Marina Giuliano

Summary

Affiliation: Istituto Superiore di Sanit
Country: Italy

Publications

  1. ncbi request reprint Triple antiretroviral prophylaxis administered during pregnancy and after delivery significantly reduces breast milk viral load: a study within the Drug Resource Enhancement Against AIDS and Malnutrition Program
    Marina Giuliano
    Department of Drug Research and Evaluation, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Acquir Immune Defic Syndr 44:286-91. 2007
  2. doi request reprint Modifications of residual viraemia in human immunodeficiency virus-1-infected subjects undergoing repeated highly active antiretroviral therapy interruptions
    Lucia Palmisano
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    J Med Microbiol 58:121-4. 2009
  3. doi request reprint Comparison of HIV type 1 sequences from plasma, cell-free breast milk, and cell-associated breast milk viral populations in treated and untreated women in Mozambique
    Mauro Andreotti
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    AIDS Res Hum Retroviruses 25:707-11. 2009
  4. doi request reprint Nonnucleoside reverse transcriptase inhibitor concentrations during treatment interruptions and the emergence of resistance: a substudy of the ISS-PART Trial
    Maria Pirillo
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    AIDS Res Hum Retroviruses 26:541-5. 2010
  5. doi request reprint Single-nucleotide polymorphisms in human beta-defensin-1 gene in Mozambican HIV-1-infected women and correlation with virologic parameters
    Silvia Baroncelli
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    AIDS 22:1515-7. 2008
  6. doi request reprint Microbial translocation is associated with residual viral replication in HAART-treated HIV+ subjects with <50copies/ml HIV-1 RNA
    Silvia Baroncelli
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    J Clin Virol 46:367-70. 2009
  7. ncbi request reprint Determinants of virologic and immunologic outcomes in chronically HIV-infected subjects undergoing repeated treatment interruptions: the Istituto Superiore di Sanita-Pulsed Antiretroviral Therapy (ISS-PART) study
    Lucia Palmisano
    Department of Drug Research and Evaluation, Instituto Superiore di Sanita, Rome, Italy
    J Acquir Immune Defic Syndr 46:39-47. 2007
  8. pmc Maternal antiretroviral therapy for the prevention of mother-to-child transmission of HIV in Malawi: maternal and infant outcomes two years after delivery
    Marina Giuliano
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    PLoS ONE 8:e68950. 2013
  9. doi request reprint Antibodies against pneumococcal capsular polysaccharide in Malawian HIV-positive mothers and their HIV-exposed uninfected children
    Silvia Baroncelli
    a Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    Infect Dis (Lond) 48:317-321. 2016
  10. ncbi request reprint Levels of bone markers in a population of infants exposed in utero and during breastfeeding to tenofovir within an Option B+ programme in Malawi
    Marco Floridia
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    J Antimicrob Chemother 71:3206-3211. 2016

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Triple antiretroviral prophylaxis administered during pregnancy and after delivery significantly reduces breast milk viral load: a study within the Drug Resource Enhancement Against AIDS and Malnutrition Program
    Marina Giuliano
    Department of Drug Research and Evaluation, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Acquir Immune Defic Syndr 44:286-91. 2007
    ..In this study, we assessed the effect of antiretroviral treatment on breast milk viral load and determined plasma and breast milk drug concentrations in pregnant women receiving highly active antiretroviral therapy (HAART)...
  2. doi request reprint Modifications of residual viraemia in human immunodeficiency virus-1-infected subjects undergoing repeated highly active antiretroviral therapy interruptions
    Lucia Palmisano
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    J Med Microbiol 58:121-4. 2009
    ..1 copies ml(-1) (range -80 to +46.8) in arm B (P=0.024). These results suggest that intermittent HAART tends to modify HIV-1 viraemia set point even if a virological response is achieved after HAART reinstitution...
  3. doi request reprint Comparison of HIV type 1 sequences from plasma, cell-free breast milk, and cell-associated breast milk viral populations in treated and untreated women in Mozambique
    Mauro Andreotti
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    AIDS Res Hum Retroviruses 25:707-11. 2009
    ..Our data support the hypothesis of the presence of an actively replicating viral population in the breast milk compartment, distinct from that present in plasma...
  4. doi request reprint Nonnucleoside reverse transcriptase inhibitor concentrations during treatment interruptions and the emergence of resistance: a substudy of the ISS-PART Trial
    Maria Pirillo
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    AIDS Res Hum Retroviruses 26:541-5. 2010
    ....
  5. doi request reprint Single-nucleotide polymorphisms in human beta-defensin-1 gene in Mozambican HIV-1-infected women and correlation with virologic parameters
    Silvia Baroncelli
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    AIDS 22:1515-7. 2008
    ....
  6. doi request reprint Microbial translocation is associated with residual viral replication in HAART-treated HIV+ subjects with <50copies/ml HIV-1 RNA
    Silvia Baroncelli
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    J Clin Virol 46:367-70. 2009
    ..Recent data have shown that plasma levels of lipopolysaccharide (LPS) are a quantitative indicator of microbial translocation in HIV infected individuals...
  7. ncbi request reprint Determinants of virologic and immunologic outcomes in chronically HIV-infected subjects undergoing repeated treatment interruptions: the Istituto Superiore di Sanita-Pulsed Antiretroviral Therapy (ISS-PART) study
    Lucia Palmisano
    Department of Drug Research and Evaluation, Instituto Superiore di Sanita, Rome, Italy
    J Acquir Immune Defic Syndr 46:39-47. 2007
    ..Factors influencing the outcome of structured treatment interruptions (STIs) in HIV chronic infection are not fully elucidated...
  8. pmc Maternal antiretroviral therapy for the prevention of mother-to-child transmission of HIV in Malawi: maternal and infant outcomes two years after delivery
    Marina Giuliano
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    PLoS ONE 8:e68950. 2013
    ....
  9. doi request reprint Antibodies against pneumococcal capsular polysaccharide in Malawian HIV-positive mothers and their HIV-exposed uninfected children
    Silvia Baroncelli
    a Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    Infect Dis (Lond) 48:317-321. 2016
    ..Background HIV-exposed uninfected children have a higher risk of infection and mortality compared to HIV-unexposed children and the reasons for this vulnerability are still under investigation...
  10. ncbi request reprint Levels of bone markers in a population of infants exposed in utero and during breastfeeding to tenofovir within an Option B+ programme in Malawi
    Marco Floridia
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    J Antimicrob Chemother 71:3206-3211. 2016
    ..We investigated bone metabolism markers in the first year of life in infants from mothers who received tenofovir, lamivudine and efavirenz during pregnancy and 12 months of breastfeeding in a national Option B+ programme in Malawi...
  11. ncbi request reprint CMV infection in a cohort of HIV-exposed infants born to mothers receiving antiretroviral therapy during pregnancy and breastfeeding
    Maria Franca Pirillo
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Vaile Regina Elena 299, 00161, Rome, Italy
    Med Microbiol Immunol . 2016
    ..Besides breastfeeding, which played a major role, also horizontal transmission between 1 and 2 years was certainly relevant in determining CMV infection acquisition...
  12. doi request reprint Emergence of lamivudine resistance hepatitis B virus mutations in pregnant women infected with HBV and HIV receiving antiretroviral prophylaxis for the prevention of mother-to-infant transmission in Malawi
    Clementina Galluzzo
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    J Med Virol 84:1553-7. 2012
    ..A high rate of lamivudine resistance was seen in this cohort of pregnant women. Follow-up of these patients will clarify if the presence of resistance has a significant impact on liver disease...
  13. doi request reprint Modifications of HIV-1 DNA and provirus-infected cells during 24 months of intermittent highly active antiretroviral therapy
    Lucia Palmisano
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    J Acquir Immune Defic Syndr 48:68-71. 2008
    ..In this study, we measured cell-associated HIV-1 DNA and provirus-infected cells during the Istituto Superiore di Sanità-Pulsed Antiretroviral Therapy (ISS-PART) clinical trial...
  14. doi request reprint Retention, transfer out and loss to follow-up two years after delivery in a cohort of HIV+ pregnant women in Malawi
    Marina Giuliano
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    Int J STD AIDS 27:462-8. 2016
    ..002). This finding suggests that discontinuation of drugs when the risk of transmission has ceased can have a negative impact on the retention in care of these women...
  15. doi request reprint Growth indices in breastfed infants pre and postnatally exposed to tenofovir compared with tenofovir-unexposed infants
    Giuseppe Liotta
    aDepartment of Biomedicine and Prevention, University of Rome Tor VergatabDepartment of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, ItalycDREAM Program, Community of S Egidio, Blantyre, MalawidLUMSA University, Rome, Italy
    AIDS 30:525-7. 2016
    ..Growth indices were similar in the two cohorts at one and 6 months but were significantly better in the first group at 12 months, suggesting no negative effect of tenofovir and a significant benefit of extended breastfeeding. ..
  16. doi request reprint Laboratory confirmation of clinically diagnosed malaria in a cohort of HIV-infected mothers and their children in Malawi
    Marina Giuliano
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Italy, DREAM Program, Community of S Egidio, Blantyre, Malawi and LUMSA University, Rome, Italy
    J Trop Pediatr 61:222-5. 2015
    ..1% (9 of 56) in children. Hemoglobin was lower in children with confirmed malaria compared to those with clinical malaria diagnosis. The results of our study support the widespread use of rapid diagnostic tests. ..
  17. pmc The impact of HBV or HCV infection in a cohort of HIV-infected pregnant women receiving a nevirapine-based antiretroviral regimen in Malawi
    Mauro Andreotti
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    BMC Infect Dis 14:180. 2014
    ....
  18. ncbi request reprint Seroprevalence of hepatitis B and C viruses among HIV-infected pregnant women in Uganda and Rwanda
    Maria F Pirillo
    Department of Drug Research and Evaluation, Istituto Superiore di Sanita, Rome, Italy
    J Med Virol 79:1797-801. 2007
    ....
  19. ncbi request reprint Residual viraemia in subjects with chronic HIV infection and viral load < 50 copies/ml: the impact of highly active antiretroviral therapy
    Lucia Palmisano
    Istituto Superiore di Sanita, Department of Drug Research and Evaluation, Rome, Italy
    AIDS 19:1843-7. 2005
    ..To determine factors associated with < 2.5 copies/ml plasma HIV RNA in subjects treated with highly active antiretroviral therapy (HAART) and with viraemia < 50 copies/ml...
  20. doi request reprint Correlation between HIV-1 viral load quantification in plasma, dried blood spots, and dried plasma spots using the Roche COBAS Taqman assay
    Mauro Andreotti
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Clin Virol 47:4-7. 2010
    ..The use of simplified methods for viral load determination could greatly increase access to treatment monitoring of HIV patients in resource-limited countries...
  21. doi request reprint Quantification of HIV-RNA from dried blood spots using the Siemens VERSANT® HIV-1 RNA (kPCR) assay
    Maria Franca Pirillo
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    J Antimicrob Chemother 66:2823-6. 2011
    ..We evaluated the performance of the VERSANT(®) HIV-1 RNA (kPCR) assay for the determination of HIV-1 viral load from dried blood spots (DBS). Assay sensitivity and correlation with plasma quantification values were assessed...
  22. pmc Viral sequence analysis of HIV-positive women and their infected children: insight on the timing of infection and on the transmission network
    Massimo Ciccozzi
    1 Department of Infectious, Parasitic, and Immune Mediated Diseases, Epidemiology Unit, Reference Centre on Phylogeny, Molecular Epidemiology, and Microbial Evolution FEMEM, Istituto Superiore di Sanita, Rome, Italy
    AIDS Res Hum Retroviruses 30:1010-5. 2014
    ..Our study showed that a coalescent-based model within a Bayesian statistical framework can provide important information that can contribute to optimizing preventive strategies...
  23. ncbi request reprint Mode of infant feeding and HIV infection in children in a program for prevention of mother-to-child transmission in Uganda
    Michele Magoni
    Istituto Superiore di Sanita, Rome, Italy
    AIDS 19:433-7. 2005
    ..To evaluate the impact of different modalities of infant feeding on HIV transmission in children in a prevention of mother-to-child transmission (PMTCT) program in an urban hospital in Uganda...
  24. doi request reprint Gender differences in the treatment of HIV infection
    Marco Floridia
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Pharmacol Res 58:173-82. 2008
    ..To obtain this goal, specific studies should be designed and females' participation in both cohort studies and clinical trials should be promoted...
  25. ncbi request reprint Inequalities in health: access to treatment for HIV/AIDS
    Marina Giuliano
    Dipartimento del Farmaco, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Ann Ist Super Sanita 43:313-6. 2007
    ..A broad, multisectorial response at national and international levels is required to guarantee access to antiretroviral drugs for all people with HIV/AIDS who need them...
  26. ncbi request reprint Selection of resistance mutations in pregnant women receiving zidovudine and lamivudine to prevent HIV perinatal transmission
    Marina Giuliano
    Laboratory of Virology, Istituto Superiore di Sanita, Rome, Italy
    AIDS 17:1570-2. 2003
    ..No nucleoside reverse transcriptase inhibitor resistance-associated mutations were detected in 50 women who received zidovudine/lamivudine intrapartum and postpartum only. No association with the risk of perinatal transmission was found...
  27. ncbi request reprint Resistance mutation patterns in plasma and breast milk of HIV-infected women receiving highly-active antiretroviral therapy for mother-to-child transmission prevention
    Mauro Andreotti
    AIDS 21:2360-2. 2007
  28. ncbi request reprint A randomized trial of 2 different 4-drug antiretroviral regimens versus a 3-drug regimen, in advanced human immunodeficiency virus disease
    Margaret A Fischl
    Department of Medicine, University of Miami School of Medicine, Miami, Florida 33101, USA
    J Infect Dis 188:625-34. 2003
    ..A 4-drug regimen containing efavirenz plus indinavir resulted in a superior virologic response, whereas one containing nelfinavir plus indinavir resulted in an inferior response and a greater likelihood of toxicity...
  29. doi request reprint Antiretroviral resistance mutations in untreated pregnant women with HIV infection in Uganda and Rwanda
    Clementina M Galluzzo
    AIDS Res Hum Retroviruses 23:1449-51. 2007
  30. doi request reprint Tumor necrosis factor-alpha, Interleukin-10, and alpha-defensins in plasma and breast milk of HIV-infected highly active antiretroviral therapy-treated and untreated pregnant women in Mozambique
    Silvia Baroncelli
    J Acquir Immune Defic Syndr 47:647-9. 2008
  31. pmc Association between cellular human immunodeficiency virus DNA level and immunological parameters in patients with undetectable plasma viremia level during highly active antiretroviral therapy
    Loredana Sarmati
    Department of Public Health and Cellular Biology, University of Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    J Clin Microbiol 43:6183-5. 2005
    ..005) CD4 counts and a prolonged duration of treatment (P = 0.001). At adjusted analysis, prolonged duration of treatment was independently associated with lower (P = 0.006) and undetectable (P < 0.001) HIV DNA values...
  32. ncbi request reprint Selection of resistance mutations in children receiving prophylaxis with lamivudine or nevirapine for the prevention of postnatal transmission of HIV
    Marina Giuliano
    J Acquir Immune Defic Syndr 42:131-3. 2006
  33. ncbi request reprint Randomized open-label trial of two simplified, class-sparing regimens following a first suppressive three or four-drug regimen
    Margaret A Fischl
    AIDS Clinical Research Unit R 60A, Department of Medicine, University of Miami School of Medicine, 1800 NW 10th Avenue, Miami, FL 33136, USA
    AIDS 21:325-33. 2007
    ..Complex antiretroviral regimens can be associated with increased toxicity and poor adherence. Our aim was to compare the efficacy and safety of switching to two simplified, class-sparing antiretroviral regimens...
  34. pmc A theme issue by, for, and about Africa: results from Ugandan programme preventing maternal transmission of HIV
    Marina Giuliano
    BMJ 331:778. 2005
  35. ncbi request reprint Efficacy of highly active antiretroviral therapy in HIV-infected, institutionalized orphaned children in Tanzania
    Claudio Blè
    Department of Infectious Diseases, S M Annunziata Hospital, ASL, Florence, Italy
    Acta Paediatr 96:1090-4. 2007