Roberto William Invernizzi

Summary

Affiliation: Istituto di Ricerche Farmacologiche Mario Negri
Country: Italy

Publications

  1. ncbi request reprint The alpha 2-adrenoceptor antagonist idazoxan reverses catalepsy induced by haloperidol in rats independent of striatal dopamine release: role of serotonergic mechanisms
    Roberto W Invernizzi
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milan, Italy
    Neuropsychopharmacology 28:872-9. 2003
  2. pmc Flibanserin, a potential antidepressant drug, lowers 5-HT and raises dopamine and noradrenaline in the rat prefrontal cortex dialysate: role of 5-HT(1A) receptors
    Roberto William Invernizzi
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milano, Italy
    Br J Pharmacol 139:1281-8. 2003
  3. ncbi request reprint Role of presynaptic alpha2-adrenoceptors in antidepressant action: recent findings from microdialysis studies
    Roberto W Invernizzi
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milano, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 28:819-27. 2004
  4. ncbi request reprint Role of TPH-2 in brain function: news from behavioral and pharmacologic studies
    Roberto W Invernizzi
    Laboratory of Neurochemistry and Behavior, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    J Neurosci Res 85:3030-5. 2007
  5. pmc Lovastatin fails to improve motor performance and survival in methyl-CpG-binding protein2-null mice
    Claudia Villani
    Laboratory of Neurochemistry and Behaviour, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    elife 5:. 2016
  6. doi request reprint Tph2 gene deletion enhances amphetamine-induced hypermotility: effect of 5-HT restoration and role of striatal noradrenaline release
    Mirjana Carli
    Department of Neuroscience, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Lab Neurochemistry and Behavior, Milano, Italy
    J Neurochem 135:674-85. 2015

Collaborators

  • Claudia Villani
  • Mirjana Carli
  • Giuseppina Sacchetti
  • Federica Fusco
  • Alice Passoni
  • Renzo Bagnati
  • Alessia Anastasia
  • Pierangela Mainolfi
  • Chrysaugi Kostoula

Detail Information

Publications6

  1. ncbi request reprint The alpha 2-adrenoceptor antagonist idazoxan reverses catalepsy induced by haloperidol in rats independent of striatal dopamine release: role of serotonergic mechanisms
    Roberto W Invernizzi
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milan, Italy
    Neuropsychopharmacology 28:872-9. 2003
    ..1 mg/kg s.c.) did not affect the anticataleptic effect of idazoxan. The results suggest that idazoxan reversed haloperidol-induced catalepsy by a mechanism involving blockade of alpha(2)-adrenoceptors and, at least in part, 5-HT neurons...
  2. pmc Flibanserin, a potential antidepressant drug, lowers 5-HT and raises dopamine and noradrenaline in the rat prefrontal cortex dialysate: role of 5-HT(1A) receptors
    Roberto William Invernizzi
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milano, Italy
    Br J Pharmacol 139:1281-8. 2003
    ..WAY100,635 by itself had no effect on cortical extracellular monoamines. (4) The results show that the stimulation of 5-HT(1A) receptors plays a major role in the effect of flibanserin on brain extracellular 5-HT, DA and NA...
  3. ncbi request reprint Role of presynaptic alpha2-adrenoceptors in antidepressant action: recent findings from microdialysis studies
    Roberto W Invernizzi
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milano, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 28:819-27. 2004
    ..Finally, they suggest that co-administration of an alpha(2)-adrenoceptor antagonist may improve the therapeutic effect of NRI...
  4. ncbi request reprint Role of TPH-2 in brain function: news from behavioral and pharmacologic studies
    Roberto W Invernizzi
    Laboratory of Neurochemistry and Behavior, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    J Neurosci Res 85:3030-5. 2007
    ..Strain comparison might be a useful strategy to investigate the genotype-dependent alterations of TPH-2...
  5. pmc Lovastatin fails to improve motor performance and survival in methyl-CpG-binding protein2-null mice
    Claudia Villani
    Laboratory of Neurochemistry and Behaviour, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    elife 5:. 2016
    ..i>Mecp2-null mice suggests the occurrence of changes in brain cholesterol metabolism and the potential utility of using plasma levels of 24S-OHC as a biomarker of brain cholesterol homeostasis in RTT...
  6. doi request reprint Tph2 gene deletion enhances amphetamine-induced hypermotility: effect of 5-HT restoration and role of striatal noradrenaline release
    Mirjana Carli
    Department of Neuroscience, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Lab Neurochemistry and Behavior, Milano, Italy
    J Neurochem 135:674-85. 2015
    ..This suggests that Tph2(-/-) mice is a useful preclinical model to assess the role of 5-HT-dependent mechanisms in psychostimulants action. Tph2, tryptophan hydroxylase-2...