic diabetic cardiomyopathy
    Daniele Torella
    Molecular and Cellular Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
    J Am Heart Assoc 3:e000434. 2014
    ..Recently, carbonic anhydrases (CAs) have been shown to play a major role in diabetic microangiopathy but their role in the diabetic cardiomyopathy is still unknown...
  33. ncbi request reprint Drug-eluting stents versus bare metal stents in percutaneous coronary interventions (a meta-analysis)
    Ciro Indolfi
    Division of Cardiology, Medical School, University Magna Graecia, Catanzaro, Italy
    Am J Cardiol 95:1146-52. 2005
    ..23, 95% CI 0.15 to 0.35) and paclitaxel-eluting stents (RR 0.39, 95% CIl 0.29 to 0.53)...
  34. ncbi request reprint Molecular mechanisms of restenosis after percutaneous peripheral angioplasty and approach to endovascular therapy
    Annalisa Mongiardo
    Cattedra di Cardiologia, Università Magna Graecia, Catanzaro, Italy
    Curr Drug Targets Cardiovasc Haematol Disord 4:275-87. 2004
    ..The results at 6 months demonstrate inhibition of in-stent neointimal proliferation, reflecting a trend toward a reduction in late loss...
  35. ncbi request reprint Cardiac stem cell-based myocardial regeneration: towards a translational approach
    Daniele Torella
    Laboratory of Molecular, and Cellular Cardiology, Department of Experimental and Clinical Medicine, Magna Graecia University, Magna Graecia University, Catanaro 88100, Catanzaro 88100, Italy
    Cardiovasc Hematol Agents Med Chem 6:53-9. 2008
    ..The present review highlights current knowledge on the biology of CSCs and the prospects of CSC activation in situ, without the need for cell expansion in vitro and consequent transplantation...
  36. doi request reprint Vascular miRNAs after balloon angioplasty
    Alberto Polimeni
    Alberto Polimeni, Salvatore De Rosa, and Ciro Indolfi are at the Division of Cardiology, Magna Graecia University, URT Consiglio Nazionale delle Ricerche CNR, Catanzaro 88100, Italy
    Trends Cardiovasc Med 23:9-14. 2013
    ..Therefore, the goal of this review is to summarize recent experimental evidences on the role played by miRNAs in vascular remodeling, and particularly on VSMC phenotype switch and in endothelial cells, in response to vascular injury...
  37. ncbi request reprint Sirolimus-eluting vs uncoated stents for prevention of restenosis in small coronary arteries: a randomized trial
    Diego Ardissino
    Division of Cardiology, Ospedale Maggiore, University of Parma, Italy
    JAMA 292:2727-34. 2004
    ..Sirolimus-eluting stents reduce restenosis in simple and previously untreated lesions of large coronary arteries, but their outcomes in small vessels have not been adequately investigated...
  38. ncbi request reprint Immediate and long-term outcome of recanalization of chronic total coronary occlusions
    Federico Piscione
    Division of Cardiology, Federico II University, Via S Pansini 5, 80131 Naples, Italy
    J Interv Cardiol 15:173-9. 2002
    ..Family history of CAD and occlusion of left anterior descending or right coronary arteries are independent predictors of procedural success...
  39. doi request reprint Impact of intracoronary adenosine administration during primary PCI: A meta-analysis
    Alberto Polimeni
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
    Int J Cardiol 203:1032-41. 2016
    ..Aim of the present study was to evaluate all randomized trials, comparing intracoronary adenosine versus placebo in STEMI patients undergoing primary PCI...
  40. doi request reprint Left radial access for percutaneous coronary procedures: from neglected to performer? A meta-analysis of 14 studies including 7,603 procedures
    Salvatore De Rosa
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
    Int J Cardiol 171:66-72. 2014
    ..For this reason, the aim of the present meta-analysis was to compare procedural performance of left and right radial artery access for percutaneous coronary interventions...
  41. pmc Outcome of open and endovascular repair in acute type B aortic dissection: a retrospective and observational study
    Pasquale Mastroroberto
    Department of Experimental and Clinical Medicine, Cardiovascular Surgery Unit University Magna Graecia, Viale Europa, 88100 Catanzaro, Italy
    J Cardiothorac Surg 5:23. 2010
    ..The aim of the study was to analyze surgical and endovascular results in the treatment of acute type B aortic dissection (B AAD)...
  42. ncbi request reprint Cardiac stem and progenitor cell biology for regenerative medicine
    Daniele Torella
    Division of Cardiology, Magna Graecia University, Catanzaro, Italy
    Trends Cardiovasc Med 15:229-36. 2005
    ..This will enable us to design better protocols for the regeneration of functional contractile mass after myocardial injury...
  43. ncbi request reprint Pathophysiology of aortic stenosis and approach to treatment with percutaneous valve implantation
    Carmen Spaccarotella
    Department of Cardiology, University Magna Graecia, Catanzaro, Italy
    Circ J 75:11-19. 2011
    ....
  44. ncbi request reprint Early detection of progressive renal dysfunction in patients with coronary artery disease
    Giorgio Fuiano
    Departments of Nephrology, and Cardiology, University Magna Graecia of Catanzaro, Italy
    Kidney Int 68:2773-80. 2005
    ..This study was aimed at evaluating early abnormalities and outcome of renal function in CAD patients...
  45. doi request reprint Exosomal miRNAs in Heart Disease
    Claudio Iaconetti
    Laboratory of Molecular and Cellular Cardiology, Cardiovascular Institute, Magna Graecia University, Catanzaro, Italy and
    Physiology (Bethesda) 31:16-24. 2016
    ..This review addresses the functional role played by exosomal miRNAs in heart disease and their potential use as new biomarkers. ..
  46. doi request reprint Intracoronary abciximab reduces death and major adverse cardiovascular events in acute coronary syndromes: a meta-analysis of clinical trials
    Salvatore De Rosa
    Division of Cardiology, Magna Graecia University of Catanzaro, Italy
    Int J Cardiol 168:1298-305. 2013
    ..However clinical trials have shown conflicting results. The aim of the present study was to compare IC with IV abciximab administration on mortality and MACEs in patients with ACS undergoing PCI...
  47. doi request reprint Effects of successful percutaneous lower extremity revascularization on cardiovascular outcome in patients with peripheral arterial disease
    Giuseppe Giugliano
    Division of Cardiology, Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Naples, Italy
    Int J Cardiol 167:2566-71. 2013
    ..Endovascular revascularization of LE-PAD improves walking performance and quality of life. In the present study, we determined whether successful lower limbs revascularization also impacts cardiovascular outcome in LE-PAD patients...
  48. doi request reprint Effects of ambrisentan in a patient affected by combined pulmonary fibrosis and emphysema and by severe pulmonary hypertension: clinical, functional, and biomolecular findings
    Fernando Roccia
    Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy
    Clin Drug Investig 33:451-7. 2013
    ..In conclusion, we hypothesize that the clinical benefits induced by ambrisentan in this patient with CPFE can be attributed to its vasodilator and anti-proliferative actions, exerted on pulmonary the vascular bed and lung fibroblasts...
  49. doi request reprint OFFgel-based multidimensional LC-MS/MS approach to the cataloguing of the human platelet proteome for an interactomic profile
    Shibu Krishnan
    Laboratory of Proteomics and Mass Spectrometry and Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, Catanzaro, Italy
    Electrophoresis 32:686-95. 2011
    ..Moreover, toxicity pathway in agreement with network analysis, supports the concept that platelet life span is governed by an apoptotic mechanism...
  50. ncbi request reprint Transbrachial intraaortic balloon pumping in severe peripheral atherosclerosis
    Francesco Onorati
    Cardiac Surgery Unit, Magna Graecia University, Catanzaro, Italy
    Ann Thorac Surg 84:264-6. 2007
    ..Transbrachial intraaortic balloon pumping with a 7.5F catheter is as safe and effective as the transfemoral method in patients with unavailable femoral arteries...
  51. doi request reprint HMGA1 is a novel candidate gene for myocardial infarction susceptibility
    Salvatore De Rosa
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
    Int J Cardiol . 2016
    ..An association of the HMGA1 rs146052672 variant with T2DM has been recently reported. Thus, our aim was to evaluate whether this variant was also associated with AMI...
  52. doi request reprint The Brugada Syndrome - From Gene to Therapy
    Antonio Curcio
    Division of Cardiology, Department of Medical and Surgical Sciences, University Magna Graecia, Campus di Germaneto
    Circ J . 2017
    ....
  53. doi request reprint Absorb bioresorbable vascular scaffold: What have we learned after 5 years of clinical experience?
    Gianluca Caiazzo
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy Cardiovascular National Institute of Health Research Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom
    Int J Cardiol 201:129-36. 2015
    ..The aim of this review article is to critically evaluate the results of the available Absorb BVS studies and discuss the lessons learned to optimize lesion selection and implantation technique of such devices. ..
  54. doi request reprint MicroRNAs for Restenosis and Thrombosis After Vascular Injury
    Clarice Gareri
    From the Department of Medicine, Duke University, Durham, NC C G Division of Cardiology, Department of Medical and Surgical Science, Magna Graecia University, Catanzaro, Italy S D R, C I and URT CNR, Department of Medicine, URT of Consiglio Nazionale delle Ricerche, Catanzaro, Italy C I
    Circ Res 118:1170-84. 2016
    ..Application of circulating microRNAs as potential biomarkers is also discussed. ..
  55. doi request reprint Clinical significance of non-vitamin K antagonist oral anticoagulants in the management of atrial fibrillation
    Giuseppe Santarpia
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University
    Circ J 79:914-23. 2015
    ..Finally, it focuses on NOAC-related bleeding management in the setting of non-cardiac surgery or radiofrequency catheter ablation of NVAF...
  56. ncbi request reprint Emerging role of microRNAs in cardiovascular diseases
    Salvatore De Rosa
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University
    Circ J 78:567-75. 2014
    ....
  57. ncbi request reprint Renal sympathetic denervation for treating resistant hypertension
    Alberto Polimeni
    Division of Cardiology, Laboratory of Molecular and Cellular Cardiology, Department of Medical and Surgical Sciences, Catanzaro, Italy
    Circ J 77:857-63. 2013
    ..Suggestions regarding targets for future systemic hypertension management are also described...
  58. doi request reprint Aortic and left ventricular remodeling in patients with bicuspid aortic valve without significant valvular dysfunction: a prospective study
    Giuseppe Santarpia
    Cardiology Department, Magna Graecia University, Catanzaro, Italy
    Int J Cardiol 158:347-52. 2012
    ....
  59. doi request reprint Bioresorbable vascular scaffolds - basic concepts and clinical outcome
    Ciro Indolfi
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro 88100, Italy
    Nat Rev Cardiol 13:719-729. 2016
    ..Finally, all the available data on the safety profile of BVS regarding scaffold thrombosis are discussed...
  60. doi request reprint Clinical Presentation and Outcome of Brugada Syndrome Diagnosed With the New 2013 Criteria
    Antonio Curcio
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
    J Cardiovasc Electrophysiol 27:937-43. 2016
    ..This study was aimed at assessing the role of High-ICS in the analysis of BrS and the clinical profile of the patients diagnosed only when ECG leads are moved to upper intercostal spaces...
  61. pmc Fully automated software for mitral annulus evaluation in chronic mitral regurgitation by 3-dimensional transesophageal echocardiography
    Iolanda Aquila
    aCardiology Department, Ramon y Cajal University Hospital, Madrid, Spain bCardiovascular Institute, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
    Medicine (Baltimore) 95:e5387. 2016
    ..This analysis allows a better characterization of MR pathophysiology and could be useful in designing new devices for MR repair or replacement...
  62. doi request reprint A framework for the atrial fibrillation prediction in electrophysiological studies
    Patrizia Vizza
    Department of Medical and Surgical Sciences, Magna Graecia University of Catanzaro, Italy
    Comput Methods Programs Biomed 120:65-76. 2015
    ..e., not inducted) fibrillation. Profiling such signal patterns allowed to design and implement an AFib prediction algorithm able to early identify a spontaneous fibrillation. The objective is to increase the reliability of EPS procedures...
  63. doi request reprint Circulating microRNAs as Biomarkers in Cardiovascular Diseases
    Salvatore De Rosa
    Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
    EXS 106:139-49. 2015
    ....
  64. pmc Endovascular repair for acute traumatic transection of the descending thoracic aorta: experience of a single centre with a 12-years follow up
    Raffaele Serra
    Interuniversity Center of Phlebolymphology CIFL International Research and Educational Program in Clinical and Experimental Biotechnology Headquarters University Magna Graecia of Catanzaro, Viale Europa, Catanzaro, 88100, Italy
    J Cardiothorac Surg 10:171. 2015
    ..Aim of this article is to review our experience with endovascular approach for the treatment of acute traumatic rupture of descending thoracic aorta...
  65. doi request reprint Italian Diffuse/Multivessel Disease ABSORB Prospective Registry (IT-DISAPPEARS). Study design and rationale
    Luca Testa
    Istituto Clinico S Ambrogio, Milan, Italy TL, BF, La Sapienza Univ, Roma, Italy BZG, European Hospital, Rome TF, University of Verona, Verona, Italy RF, Magna Grecia Univ, Catanzaro, Italy IC Ferrarotto Hospital, Catania, Italy, TC, Centro Cardiologico Monzino, Milan, Italy BA Pisa Univ, Pisa, Italy PAS, DCM
    J Cardiovasc Med (Hagerstown) 16:253-8. 2015
    ..However, these pieces of evidence come from 'studies in which the majority of the patients had low-risk stenoses', whereas patients with more complex coronary artery disease could benefit the most from the Absorb BVS technology...
  66. doi request reprint EGFR trans-activation by urotensin II receptor is mediated by β-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy
    Giovanni Esposito
    Division of Cardiology, Federico II University of Naples, Via Pansini 5, Naples, Italy
    Basic Res Cardiol 106:577-89. 2011
    ..Our data show, for the first time in vivo, a new UTR signalling pathway which is mediated by EGFR trans-activation, dependent by β-arrestin 1/2, promoting cell survival and cardioprotection...
  67. ncbi request reprint Biomarker discovery by plasma proteomics in familial Brugada Syndrome
    M Di Domenico
    Department of Experimental and Clinical Medicine, University of Magna Graecia, Germaneto University Campus, 88100 Catanzaro, Italy
    Front Biosci (Landmark Ed) 18:564-71. 2013
    ..On the light of these results, we hypothesize that these proteins might be considered as potential markers for the identification of disease status in BS...
  68. pmc The margination propensity of spherical particles for vascular targeting in the microcirculation
    Francesco Gentile
    Center of Bio Nanotechnology and Engineering for Medicine University of Magna Graecia at Catanzaro, Viale Europa Loc, Germaneto, 88100, Catanzaro, Italy
    J Nanobiotechnology 6:9. 2008
    ....
  69. ncbi request reprint Increased vascular endothelial growth factor expression but impaired vascular endothelial growth factor receptor signaling in the myocardium of type 2 diabetic patients with chronic coronary heart disease
    Ferdinando Carlo Sasso
    Department of Geriatrics and Metabolic Disease, Second University of Naples, Naples, Italy
    J Am Coll Cardiol 46:827-34. 2005
    ..The aim of the present study was to evaluate the expression and the activity of vascular endothelial growth factor (VEGF) in the hearts of diabetic patients with chronic coronary heart disease (CHD)...
  70. ncbi request reprint Effect of sirolimus-eluting stent in diabetic patients with small coronary arteries (a SES-SMART substudy)
    Paolo Ortolani
    Institute of Cardiology, Policlinico S Orsola, University of Bologna, Bologna, Italy
    Am J Cardiol 96:1393-8. 2005
    ..In conclusion, in diabetics with small coronary arteries, SES implantation significantly reduces the incidence of the 8-month angiographic restenosis rate compared with BMSs...
  71. ncbi request reprint Comparison between four-slice computed tomography and coronary angiography for the assessment of coronary stents
    Pietro Mazzarotto
    U O Cardiologia invasiva e interventistica endovascolare, Ospedale S Carlo I D I, Rome, Italy
    J Cardiovasc Med (Hagerstown) 7:328-34. 2006
    ....
  72. ncbi request reprint Simvastatin reduces neointimal thickening after experimental angioplasty
    Ciro Indolfi
    Circulation 107:e25. 2003
  73. ncbi request reprint Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice
    Monica Fedele
    Istituto di Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche c o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Universita di Napoli Federico II, Italy
    Cancer Res 66:2536-43. 2006
    ..Therefore, the data reported here indicate the critical role of HMGA1 in heart development and growth, and reveal an unsuspected antioncogenic potential for this gene in hematologic malignancies...
  74. doi request reprint Early aggressive vs. initially conservative treatment in elderly patients with non-ST-elevation acute coronary syndrome: the Italian Elderly ACS study
    Stefano Savonitto
    Angelo De Gasperis Department of Cardiology, Niguarda Ca Granda Hospital, Milan, Italy
    J Cardiovasc Med (Hagerstown) 9:217-26. 2008
    ..Despite their high-risk characteristics and worse outcomes, compared with younger patients, the elderly receive less aggressive treatments, also due to less clear evidence regarding the most effective treatment strategy...
  75. ncbi request reprint Combined Abciximab REteplase Stent Study in acute myocardial infarction (CARESS in AMI)
    Carlo Di Mario
    Royal Brompton Hospital, London, United Kingdom
    Am Heart J 148:378-85. 2004
    ..If a mechanical recanalization is likely to be performed in an emergency, it is probably desirable that the patient receives abciximab, the glycoprotein IIb/IIIa antagonist with the strongest evidence of benefit for angioplasty in AMI...
  76. ncbi request reprint Transient and reversible deoxyribonucleic acid damage in human left ventricle under controlled ischemia and reperfusion
    Gian G Corbucci
    Division of Anesthesiology, University of Cagliari, Cagliari, Italy
    J Am Coll Cardiol 43:1992-9. 2004
    ....
  77. pmc Acute beta-adrenergic overload produces myocyte damage through calcium leakage from the ryanodine receptor 2 but spares cardiac stem cells
    Georgina M Ellison
    Zena and Michael A Wiener Cardiovascular Institute and Marie Josee and Henry R Kravis Center for Cardiovascular Health, Mount Sinai School of Medicine, New York, New York 10029, USA
    J Biol Chem 282:11397-409. 2007
    ..The latter could contribute to the ability of the myocardium to rapidly recover from acute hyperadrenergic damage...