Nicola Ferrara

Summary

Affiliation: Fondazione Salvatore Maugeri
Country: Italy

Publications

  1. ncbi request reprint Insulin-induced changes in beta-adrenergic response: an experimental study in the isolated rat papillary muscle
    Nicola Ferrara
    Department of Health Sciences, University of Molise, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Campoli, Via dei Bagni Vecchi, 82037 Telese Terme, Italy
    Am J Hypertens 18:348-53. 2005
  2. ncbi request reprint Impact of aging on cardiac sympathetic innervation measured by 123I-mIBG imaging in patients with systolic heart failure
    Giuseppe Rengo
    Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme BN, Telese Terme, Italy
    Eur J Nucl Med Mol Imaging 43:2392-2400. 2016
  3. ncbi request reprint Effect of losartan in treatment of exercise-induced myocardial ischemia
    Giancarlo Longobardi
    Cardiology Division, Fondazione Salvatore Maugeri, IRCCS, Scientific Institute of Telese Terme, Telese Terme, Italy
    Am J Cardiol 100:1517-21. 2007
  4. doi request reprint Changes of plasma norepinephrine and serum N-terminal pro-brain natriuretic peptide after exercise training predict survival in patients with heart failure
    Giuseppe Rengo
    Division of Cardiology, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme BN, Italy Division of Geriatrics, Department of Translational Medical Sciences, Federico II University of Naples, Italy
    Int J Cardiol 171:384-9. 2014
  5. pmc Impact of an Innovative Educational Strategy on Medication Appropriate Use and Length of Stay in Elderly Patients
    Graziamaria Corbi
    From Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy GC, GP Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy GG, RB Division of Brain Sciences, Imperial College London, UK GP Department of Medicine and Surgery, University of Salerno, Baronissi SA, Italy GR, VC, AF Department of Translational Medical Sciences, Federico II University of Naples, Naples, Italy GR, DL, NF and Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese, Telese Terme BN, Italy GR, NF
    Medicine (Baltimore) 94:e918. 2015
  6. doi request reprint Six-minute walking test but not ejection fraction predicts mortality in elderly patients undergoing cardiac rehabilitation following coronary artery bypass grafting
    Francesco Cacciatore
    Dipartimento di Medicina Clinica e Scienze, Cardiovascolari ed Immunologiche, Cattedra di Geriatria, University of Naples Federico II, Naples, Italy
    Eur J Prev Cardiol 19:1401-9. 2012
  7. doi request reprint Hypermagnesemia predicts mortality in elderly with congestive heart disease: relationship with laxative and antacid use
    Graziamaria Corbi
    Rehabilitative Cardiology Unit of S Maugeri Foundation, Scientific Institute of Telese Campoli, IRCCS, Telese Terme, Italy
    Rejuvenation Res 11:129-38. 2008
  8. doi request reprint Increased Epicardial Adipose Tissue Volume Correlates With Cardiac Sympathetic Denervation in Patients With Heart Failure
    Valentina Parisi
    From the Department of Translational Medical Sciences V P, G R, G P, G D F, L P, G G, A C, N F, D L and Department of Advanced Biomedical Science P P F, T P, A C, University Federico II, Naples, Italy Department of Cardiology G R, G G and Department of Neurology M N, A E, Salvatore Maugeri Foundation, IRCCS, Istituto di Telese, Benevento, Italy G R, G G, M N, A E SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy S P Department of Cardiology and Cardiac Surgery, Casa di Cura San Michele, Maddaloni CE, Italy A C, M G G, F B, A D B Department of Cardiac Surgery, Ruggi D Aragona Hospital
    Circ Res 118:1244-53. 2016
  9. pmc Prognostic Value of Lymphocyte G Protein-Coupled Receptor Kinase-2 Protein Levels in Patients With Heart Failure
    Giuseppe Rengo
    From the Division of Cardiology, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme BN, Italy G R, G G, D F V, N F Division of Geriatrics, Department of Translational Medical Sciences G R, G P, G D F, V P, A C, D Liccardo, K K, G G, M L D A, C D L, N F, D Leosco, Division of Cardiology, Department of Advanced Biomedical Sciences P P F, B T, Federico II University of Naples, Naples, Italy SDN Foundation IRCCS, Institute of Diagnostic and Nuclear Development, Naples, Italy S P and Department of Pharmacology, Center of Translational Medicine, Temple University, Philadelphia, PA A C, D Liccardo, W J K
    Circ Res 118:1116-24. 2016
  10. doi request reprint Impact of diabetes mellitus on lymphocyte GRK2 protein levels in patients with heart failure
    Giuseppe Rengo
    IRCCS, Scientific Institute of Telese Terme BN, Salvatore Maugeri Foundation, Telese Terme, Italy
    Eur J Clin Invest 45:187-95. 2015

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Insulin-induced changes in beta-adrenergic response: an experimental study in the isolated rat papillary muscle
    Nicola Ferrara
    Department of Health Sciences, University of Molise, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Campoli, Via dei Bagni Vecchi, 82037 Telese Terme, Italy
    Am J Hypertens 18:348-53. 2005
    ..The aim was to investigate the ability of insulin to modulate the response to beta-adrenergic action on myocardial contractility, assessed as percentage changes of developed tension, in isolated rat papillary muscle...
  2. ncbi request reprint Impact of aging on cardiac sympathetic innervation measured by 123I-mIBG imaging in patients with systolic heart failure
    Giuseppe Rengo
    Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme BN, Telese Terme, Italy
    Eur J Nucl Med Mol Imaging 43:2392-2400. 2016
    ..However, little data are available on the impact of ageing on cardiac sympathetic nerve activity assessed by 123I-mIBG scintigraphy, in patients with HF...
  3. ncbi request reprint Effect of losartan in treatment of exercise-induced myocardial ischemia
    Giancarlo Longobardi
    Cardiology Division, Fondazione Salvatore Maugeri, IRCCS, Scientific Institute of Telese Terme, Telese Terme, Italy
    Am J Cardiol 100:1517-21. 2007
    ....
  4. doi request reprint Changes of plasma norepinephrine and serum N-terminal pro-brain natriuretic peptide after exercise training predict survival in patients with heart failure
    Giuseppe Rengo
    Division of Cardiology, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme BN, Italy Division of Geriatrics, Department of Translational Medical Sciences, Federico II University of Naples, Italy
    Int J Cardiol 171:384-9. 2014
    ..In this study, we evaluate whether changes in plasma Norepinephrine (NE) and serum N-terminal pro-brain natriuretic peptide (NT-proBNP) after exercise training predict cardiac mortality in HF patients...
  5. pmc Impact of an Innovative Educational Strategy on Medication Appropriate Use and Length of Stay in Elderly Patients
    Graziamaria Corbi
    From Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy GC, GP Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy GG, RB Division of Brain Sciences, Imperial College London, UK GP Department of Medicine and Surgery, University of Salerno, Baronissi SA, Italy GR, VC, AF Department of Translational Medical Sciences, Federico II University of Naples, Naples, Italy GR, DL, NF and Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese, Telese Terme BN, Italy GR, NF
    Medicine (Baltimore) 94:e918. 2015
    ..To evaluate the impact of an educational strategy on potentially inappropriate medications (PIMs) and length of stay in hospitalized elderly patients...
  6. doi request reprint Six-minute walking test but not ejection fraction predicts mortality in elderly patients undergoing cardiac rehabilitation following coronary artery bypass grafting
    Francesco Cacciatore
    Dipartimento di Medicina Clinica e Scienze, Cardiovascolari ed Immunologiche, Cattedra di Geriatria, University of Naples Federico II, Naples, Italy
    Eur J Prev Cardiol 19:1401-9. 2012
    ..Age-related effects on the ability of 6-min walking test (6MWT) and ejection fraction (EF) to predict mortality in coronary artery bypass grafting (CABG) patients undergoing cardiac rehabilitation (CR) is still debated...
  7. doi request reprint Hypermagnesemia predicts mortality in elderly with congestive heart disease: relationship with laxative and antacid use
    Graziamaria Corbi
    Rehabilitative Cardiology Unit of S Maugeri Foundation, Scientific Institute of Telese Campoli, IRCCS, Telese Terme, Italy
    Rejuvenation Res 11:129-38. 2008
    ..The shown relationship between hypermagnesemia and laxative/antacid use should induce physicians to pay more attention to abuse of these drugs...
  8. doi request reprint Increased Epicardial Adipose Tissue Volume Correlates With Cardiac Sympathetic Denervation in Patients With Heart Failure
    Valentina Parisi
    From the Department of Translational Medical Sciences V P, G R, G P, G D F, L P, G G, A C, N F, D L and Department of Advanced Biomedical Science P P F, T P, A C, University Federico II, Naples, Italy Department of Cardiology G R, G G and Department of Neurology M N, A E, Salvatore Maugeri Foundation, IRCCS, Istituto di Telese, Benevento, Italy G R, G G, M N, A E SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy S P Department of Cardiology and Cardiac Surgery, Casa di Cura San Michele, Maddaloni CE, Italy A C, M G G, F B, A D B Department of Cardiac Surgery, Ruggi D Aragona Hospital
    Circ Res 118:1244-53. 2016
    ..It has been reported that epicardial adipose tissue (EAT) may affect myocardial autonomic function...
  9. pmc Prognostic Value of Lymphocyte G Protein-Coupled Receptor Kinase-2 Protein Levels in Patients With Heart Failure
    Giuseppe Rengo
    From the Division of Cardiology, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme BN, Italy G R, G G, D F V, N F Division of Geriatrics, Department of Translational Medical Sciences G R, G P, G D F, V P, A C, D Liccardo, K K, G G, M L D A, C D L, N F, D Leosco, Division of Cardiology, Department of Advanced Biomedical Sciences P P F, B T, Federico II University of Naples, Naples, Italy SDN Foundation IRCCS, Institute of Diagnostic and Nuclear Development, Naples, Italy S P and Department of Pharmacology, Center of Translational Medicine, Temple University, Philadelphia, PA A C, D Liccardo, W J K
    Circ Res 118:1116-24. 2016
    ..Importantly, myocardial GRK2 levels correlate with levels found in peripheral lymphocytes of HF patients...
  10. doi request reprint Impact of diabetes mellitus on lymphocyte GRK2 protein levels in patients with heart failure
    Giuseppe Rengo
    IRCCS, Scientific Institute of Telese Terme BN, Salvatore Maugeri Foundation, Telese Terme, Italy
    Eur J Clin Invest 45:187-95. 2015
    ..Moreover, HF-related GRK2 protein overexpression promotes insulin resistance by interfering with insulin signalling. The aim of this study was to assess lymphocyte GRK2 protein levels in HF patients with and without DM...
  11. doi request reprint Association between nocturia and falls-related long-term mortality risk in the elderly
    Gianluigi Galizia
    Istituto Scientifico di Veruno Novara, Divisione di Recupero e Rieducazione Funzionale, Fondazione Salvatore Maugeri, IRCCS, Veruno Novara, Italy
    J Am Med Dir Assoc 13:640-4. 2012
    ..Moreover, the risk of falls increases with urinary disorders such as nocturia. The aim of this study was to investigate the role of nocturia in falls-related long-term mortality in elderly subjects...
  12. doi request reprint Adrenal GRK2 lowering is an underlying mechanism for the beneficial sympathetic effects of exercise training in heart failure
    Giuseppe Rengo
    Cardiology Division, Salvatore Maugeri Foundation, IRCCS, Via Bagni Vecchi, 1 82037 Telese Terme, Italy
    Am J Physiol Heart Circ Physiol 298:H2032-8. 2010
    ....
  13. ncbi request reprint Disability and 6-year mortality in elderly population. Role of visual impairment
    Francesco Cacciatore
    Department of Rehabilitation, Salvatore Maugeri Foundation, Telese Campoli Bn, Italy
    Aging Clin Exp Res 16:382-8. 2004
    ..A cross-sectional survey in a large population randomly selected in 1992 with a 6-year mortality evaluation in Campania, a region in southern Italy...
  14. pmc Is physical activity able to modify oxidative damage in cardiovascular aging?
    Graziamaria Corbi
    Department of Medicine and Health Sciences, University of Molise, Via Giovanni Paolo II, Località Tappino, 86100 Campobasso, Italy
    Oxid Med Cell Longev 2012:728547. 2012
    ....
  15. ncbi request reprint Role of sirtuins, calorie restriction and physical activity in aging
    Graziamaria Corbi
    Department of Health Sciences, Faculty of Medicine and Surgery, University of Molise, via Giovanni Paolo II Localita Tappino, 86100 Campobasso, Italy
    Front Biosci (Elite Ed) 4:768-78. 2012
    ..However, in aged rats a moderate prolonged exercise training is able to induce increase in SIRT1 activity, suggesting that this tool could counteract age-related dysfunctions...
  16. pmc β1-adrenergic receptor and sphingosine-1-phosphate receptor 1 (S1PR1) reciprocal downregulation influences cardiac hypertrophic response and progression to heart failure: protective role of S1PR1 cardiac gene therapy
    Alessandro Cannavo
    Division of Geriatrics, Department of Translational Medical Sciences A C, G R, D L, G P, N F, D L, Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases M V B, and Division of Cardiology, Department of Advanced Biomedical Sciences M C D A, R P, E D P, P C, B T, A R, Federico II University, Naples, Italy Center of Translational Medicine, Temple University, Philadelphia, PA A C, J E R, W J K Division of Cardiology, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme BN, Italy G R, C Z, N F and the Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom T M P
    Circulation 128:1612-22. 2013
    ....
  17. ncbi request reprint Cardiac rehabilitation in the elderly: patient selection and outcomes
    Nicola Ferrara
    Fondazione S Maugeri, IRCCS, Pavia, Italy
    Am J Geriatr Cardiol 15:22-7. 2006
    ..Physicians must be encouraged to prescribe cardiac rehabilitation programs for the elderly following major coronary events and coronary revascularization procedures...
  18. ncbi request reprint Angiotensin II-receptor antagonist losartan does not prevent nitroglycerin tolerance in patients with coronary artery disease
    Giancarlo Longobardi
    Division of Cardiology, Fondazione Salvatore Maugeri, IRCCS Scientific Institute of Telese Terme, Via Bagni Vecchi, 82037 Telese Termi, Italy
    Cardiovasc Drugs Ther 18:363-70. 2004
    ..001). The AT(1) antagonist Losartan administration does not prevent the development of nitrate tolerance during continuous TD-GTN therapy...
  19. doi request reprint Cholinesterase inhibitors for Parkinson's disease: a systematic review and meta-analysis
    Gennaro Pagano
    Department of Medicine and Health Sciences, School of Medicine, University of Molise, Campobasso, Italy Department of Translational Medical Sciences, Federico II University of Naples, Naples, Italy
    J Neurol Neurosurg Psychiatry 86:767-73. 2015
    ..Our objective was to conduct a systematic review of prospective, randomised controlled trials, in order to assess the efficacy and safety of ChIs compared with placebo in patients with PD...
  20. doi request reprint Elderly abuse: risk factors and nursing role
    Graziamaria Corbi
    Department of Medicine and Health Sciences, University of Molise, Via De Sanctis, snc, 86100, Campobasso, Italy
    Intern Emerg Med 10:297-303. 2015
    ..Despite the aging of the population, elderly abuse and neglect still remain hidden problems, overlooked and also underestimated in the literature...
  21. ncbi request reprint Mortality and heart rate in the elderly: role of cognitive impairment
    Francesco Cacciatore
    Istituto Scientifico di Campoli Telese, Fondazione Salvatore Maugeri, IRCCS, Benevento, Italy
    Exp Aging Res 33:127-44. 2007
    ..However, when considering all elderly subjects and those with CI, HR increase seems to have no effect on mortality. Thus, CI should be considered when focusing on HR increase as risk factor for mortality in the elderly...
  22. ncbi request reprint Exercise training promotes SIRT1 activity in aged rats
    Nicola Ferrara
    Department of Health Sciences, Faculty of Medicine, University of Molise, Campobasso, Italy
    Rejuvenation Res 11:139-50. 2008
    ..There was a similar decrease in cyclin D(2), and no changes in GADD45a mRNA expression in adipose tissue. We concluded that exercise training, which significantly increases SIRT1 activity, could counteract age-related systems impairment...
  23. pmc Potential mechanisms linking atherosclerosis and increased cardiovascular risk in COPD: focus on Sirtuins
    Graziamaria Corbi
    Department of Medicine and Health Sciences, University of Molise, via Giovanni Paolo II Loc Tappino, 86100 Campobasso, Italy
    Int J Mol Sci 14:12696-713. 2013
    ..We review the inflammatory mechanisms involved in COPD-CVD coexistence and the potential role of SIRT1 in the regulation of these systems...
  24. pmc Oral anticoagulation therapy in heart failure patients in sinus rhythm: a systematic review and meta-analysis
    Giuseppe Rengo
    Division of Cardiology, Salvatore Maugeri Foundation, IRCCS Scientific Institute of Telese Terme, Benevento, Italy
    PLoS ONE 8:e52952. 2013
    ..Anticoagulation reduces embolic event and death rates in HF patients with atrial fibrillation, but if antithrombotic therapy is beneficial in patients with HF in sinus rhythm is still debated...
  25. doi request reprint Elderly residents at risk for being victims or offenders
    Graziamaria Corbi
    Department of Medicine and Health Sciences, School of Medicine, University of Molise, Campobasso, Italy
    J Am Med Dir Assoc 13:657-9. 2012
    ....
  26. ncbi request reprint Efficacy of transdermal nitroglycerin patches evaluated by dipyridamole-induced myocardial ischemia in patients with coronary artery disease. Comparison between continuous and intermittent schedule
    Giancarlo Longobardi
    Fondazione Salvatore Maugeri, IRCCS, Rehabilitation Institute of Telese Terme, Division of Cardiology, Italy
    Cardiovasc Drugs Ther 16:535-42. 2002
    ..Moreover the dipyridamole echocardiographic stress test, besides evaluating myocardial ischemia-induced wall motion abnormalities, is adequate to assess both the efficacy and the tolerance of transdermal nitrate therapy...
  27. ncbi request reprint Biomarkes of aging
    Sonya Vasto
    Department of Health Sciences, University of Molise, Campobasso, Italy
    Front Biosci (Schol Ed) 2:392-402. 2010
    ..However, this kind of knowledge is useful to anti-ageing strategies aimed to slow ageing and to postpone death by preventing infectious diseases and delaying the onset of age-related diseases...
  28. ncbi request reprint Exercise promotes angiogenesis and improves beta-adrenergic receptor signalling in the post-ischaemic failing rat heart
    Dario Leosco
    Cattedra di Geriatria, Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Universita Federico II, Via Pansini 5, 80131 Napoli, Italy
    Cardiovasc Res 78:385-94. 2008
    ..We also explored the contribution of ameliorated beta-adrenergic receptor signalling and function on the overall improvement of cardiac contractility reserve induced by exercise...
  29. ncbi request reprint Exercise training and beta-blocker treatment ameliorate age-dependent impairment of beta-adrenergic receptor signaling and enhance cardiac responsiveness to adrenergic stimulation
    Dario Leosco
    Department of Internal Medicine, Cardiovascular Sciences and Immunology, University Federico II, Via Pansini 5, Edificio 2, 80131 Naples, Italy
    Am J Physiol Heart Circ Physiol 293:H1596-603. 2007
    ..In conclusion, we demonstrate for the first time that exercise and beta-AR blockade can similarly ameliorate beta-AR signaling in the aged heart, leading to improved beta-AR responsiveness and corresponding LV inotropic reserve...
  30. ncbi request reprint Exercise training affects age-induced changes in SOD and heat shock protein expression in rat heart
    Barbara Rinaldi
    Department of Experimental Medicine and Excellence Center of Cardiovascular Disease, Second University of Naples, Naples 80138, Italy
    Exp Gerontol 41:764-70. 2006
    ..These findings suggest that the beneficial effects on aged-related cardiovascular changes could be connected to the "anti-oxidant" effects of prolonged exercise training...
  31. ncbi request reprint Mortality and blood pressure in elderly people with and without cognitive impairment
    Francesco Cacciatore
    Cattedra di Geriatria, Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Universita degli Studi di Napoli Federico II, Naples, Italy
    Gerontology 51:53-61. 2005
    ..Objective: To verify the role of blood pressure on mortality in an elderly population with and without cognitive impairment...
  32. ncbi request reprint Exercise restores beta-adrenergic vasorelaxation in aged rat carotid arteries
    Dario Leosco
    Department of Clinic Medicine, University of Naples Federico II, Via Sergio Pansini 5, 80131 Naples, Italy
    Am J Physiol Heart Circ Physiol 285:H369-74. 2003
    ..Exercise restores this response and reverts age-related modification in beta-ARs and beta-ARK. Our data support an important role for beta-ARK in vascular beta-AR vasorelaxation...
  33. ncbi request reprint Cardioprotective effect of ischemic preconditioning is preserved in food-restricted senescent rats
    Pasquale Abete
    Cattedra di Geriatria, Dipartmento di Medicina Clinica, Scienze Cardiovasculari ed Immunologiche, Università degli studi di Napoli FedericoII, Naples, Italy
    Am J Physiol Heart Circ Physiol 282:H1978-87. 2002
    ..Thus caloric restriction may restore PC in the aging heart probably via increased norepinephrine release...
  34. ncbi request reprint Echocardiographic evaluation of left ventricular end-systolic elastance in the elderly
    Domenico De Santis
    Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Universita degli Studi di Napoli Federico II, Via S Pansini, 5, 80131 Naples, Italy
    Eur J Heart Fail 7:829-33. 2005
    ..However, important changes in systolic function may also occur. Left ventricular end-systolic elastance (E(es)) is a major determinant of cardiac systolic function and ventricular-arterial interaction...
  35. ncbi request reprint Body mass index and preinfarction angina in elderly patients with acute myocardial infarction
    Pasquale Abete
    Cattedra di Geriatria, Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Università degli Studi di Naples Federico II, Naples, Italy
    Am J Clin Nutr 78:796-801. 2003
    ..Experimental evidence indicates that caloric restriction may restore ischemic preconditioning in aged animals...