Anna Rita Ciccaglione

Summary

Affiliation: Istituto Superiore di Sanit
Country: Italy

Publications

  1. pmc A computational approach to identify point mutations associated with occult hepatitis B: significant mutations affect coding regions but not regulative elements of HBV
    Roberto Bruni
    Department of Infectious, Parasitic and Immune Mediated Diseases, Viral Hepatitis Section, Istituto Superiore di Sanita, Rome, Italy
    Virol J 8:394. 2011
  2. pmc Microarray analysis identifies a common set of cellular genes modulated by different HCV replicon clones
    Anna Rita Ciccaglione
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    BMC Genomics 9:309. 2008
  3. pmc Improving HIV-2 detection by a combination of serological and nucleic acid amplification test assays
    Anna Rita Ciccaglione
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161, Rome, Italy
    J Clin Microbiol 48:2902-8. 2010
  4. doi request reprint Evaluation of rapid tests for diagnosis of acute hepatitis E
    Paola Chionne
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    J Clin Virol 78:4-8. 2016
  5. doi request reprint Evolutionary dynamics of HBV-D1 genotype epidemic in Turkey
    Massimo Ciccozzi
    Epidemiology Unit, Department of Infectious, Parasite and Immune mediated Diseases, Italian Institute of Health, Rome, Italy
    J Med Virol 86:109-16. 2014
  6. doi request reprint Evolutionary dynamics of HBV-D7 subgenotype in Tunisia
    Massimo Ciccozzi
    Department of Infectious, Parasitic and Immune Mediated Diseases, Epidemiology Unit, Istituto Superiore di Sanita, Rome, Italy
    J Med Virol . 2016
  7. pmc An integrated approach identifies IFN-regulated microRNAs and targeted mRNAs modulated by different HCV replicon clones
    Roberto Bruni
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    BMC Genomics 12:485. 2011
  8. pmc Key Role of Sequencing to Trace Hepatitis A Viruses Circulating in Italy During a Large Multi-Country European Foodborne Outbreak in 2013
    Roberto Bruni
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanità ISS, Rome, Italy
    PLoS ONE 11:e0149642. 2016
  9. doi request reprint Hepatitis C virus genotype 4d in Southern Italy: reconstruction of its origin and spread by a phylodynamic analysis
    Massimo Ciccozzi
    Department of Infectious, Parasitic and Immunomediated Diseases, National Institute of Health, Rome, Italy
    J Med Virol 84:1613-9. 2012
  10. pmc A computational approach identifies two regions of Hepatitis C Virus E1 protein as interacting domains involved in viral fusion process
    Roberto Bruni
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    BMC Struct Biol 9:48. 2009

Collaborators

Detail Information

Publications24

  1. pmc A computational approach to identify point mutations associated with occult hepatitis B: significant mutations affect coding regions but not regulative elements of HBV
    Roberto Bruni
    Department of Infectious, Parasitic and Immune Mediated Diseases, Viral Hepatitis Section, Istituto Superiore di Sanita, Rome, Italy
    Virol J 8:394. 2011
    ..In addition, the feasibility of bioinformatics prediction models to classify HBV infections into OBI and non-OBI by molecular data was evaluated...
  2. pmc Microarray analysis identifies a common set of cellular genes modulated by different HCV replicon clones
    Anna Rita Ciccaglione
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    BMC Genomics 9:309. 2008
    ..Thus, we analysed the expression profiles of different clones of human hepatoma-derived Huh-7 cells carrying a self-replicating HCV RNA which express all viral proteins (HCV replicon system)...
  3. pmc Improving HIV-2 detection by a combination of serological and nucleic acid amplification test assays
    Anna Rita Ciccaglione
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161, Rome, Italy
    J Clin Microbiol 48:2902-8. 2010
    ....
  4. doi request reprint Evaluation of rapid tests for diagnosis of acute hepatitis E
    Paola Chionne
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    J Clin Virol 78:4-8. 2016
    ..Hepatitis E virus diagnosis still presents difficulties due to discordant results among diagnostic tests...
  5. doi request reprint Evolutionary dynamics of HBV-D1 genotype epidemic in Turkey
    Massimo Ciccozzi
    Epidemiology Unit, Department of Infectious, Parasite and Immune mediated Diseases, Italian Institute of Health, Rome, Italy
    J Med Virol 86:109-16. 2014
    ....
  6. doi request reprint Evolutionary dynamics of HBV-D7 subgenotype in Tunisia
    Massimo Ciccozzi
    Department of Infectious, Parasitic and Immune Mediated Diseases, Epidemiology Unit, Istituto Superiore di Sanita, Rome, Italy
    J Med Virol . 2016
    ..J. Med. Virol. © 2016 Wiley Periodicals, Inc...
  7. pmc An integrated approach identifies IFN-regulated microRNAs and targeted mRNAs modulated by different HCV replicon clones
    Roberto Bruni
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    BMC Genomics 12:485. 2011
    ..Thus, we compared the expression profile of 24 selected miRs in IFN-β-treated Huh-7 cells and in three different clones of Huh-7 cells carrying a self-replicating HCV RNA which express all viral proteins (HCV replicon system)...
  8. pmc Key Role of Sequencing to Trace Hepatitis A Viruses Circulating in Italy During a Large Multi-Country European Foodborne Outbreak in 2013
    Roberto Bruni
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanità ISS, Rome, Italy
    PLoS ONE 11:e0149642. 2016
    ..In the present study the molecular characterization of HAV isolates from 355 Italian cases is reported...
  9. doi request reprint Hepatitis C virus genotype 4d in Southern Italy: reconstruction of its origin and spread by a phylodynamic analysis
    Massimo Ciccozzi
    Department of Infectious, Parasitic and Immunomediated Diseases, National Institute of Health, Rome, Italy
    J Med Virol 84:1613-9. 2012
    ....
  10. pmc A computational approach identifies two regions of Hepatitis C Virus E1 protein as interacting domains involved in viral fusion process
    Roberto Bruni
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    BMC Struct Biol 9:48. 2009
    ....
  11. doi request reprint High prevalence of anti-hepatitis E virus antibodies among blood donors in central Italy, February to March 2014
    Claudia Lucarelli
    Department of Infectious Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    Euro Surveill 21:. 2016
    ..Nearly 1% of donors have acute or recent infection, implying potential transmission to blood recipients. Neither ALT nor anti-HEV IgM testing seems useful to prevent transfusion-transmitted HEV infection. ..
  12. pmc Molecular epidemiology and phylogenetic analysis of Hepatitis B virus in a group of migrants in Italy
    Umbertina Villano
    Viral Hepatitis Unit, Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    BMC Infect Dis 15:287. 2015
    ..We describe the molecular epidemiology of HBV in a chronically infected population of migrants (living in Italy), by using the phylogenetic analysis...
  13. pmc Diagnosis of HEV infection by serological and real-time PCR assays: a study on acute non-A-C hepatitis collected from 2004 to 2010 in Italy
    Angela Candido
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    BMC Res Notes 5:297. 2012
    ..In the present study, we evaluated HEV infection in patients with acute non-A-C hepatitis by an approach comparing data from Real-time PCR and serological assays...
  14. pmc Phylogeny and phylodinamic of Hepatitis C in Italy
    Massimo Ciccozzi
    Department of Infectious, Parasitic and Immunomediated Diseases, National Institute of Health, Rome, Italy
    BMC Infect Dis 12:S5. 2012
    ..Monitoring the genetic evolution of HCV is an essential step to control the local as well as global HCV epidemic and to develop efficient preventive and therapeutic strategies...
  15. doi request reprint Reconstruction of the evolutionary dynamics of the hepatitis C virus 1b epidemic in Turkey
    Massimo Ciccozzi
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Infect Genet Evol 11:863-8. 2011
    ..A coalescent-based approach to population dynamics can improve our understanding of the origin and spread of epidemics in a limited geographical area...
  16. pmc Naturally occurring mutations associated with resistance to HCV NS5B polymerase and NS3 protease inhibitors in treatment-naïve patients with chronic hepatitis C
    Angela Costantino
    Department of Infectious, Parasitic and Immune Mediated Diseases, Viral Hepatitis Unit, Istituto Superiore di Sanita, Viale Regina Elena, 299 00161, Rome, Italy
    Virol J 12:186. 2015
    ..In this study, we investigated the presence of mutations, which have been previously reported to be associated with resistance to DAAs in HCV polymerase (NS5B) and HCV protease (NS3) regions, in sera of treatment-naïve patients...
  17. pmc Surveillance of hepatitis A virus in urban sewages and comparison with cases notified in the course of an outbreak, Italy 2013
    Giuseppina La Rosa
    Department of Environment and Primary Prevention, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    BMC Infect Dis 14:419. 2014
    ....
  18. pmc Molecular characterisation of human hepatitis E virus from Italy: comparative analysis of five reverse transcription-PCR assays
    Giuseppina La Rosa
    Department of Environment and Primary Prevention, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Virol J 11:72. 2014
    ..Conventional RT-PCR followed by sequencing of PCR products can identify HEV genotype and, depending on the region, the subtype, thus helping in defining the origin of infection and tracing the source of contamination...
  19. ncbi request reprint Expression of HCV E1 protein in baculovirus-infected cells: effects on cell viability and apoptosis induction
    Anna Rita Ciccaglione
    Laboratory of Virology, Istituto Superiore di Sanita, Rome, Italy
    Intervirology 46:121-6. 2003
    ..These findings support the hypothesis that the TM domain of E1 may play a role in viral pathogenesis...
  20. doi request reprint A large prolonged outbreak of hepatitis A associated with consumption of frozen berries, Italy, 2013-14
    Gaia Scavia
    1Istituto Superiore di Sanità, Rome, Italy
    J Med Microbiol . 2017
    ..Our findings highlight the importance of considering frozen berries among the highest risk factors for HAV...
  21. pmc IFN-α regulates Blimp-1 expression via miR-23a and miR-125b in both monocytes-derived DC and pDC
    Stefania Parlato
    Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanita, Rome, Italy
    PLoS ONE 8:e72833. 2013
    ....
  22. doi request reprint Woodchuck hepatitis virus core gene deletions and proliferative responses of peripheral blood mononuclear cells stimulated by an immunodominant epitope: a viral immune escape in the woodchuck model of chronic hepatitis B?
    Stefania Taffon
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161, Rome, Italy
    Arch Virol 160:1065-73. 2015
    ....
  23. ncbi request reprint Rare HVR1-HCV genotype 1b variants in patients with B non Hodgkin's lymphoma. Comparison with viral sequences detected in cases of lymphoproliferative disorders and B cell compartmentalisation
    Stefano Dettori
    Viral Hepatitis Unit, Department of Infectious, Parasitic and Immune Mediated Disease, Istituto Superiore di Sanita, Rome
    New Microbiol 30:265-70. 2007
    ..In conclusion, the HCV predominants circulating in B-NHL cases seem to be associated with clonal selection of rare variants...
  24. doi request reprint T-cell-mediated and antigen-dependent differentiation of human monocyte into different dendritic cell subsets: a feedback control of Th1/Th2 responses
    Sabrina Mariotti
    Dipartimento Malattie Infettive, Parassitarie e Immunomediate, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    FASEB J 22:3370-9. 2008
    ..Because the APC capacities of these DCs have opposite functional consequences, a contribution in the regulation of the ongoing immune response by monocyte-derived inflammatory DCs is envisaged...